9618 results
Cited 28 times since 2013 (2.3 per year)
source: EuropePMC
The Journal of hand surgery,
Volume 38, Issue 6, 4 1 2013, Pages 1202-1208
How surgeons make decisions when the evidence is inconclusive.
Hageman MG, Guitton TG, Ring D, Science of Variation Group
Purpose: To address the factors that surgeons use to decide between 2 options for treatment when the evidence is inconclusive. Methods: We tested the null hypothesis that the factors surgeons use do not vary by training, demographics, and practice. A total of 337 surgeons rated the importance of 7 factors when deciding between treatment and following the natural history of the disease and 12 factors when deciding between 2 operative treatments using a 5-point Likert scale between "very impo...
Abstract
Cited 24 times since 2013 (2 per year)
source: EuropePMC
BMC genomics,
Volume 14, 3 1 2013, Pages 299
Functional genomic analysis of bile salt resistance in Enterococcus faecium.
Zhang X, Bierschenk D, Top J, Anastasiou I, Bonten MJ, Willems RJ, van Schaik W
Background: Enterococcus faecium is a Gram-positive commensal bacterium of the mammalian intestinal tract. In the last two decades it has also emerged as a multi-resistant nosocomial pathogen. In order to survive in and colonize the human intestinal tract E. faecium must resist the deleterious actions of bile. The molecular mechanisms exploited by this bacterium to tolerate bile are as yet unexplored. Results: In this study we used a high-throughput quantitative screening approach of transposon...
Abstract
Cited 4 times since 2013 (0.3 per year)
source: EuropePMC
International journal of cardiology,
Volume 168, Issue 4, 3 1 2013, Pages 3327-3333
Exercise-resembling effects of periodic somatosensory stimulation in heart failure.
Gademan MG, van Exel HJ, van de Vooren H, Haest JC, van Pelt J, van der Laarse A, Cannegieter SC, Lucas CM, Somer S, Verwey HF, Schalij MJ, van der Wall EE, Swenne CA
Background: The mechanism of the beneficial effects of exercise training on autonomic derangement and neurohumoral activation in chronic heart failure (CHF) is largely unexplained. In our here-presented hypothesis-generating study we propose that part of these effects is mediated by the exercise-accompanying somatosensory nerve traffic. To demonstrate this, we compared the effects of periodic electrical somatosensory stimulation in patients with CHF with the effects of exercise training and with...
Abstract
Cited 17 times since 2013 (1.4 per year)
source: EuropePMC
International journal of cardiology,
Volume 168, Issue 4, 3 1 2013, Pages 3212-3216
Complications of pacemaker therapy in adults with congenital heart disease: a multicenter study.
Opić P, van Kranenburg M, Yap SC, van Dijk AP, Budts W, Vliegen HW, van Erven L, Can A, Sahin G, Theuns DA, Witsenburg M, Roos-Hesselink JW
Background: This study aims to investigate indications and complications of permanent cardiac pacing in adults with congenital heart disease (CHD). Methods and results: Two-hundred and seventy-four CHD patients were identified who underwent permanent pacemaker implantation between 1972 and 2009. The indication for pacing was acquired sinus node or AV node conduction disease (63%), sinus node or AV node conduction disease after cardiac surgery (28%), and drug/arrhythmia-related indications (9%)....
Abstract
Cited 76 times since 2013 (6.2 per year)
source: EuropePMC
Clinical cancer research : an official journal of the American Association for Cancer Research,
Volume 19, Issue 12, 2 1 2013, Pages 3316-3324
CYP3A4*22 genotype and systemic exposure affect paclitaxel-induced neurotoxicity.
de Graan AJ, Elens L, Sprowl JA, Sparreboom A, Friberg LE, van der Holt B, de Raaf PJ, de Bruijn P, Engels FK, Eskens FA, Wiemer EA, Verweij J, Mathijssen RH, van Schaik RH
Purpose: Paclitaxel is used for the treatment of several solid tumors and displays a high interindividual variation in exposure and toxicity. Neurotoxicity is one of the most prominent side effects of paclitaxel. This study explores potential predictive pharmacokinetic and pharmacogenetic determinants for the onset and severity of neurotoxicity. Experimental design: In an exploratory cohort of patients (n = 261) treated with paclitaxel, neurotoxicity incidence, and severity, pharmacokinetic para...
Abstract
Cited 67 times since 2013 (5.4 per year)
source: EuropePMC
Journal of pain research,
Volume 6, 1 1 2013, Pages 331-353
Consequences of the 118A>G polymorphism in the OPRM1 gene: translation from bench to bedside?
Mura E, Govoni S, Racchi M, Carossa V, Ranzani GN, Allegri M, van Schaik RH
The 118A>G single nucleotide polymorphism (SNP) in the μ-opioid receptor (OPRM1) gene has been the most described variant in pharmacogenetic studies regarding opioid drugs. Despite evidence for an altered biological function encoded by this variant, this knowledge is not yet utilized clinically. The aim of the present review was to collect and discuss the available information on the 118A>G SNP in the OPRM1 gene, at the molecular level and in its clinical manifestations. In vitro biochemic...
Abstract
Cited 1 times since 2013 (0.1 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 21, Issue 5, 1 1 2013, Pages 256-261
Einthoven dissertation prizes 2012.
van der Wall EE, van Gilst WH, Schalij MJ, Umans V
Abstract
Cited 14 times since 2013 (1.1 per year)
source: EuropePMC
The bone & joint journal,
Volume 95-B, Issue 5, 1 1 2013, Pages 689-693
Risk factors for the displacement of fractures of both bones of the forearm in children.
Colaris JW, Allema JH, Reijman M, Biter LU, de Vries MR, van de Ven CP, Bloem RM, Verhaar JA
Forearm fractures in children have a tendency to displace in a cast leading to malunion with reduced functional and cosmetic results. In order to identify risk factors for displacement, a total of 247 conservatively treated fractures of the forearm in 246 children with a mean age of 7.3 years (sd 3.2; 0.9 to 14.9) were included in a prospective multicentre study. Multivariate logistic regression analyses were performed to assess risk factors for displacement of reduced or non-reduced fractures i...
Abstract
Cited 35 times since 2013 (2.8 per year)
source: EuropePMC
Giornale italiano di cardiologia (2006),
Volume 14, Issue 5, 1 1 2013, Pages 328-392
[European Guidelines on Cardiovascular Disease Prevention in Clinical Practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of nine societies and by invited experts)].
Perk J, De Backer G, Gohlke H, Graham I, Reiner Z, Verschuren WM, Albus C, Benlian P, Boysen G, Cifkova R, Deaton C, Ebrahim S, Fisher M, Germanò G, Hobbs R, Hoes A, Karadeniz S, Mezzani A, Prescott E, Ryden L, Scherer M, Syvanne M, Scholte Op Reimer WJ, Vrints C, Wood D, Zamorano JL, Zannad F, Comitato per Linee Guida Pratiche (CPG) dell'ESC
Abstract
Cited 18 times since 2013 (1.5 per year)
source: EuropePMC
Respiratory medicine,
Volume 107, Issue 7, 30 5 2013, Pages 959-966
CD8(+) T cells characterize early smoking-related airway pathology in patients with asthma.
Ravensberg AJ, Slats AM, van Wetering S, Janssen K, van Wijngaarden S, de Jeu R, Rabe KF, Sterk PJ, Hiemstra PS
Background: Smoking in asthma occurs frequently and is associated with increased symptom severity, an impaired response to corticosteroids, and accelerated lung function decline. Airway pathology in smoking asthmatics is characterized by neutrophilia and epithelial changes such as goblet cell hyperplasia and increased proliferation. Bronchial CD8(+) T cells are implicated in lung function decline in asthma and COPD. We hypothesized that smoking modifies airway inflammation in asthma by increasin...
Abstract
Cited 40 times since 2013 (3.2 per year)
source: EuropePMC
American heart journal,
Volume 166, Issue 1, 30 5 2013, Pages 20-29
Effect of atrioventricular and ventriculoventricular delay optimization on clinical and echocardiographic outcomes of patients treated with cardiac resynchronization therapy: a meta-analysis.
Auger D, Hoke U, Bax JJ, Boersma E, Delgado V
Background: Optimization of atrioventricular (AV) and ventriculoventricular (VV) delays of cardiac resynchronization therapy (CRT) devices maximizes left ventricular filling and stroke volume. However, the incremental value of these optimizations over empiric device programming remains unclear. The objective of this analysis was to perform a systematic review and meta-analysis of the effects of AV and VV delay optimization on clinical and echocardiographic end points of patients with heart failu...
Abstract
Cited 23 times since 2013 (1.9 per year)
source: EuropePMC
Journal of cardiothoracic and vascular anesthesia,
Volume 27, Issue 4, 28 4 2013, Pages 723-727
Determinants of clinical right ventricular failure after congenital heart surgery in adults.
Schuuring MJ, van Gulik EC, Koolbergen DR, Hazekamp MG, Lagrand WK, Backx AP, Mulder BJ, Bouma BJ
Objectives: Right ventricular (RV) failure after cardiac surgery is a clinical entity with high morbidity and mortality. Patients with congenital heart disease (CHD) often undergo right-sided cardiac surgery. The authors aimed to identify determinants of RV failure after cardiac surgery to differentiate patients with increased risk. Design: A retrospective chart review. Setting: University hospital. Participants: Adults with CHD operated on between January 2001 and January 2011. Interventions: C...
Abstract
Cited 7 times since 2013 (0.6 per year)
source: EuropePMC
International journal of cardiology,
Volume 168, Issue 3, 26 4 2013, Pages 3031-3032
Long term effects of intramyocardial bone marrow cell injection on anginal symptoms and quality of life in patients with chronic myocardial ischemia.
van Ramshorst J, Rodrigo SF, Beeres SL, Fibbe WE, Zwaginga JJ, Bax JJ, Schalij MJ, Atsma DE
Abstract
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 44, Issue 4, 26 4 2013, Pages 654-655
Very early repair of tetralogy of Fallot: we can, but should we?
Hazekamp MG
Abstract
Cited 45 times since 2013 (3.7 per year)
source: EuropePMC
Cyberpsychology, behavior and social networking,
Volume 16, Issue 7, 25 4 2013, Pages 497-503
Display of alcohol use on Facebook: a content analysis.
Beullens K, Schepers A
The present study has two main objectives. First, to examine how alcohol use is portrayed in the visual and textual references on Facebook, and second, to determine how friends react to these alcohol-related postings. A theoretically based content analysis of 160 Facebook profiles generated 2,575 pictures and 92 status updates referring to alcohol use, which represented about 6.50% of the pictures in the total sample and 2.90% of the status updates. These visual and textual references, as well a...
Abstract
Cited 63 times since 2013 (5.1 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 6, Issue 3, 25 4 2013, Pages 513-521
Outcome of ventricular tachycardia ablation in patients with nonischemic cardiomyopathy: the impact of noninducibility.
Piers SR, Leong DP, van Huls van Taxis CF, Tayyebi M, Trines SA, Pijnappels DA, Delgado V, Schalij MJ, Zeppenfeld K
Background: Ablation failure and recurrence rates after ventricular tachycardia (VT) ablation in nonischemic cardiomyopathy are high and the optimal procedural end point is not well defined. This study assessed the outcome after ablation, the impact of noninducibility, and other potential predictors of VT recurrence. Methods and results: Forty-five patients with nonischemic cardiomyopathy (60±16 years; left ventricular ejection fraction, 44±14%) accepted for VT ablation were included. Epicardial...
Abstract
Cited 29 times since 2013 (2.4 per year)
source: EuropePMC
The American journal of cardiology,
Volume 111, Issue 10, 24 4 2013, Pages 1387-1393
Peak and fixed-time high-sensitive troponin for prediction of infarct size, impaired left ventricular function, and adverse outcomes in patients with first ST-segment elevation myocardial infarction receiving percutaneous coronary intervention.
Boden H, Ahmed TA, Velders MA, van der Hoeven BL, Hoogslag GE, Bootsma M, le Cessie S, Cobbaert CM, Delgado V, van der Laarse A, Schalij MJ
The clinical use of advanced imaging modalities for early determination of infarct size and prognosis is limited. As a specific indicator of myocardial necrosis, cardiac troponin T (cTnT) can be used as a surrogate measure for this purpose. The present study sought to investigate the use of peak and serial 6-hour fixed-time high-sensitive (hs) cTnT for estimation of infarct size, left ventricular (LV) function, and prognosis in consecutive patients with ST-segment elevation myocardial infarction...
Abstract
Cited 69 times since 2013 (5.6 per year)
source: EuropePMC
PloS one,
Volume 8, Issue 4, 24 4 2013, Pages e62395
Citation analysis may severely underestimate the impact of clinical research as compared to basic research.
van Eck NJ, Waltman L, van Raan AF, Klautz RJ, Peul WC
Background: Citation analysis has become an important tool for research performance assessment in the medical sciences. However, different areas of medical research may have considerably different citation practices, even within the same medical field. Because of this, it is unclear to what extent citation-based bibliometric indicators allow for valid comparisons between research units active in different areas of medical research. Methodology: A visualization methodology is introduced that reve...
Abstract
Cited 8 times since 2013 (0.6 per year)
source: EuropePMC
Forensic science international,
Volume 230, Issue 1-3, 23 4 2013, Pages 37-45
Pentaerythritol tetranitrate (PETN) profiling in post-explosion residues to constitute evidence of crime-scene presence.
Brust H, van Asten A, Koeberg M, van der Heijden A, Kuijpers CJ, Schoenmakers P
Pentaerythritol tetranitrate (PETN) and its degradation products are analyzed to discriminate between residues originating from PETN explosions and residues obtained under other circumstances, such as natural degradation on textile, or after handling intact PETN. The degradation products observed in post-explosion samples were identified using liquid chromatography-mass spectrometry as the less-nitrated analogues of PETN: pentaerythritol trinitrate (PETriN), pentaerythritol dinitrate (PEDiN) and...
Abstract
Cited 81 times since 2013 (6.6 per year)
source: EuropePMC
Annals of the rheumatic diseases,
Volume 73, Issue 4, 20 3 2013, Pages 756-762
Rheumatoid arthritis synovial tissue harbours dominant B-cell and plasma-cell clones associated with autoreactivity.
Doorenspleet ME, Klarenbeek PL, de Hair MJ, van Schaik BD, Esveldt RE, van Kampen AH, Gerlag DM, Musters A, Baas F, Tak PP, de Vries N
Objective: To identify potential autoreactive B-cell and plasma-cell clones by quantitatively analysing the complete human B-cell receptor (BCR) repertoire in synovium and peripheral blood in early and established rheumatoid arthritis (RA). Methods: The BCR repertoire was screened in synovium and blood of six patients with early RA (ERA) (20 months). In two patients, the repertoires in different joints were compared. Repertoires were analysed by next-generation sequencing from mRNA, generating &...
Abstract
