6173 results
Cited 16 times since 2002 (0.7 per year)
source: EuropePMC
Radiology,
Volume 225, Issue 3, 1 1 2002, Pages 701-706
Long-term prognostic value of dobutamine stress 99mTc-sestamibi SPECT: single-center experience with 8-year follow-up.
Schinkel AF, Elhendy A, Van Domburg RT, Bax JJ, Valkema R, Roelandt JR, Poldermans D
Purpose: To determine the long-term prognostic value of dobutamine stress technetium 99m (99mTc)-labeled sestamibi single photon emission computed tomography (SPECT) in patients with limited exercise capacity. Materials and methods: Clinical data and SPECT results were analyzed in 531 consecutive patients. Follow-up was successful in 528 (99.4%) patients; 55 underwent early revascularization and were excluded. Normal or abnormal findings were considered in the absence or presence of fixed and/or...
Abstract
Cited 57 times since 2002 (2.5 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 40, Issue 12, 1 1 2002, Pages 2182-2188
Left ventricular remodeling early after aortic valve replacement: differential effects on diastolic function in aortic valve stenosis and aortic regurgitation.
Lamb HJ, Beyerbacht HP, de Roos A, van der Laarse A, Vliegen HW, Leujes F, Bax JJ, van der Wall EE
Objectives: The aim of this study was to evaluate the effect of aortic valve replacement (AVR) on left ventricular (LV) function and LV remodeling, comparing patients with aortic valve stenosis to patients with aortic regurgitation. Background: Aortic valve disease is associated with eccentric or concentric LV hypertrophy and changes in LV function. The relationship between LV geometry and LV function and the effect of LV remodeling after AVR on diastolic filling, in patients with aortic valve s...
Abstract
Cited 11 times since 2002 (0.5 per year)
source: EuropePMC
Journal of vascular surgery,
Volume 36, Issue 6, 1 1 2002, Pages 1237-1247
Ingrowth of aorta vascular cells into basic fibroblast growth factor-impregnated vascular prosthesis material: a porcine and human in vitro study on blood vessel prosthesis healing.
van der Bas JM, Quax PH, van den Berg AC, van Hinsbergh VW, van Bockel JH
Objective: One of the most life-threatening vascular diseases is rupture of an abdominal aneurysm. The conventional treatment is based on surgical reconstruction. An alternative treatment is endovascular aneurysm repair (EVAR). Despite many advantages, one of the problems of EVAR is endoleakage from deficient healing between the aortic neck and the fabric of the endograft. We hypothesize that better healing, achieved with induction of vascular cell ingrowth into the graft material, would lead to...
Abstract
Cited 25 times since 2002 (1.1 per year)
source: EuropePMC
American heart journal,
Volume 144, Issue 5, 1 1 2002, Pages 760-768
A meta-analysis of the angiotensin-converting enzyme gene polymorphism and restenosis after percutaneous transluminal coronary revascularization: evidence for publication bias.
Agema WR, Jukema JW, Zwinderman AH, van der Wall EE
Background: The insertion/deletion polymorphism of the gene encoding angiotensin-converting enzyme is a controversial risk factor for restenosis after percutaneous transluminal coronary revascularization in patients. Genetic association studies addressing this issue are frequently hampered by insufficient power. Therefore, we conducted a meta-analysis of this association, taking into account the possibility of publication bias. Methods: We used the MEDLINE database and reviewed citations in rele...
Abstract
Cited 34 times since 2002 (1.5 per year)
source: EuropePMC
RNA (New York, N.Y.),
Volume 8, Issue 11, 1 1 2002, Pages 1428-1443
The human La (SS-B) autoantigen interacts with DDX15/hPrp43, a putative DEAH-box RNA helicase.
Fouraux MA, Kolkman MJ, Van der Heijden A, De Jong AS, Van Venrooij WJ, Pruijn GJ
The human La (SS-B) autoantigen is an abundantly expressed putative RNA chaperone, functioning in various intracellular processes involving RNA. To further explore the molecular mechanisms by which La functions in these processes, we performed large-scale immunoprecipitations of La from HeLa S100 extracts using the anti-La monoclonal antibody SW5. La-associated proteins were subsequently identified by sequence analysis. This approach allowed the identification of DDX15 as a protein interacting w...
Abstract
Cited 1991 times since 2002 (88.5 per year)
source: EuropePMC
Lancet (London, England),
Volume 360, Issue 9346, 1 1 2002, Pages 1623-1630
Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial.
Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Cobbe SM, Ford I, Gaw A, Hyland M, Jukema JW, Kamper AM, Macfarlane PW, Meinders AE, Norrie J, Packard CJ, Perry IJ, Stott DJ, Sweeney BJ, Twomey C, Westendorp RG, PROSPER study group PROspective Study of Pravastatin in the Elderly at Risk
Background: Although statins reduce coronary and cerebrovascular morbidity and mortality in middle-aged individuals, their efficacy and safety in elderly people is not fully established. Our aim was to test the benefits of pravastatin treatment in an elderly cohort of men and women with, or at high risk of developing, cardiovascular disease and stroke. Methods: We did a randomised controlled trial in which we assigned 5804 men (n=2804) and women (n=3000) aged 70-82 years with a history of, or ri...
Abstract
Cited 55 times since 2002 (2.4 per year)
source: EuropePMC
Archives of pediatrics & adolescent medicine,
Volume 156, Issue 11, 1 1 2002, Pages 1143-1148
Employment in adults with congenital heart disease.
Kamphuis M, Vogels T, Ottenkamp J, Van Der Wall EE, Verloove-Vanhorick SP, Vliegen HW
Objective: To evaluate job participation, career-related problems, and actual job problems in adults with complex congenital heart disease (CHD) compared with adults with mild CHD and reference groups. Design: Cross-sectional study. Setting: Patients were randomly selected from the archives of the Department of Pediatric Cardiology, Leiden University Medical Center, Leiden, the Netherlands. Patients and main outcome measures: In total, 76 patients with complex CHD and 80 with mild CHD (age range...
Abstract
Cited 5 times since 2002 (0.2 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 124, Issue 5, 1 1 2002, Pages 984-990
The morphologic nature of noncommitted ventricular septal defects in specimens with double-outlet right ventricle.
Beekman RP, Bartelings MM, Hazekamp MG, Gittenberger-De Groot AC, Ottenkamp J
Background: Lev's contribution to the understanding of the morphology of hearts with double-outlet right ventricle and the surgical feasibility for correction is important and remains in current use. However, the term noncommitted ventricular septal defect remains enigmatic. The aim of this study was to elucidate the morphologic nature of the noncommitted ventricular septal defect in view of its surgical implications. Methods: We examined 67 specimens with double-outlet right ventricle, foc...
Abstract
Cited 26 times since 2002 (1.2 per year)
source: EuropePMC
Circulation research,
Volume 91, Issue 10, 1 1 2002, Pages 945-952
Gene transfer of the urokinase-type plasminogen activator receptor-targeted matrix metalloproteinase inhibitor TIMP-1.ATF suppresses neointima formation more efficiently than tissue inhibitor of metalloproteinase-1.
Lamfers ML, Grimbergen JM, Aalders MC, Havenga MJ, de Vries MR, Huisman LG, van Hinsbergh VW, Quax PH
Proteases of the plasminogen activator (PA) and matrix metalloproteinase (MMP) system play an important role in smooth muscle cell (SMC) migration and neointima formation after vascular injury. Inhibition of either PAs or MMPs has previously been shown to result in decreased neointima formation in vivo. To inhibit both protease systems simultaneously, a novel hybrid protein, TIMP-1.ATF, was constructed consisting of the tissue inhibitor of metalloproteinase-1 (TIMP-1) domain, as MMP inhibitor, l...
Abstract
Cited 46 times since 2002 (2 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 88, Issue 5, 1 1 2002, Pages 515-519
ECG predictors of ventricular arrhythmias and biventricular size and wall mass in tetralogy of Fallot with pulmonary regurgitation.
Helbing WA, Roest AA, Niezen RA, Vliegen HW, Hazekamp MG, Ottenkamp J, de Roos A, van der Wall EE
Background: In patients with the tetralogy of Fallot, QRS prolongation predicts malignant ventricular arrhythmias. QRS prolongation may result from right ventricular dilatation. The relation of ECG markers to biventricular wall mass and volumes has not been assessed. Objective: To investigate the relations of surface ECG markers of depolarisation and repolarisation to right and left ventricular volume and biventricular wall mass. Methods: 37 Fallot patients (mean (SD) age 17 (9) years) were stud...
Abstract
Cited 19 times since 2002 (0.8 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 124, Issue 5, 1 1 2002, Pages 1038-1040
Bovine jugular vein thrombosis in the Fontan circulation.
Schoof PH, Koch AD, Hazekamp MG, Waterbolk TW, Ebels T, Dion RA
Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 9, Issue 6, 1 1 2002, Pages 675-677
Prognostic value of perfusion-FDG mismatch in ischemic cardiomyopathy.
Bax JJ, Visser FC, Poldermans D, Elhendy A, Boersma E, Visser CA, Roelandt JR
Abstract
Cited 18 times since 2002 (0.8 per year)
source: EuropePMC
The New England journal of medicine,
Volume 347, Issue 22, 1 1 2002, Pages 1803-4; author reply 1803-4
Cardiac resynchronization therapy for heart failure.
Bax JJ, Van der Wall EE, Schalij MJ
Abstract
Cited 38 times since 2002 (1.7 per year)
source: EuropePMC
Journal of virology,
Volume 76, Issue 21, 1 1 2002, Pages 10829-10840
Characterization of two new structural glycoproteins, GP(3) and GP(4), of equine arteritis virus.
Wieringa R, de Vries AA, Raamsman MJ, Rottier PJ
Equine arteritis virus (EAV) is an enveloped, positive-stranded RNA virus belonging to the family Arteriviridae of the order Nidovirales. Four envelope proteins have hitherto been identified in EAV particles: the predominant membrane proteins M and G(L), the unglycosylated small envelope protein E, and the nonabundant membrane glycoprotein G(S). In this study, we established that the products of EAV open reading frame 3 (ORF3) and ORF4 (designated GP(3) and GP(4), respectively) are also minor st...
Abstract
Cited 26 times since 2002 (1.2 per year)
source: EuropePMC
American heart journal,
Volume 144, Issue 5, 1 1 2002, Pages 865-869
Assessment of residual myocardial viability in regions with chronic electrocardiographic Q-wave infarction.
Schinkel AF, Bax JJ, Boersma E, Elhendy A, Vourvouri EC, Roelandt JR, Poldermans D
Background: Q waves on the electrocardiogram are often considered to be reflective of irreversibly scarred myocardium due to antecedent transmural myocardial infarction. However, there are some indications that residual viable tissue may be present in Q-wave-infarcted regions. It is clinically relevant to know how many Q-wave regions contain viable tissue because these patients may benefit from revascularization in terms of improvement of function and long-term survival. Methods: Patients (n = 1...
Abstract
Cited 20 times since 2002 (0.9 per year)
source: EuropePMC
Journal of virology,
Volume 76, Issue 21, 1 1 2002, Pages 10734-10744
Efficient generation and amplification of high-capacity adeno-associated virus/adenovirus hybrid vectors.
Gonçalves MA, van der Velde I, Janssen JM, Maassen BT, Heemskerk EH, Opstelten DJ, Knaän-Shanzer S, Valerio D, de Vries AA
Effective gene therapy is dependent on safe gene delivery vehicles that can achieve efficient transduction and sustained transgene expression. We are developing a hybrid viral vector system that combines in a single particle the large cloning capacity and efficient cell cycle-independent nuclear gene delivery of adenovirus (Ad) vectors with the long-term transgene expression and lack of viral genes of adeno-associated virus (AAV) vectors. The strategy being pursued relies on coupling the AAV DNA...
Abstract
Cited 5 times since 2002 (0.2 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 9, Issue 6, 1 1 2002, Pages 587-593
Safety and feasibility of cardiac FDG SPECT following oral administration of Acipimox, a nicotinic acid derivative: Comparison of image quality with hyperinsulinemic euglycemic clamping in nondiabetic patients.
Bax JJ, Visser FC, Poldermans D, Van Lingen A, Elhendy A, Boersma E, Sloof GW, Visser CA
Background: Image quality of cardiac fluorine-18-deoxyglucose (FDG) studies is highly dependent on the metabolic conditions during the study; hyperinsulinemic euglycemic clamping ensures adequate image quality. However, the approach is time-consuming. Data in a small number of patients suggest that oral administration of a nicotinic acid derivative (Acipimox, 250 mg; Byk, The Netherlands) results in good image quality. Methods and results: The safety and image quality of cardiac FDG single photo...
Abstract
Cited 4 times since 2002 (0.2 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 22, Issue 5, 1 1 2002, Pages 802-807
Structural degeneration of pulmonary homografts used as aortic valve substitute underlines early graft failure.
Koolbergen DR, Hazekamp MG, de Heer E, van Hoorn F, Huysmans HA, Bruijn JA, Dion RA
Objectives: The limited availability of donor valves and experimental evidence that pulmonary valves can withstand systemic pressure made us use cryopreserved pulmonary homografts as aortic valve substitutes. We observed a high incidence of early reoperation because of severe graft insufficiency due to cuspal tears. The mid-term results are evaluated in this study and histological analysis of explanted homografts is performed to investigate the cause of graft failure. Methods: From December 1991...
Abstract
Cited 75 times since 2002 (3.3 per year)
source: EuropePMC
The American journal of cardiology,
Volume 90, Issue 10, 1 1 2002, Pages 1157-1160
Usefulness of dynamic multislice computed tomography of left ventricular function in unstable angina pectoris and comparison with echocardiography.
Dirksen MS, Bax JJ, de Roos A, Jukema JW, van der Geest RJ, Geleijns K, Boersma E, van der Wall EE, Lamb HJ
Abstract
Cited 48 times since 2002 (2.1 per year)
source: EuropePMC
Circulation research,
Volume 91, Issue 7, 1 1 2002, Pages 577-584
Accelerated atherosclerosis and calcification in vein grafts: a study in APOE*3 Leiden transgenic mice.
Lardenoye JH, de Vries MR, Löwik CW, Xu Q, Dhore CR, Cleutjens JP, van Hinsbergh VW, van Bockel JH, Quax PH
Vein grafts fail due to development of intimal hyperplasia and accelerated atherosclerosis. Many murine genetic models in which genes are overexpressed, deleted, or mutated have been introduced recently. Therefore, mouse models are very well suited to dissect the relative contribution of different genes in the development of accelerated atherosclerosis. In the present study, we evaluated whether accelerated atherosclerosis in human vein grafts could be mimicked in hypercholesterolemic APOE*3 Lei...
Abstract
