Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
9618 results
Cited 2 times since 2024 (2.1 per year) source: EuropePMC
Neural computation, Volume 36, Issue 10, 1 1 2024, Pages 1939-2029 Electrical Signaling Beyond Neurons. Monk T, Dennler N, Ralph N, Rastogi S, Afshar S, Urbizagastegui P, Jarvis R, van Schaik A, Adamatzky A
Neural action potentials (APs) are difficult to interpret as signal encoders and/or computational primitives. Their relationships with stimuli and behaviors are obscured by the staggering complexity of nervous systems themselves. We can reduce this complexity by observing that "simpler" neuron-less organisms also transduce stimuli into transient electrical pulses that affect their behaviors. Without a complicated nervous system, APs are often easier to understand as signal/response mec... Abstract
Cited 9 times since 2024 (9.3 per year) source: EuropePMC
European heart journal. Cardiovascular Imaging, Volume 25, Issue 10, 1 1 2024, Pages 1351-1359 Pericoronary adipose tissue for predicting long-term outcomes. van Rosendael SE, Kamperidis V, Maaniitty T, de Graaf MA, Saraste A, McKay-Goodall GE, Jukema JW, Knuuti J, Bax JJ
Aims: Pericoronary adipose tissue (PCAT) attenuation obtained by coronary computed tomography angiography (CCTA) has been associated with coronary inflammation and outcomes. Whether PCAT attenuation is predictive of major adverse cardiac events (MACE) during long-term follow-up is unknown. Methods and results: Symptomatic patients with coronary artery disease (CAD) who underwent CCTA were included, and clinical outcomes were evaluated. PCAT was measured at all lesions for all three major coronar... Abstract
Cited 1 times since 2024 (1 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 37, Issue 12, 1 1 2024, Pages 1188-1190.e3 Right Ventricular to Pulmonary Artery Coupling and Prognosis in Transthyretin Cardiac Amyloidosis. Meucci MC, Laenens D, Lillo R, Lombardo A, Burzotta F, Stassen J, Debonnaire P, Claeys M, Donal E, Droogmans S, Cosyns B, Jurcut R, Pinto FJ, Brito D, Yedidya I, Van De Heyning C, Sturkenboom N, Graziani F, Ajmone Marsan N
Cited 186 times since 2024 (193 per year) source: EuropePMC
European heart journal, Volume 45, Issue 36, 1 1 2024, Pages 3538-3700 2024 ESC Guidelines for the management of peripheral arterial and aortic diseases. Mazzolai L, Teixido-Tura G, Lanzi S, Boc V, Bossone E, Brodmann M, Bura-Rivière A, De Backer J, Deglise S, Della Corte A, Heiss C, Kałużna-Oleksy M, Kurpas D, McEniery CM, Mirault T, Pasquet AA, Pitcher A, Schaubroeck HAI, Schlager O, Sirnes PA, Sprynger MG, Stabile E, Steinbach F, Thielmann M, van Kimmenade RRJ, Venermo M, Rodriguez-Palomares JF, ESC Scientific Document Group
Cited 586 times since 2024 (608.1 per year) source: EuropePMC
European heart journal, Volume 45, Issue 36, 1 1 2024, Pages 3415-3537 2024 ESC Guidelines for the management of chronic coronary syndromes. Vrints C, Andreotti F, Koskinas KC, Rossello X, Adamo M, Ainslie J, Banning AP, Budaj A, Buechel RR, Chiariello GA, Chieffo A, Christodorescu RM, Deaton C, Doenst T, Jones HW, Kunadian V, Mehilli J, Milojevic M, Piek JJ, Pugliese F, Rubboli A, Semb AG, Senior R, Ten Berg JM, Van Belle E, Van Craenenbroeck EM, Vidal-Perez R, Winther S, ESC Scientific Document Group
Cited 638 times since 2024 (662.1 per year) source: EuropePMC
European heart journal, Volume 45, Issue 36, 1 1 2024, Pages 3314-3414 2024 ESC Guidelines for the management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). Van Gelder IC, Rienstra M, Bunting KV, Casado-Arroyo R, Caso V, Crijns HJGM, De Potter TJR, Dwight J, Guasti L, Hanke T, Jaarsma T, Lettino M, Løchen ML, Lumbers RT, Maesen B, Mølgaard I, Rosano GMC, Sanders P, Schnabel RB, Suwalski P, Svennberg E, Tamargo J, Tica O, Traykov V, Tzeis S, Kotecha D, ESC Scientific Document Group
Cited 10 times since 2024 (10.3 per year) source: EuropePMC
The New England journal of medicine, Volume 392, Issue 5, 31 5 2024, Pages 438-449 Continuation versus Interruption of Oral Anticoagulation during TAVI. van Ginkel DJ, Bor WL, Aarts HM, Dubois C, De Backer O, Rooijakkers MJP, Rosseel L, Veenstra L, van der Kley F, van Bergeijk KH, Van Mieghem NM, Agostoni P, Voskuil M, Schotborgh CE, IJsselmuiden AJJ, Van Der Heyden JAS, Hermanides RS, Barbato E, Mylotte D, Fabris E, Frambach P, Dujardin K, Ferdinande B, Peper J, Rensing BJWM, Timmers L, Swaans MJ, Brouwer J, Nijenhuis VJ, Overduin DC, Adriaenssens T, Kobari Y, Vriesendorp PA, Montero-Cabezas JM, El Jattari H, Halim J, Van den Branden BJL, Leonora R, Vanderheyden M, Lauterbach M, Wykrzykowska JJ, van 't Hof AWJ, van Royen N, Tijssen JGP, Delewi R, Ten Berg JM, POPular PAUSE TAVI Investigators, POPular PAUSE TAVI Investigators
Background: One third of patients undergoing transcatheter aortic-valve implantation (TAVI) have an indication for oral anticoagulation owing to concomitant diseases. Interruption of oral anticoagulation during TAVI may decrease the risk of bleeding, whereas continuation may decrease the risk of thromboembolism. Methods: We conducted an international, open-label, randomized, noninferiority trial involving patients who were receiving oral anticoagulants and were planning to undergo TAVI. Patients... Abstract
Cited 2 times since 2024 (2.1 per year) source: EuropePMC
Nature communications, Volume 15, Issue 1, 30 5 2024, Pages 7551 Time-series sewage metagenomics distinguishes seasonal, human-derived and environmental microbial communities potentially allowing source-attributed surveillance. Becsei Á, Fuschi A, Otani S, Kant R, Weinstein I, Alba P, Stéger J, Visontai D, Brinch C, de Graaf M, Schapendonk CME, Battisti A, De Cesare A, Oliveri C, Troja F, Sironen T, Vapalahti O, Pasquali F, Bányai K, Makó M, Pollner P, Merlotti A, Koopmans M, Csabai I, Remondini D, Aarestrup FM, Munk P
Sewage metagenomics has risen to prominence in urban population surveillance of pathogens and antimicrobial resistance (AMR). Unknown species with similarity to known genomes cause database bias in reference-based metagenomics. To improve surveillance, we seek to recover sewage genomes and develop a quantification and correlation workflow for these genomes and AMR over time. We use longitudinal sewage sampling in seven treatment plants from five major European cities to explore the utility of ca... Abstract
Research and practice in thrombosis and haemostasis, Volume 8, Issue 6, 30 5 2024, Pages 102558 Erratum to 'Performance of Risk Scores in Predicting Major Bleeding in Left Ventricular Assist Device (LVAD) Recipients: a Comparative External Validation. '[Res Pract Thromb Haemost. 2024;8:e102437]. van der Horst SFB, de Jong Y, van Rein N, Jukema JW, Palmen M, Janssen E, Bonneville EF, Klok FA, Huisman MV, Tops LF, den Exter PL
[This corrects the article DOI: 10.1016/j.rpth.2024.102437.]. Abstract
Cited 3 times since 2024 (3.1 per year) source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Volume 104, Issue 4, 29 5 2024, Pages 655-663 Intravascular lithotripsy in heavily calcified chronic total occlusion: procedural and one-year clinical outcomes. Oliveri F, van Oort MJH, Al Amri I, Bingen BO, Claessen BE, Dimitriu-Leen AC, Kefer J, Girgis H, Vossenberg T, van der F, Jukema JW, Montero-Cabezas JM
Background: Calcification within chronic total occlusions (CTO) is strongly associated with worse outcomes. Despite the excellent success and safety of intravascular lithotripsy (IVL) in heavily calcified lesions, evidence in CTO remains scarce. Aim: This study aimed to evaluate the procedural and long-term clinical outcomes of IVL in heavily calcified CTO. Methods: Patients who underwent IVL between 2019 and 2024 from an ongoing prospective multicenter registry were eligible for inclusion. Pati... Abstract
Journal of the American Heart Association, Volume 13, Issue 17, 29 5 2024, Pages e034760 Genome-Wide Interaction Analyses of Serum Calcium on Ventricular Repolarization Time in 125 393 Participants. Young WJ, van der Most PJ, Bartz TM, Bos MM, Biino G, Duong T, Foco L, Lominchar JT, Müller-Nurasyid M, Nardone GG, Pecori A, Ramirez J, Repetto L, Schramm K, Shen X, van Duijvenboden S, van Heemst D, Weiss S, Yao J, Benjamins JW, Alonso A, Spedicati B, Biggs ML, Brody JA, Dörr M, Fuchsberger C, Gögele M, Guo X, Ikram MA, Jukema JW, Kääb S, Kanters JK, Lifelines Cohort Study, Lin HJ, Linneberg A, Nauck M, Nolte IM, Pianigiani G, Santin A, Soliman EZ, Tesolin P, Vaccargiu S, Waldenberger M, van der Harst P, Verweij N, Arking DE, Concas MP, De Grandi A, Girotto G, Grarup N, Kavousi M, Mook-Kanamori DO, Navarro P, Orini M, Padmanabhan S, Pattaro C, Peters A, Pirastu M, Pramstaller PP, Heckbert SR, Sinner M, Snieder H, Völker U, Wilson JF, Gauderman WJ, Lambiase PD, Sotoodehnia N, Tinker A, Warren HR, Noordam R, Munroe PB
Background: Ventricular repolarization time (ECG QT and JT intervals) is associated with malignant arrhythmia. Genome-wide association studies have identified 230 independent loci for QT and JT; however, 50% of their heritability remains unexplained. Previous work supports a causal effect of lower serum calcium concentrations on longer ventricular repolarization time. We hypothesized calcium interactions with QT and JT variant associations could explain a proportion of the missing heritability.... Abstract
Cited 2 times since 2024 (2 per year) source: EuropePMC
European journal of heart failure, Volume 26, Issue 10, 27 4 2024, Pages 2173-2182 Heart failure risk assessment in patients with hypertrophic cardiomyopathy based on the H<sub>2</sub>FPEF score. Laenens D, Zegkos T, Kamperidis V, Wong RCC, Li TY, Sia CH, Kong WKF, Efthimiadis G, Poh KK, Ziakas A, Bax JJ, Ajmone Marsan N
Aims: The aim of this study was to investigate whether the H2FPEF score, which was developed to improve the diagnosis of heart failure (HF) with preserved ejection fraction, is associated with HF outcomes in patients with hypertrophic cardiomyopathy (HCM). Methods and results: Patients with HCM and preserved left ventricular ejection fraction (LVEF ≥50%) were included from a multicentre registry and the H2FPEF score was calculated. Patients were divided into three groups: low (0-1), intermediate... Abstract
Journal of cardiovascular development and disease, Volume 11, Issue 9, 27 4 2024, Pages 264 Exploring Sex Differences in Pain Manifestation of Coronary Artery Disease through Mendelian Randomization. Methorst R, Jongbloed MRM, Noordam R, DeRuiter MC
Pain manifestation following coronary artery disease (CAD) disease differs between men and women. Here, we aimed to provide evidence favoring possible differences in pain manifestation between men and women following CAD using Mendelian randomization (MR). We used summary-level data from sex-stratified genome-wide association studies on CAD and self-reported and clinically diagnosed chest, neck and shoulder, back, and facial pain using data from the UK Biobank cohort (N > 450,000) followed by... Abstract
Cited 8 times since 2024 (8.2 per year) source: EuropePMC
Nature biomedical engineering, Volume 8, Issue 8, 26 4 2024, Pages 941-962 Standardizing designed and emergent quantitative features in microphysiological systems. Nahon DM, Moerkens R, Aydogmus H, Lendemeijer B, Martínez-Silgado A, Stein JM, Dostanić M, Frimat JP, Gontan C, de Graaf MNS, Hu M, Kasi DG, Koch LS, Le KTT, Lim S, Middelkamp HHT, Mooiweer J, Motreuil-Ragot P, Niggl E, Pleguezuelos-Manzano C, Puschhof J, Revyn N, Rivera-Arbelaez JM, Slager J, Windt LM, Zakharova M, van Meer BJ, Orlova VV, de Vrij FMS, Withoff S, Mastrangeli M, van der Meer AD, Mummery CL
Microphysiological systems (MPSs) are cellular models that replicate aspects of organ and tissue functions in vitro. In contrast with conventional cell cultures, MPSs often provide physiological mechanical cues to cells, include fluid flow and can be interlinked (hence, they are often referred to as microfluidic tissue chips or organs-on-chips). Here, by means of examples of MPSs of the vascular system, intestine, brain and heart, we advocate for the development of standards that allow for compa... Abstract
The Science of the total environment, Volume 951, 25 4 2024, Pages 175620 Corrigendum to "Accumulation of airborne microplastics on leaves of different tree species in the urban environment" [Sci. Total Environ. Volume 948, 20 October 2024, page 174907]. Leitão IA, Van Schaik L, Iwasaki S, Ferreira AJD, Geissen V
Cited 2 times since 2024 (2 per year) source: EuropePMC
British journal of cancer, Volume 131, Issue 7, 24 4 2024, Pages 1224-1236 IMPRESS: Improved methylation profiling using restriction enzymes and smMIP sequencing, combined with a new biomarker panel, creating a multi-cancer detection assay. Vandenhoeck J, Neefs I, Vanpoucke T, Ibrahim J, Suls A, Peeters D, Schepers A, Hoischen A, Fransen E, Peeters M, Van Camp G, Op de Beeck K
Background: Despite the worldwide progress in cancer diagnostics, more sensitive diagnostic biomarkers are needed. The methylome has been extensively investigated in the last decades, but a low-cost, bisulfite-free detection method for multiplex analysis is still lacking. Methods: We developed a methylation detection technique called IMPRESS, which combines methylation-sensitive restriction enzymes and single-molecule Molecular Inversion Probes. We used this technique for the development of a mu... Abstract
Cited 1 times since 2024 (1 per year) source: EuropePMC
International journal of cardiology. Heart & vasculature, Volume 54, 22 4 2024, Pages 101494 The use of pledget-reinforced sutures during surgical aortic valve replacement: A systematic review and <i>meta</i>-analysis. Taco Boltje JW, Carvalho Mota MT, Vriesendorp MD, Vonk ABA, Groenwold RHH, Klautz RJM, Velders BJJ
Objective: Literature presents conflicting results on the pros and cons of pledget-reinforced sutures during surgical aortic valve replacement (SAVR). We aimed to investigate the effect of pledget-reinforced sutures versus sutures without pledgets during SAVR on different outcomes in a systematic review and meta-analysis. Methods: A literature search was performed in five different medical literature databases. Studies must include patients undergoing SAVR and must compare any pledget-reinforced... Abstract
Cited 2 times since 2024 (2 per year) source: EuropePMC
JACC. Clinical electrophysiology, Volume 10, Issue 11, 21 3 2024, Pages 2303-2311 Excellent Outcomes After First-Line Ablation in Post-MI Patients With Tolerated VT and LVEF >35. Rademaker R, de Riva M, Piers SRD, Wijnmaalen AP, Zeppenfeld K
Background: Post-myocardial infarction (MI) patients with ventricular tachycardia (VT) are considered at risk for VT recurrence and sudden cardiac death (SCD). Recent guidelines indicate that in selected patients catheter ablation should be considered instead of an implantable cardioverter-defibrillator (ICD). Objectives: This study aimed to analyze outcomes of patients referred for VT ablation according to left ventricular ejection fraction (LVEF), tolerance of VT, and acute ablation outcome. M... Abstract
Mikrochimica acta, Volume 191, Issue 9, 20 3 2024, Pages 548 Monitoring lipopolysaccharide-induced macrophage polarization by surface-enhanced Raman scattering. Yılmaz D, Culha M
Macrophages are among the most important components of the innate immune system where the interaction of pathogens and their phagocytosis occur as the first barrier of immunity. When nanomaterials interact with the human body, they have to face macrophages as well. Thus, understanding of nanomaterials-macrophage interactions and underlying mechanisms is crucial. For this purpose, various methods are used. In this study, surface-enhanced Raman scattering (SERS) is proposed by studying lipopolysac... Abstract
Microbiology spectrum, Volume 12, Issue 10, 20 3 2024, Pages e0094624 Impact of carbon dioxide concentrations on laboratory sensitivity of <i>Mycoplasma</i> species isolated from dairy cows. Biesheuvel MM, Kalbfleisch K, De Buck J, van Engelen E, van Schaik G, Moroni P, Gioia G, Nobrega D, Samera GJ, Adams PJ, Walcott JR, Barkema HW
Conventional Mycoplasma spp. diagnostics involve culture, often considered the gold standard in diagnostic test evaluation. However, culture protocols lack empirical derivation and primarily adhere to National Mastitis Council recommendations, tracing back to initial cultivation of Mycoplasma bovis. Despite a wide range of carbon dioxide (CO2) supplementation reported in literature, specific impacts of CO2 on Mycoplasma spp. growth remain unexplored. Our objective was to assess the effect of CO2... Abstract