6173 results
The British journal of dermatology,
Volume 189, Issue 1, 1 1 2023, Pages 129-147
Investigator Global Assessment for impetiginization in atopic dermatitis: development and initial reliability testing.
Ragamin A, Tupker RA, de Graaf M, Rustemeyer T, Pasmans SGMA, Schappin R, Schuttelaar MLA
Abstract
International journal of cardiology. Congenital heart disease,
Volume 13, 30 5 2023, Pages 100465
An unusual case of unilateral vascular hypoplasia in an adult patient - late diagnosis of PHACE syndrome.
Regeer MV, Stöger JL, Bökenkamp R, Lakeman IMM, Hazekamp MG, Kiѐs P, Egorova AD, Jongbloed MRM
A case of unilateral vascular hypoplasia is presented. A female patient was born with a complex aortic arch anatomy - a double aortic arch with an interrupted left arch. Surgical correction was performed at the age of 3 months. The patient was also noted to have had an ipsilateral large infantile haemangioma. These findings raised the suspicion of the diagnosis of PHACE syndrome. PHACE syndrome is an acronym for Posterior fossa abnormalities, Haemangioma, Arterial anomalies, Cardiac anomalies an...
Abstract
Cited 3 times since 2023 (1.7 per year)
source: EuropePMC
Stem cell reports,
Volume 18, Issue 7, 29 5 2023, Pages 1421-1435
Single-cell analysis of human fetal epicardium reveals its cellular composition and identifies CRIP1 as a modulator of EMT.
Streef TJ, Groeneveld EJ, van Herwaarden T, Hjortnaes J, Goumans MJ, Smits AM
The epicardium plays an essential role in cardiogenesis by providing cardiac cell types and paracrine cues to the developing myocardium. The human adult epicardium is quiescent, but recapitulation of developmental features may contribute to adult cardiac repair. The cell fate of epicardial cells is proposed to be determined by the developmental persistence of specific subpopulations. Reports on this epicardial heterogeneity have been inconsistent, and data regarding the human developing epicardi...
Abstract
Cited 3 times since 2023 (1.7 per year)
source: EuropePMC
Journal of the mechanical behavior of biomedical materials,
Volume 144, 28 4 2023, Pages 105980
Cyclic strain has antifibrotic effects on the human cardiac fibroblast transcriptome in a human cardiac fibrosis-on-a-chip platform.
Bracco Gartner TCL, Wang Y, Leiteris L, van Adrichem I, Marsman J, Goumans MJ, Bouten CVC, Sluijter JPG, den Toonder JMJ, Suyker WJL, Hjortnaes J
In cardiac fibrosis, in response to stress or injury, cardiac fibroblasts deposit excessive amounts of collagens which contribute to the development of heart failure. The biochemical stimuli in this process have been extensively studied, but the influence of cyclic deformation on the fibrogenic behavior of cardiac fibroblasts in the ever-beating heart is not fully understood. In fact, most investigated mechanotransduction pathways in cardiac fibroblasts seem to ultimately have profibrotic effect...
Abstract
Cited 7 times since 2023 (3.9 per year)
source: EuropePMC
International journal of molecular sciences,
Volume 24, Issue 13, 28 4 2023, Pages 10825
Building a Scaffold for Arteriovenous Fistula Maturation: Unravelling the Role of the Extracellular Matrix.
Laboyrie SL, de Vries MR, Bijkerk R, Rotmans JI
Vascular access is the lifeline for patients receiving haemodialysis as kidney replacement therapy. As a surgically created arteriovenous fistula (AVF) provides a high-flow conduit suitable for cannulation, it remains the vascular access of choice. In order to use an AVF successfully, the luminal diameter and the vessel wall of the venous outflow tract have to increase. This process is referred to as AVF maturation. AVF non-maturation is an important limitation of AVFs that contributes to their...
Abstract
Cited 3 times since 2023 (1.7 per year)
source: EuropePMC
Pathology, research and practice,
Volume 248, 28 4 2023, Pages 154620
Intrinsic histological and morphological abnormalities of the pediatric thoracic aorta in bicuspid aortic valve patients are predictive for future aortopathy.
Grewal N, Klautz RJM, Poelmann RE
Background: Patients with a bicuspid aortic valve (BAV) have an increased risk to develop aortic complications. Many studies are pointing towards a possible embryonic explanation for the development of both a bicuspid aortic valve as well as a defective ascending aortic wall in these patients. The fetal and newborn ascending aortic wall has however scarcely been studied in bicuspid aortic valve patients. We hypothesize that early histopathological defects might already be visible in the fetal an...
Abstract
Annals of vascular surgery,
Volume 98, 28 4 2023, Pages 388-397
Pilot Study on Feasibility and Outcome of a Nerve-Preserving Aortoiliac Exposure Technique.
van Schaik J, Witt D, Albers L, Wever J, Elzevier H, Hamming J
Background: Dysfunctional ejaculation is a common complication following open aortoiliac aneurysm surgery. It may occur in 49-63% of patients and is caused by iatrogenic damage to the sympathetic lumbar splanchnic nerves and superior hypogastric plexus. A nerve-preserving operative technique based on a unilateral right-sided approach to the abdominal aorta, was implemented in clinical practice. The aim of this pilot study was to establish the safety and feasibility of the technique, and whether...
Abstract
Cited 3 times since 2023 (1.6 per year)
source: EuropePMC
Angiology,
Volume 75, Issue 9, 26 4 2023, Pages 884-892
Near-Infrared Fluorescence Imaging With Indocyanine Green to Predict Clinical Outcome After Revascularization in Lower Extremity Arterial Disease.
Tange FP, van den Hoven P, van Schaik J, Schepers A, van der Bogt KEA, van Rijswijk CSP, Putter H, Vahrmeijer AL, Hamming JF, van der Vorst JR
Contemporary quality control methods are often insufficient in predicting clinical outcomes after revascularization in lower extremity arterial disease (LEAD) patients. This study evaluates the potential of near-infrared fluorescence imaging with indocyanine green to predict the clinical outcome following revascularization. Near-infrared fluorescence imaging was performed before and within 5 days following the revascularization procedure. Clinical improvement was defined as substantial improveme...
Abstract
Cited 7 times since 2023 (3.8 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 10, 26 4 2023, Pages 1093201
The potential of sodium-glucose cotransporter 2 inhibitors for the treatment of systemic right ventricular failure in adults with congenital heart disease.
Neijenhuis RML, Nederend M, Jongbloed MRM, Kiès P, Rotmans JI, Vliegen HW, Jukema JW, Egorova AD
Aims: Given the compelling evidence on the effectiveness of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in the conventional heart failure population, SGLT2i deserve exploration in systemic right ventricular (sRV) failure. The initial experience with dapagliflozin in sRV failure patients is described, with a focus on tolerability and short-term effects on clinical outcomes. Methods and results: Ten patients (70% female, median age 50 years [46.5-52]) with symptomatic sRV failure who receiv...
Abstract
Annals of vascular surgery,
Volume 98, 23 4 2023, Pages 87-101
Perspectives of Patients and Professionals on Patient Education in Complex Endovascular Aortic Repair.
Warmerdam B, Oomen F, Hilt A, Melles M, Eefting D, Hamming J, van der Vorst J, van Schaik J
Background: Misinterpretation of patient preferences in perioperative education can lead to an undesired treatment decision. This explorative interview study presents differences in perspectives of patients and professionals on patient education in complex endovascular aortic aneurysm management. Methods: Using convenience sampling, a cross-sectional interview study was performed among patients who were in various stages of the decision-making process for complex endovascular aortic repair. Five...
Abstract
JACC. Cardiovascular interventions,
Volume 16, Issue 14, 21 3 2023, Pages 1813-1815
Retrograde Use of Intravascular Lithotripsy in Anterograde Uncrossable In-Stent Chronic Occlusion: "Retrotripsy Technique".
Montero-Cabezas JM, Al Amri I, van Oort MJH, Bingen BO, Scherptong RWC, van der Kley F
Abstract
Cited 5 times since 2023 (2.7 per year)
source: EuropePMC
Journal of internal medicine,
Volume 294, Issue 3, 21 3 2023, Pages 347-357
Light transmittance in human atrial tissue and transthoracic illumination in rats support translatability of optogenetic cardioversion of atrial fibrillation.
Nyns ECA, Portero V, Deng S, Jin T, Harlaar N, Bart CI, van Brakel TJ, Palmen M, Hjortnaes J, Ramkisoensing AA, Zhang GQ, Poelma RH, Ördög B, de Vries AAF, Pijnappels DA
Background: Optogenetics could offer a solution to the current lack of an ambulatory method for the rapid automated cardioversion of atrial fibrillation (AF), but key translational aspects remain to be studied. Objective: To investigate whether optogenetic cardioversion of AF is effective in the aged heart and whether sufficient light penetrates the human atrial wall. Methods: Atria of adult and aged rats were optogenetically modified to express light-gated ion channels (i.e., red-activatable ch...
Abstract
Cited 4 times since 2023 (2.2 per year)
source: EuropePMC
BMC ophthalmology,
Volume 23, Issue 1, 16 3 2023, Pages 279
Effect of alirocumab on cataracts in patients with acute coronary syndromes.
Suc G, Schwartz GG, Goodman SG, Jukema JW, Manvelian G, Poulouin Y, Pordy R, Scemama M, Szarek M, Steg PG, ODYSSEY OUTCOMES Investigators
Background: Some data suggest that low levels of low-density lipoprotein cholesterol (LDL-C) are associated with risk of cataracts. Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors reduce LDL-C below levels achieved with statins alone. We determined whether the incidence of cataracts was influenced by treatment with the PCSK9 inhibitor alirocumab versus placebo, and whether that incidence was affected by achieved LDL-C levels. Methods: The ODYSSEY OUTCOMES trial (NCT01663402) com...
Abstract
Cited 3 times since 2023 (1.6 per year)
source: EuropePMC
Frontiers in medicine,
Volume 10, 16 3 2023, Pages 1112573
Endoglin and squamous cell carcinomas.
Hakuno SK, Janson SGT, Trietsch MD, de Graaf M, de Jonge-Muller E, Crobach S, Harryvan TJ, Boonstra JJ, Dinjens WNM, Slingerland M, Hawinkels LJAC
Despite the fact that the role of endoglin on endothelial cells has been extensively described, its expression and biological role on (epithelial) cancer cells is still debatable. Especially its function on squamous cell carcinoma (SCC) cells is largely unknown. Therefore, we investigated SCC endoglin expression and function in three types of SCCs; head and neck (HNSCC), esophageal (ESCC) and vulvar (VSCC) cancers. Endoglin expression was evaluated in tumor specimens and 14 patient-derived cell...
Abstract
Cited 15 times since 2023 (8.1 per year)
source: EuropePMC
Science (New York, N.Y.),
Volume 380, Issue 6650, 15 3 2023, Pages 1155-1160
Widespread diversity deficits of coral reef sharks and rays.
Simpfendorfer CA, Heithaus MR, Heupel MR, MacNeil MA, Meekan M, Harvey E, Sherman CS, Currey-Randall LM, Goetze JS, Kiszka JJ, Rees MJ, Speed CW, Udyawer V, Bond ME, Flowers KI, Clementi GM, Valentin-Albanese J, Adam MS, Ali K, Asher J, Aylagas E, Beaufort O, Benjamin C, Bernard ATF, Berumen ML, Bierwagen S, Birrell C, Bonnema E, Bown RMK, Brooks EJ, Brown JJ, Buddo D, Burke PJ, Cáceres C, Cambra M, Cardeñosa D, Carrier JC, Casareto S, Caselle JE, Charloo V, Cinner JE, Claverie T, Clua EEG, Cochran JEM, Cook N, Cramp JE, D'Alberto BM, de Graaf M, Dornhege MC, Espinoza M, Estep A, Fanovich L, Farabaugh NF, Fernando D, Ferreira CEL, Fields CYA, Flam AL, Floros C, Fourqurean V, Gajdzik L, Barcia LG, Garla R, Gastrich K, George L, Giarrizzo T, Graham R, Guttridge TL, Hagan V, Hardenstine RS, Heck SM, Henderson AC, Heithaus P, Hertler H, Padilla MH, Hueter RE, Jabado RW, Joyeux JC, Jaiteh V, Johnson M, Jupiter SD, Kaimuddin M, Kasana D, Kelley M, Kessel ST, Kiilu B, Kirata T, Kuguru B, Kyne F, Langlois T, Lara F,
A global survey of coral reefs reveals that overfishing is driving resident shark species toward extinction, causing diversity deficits in reef elasmobranch (shark and ray) assemblages. Our species-level analysis revealed global declines of 60 to 73% for five common resident reef shark species and that individual shark species were not detected at 34 to 47% of surveyed reefs. As reefs become more shark-depleted, rays begin to dominate assemblages. Shark-dominated assemblages persist in wealthy n...
Abstract
The Journal of cardiovascular surgery,
Volume 64, Issue 6, 12 2 2023, Pages 634-644
Outcomes of Omniflow® II prosthesis used for revascularization in the femoral tract both in infected and non-infected setting.
Liesker DJ, Gareb B, Speijers MJ, VAN DER Vorst JR, Salemans PB, Tutein Nolthenius RP, Zeebregts CJ, Saleem BR
Background: Evidence regarding the outcomes of Omniflow® II prosthesis in peripheral arterial revascularization at different anatomical sites and for different indications is scarce. Therefore, the aim of this study was to evaluate the outcomes of the Omniflow® II used at various positions within the femoral tract both in infected and non-infected setting. Methods: Patients who underwent reconstructive lower leg vascular surgery with implantation of an Omniflow® II from 2014 until 2021 at five m...
Abstract
Cited 5 times since 2023 (2.7 per year)
source: EuropePMC
BMJ open,
Volume 13, Issue 6, 8 2 2023, Pages e071822
Ruling out acute coronary syndrome in primary care with a clinical decision rule and a capillary, high-sensitive troponin I point of care test: study protocol of a diagnostic RCT in the Netherlands (POB HELP).
van den Bulk S, Petrus AHJ, Willemsen RTA, Boogers MJ, Meeder JG, Rahel BM, van den Akker-van Marle ME, Numans ME, Dinant GJ, Bonten TN
Introduction: Chest pain is a common reason for consultation in primary care. To rule out acute coronary syndrome (ACS), general practitioners (GP) refer 40%-70% of patients with chest pain to the emergency department (ED). Only 10%-20% of those referred, are diagnosed with ACS. A clinical decision rule, including a high-sensitive cardiac troponin-I point-of-care test (hs-cTnI-POCT), may safely rule out ACS in primary care. Being able to safely rule out ACS at the GP level reduces referrals and...
Abstract
Cited 13 times since 2023 (6.9 per year)
source: EuropePMC
Surgical endoscopy,
Volume 37, Issue 9, 7 1 2023, Pages 6824-6833
Quantification of indocyanine green near-infrared fluorescence bowel perfusion assessment in colorectal surgery.
Faber RA, Tange FP, Galema HA, Zwaan TC, Holman FA, Peeters KCMJ, Tanis PJ, Verhoef C, Burggraaf J, Mieog JSD, Hutteman M, Keereweer S, Vahrmeijer AL, van der Vorst JR, Hilling DE
Background: Indocyanine green near-infrared fluorescence bowel perfusion assessment has shown its potential benefit in preventing anastomotic leakage. However, the surgeon's subjective visual interpretation of the fluorescence signal limits the validity and reproducibility of the technique. Therefore, this study aimed to identify objective quantified bowel perfusion patterns in patients undergoing colorectal surgery using a standardized imaging protocol. Method: A standardized fluorescence...
Abstract
European heart journal. Digital health,
Volume 4, Issue 4, 7 1 2023, Pages 347-356
Mobile health for cardiovascular risk management after cardiac surgery: results of a sub-analysis of The Box 2.0 study.
Biersteker TE, Boogers MJ, Schalij MJ, Braun J, Groenwold RHH, Atsma DE, Treskes RW
Aims: Lowering low-density lipoprotein (LDL-C) and blood pressure (BP) levels to guideline recommended values reduces the risk of major adverse cardiac events in patients who underwent coronary artery bypass grafting (CABG). To improve cardiovascular risk management, this study evaluated the effects of mobile health (mHealth) on BP and cholesterol levels in patients after standalone CABG. Methods and results: This study is a post hoc analysis of an observational cohort study among 228 adult pati...
Abstract
European heart journal. Case reports,
Volume 7, Issue 6, 7 1 2023, Pages ytad269
Atrioventricular nodal reentry tachycardia in pregnancy: 'I have ice for you'.
Abou R, Louwe LA, Jukema JW, Kortekaas KA
Background: Pregnancy is a known trigger of novel and pre-existing supraventricular tachyarrhythmias. We present a case of a stable pregnant patient presenting with atrioventricular nodal reentry tachycardia (AVNRT) and application of the 'facial ice immersion technique'. Case summary: A 37-year-old pregnant woman presented with recurrent AVNRT. Due to unsuccessful attempts of conventional vagal manoeuvres (VMs) and refusal of pharmacological agents, we successfully performed a non-con...
Abstract
