9618 results
Cited 2 times since 2024 (2.2 per year)
source: EuropePMC
Heart & lung : the journal of critical care,
Volume 69, 17 3 2024, Pages 31-39
Modifiable risk factors and motivation for lifestyle change of CVD patients starting cardiac rehabilitation: The BENEFIT study.
Breeman LD, Pérez-Alonso A, Kühling-Romero D, Kraaijenhagen RA, Al-Dhahir I, IJzerman RVH, van Eersel R, Wolstencroft K, Bonten TN, Atsma DE, Chavannes NH, van Gemert-Pijnen L, Kemps HMC, Scholte Op Reimer W, Evers AWM, Janssen VR, BENEFIT consortium
Background: To improve lifestyle guidance within cardiac rehabilitation (CR), a comprehensive understanding of the motivation and lifestyle-supporting needs of patients with cardiovascular disease (CVD) is required. Objectives: This study's purpose is to evaluate patients' lifestyle and their motivation, self-efficacy and social support for change when starting CR. Methods: 1782 CVD patients (69 % male, mean age 62 years) from 7 Dutch outpatient CR centers participated between 2020 and...
Abstract
Research and practice in thrombosis and haemostasis,
Volume 8, Issue 7, 16 3 2024, Pages 102573
The impact of pulmonary embolism on health outcomes of COVID-19 at 3 months after hospitalization.
Visser C, Berentschot JC, de Jong CMM, Antoni ML, Bek LM, van den Berg-Emons RJG, van den Borst B, Ten Cate H, Ten Cate-Hoek AJ, Braeken DCW, Geelhoed JJM, Heijenbrok-Kal MH, van Kuijk SMJ, Kroft LJM, Leentjens J, Roukens AHE, Cannegieter SC, Klok FA, Kruip MJHA, Hellemons ME, Dutch COVID & Thrombosis Coalition@CovidDutch
Background: COVID-19 patients frequently experience pulmonary embolism (PE), but its long-term consequences remain uncertain. Objectives: To assess the impact of PE in COVID-19 patients on health outcomes at 3 months after hospitalization. Methods: In this multicenter cross-sectional study, we aggregated data from existing databases to evaluate the impact of PE on health outcomes at 3 months after hospitalization. We assessed 1) questionnaires on health-related quality of life (5-level EuroQol 5...
Abstract
Cited 15 times since 2024 (16.3 per year)
source: EuropePMC
Nature medicine,
Volume 30, Issue 11, 16 3 2024, Pages 3223-3235
Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial.
Nederlof I, Isaeva OI, de Graaf M, Gielen RCAM, Bakker NAM, Rolfes AL, Garner H, Boeckx B, Traets JJH, Mandjes IAM, de Maaker M, van Brussel T, Chelushkin M, Champanhet E, Lopez-Yurda M, van de Vijver K, van den Berg JG, Hofland I, Klioueva N, Mann RM, Loo CE, van Duijnhoven FH, Skinner V, Luykx S, Kerver E, Kalashnikova E, van Dongen MGJ, Sonke GS, Linn SC, Blank CU, de Visser KE, Salgado R, Wessels LFA, Drukker CA, Schumacher TN, Horlings HM, Lambrechts D, Kok M
Immune checkpoint inhibition (ICI) with chemotherapy is now the standard of care for stage II-III triple-negative breast cancer; however, it is largely unknown for which patients ICI without chemotherapy could be an option and what the benefit of combination ICI could be. The adaptive BELLINI trial explored whether short combination ICI induces immune activation (primary end point, twofold increase in CD8+ T cells or IFNG), providing a rationale for neoadjuvant ICI without chemotherapy. Here, in...
Abstract
Cited 2 times since 2024 (2.2 per year)
source: EuropePMC
Nature communications,
Volume 15, Issue 1, 16 3 2024, Pages 8117
ENCORE: a practical implementation to improve reproducibility and transparency of computational research.
van Kampen AHC, Mahamune U, Jongejan A, van Schaik BDC, Balashova D, Lashgari D, Pras-Raves M, Wever EJM, Dane AD, García-Valiente R, Moerland PD
Reproducibility of computational research is often challenging despite established guidelines and best practices. Translating these guidelines into practical applications remains difficult. Here, we present ENCORE, an approach to enhance transparency and reproducibility by guiding researchers in how to structure and document a computational project. ENCORE builds on previous efforts in computational reproducibility and integrates all project components into a standardized file system structure....
Abstract
Cited 7 times since 2024 (7.5 per year)
source: EuropePMC
Communications biology,
Volume 7, Issue 1, 13 2 2024, Pages 1135
Nucleolus and centromere Tyramide Signal Amplification-Seq reveals variable localization of heterochromatin in different cell types.
Kumar P, Gholamalamdari O, Zhang Y, Zhang L, Vertii A, van Schaik T, Peric-Hupkes D, Sasaki T, Gilbert DM, van Steensel B, Ma J, Kaufman PD, Belmont AS
Genome differential positioning within interphase nuclei remains poorly explored. We extended and validated Tyramide Signal Amplification (TSA)-seq to map genomic regions near nucleoli and pericentric heterochromatin in four human cell lines. Our study confirmed that smaller chromosomes localize closer to nucleoli but further deconvolved this by revealing a preference for chromosome arms below 36-46 Mbp in length. We identified two lamina associated domain subsets through their differential nucl...
Abstract
Cited 8 times since 2024 (8.6 per year)
source: EuropePMC
Clinical chemistry and laboratory medicine,
Volume 62, Issue 12, 13 2 2024, Pages 2373-2387
A vision to the future: value-based laboratory medicine.
Plebani M, Cadamuro J, Vermeersch P, Jovičić S, Ozben T, Trenti T, McMillan B, Lowe CR, Lennerz J, Macintyre E, Gabelli C, Sandberg S, Padoan A, Wiencek JR, Banfi G, Lubin IM, Orth M, Carobene A, Zima T, Cobbaert CM, van Schaik RHN, Lippi G
The ultimate goal of value-based laboratory medicine is maximizing the effectiveness of laboratory tests in improving patient outcomes, optimizing resources and minimizing unnecessary costs. This approach abandons the oversimplified notion of test volume and cost, in favor of emphasizing the clinical utility and quality of diagnostic tests in the clinical decision-making. Several key elements characterize value-based laboratory medicine, which can be summarized in some basic concepts, such as or...
Abstract
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery,
Volume 68, Issue 6, 11 2 2024, Pages 815-816
Editor's Choice - Radiation Protection and Pregnancy in Vascular Surgery and Interventional Radiology in the Netherlands.
Jongen JMJ, Samim M, Hoornstra KJPC, Eefting D, van Herwaarden JA, Blok JJ
Abstract
Preventive veterinary medicine,
Volume 233, 11 2 2024, Pages 106334
Evaluation of a voluntary passive surveillance component in cattle through notification of excess mortality.
Vredenberg I, van Schaik G, van der Poel WHM, Stegeman A
Passive surveillance can be most effective in the early detection of disease outbreaks given that farmers observe their animals daily. The European Animal Health Law states that unexplained excess mortality should be reported to the veterinary authorities. In the Netherlands, in addition to notifications to the competent authority, Royal GD is commissioned a passive surveillance component that consists of a veterinary helpdesk and postmortem examination for early detection of emerging diseases....
Abstract
Cited 1 times since 2024 (1.1 per year)
source: EuropePMC
Frontiers in medicine,
Volume 11, 11 2 2024, Pages 1443291
The "angioletti" of Palermo: the health and development of mummified non-adults in late modern Palermo, Sicily (1787-1880 CE).
Squires K, Viner M, Hoban W, Loynes R, Van Schaik K, Piombino-Mascali D
The Capuchin Catacombs in Palermo, Sicily, have been home to non-adult mummified remains since the seventeenth century CE. Despite the increasing numbers of scientific studies conducted at this site, very little research has focused specifically on the youngest members of late modern (1787-1880 CE) society. This research aims to redress the balance by examining 43 individuals to gain insight into the demographic profile of mummified non-adults, to characterize their health status and possible ca...
Abstract
Cited 3 times since 2024 (3.2 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 32, Issue 10, 10 2 2024, Pages 338-345
2023 European Society of Cardiology guidelines for the management of acute coronary syndromes : Statement of endorsement by the NVVC.
Zwart B, Claessen BEPM, Damman P, Woudstra P, Vink MA, Balder JW, Dickinson MG, Badings EA, Appelman Y, van 't Hof AWJ, Ten Berg JM, Arslan F
This review discusses the new recommendations in the 2023 European Society of Cardiology guidelines on the management of acute coronary syndrome and provides a perspective on topics specific to clinical practice in the Netherlands, including pre-treatment, antiplatelet agent strategies, the use of risk scores and logistical considerations with regard to the timing of coronary angiography.
Abstract
Cited 4 times since 2024 (4.2 per year)
source: EuropePMC
Atherosclerosis,
Volume 398, 7 1 2024, Pages 118595
Arterial inflammation on [<sup>18</sup>F]FDG PET/CT in melanoma patients treated with and without immune checkpoint inhibitors: CHECK-FLAME I.
Polomski EAS, Kapiteijn EW, Heemelaar JC, van der Kolk AV, Kalisvaart TM, van de Burgt A, Dibbets-Schneider P, van Velden FHP, Seijkens TTP, Stöger JL, Jukema JW, de Geus-Oei LF, Antoni ML
Background and aims: Immune checkpoint inhibitors (ICIs) revolutionized cancer treatment. However, ICIs may increase the immune response to non-tumor cells, possibly resulting in increased arterial inflammation, raising the risk of atherosclerotic events. Nevertheless, malignancies may induce a pro-inflammatory state and the association between ICIs and arterial inflammation remains to be clarified. This study aims to assess differences in increase in arterial inflammation between patients with...
Abstract
Heart rhythm,
Volume 22, Issue 6, 6 1 2024, Pages 1384-1393
Lesion delivery and scar formation in catheter ablation for atrial fibrillation: The DECAAF II trial.
Akoum N, Mekhael M, Bisbal F, Wazni O, McGann C, Lee H, Bardsley T, Greene T, Dean JM, Dagher L, Kholmovski E, Mansour M, Marchlinski F, Wilber D, Hindricks G, Mahnkopf C, Wells D, Jaïs P, Sanders P, Brachmann J, Bax JJ, Morrison-de Boer L, Deneke T, Calkins H, Sohns C, Marrouche N, DECAAF II investigators
Background: The Efficacy of Delayed Enhancement MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation of Atrial Fibrillation randomized trial showed no difference in atrial fibrillation (AF) recurrence with additional delayed enhancement magnetic resonance imaging (DE-MRI) fibrosis-targeted ablation to pulmonary vein isolation (PVI) in persistent AF. Objective: We evaluated the effect of lesion delivery on ablation-induced scarring and AF recurrence. Methods: Lesions delivered, targetin...
Abstract
Frontiers in neuroscience,
Volume 18, 6 1 2024, Pages 1450640
Memory-efficient neurons and synapses for spike-timing-dependent-plasticity in large-scale spiking networks.
Urbizagastegui P, van Schaik A, Wang R
This paper addresses the challenges posed by frequent memory access during simulations of large-scale spiking neural networks involving synaptic plasticity. We focus on the memory accesses performed during a common synaptic plasticity rule since this can be a significant factor limiting the efficiency of the simulations. We propose neuron models that are represented by only three state variables, which are engineered to enforce the appropriate neuronal dynamics. Additionally, memory retrieval is...
Abstract
Cited 1 times since 2024 (1 per year)
source: EuropePMC
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists,
5 1 2024, Pages 15266028241274568
Maximal Systolic Acceleration and Near-Infrared Fluorescence Imaging With Indocyanine Green as Predictors for Successful Lower Extremity Revascularization.
Kruiswijk MW, Willems SA, Koning S, Tange FP, J W M Brouwers J, Peul RC, van Schaik J, Schepers A, Hamming J, van der Bogt KEA, van Rijswijk CSP, Vahrmeijer AL, van den Hoven P, van der Vorst JR
Background: Patients with lower extremity arterial disease (LEAD) frequently require revascularization procedures. Currently used diagnostic methods are insufficient in predicting successful outcomes and focus on macrovascular rather than microvascular state. Several promising modalities to increase diagnostic accuracy are emerging, including maximal systolic acceleration (ACCmax), measured by duplex ultrasound (DUS). For the assessment of tissue perfusion, near-infrared fluorescence (NIR) imagi...
Abstract
The Pediatric infectious disease journal,
Volume 44, Issue 1, 4 1 2024, Pages 83-89
Pediatric Varicella-related Hospitalization in Turkey Between 2008 and 2018: Impact of Universal Single Dose Varicella Vaccine (VARICOMP Study).
Dinleyici EC, Kurugol Z, Devrim I, Bayram N, Dalgic N, Yasa O, Tezer H, Ozdemir H, Ciftci E, Tapisiz A, Celebi S, Hacimustafaoglu M, Yilmaz D, Hatipoglu N, Kara A, VARICOMP Study Group
Background: A single-dose varicella vaccine at 12 months of age was introduced to the National Immunization Program in February 2013 in Turkey. This study aimed to evaluate varicella-related hospitalization in children and the impact of a single-dose live attenuated varicella vaccine over the first 5.5 years of introducing a universal varicella vaccination. Methods: We analyzed data collected from the medical records of children
Abstract
Cited 1 times since 2024 (1 per year)
source: EuropePMC
American heart journal,
Volume 278, 2 1 2024, Pages 61-71
Low-dose colchicine for the prevention of cardiovascular events after percutaneous coronary intervention: Rationale and design of the COL BE PCI trial.
De Cock E, Kautbally S, Timmermans F, Bogaerts K, Hanet C, Desmet W, Gurné O, Vranckx P, Hiltrop N, Dujardin K, Vanduynhoven P, Vermeersch P, Pirlet C, Hermans K, Van Reet B, Ferdinande B, Aminian A, Dewilde W, Guédès A, Simon F, De Roeck F, De Vroey F, Jukema JW, Sinnaeve P, Buysschaert I
Introduction: Patients with coronary artery disease (CAD) remain vulnerable to future major atherosclerotic events after revascularization, despite effective secondary prevention strategies. Inflammation plays a central role in the pathogenesis of CAD and recurrent events. To date, there is no specific anti-inflammatory medicine available with proven effective, cost-efficient, and favorable benefit-risk profile, except for colchicine. Initial studies with colchicine have sparked major interest i...
Abstract
Cited 8 times since 2024 (8.3 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 84, Issue 13, 1 1 2024, Pages 1178-1189
Temporal Trends in Takotsubo Syndrome: Results From the International Takotsubo Registry.
Schweiger V, Cammann VL, Crisci G, Gilhofer T, Schlenker R, Niederseer D, Chen S, Ebrahimi R, Wenzl F, Würdinger M, Citro R, Vecchione C, Gili S, Neuhaus M, Franke J, Meder B, Jaguszewski M, Noutsias M, Knorr M, Jansen T, D'Ascenzo F, Dichtl W, von Lewinski D, Burgdorf C, Kherad B, Tschöpe C, Sarcon A, Shinbane J, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Karakas M, Koenig W, Pott A, Meyer P, Roffi M, Banning A, Wolfrum M, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Napp LC, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Chan C, Bridgman P, Beug D, Delmas C, Lairez O, Gilyarova E, Shilova A, Gilyarov M, El-Battrawy I, Akin I, Poledniková K, Toušek P, Winchester DE, Massoomi M, Galuszka J, Ukena C, Poglajen G, Carrilho-Ferreira P, Hauck C, Paolini C, Bilato C, Kobayashi Y, Kato K, Ishibashi I, Himi T, Din J, Al-Shammari A, Prasad A, Rihal CS, Liu K, Schulze PC, Bianco M, Jörg L, Rickli H, Pestana G, Nguyen TH, Böhm M, Maier LS, Pinto FJ, Widimský P, Felix SB, Braun-Dul
Background: The perception of takotsubo syndrome (TTS) has evolved significantly over the years, primarily driven by increased recognition of acute complications and mortality. Objectives: This study aimed to explore temporal trends in demographic patterns, risk factors, clinical presentations, and outcomes in patients with TTS. Methods: Patients diagnosed with TTS between 2004 and 2021 were enrolled from the InterTAK (International Takotsubo) registry. To assess temporal trends, patients were d...
Abstract
Cited 6 times since 2024 (6.2 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 84, Issue 11, 1 1 2024, Pages 994-1006
Triglyceride Levels, Alirocumab Treatment, and Cardiovascular Outcomes After an Acute Coronary Syndrome.
Zahger D, Schwartz GG, Du W, Szarek M, Bhatt DL, Bittner VA, Budaj AJ, Diaz R, Goodman SG, Jukema JW, Kiss RG, Harrington RA, Moriarty PM, Scemama M, Manvelian G, Pordy R, White HD, Zeiher AM, Fazio S, Geba GP, Steg PG, ODYSSEY OUTCOMES Investigators
Background: It is unknown whether clinical benefit of proprotein convertase subtilisin/kexin type 9 inhibitors is associated with baseline or on-treatment triglyceride concentrations. Objectives: This study sought to examine relations between triglyceride levels and the effect of alirocumab vs placebo on cardiovascular outcomes using prespecified and post hoc analyses of the ODYSSEY OUTCOMES (Evaluation of Cardiovascular Outcomes After an Acute Coronary Syndrome During Treatment With Alirocumab)...
Abstract
Cited 1 times since 2024 (1 per year)
source: EuropePMC
Clinical cancer research : an official journal of the American Association for Cancer Research,
Volume 30, Issue 18, 1 1 2024, Pages 4227-4239
Platinum-Based Chemotherapy Induces Opposing Effects on Immunotherapy Response-Related Spatial and Stromal Biomarkers in the Bladder Cancer Microenvironment.
Chelushkin MA, van Dorp J, van Wilpe S, Seignette IM, Mellema JJ, Alkemade M, Gil-Jimenez A, Peters D, Brugman W, Stockem CF, Hooijberg E, Broeks A, van Rhijn BWG, Mertens LS, van der Heijden AG, Mehra N, van Montfoort ML, Wessels LFA, Vis DJ, van der Heijden MS
Purpose: Platinum-based chemotherapy and immune checkpoint inhibitors are key components of systemic treatment for muscle-invasive and advanced urothelial cancer. The ideal integration of these two treatment modalities remains unclear as clinical trials have led to inconsistent results. Modulation of the tumor-immune microenvironment by chemotherapy is poorly characterized. We aimed to investigate this modulation, focusing on potential clinical implications for immune checkpoint inhibitor respon...
Abstract
Cited 8 times since 2024 (8.3 per year)
source: EuropePMC
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin,
Volume 29, Issue 39, 1 1 2024
Increased circulation of GII.17 noroviruses, six European countries and the United States, 2023 to 2024.
Chhabra P, Wong S, Niendorf S, Lederer I, Vennema H, Faber M, Nisavanh A, Jacobsen S, Williams R, Colgan A, Yandle Z, Garvey P, Al-Hello H, Ambert-Balay K, Barclay L, de Graaf M, Celma C, Breuer J, Vinjé J, Douglas A
We report an increase in GII.17 norovirus outbreaks and sporadic infections of acute gastroenteritis in Austria, Germany, France, Ireland, the Netherlands, England and the United States during the 2023/24 season. A decrease in GII.4 coincided with GII.17 prevalence increasing to between 17% and 64% of all GII detections. Overall, 84% of the GII.17 strains clustered closely with strains first reported in Romania in 2021 and two new sub-lineages were identified. Norovirus surveillance and molecula...
Abstract
