7178 results
Cited 10 times since 2021 (2.7 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 29, Issue 11, 7 1 2021, Pages 557-565
2020 ESC Guidelines on acute coronary syndrome without ST-segment elevation : Recommendations and critical appraisal from the Dutch ACS and Interventional Cardiology working groups.
Arslan F, Damman P, Zwart B, Appelman Y, Voskuil M, de Vos A, van Royen N, Jukema JW, Waalewijn R, Hermanides RS, Woudstra P, Ten Cate T, Lemkes JS, Vink MA, Balder W, van der Wielen MLJ, Vlaar PJ, van der Heijden DJ, Assa S, van 't Hof AW, Ten Berg JM
Recently, the European Society of Cardiology (ESC) has updated its guidelines for the management of patients with acute coronary syndrome (ACS) without ST-segment elevation. The current consensus document of the Dutch ACS working group and the Working Group of Interventional Cardiology of the Netherlands Society of Cardiology aims to put the 2020 ESC Guidelines into the Dutch perspective and to provide practical recommendations for Dutch cardiologists, focusing on antiplatelet therapy, risk asse...
Abstract
Cited 2 times since 2021 (0.5 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 8, 7 1 2021, Pages 699492
Prognostic Value of Natriuretic Peptides for All-Cause Mortality, Right Ventricular Failure, Major Adverse Events, and Myocardial Recovery in Advanced Heart Failure Patients Receiving a Left Ventricular Assist Device: A Systematic Review.
Janssen E, Jukema JW, Beeres SLMA, Schalij MJ, Tops LF
Aims: Major adverse event (MAE) rates during left ventricular assist device (LVAD) therapy in advanced heart failure (HF) patients are high, and impair quality of life and survival. Prediction and risk stratification of MAEs in order to improve patient selection and thereby outcome during LVAD therapy is therefore warranted. Circulating natriuretic peptides (NPs) are strong predictors of MAEs and mortality in chronic HF patients. However, whether NPs can identify patients who are at risk of MAEs...
Abstract
Heart, lung & circulation,
Volume 30, Issue 12, 7 1 2021, Pages e129-e130
Reversal of Femoral Vein Pulsatility Due to Severe Tricuspid Regurgitation After Transcatheter Tricuspid Valve-in-Valve Implantation: A "Wave Dissipation" Effect.
Pereira AR, van der Kley F, Montero-Cabezas JM, de Weger A, Delgado V
Abstract
Cited 17 times since 2021 (4.6 per year)
source: EuropePMC
The Journal of allergy and clinical immunology,
Volume 149, Issue 1, 6 1 2021, Pages 125-134
Unraveling heterogeneity in pediatric atopic dermatitis: Identification of serum biomarker based patient clusters.
Bakker DS, de Graaf M, Nierkens S, Delemarre EM, Knol E, van Wijk F, de Bruin-Weller MS, Drylewicz J, Thijs JL
Background: Increasing evidence shows that pediatric atopic dermatitis (AD) differs from adult AD on a biologic level. Broad biomarker profiling across a wide range of ages of pediatric patients with AD is lacking. Objective: Our aim was to identify serum biomarker profiles in children with AD aged 0 to 17 years and compare these profiles with those previously found in adults with AD. Methods: Luminex multiplex immunoassays were used to measure 145 biomarkers in serum from 240 children with AD (...
Abstract
Cited 7 times since 2021 (1.9 per year)
source: EuropePMC
The American journal of cardiology,
Volume 154, 4 1 2021, Pages 92-98
Prognostic Value of Maximal and Submaximal Exercise Performance in Fontan Patients < 15 Years of Age.
Terol Espinosa de Los Monteros C, Harteveld LM, Kuipers IM, Rammeloo L, Hazekamp MG, Blom NA, Ten Harkel ADJ
In patients after Fontan completion exercise capacity is significantly reduced. Although peak oxygen consumption (VO2peak) is a strong prognostic factor in many cardiovascular diseases, it requires the achievement of a maximal effort. Therefore, submaximal exercise parameters such as oxygen uptake efficiency slope (OUES) may be of value. In the present observational study we evaluated the exercise capacity with maximal and submaximal parameters in a group of Fontan patients with an extracardiac...
Abstract
Cited 1 times since 2021 (0.3 per year)
source: EuropePMC
Complementary therapies in clinical practice,
Volume 44, 4 1 2021, Pages 101437
Effect of reflexology on ankle brachial index, diabetic peripheral neuropathy, and glycemic control in older adults with diabetes: A randomized controlled trial.
Cicek SC, Demir S, Yilmaz D, Yildiz S
Objective: The purpose of this study was to determine the effect of foot reflexology on ankle brachial index, diabetic peripheral neuropathy and glycemic control in older adults with diabetes. Methods: A randomized controlled, parallel-group trial study was conducted at the outpatient elderly health center in Bolu, Turkey. 48 adults aged 65 and over enrolled in the elderly health center were randomized into two groups in a ratio of 1:1 (experimental, n = 24; control, n = 24). Foot reflexology wa...
Abstract
Cited 21 times since 2021 (5.7 per year)
source: EuropePMC
Journal of neurology,
Volume 269, Issue 3, 3 1 2021, Pages 1375-1385
The natural history of primary progressive aphasia: beyond aphasia.
Ulugut H, Stek S, Wagemans LEE, Jutten RJ, Keulen MA, Bouwman FH, Prins ND, Lemstra AW, Krudop W, Teunissen CE, van Berckel BNM, Ossenkoppele R, Barkhof F, van der Flier WM, Scheltens P, Pijnenburg YAL
Introduction: Primary progressive aphasia (PPA) is divided into three prototypical subtypes that are all characterized by their single core symptom of aphasia. Although later in their course, other cognitive, behavioral, and motor domains may become involved, little is known about the progression profile of each subtype relative to the other subtypes. Methods: In this longitudinal retrospective cohort study, based on the recent biomarker-supported diagnostic criteria, 24 subjects diagnosed with...
Abstract
Cited 9 times since 2021 (2.4 per year)
source: EuropePMC
Proceedings of the National Academy of Sciences of the United States of America,
Volume 118, Issue 27, 1 1 2021, Pages e2102026118
Multiscale mechanics and temporal evolution of vimentin intermediate filament networks.
Schepers AV, Lorenz C, Nietmann P, Janshoff A, Klumpp S, Köster S
The cytoskeleton, an intricate network of protein filaments, motor proteins, and cross-linkers, largely determines the mechanical properties of cells. Among the three filamentous components, F-actin, microtubules, and intermediate filaments (IFs), the IF network is by far the most extensible and resilient to stress. We present a multiscale approach to disentangle the three main contributions to vimentin IF network mechanics-single-filament mechanics, filament length, and interactions between fil...
Abstract
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 60, Issue 2, 1 1 2021, Pages 435-436
Prediction is very difficult, especially about the future.
Tomšič A, Klautz RJM
Abstract
Cited 11 times since 2021 (3 per year)
source: EuropePMC
BMJ open gastroenterology,
Volume 8, Issue 1, 1 1 2021, Pages e000670
Quality of life in patients with IBD during the COVID-19 pandemic in the Netherlands.
de Bock E, Filipe MD, Meij V, Oldenburg B, van Schaik FDM, Bastian OW, Fidder HF, Vriens MR, Richir MC
Objective: COVID-19 has put a strain on regular healthcare worldwide. For inflammatory bowel disease (IBD), gastrointestinal surgeries were postponed and changes in treatment and diagnostic procedures were made. As abrupt changes in treatment regimens may result in an increased morbidity and consequent well-being of patients with IBD, the aim of this study was to determine the effect of the COVID-19 pandemic on health-related quality of life (HRQoL) in patients with IBD. Design: All patients wit...
Abstract
Cited 2 times since 2021 (0.5 per year)
source: EuropePMC
Current health sciences journal,
Volume 47, Issue 3, 1 1 2021, Pages 331-337
An Examination of the Relationship between Fear of Coronavirus (COVID-19) in First Year Nursing Students and Their Attitudes to the Profession.
Yilmaz D, Yilmaz DU
This study was conducted with the aim of determining the fear of coronavirus (COVID-19) and attitudes to the profession in first year nursing students, and examining the relationship between them. The descriptive study was conducted in April and May 2021 with first year students at the Nursing Department of Bursa Uludağ University. The research sample consisted of 156 students who participated voluntarily in the study. A Student Description Form, a Coronavirus (COVID-19) Fear Scale and an Attitu...
Abstract
Cited 84 times since 2021 (22.6 per year)
source: EuropePMC
Cell reports,
Volume 36, Issue 4, 1 1 2021, Pages 109441
The Cancer SENESCopedia: A delineation of cancer cell senescence.
Jochems F, Thijssen B, De Conti G, Jansen R, Pogacar Z, Groot K, Wang L, Schepers A, Wang C, Jin H, Beijersbergen RL, Leite de Oliveira R, Wessels LFA, Bernards R
Cellular senescence is characterized as a stable proliferation arrest that can be triggered by multiple stresses. Most knowledge about senescent cells is obtained from studies in primary cells. However, senescence features may be different in cancer cells, since the pathways that are involved in senescence induction are often deregulated in cancer. We report here a comprehensive analysis of the transcriptome and senolytic responses in a panel of 13 cancer cell lines rendered senescent by two dis...
Abstract
Cited 2 times since 2021 (0.5 per year)
source: EuropePMC
Cardiovascular research,
Volume 117, Issue 8, 1 1 2021, Pages 1923-1934
Impaired cytoplasmic domain interactions cause co-assembly defect and loss of function in the p.Glu293Lys KNCJ2 variant isolated from an Andersen-Tawil syndrome patient.
Déri S, Borbás J, Hartai T, Hategan L, Csányi B, Visnyovszki Á, Madácsy T, Maléth J, Hegedűs Z, Nagy I, Arora R, Labro AJ, Környei L, Varró A, Sepp R, Ördög B
Aims: Subunit interactions at the cytoplasmic domain interface (CD-I) have recently been shown to control gating in inward rectifier potassium channels. Here we report the novel KCNJ2 variant p.Glu293Lys that has been found in a patient with Andersen-Tawil syndrome type 1 (ATS1), causing amino acid substitution at the CD-I of the inward rectifier potassium channel subunit Kir2.1. Neither has the role of Glu293 in gating control been investigated nor has a pathogenic variant been described at thi...
Abstract
Balkan medical journal,
Volume 38, Issue 4, 1 1 2021, Pages 222-228
Evaluation of COVID-19 Disease and the Effect of Trends in Intervention Measures: The Pediatric Perspective from a Tertiary Care Hospital in Turkey.
Şık N, Duman M, Yılmaz D, Karaoğlu Asrak H, Erbaş İC, Çakıl Güzin A, Özdem Alataş Ş, Appak Ö, Sayıner AA, Belet N
Background: COVID-19 is an emerging disease of global public health concern. Aims: To evaluate the epidemiological, clinical, laboratory, and radiologic findings and the clinical outcomes of children who were diagnosed with SARS-CoV-2 by polymerase chain reaction (PCR), and to evaluate the effect of the trends in intervention measures. Study design: Between April 2, 2020 and January 16, 2021, children aged 0-18 years who had presented at the pediatric emergency department and were diagnosed with...
Abstract
Cited 440 times since 2021 (118.3 per year)
source: EuropePMC
European heart journal,
Volume 42, Issue 25, 1 1 2021, Pages 2439-2454
SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe.
SCORE2 working group and ESC Cardiovascular risk collaboration
Aims: The aim of this study was to develop, validate, and illustrate an updated prediction model (SCORE2) to estimate 10-year fatal and non-fatal cardiovascular disease (CVD) risk in individuals without previous CVD or diabetes aged 40-69 years in Europe. Methods and results: We derived risk prediction models using individual-participant data from 45 cohorts in 13 countries (677 684 individuals, 30 121 CVD events). We used sex-specific and competing risk-adjusted models, including age, smoking s...
Abstract
Cited 3 times since 2021 (0.8 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 60, Issue 1, 1 1 2021, Pages 7-33
Consensus document on optimal management of patients with common arterial trunk.
Hazekamp MG, Barron DJ, Dangel J, Homfray T, Jongbloed MRM, Voges I, ESC Scientific Document Group
Abstract
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists,
Volume 28, Issue 6, 30 5 2021, Pages 852-859
Functional Performance After Complex Endovascular Aortic Repair: A Single-Center Retrospective Cohort Study.
Warmerdam BWCM, van Holstein Y, Eefting D, van Rijswijk CSP, van der Meer RW, Mooijaart SP, Hamming JF, van der Vorst JR, van Schaik J
Purpose: Complex endovascular aortic repair (EVAR) procedures provide a treatment option for patients with aortic aneurysms involving visceral branches. Good technical results and short-term outcomes have been reported. Whether complex EVAR provides acceptable functional outcomes is not clear. The current study aims to describe postoperative functional outcomes in complex EVAR patients-an older and relatively frail patient group. Materials and methods: A single-center retrospective cohort study...
Abstract
Cited 4 times since 2021 (1.1 per year)
source: EuropePMC
Journal of cellular and molecular medicine,
Volume 25, Issue 16, 30 5 2021, Pages 7772-7782
Phosphorylcholine antibodies restrict infarct size and left ventricular remodelling by attenuating the unreperfused post-ischaemic inflammatory response.
Pluijmert NJ, de Jong RCM, de Vries MR, Pettersson K, Atsma DE, Jukema JW, Quax PHA
Phosphorylcholine is a pro-inflammatory epitope exposed on apoptotic cells, and phosphorylcholine monoclonal immunoglobulin (Ig)G antibodies (PC-mAb) have anti-inflammatory properties. In this study, we hypothesize that PC-mAb treatment reduces adverse cardiac remodelling and infarct size (IS) following unreperfused transmural myocardial infarction (MI). Unreperfused MI was induced by permanent ligation of the left anterior descending (LAD) coronary artery in hypercholesterolaemic APOE*3-Leiden...
Abstract
Cited 12 times since 2021 (3.2 per year)
source: EuropePMC
Radiology,
Volume 300, Issue 3, 29 5 2021, Pages 549-556
Relationship of Endothelial Shear Stress with Plaque Features with Coronary CT Angiography and Vasodilating Capability with PET.
Kalykakis GE, Antonopoulos AS, Pitsargiotis T, Siogkas P, Exarchos T, Kafouris P, Sakelarios A, Liga R, Tzifa A, Giannopoulos A, Scholte AJHA, Kaufmann PA, Parodi O, Knuuti J, Fotiadis DI, Neglia D, Anagnostopoulos CD
Background Advances in three-dimensional reconstruction techniques and computational fluid dynamics of coronary CT angiography (CCTA) data sets make feasible evaluation of endothelial shear stress (ESS) in the vessel wall. Purpose To investigate the relationship between CCTA-derived computational fluid dynamics metrics, anatomic and morphologic characteristics of coronary lesions, and their comparative performance in predicting impaired coronary vasodilating capability assessed by using PET myoc...
Abstract
Cited 5 times since 2021 (1.3 per year)
source: EuropePMC
Thrombosis journal,
Volume 19, Issue 1, 27 4 2021, Pages 45
Differential effect of statin use on coagulation markers: an active comparative analysis in the NEO study.
Bordbar M, de Mutsert R, Cevval M, Rosendaal FR, Jukema JW, Lijfering WM
Background: Statins are a potential treatment for venous thromboembolism (VTE) prophylaxis complementary to conventional anticoagulants without associated bleeding complications. This study aimed to compare pro-thrombotic activities of different classes of lipid-lowering drugs in an active comparator design and determine whether there is a relation between statin versus fibrate/niacin use and pro-coagulant factor outcomes. Methods: This is a cross-sectional analysis of participants from the Neth...
Abstract
