6888 results
Cited 13 times since 2021 (3.2 per year)
source: EuropePMC
Angiogenesis,
Volume 24, Issue 3, 7 1 2021, Pages 567-581
Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization.
Baganha F, de Jong RCM, Peters EA, Voorham W, Jukema JW, Delibegovic M, de Vries MR, Quax PHA
Objective: Statins pleiotropically provide additional benefits in reducing atherosclerosis, but their effects on intraplaque angiogenesis (IPA) and hemorrhage (IPH) remain unclear. Therefore, we discriminated statin's lipid-lowering dependent and independent effects on IPA and IPH. Approach and results: ApoE3*Leiden mice are statin-responsive due to ApoE and LDLR presence, but also allow to titrate plasma cholesterol levels by diet. Therefore, ApoE3*Leiden mice were fed a high-cholesterol-i...
Abstract
Cited 18 times since 2021 (4.4 per year)
source: EuropePMC
International journal of cardiology,
Volume 331, 3 1 2021, Pages 316-321
Standard and emerging CMR methods for mitral regurgitation quantification.
Fidock B, Archer G, Barker N, Elhawaz A, Al-Mohammad A, Rothman A, Hose R, Hall IR, Grech E, Briffa N, Lewis N, van der Geest RJ, Zhang JM, Zhong L, Swift AJ, Wild JM, De Gárate E, Bucciarelli-Ducci C, Bax JJ, Plein S, Myerson S, Garg P
Background: There are several methods to quantify mitral regurgitation (MR) by cardiovascular magnetic resonance (CMR). The interoperability of these methods and their reproducibility remains undetermined. Objective: To determine the agreement and reproducibility of different MR quantification methods by CMR across all aetiologies. Methods: Thirty-five patients with MR were recruited (primary MR = 12, secondary MR = 10 and MVR = 13). Patients underwent CMR, including cines and four-dimensional f...
Abstract
Cited 6 times since 2021 (1.5 per year)
source: EuropePMC
Journal of internal medicine,
Volume 290, Issue 1, 2 1 2021, Pages 141-156
Identification of IgG1 isotype phosphorylcholine antibodies for the treatment of inflammatory cardiovascular diseases.
de Vries MR, Ewing MM, de Jong RCM, MacArthur MR, Karper JC, Peters EAB, Nordzell M, Karabina SAP, Sexton D, Dahlbom I, Bergman A, Mitchell JR, Frostegård J, Kuiper J, Ninio E, Jukema JW, Pettersson K, Quax PHA
Background: Phosphorylcholine (PC) is an important pro-inflammatory damage-associated molecular pattern. Previous data have shown that natural IgM anti-PC protects against cardiovascular disease. We aimed to develop a monoclonal PC IgG antibody with anti-inflammatory and anti-atherosclerotic properties. Methods: Using various techniques PC antibodies were validated and optimized. In vivo testing was performed in a femoral artery cuff model in ApoE3*Leiden mice. Safety studies are performed in ra...
Abstract
Cited 11 times since 2021 (2.7 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 77, Issue 6, 1 1 2021, Pages 761-771
Preventing Arrhythmic Death in Patients With Tetralogy of Fallot: JACC Review Topic of the Week.
Cohen MI, Khairy P, Zeppenfeld K, Van Hare GF, Lakkireddy DR, Triedman JK
Patients with tetralogy of Fallot are at risk for ventricular arrhythmias and sudden cardiac death. These abnormalities are associated with pulmonary regurgitation, right ventricular enlargement, and a substrate of discrete, slowly-conducting isthmuses. Although these arrhythmic events are rare, their prediction is challenging. This review will address contemporary risk assessment and prevention strategies. Numerous variables have been proposed to predict who would benefit from an implantable ca...
Abstract
Cited 3 times since 2021 (0.7 per year)
source: EuropePMC
Pediatric cardiology,
Volume 42, Issue 4, 1 1 2021, Pages 866-874
Oxygen Uptake Efficiency Slope is Strongly Correlated to VO<sub>2peak</sub> Long-Term After Arterial Switch Operation.
Terol Espinosa de Los Monteros C, Van der Palen RLF, Hazekamp MG, Rammeloo L, Jongbloed MRM, Blom NA, Harkel ADJT
After the arterial switch operation (ASO) for transposition of the great arteries (TGA), many patients have an impaired exercise tolerance. Exercise tolerance is determined with cardiopulmonary exercise testing by peak oxygen uptake (VO2peak). Unlike VO2peak, the oxygen uptake efficiency slope (OUES) does not require a maximal effort for interpretation. The value of OUES has not been assessed in a large group of patients after ASO. The purpose of this study was to determine OUES and VO2peak, eva...
Abstract
Cited 6 times since 2021 (1.5 per year)
source: EuropePMC
Tissue engineering. Part C, Methods,
Volume 27, Issue 2, 1 1 2021, Pages 100-114
Advanced <i>In Vitro</i> Modeling to Study the Paradox of Mechanically Induced Cardiac Fibrosis.
Bracco Gartner TCL, Stein JM, Muylaert DEP, Bouten CVC, Doevendans PA, Khademhosseini A, Suyker WJL, Sluijter JPG, Hjortnaes J
In heart failure, cardiac fibrosis is the result of an adverse remodeling process. Collagen is continuously synthesized in the myocardium in an ongoing attempt of the heart to repair itself. The resulting collagen depositions act counterproductively, causing diastolic dysfunction and disturbing electrical conduction. Efforts to treat cardiac fibrosis specifically have not been successful and the molecular etiology is only partially understood. The differentiation of quiescent cardiac fibroblasts...
Abstract
Cited 751 times since 2021 (181.9 per year)
source: EuropePMC
European heart journal,
Volume 42, Issue 6, 1 1 2021, Pages 563-645
2020 ESC Guidelines for the management of adult congenital heart disease.
Baumgartner H, De Backer J, Babu-Narayan SV, Budts W, Chessa M, Diller GP, Lung B, Kluin J, Lang IM, Meijboom F, Moons P, Mulder BJM, Oechslin E, Roos-Hesselink JW, Schwerzmann M, Sondergaard L, Zeppenfeld K, ESC Scientific Document Group
Abstract
Pediatric emergency care,
Volume 37, Issue 2, 1 1 2021, Pages e77-e78
Unexpected Diagnosis in an Adolescent With Bruises and Ecchymosis: Celiac Disease.
Er A, Çağlar A, Kuyum P, Akgül F, Ulusoy E, Çitlenbik H, Aksoy BY, Yilmaz D, Arslan N, Duman M
Abstract: Acquired coagulopathy is a rare but challenging diagnosis for pediatric emergency physicians. Although the coagulopathy usually presents with mild skin and mucosal hemorrhages, it also can lead to life-threatening events. Thus, accurate interpretation of hints obtained from a detailed history, physical examination, and laboratory findings is essential for the prompt diagnosis and management. This case demonstrates an uncommon cause of coagulopathy; celiac disease that presented with sp...
Abstract
Cited 5 times since 2021 (1.2 per year)
source: EuropePMC
Journal of thoracic disease,
Volume 13, Issue 2, 1 1 2021, Pages 592-599
Quality assessment of robot assisted thoracic surgical resection of non-small cell lung cancer: nodal upstaging and mediastinal recurrence.
Shahin GM, Topal B, Pouwels S, Markou TL, Boon R, Stigt JA
Background: Robot assisted thoracic surgery (RATS) is the minimally invasive surgical technique of choice for treatment of patients with non-small cell lung cancer (NSCLC), at the Isala Hospital. The aim of this study is to compare clinical and pathological staging results and mediastinal recurrence after RATS for anatomical resections of lung cancer as surrogate markers for quality of mediastinal lymph node dissection (MLND). Methods: This single institute retrospective study was conducted in p...
Abstract
Cited 16 times since 2021 (3.9 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 22, Issue 3, 1 1 2021, Pages 339-347
Left ventricular myocardial work in the culprit vessel territory and impact on left ventricular remodelling in patients with ST-segment elevation myocardial infarction after primary percutaneous coronary intervention.
Lustosa RP, Fortuni F, van der Bijl P, Goedemans L, El Mahdiui M, Montero-Cabezas JM, Kostyukevich MV, Ajmone Marsan N, Bax JJ, Delgado V, Knuuti J
Aims: Adverse left ventricular (LV) remodelling after ST-segment elevation myocardial infarction (STEMI) is associated with poor outcome. Global and regional LV myocardial work (LVMW) derived from speckle tracking echocardiographic strain data in combination with non-invasive blood pressure recordings could provide information for prediction of LV remodelling after STEMI. The aim of the study was to assess the predictive value of global and regional LVMW for LV remodelling before discharge in pa...
Abstract
Cited 8 times since 2021 (1.9 per year)
source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions,
Volume 98, Issue 5, 1 1 2021, Pages E733-E736
Virtual support for remote proctoring in TAVR during COVID-19.
Arslan F, Gerckens U
Objectives: The current report describes a single operator's experience of the first use of smartglass technology as a facilitator of virtual support during TAVR proctoring. Background: Restricted gatherings and containment measures during the ongoing COVID-19 pandemic have a major impact on daily clinical practice. Interaction between peers is crucial in science, clinical practice, and education. In addition, there is also a growing importance of proctoring in interventional cardiology for...
Abstract
Cited 26 times since 2021 (6.3 per year)
source: EuropePMC
The Journal of infectious diseases,
Volume 223, Issue 2, 1 1 2021, Pages 238-246
Associations of Cytomegalovirus Infection With All-Cause and Cardiovascular Mortality in Multiple Observational Cohort Studies of Older Adults.
Chen S, Pawelec G, Trompet S, Goldeck D, Mortensen LH, Slagboom PE, Christensen K, Gussekloo J, Kearney P, Buckley BM, Ford I, Jukema JW, Westendorp RGJ, Maier AB
Background: Whether latent cytomegalovirus (CMV) infection in older adults has any substantial health consequences is unclear. Here, we sought associations between CMV-seropositivity and IgG titer with all-cause and cardiovascular mortality in 5 longitudinal cohorts. Methods: Leiden Longevity Study, Prospective Study of Pravastatin in the Elderly at Risk, Longitudinal Study of Aging Danish Twins, and Leiden 85-plus Study were assessed at median (2.8-11.4 years) follow-up . Cox regression and ran...
Abstract
Cited 3835 times since 2021 (928.8 per year)
source: EuropePMC
European heart journal,
Volume 42, Issue 5, 1 1 2021, Pages 373-498
2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS): The Task Force for the diagnosis and management of atrial fibrillation of the European Society of Cardiology (ESC) Developed with the special contribution of the European Heart Rhythm Association (EHRA) of the ESC.
Hindricks G, Potpara T, Dagres N, Arbelo E, Bax JJ, Blomström-Lundqvist C, Boriani G, Castella M, Dan GA, Dilaveris PE, Fauchier L, Filippatos G, Kalman JM, La Meir M, Lane DA, Lebeau JP, Lettino M, Lip GYH, Pinto FJ, Thomas GN, Valgimigli M, Van Gelder IC, Van Putte BP, Watkins CL, ESC Scientific Document Group
Abstract
Cited 6 times since 2021 (1.5 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 28, Issue 3, 31 5 2021, Pages 1105-1116
Assessing myocardial perfusion in suspected coronary artery disease: rationale and design of the second phase 3, open-label multi-center study of flurpiridaz (F-18) injection for positron emission tomography (PET) imaging.
Bourque JM, Hanson CA, Agostini D, Bateman TM, Bax JJ, Beanlands RSB, Berman DS, Garcia EV, Heller GV, Knuuti J, Tamaki N, Udelson JE, Maddahi J
Background: Positron emission tomography (PET) myocardial perfusion imaging (MPI) with the novel radiopharmaceutical Fluorine-18 Flurpiridaz has been shown in Phase 1, 2, and first Phase 3 clinical studies to be safe and effective in diagnosing coronary artery disease (CAD). We describe the methodology of the second FDA-mandated phase 3 prospective, open-label, international, multi-center trial of F-18 Flurpiridaz PET MPI. Methods: The primary study end point is to assess the diagnostic efficacy...
Abstract
Cited 33 times since 2021 (8 per year)
source: Scopus
EClinicalMedicine,
Volume 32, 28 4 2021, Pages 100731
Short-term outpatient follow-up of COVID-19 patients: A multidisciplinary approach.
de Graaf MA, Antoni ML, Ter Kuile MM, Arbous MS, Duinisveld AJF, Feltkamp MCW, Groeneveld GH, Hinnen SCH, Janssen VR, Lijfering WM, Omara S, Postmus PE, Ramai SRS, Rius-Ottenheim N, Schalij MJ, Schiemanck SK, Smid L, Stöger JL, Visser LG, de Vries JJC, Wijngaarden MA, Geelhoed JJM, Roukens AHE
Background: Short-term follow-up of COVID-19 patients reveals pulmonary dysfunction, myocardial damage and severe psychological distress. Little is known of the burden of these sequelae, and there are no clear recommendations for follow-up of COVID-19 patients.In this multi-disciplinary evaluation, cardiopulmonary function and psychological impairment after hospitalization for COVID-19 are mapped. Methods: We evaluated patients at our outpatient clinic 6 weeks after discharge. Cardiopulmonary fu...
Abstract
The international journal of cardiovascular imaging,
Volume 37, Issue 5, 27 4 2021, Pages 1563-1565
Pacemaker lead-induced tricuspid regurgitation: consider leaflet remodeling.
Fortuni F, van der Kley F, Delgado V, Ajmone Marsan N
Abstract
Cited 16 times since 2021 (3.9 per year)
source: EuropePMC
Journal of cardiovascular development and disease,
Volume 8, Issue 2, 27 4 2021, Pages 12
A Systematic Histopathologic Evaluation of Type-A Aortic Dissections Implies a Uniform Multiple-Hit Causation.
Grewal N, Velders BJJ, Gittenberger-de Groot AC, Poelmann R, Klautz RJM, Van Brakel TJ, Lindeman JHN
(1) Background: The pathophysiologic basis of an acute type A aortic dissection (TAAD) is largely unknown. In an effort to evaluate vessel wall defects, we systematically studied aortic specimens in TAAD patients. (2) Methods: Ascending aortic wall specimens (n = 58, mean age 63 years) with TAAD were collected. Autopsy tissues (n = 17, mean age 63 years) served as controls. All sections were studied histopathologically. (3) Results: Pathomorphology in TAAD showed predominantly moderate elastic f...
Abstract
Cited 16 times since 2021 (3.8 per year)
source: EuropePMC
Appetite,
Volume 161, 22 4 2021, Pages 105135
Healthy eating beliefs and the meaning of food in populations with a low socioeconomic position: A scoping review.
van der Heijden A, Te Molder H, Jager G, Mulder BC
Profound understanding of healthy eating beliefs in populations with a low socioeconomic position (SEP) can benefit attempts to improve diet quality in this population, but literature on this subject is fragmented. The purpose of this scoping review was to systematically map healthy eating beliefs and the meaning of food and eating in populations with a low SEP. Systematic search of electronic databases yielded 35 relevant publications that were included in a qualitative synthesis. Populations w...
Abstract
Cited 1 times since 2021 (0.2 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 29, Issue 4, 20 3 2021, Pages 1534-1536
Diastolic dyssynchrony by SPECT: A novel parameter to predict post-infarct adverse remodeling.
van der Bijl P, Delgado V, Bax JJ
Abstract
Cited 12 times since 2021 (2.9 per year)
source: EuropePMC
Circulation,
Volume 143, Issue 3, 19 3 2021, Pages 209-211
Changing the Paradigm in the Management of Valvular Heart Disease: In Addition to Left Ventricular Ejection Fraction, Focus on the Myocardium.
Fortuni F, Bax JJ, Delgado V
Abstract
