Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
9618 results
Cited 12 times since 2012 (0.9 per year) source: EuropePMC
Experimental physiology, Volume 98, Issue 3, 12 2 2012, Pages 710-721 The identification of genetic pathways involved in vascular adaptations after physical deconditioning versus exercise training in humans. Lammers G, van Duijnhoven NT, Hoenderop JG, Horstman AM, de Haan A, Janssen TW, de Graaf MJ, Pardoel EM, Verwiel ET, Thijssen DH, Hopman MT
Physical inactivity and exercise training result in opposite adaptations of vascular structure. However, the molecular mechanisms behind these adaptations are not completely understood. We used a unique study design to examine both vascular characteristics of the superficial femoral artery (using ultrasound) and gene expression levels (from a muscle biopsy) in human models for physical deconditioning and exercise training. Initially, we compared able-bodied control subjects (n = 6) with spinal c... Abstract
Cited 4 times since 2012 (0.3 per year) source: EuropePMC
BMC veterinary research, Volume 8, 11 2 2012, Pages 188 No long-term influence of movement restriction regulations on the contact-structure between and within cattle holding types in the Netherlands. Brouwer H, Bartels CJ, Stegeman A, van Schaik G
Background: More and more countries hold databases on cattle movements. The primary purpose of the registration of cattle movements is to provide data for quick tracing of contagious animals in case of disease outbreaks and food safety scares. Nevertheless, these data can also be used for analytical studies to get insight into the nature of the contact structure between and within cattle holding types. This paper focuses on the effect post-2001 FMD movement regulations have had on the number of... Abstract
Cited 38 times since 2012 (3 per year) source: EuropePMC
PloS one, Volume 7, Issue 10, 11 2 2012, Pages e46855 Risk of cardiovascular disease in a traditional African population with a high infectious load: a population-based study. Koopman JJ, van Bodegom D, Jukema JW, Westendorp RG
Background: To test the inflammatory origin of cardiovascular disease, as opposed to its origin in western lifestyle. Population-based assessment of the prevalences of cardiovascular risk factors and cardiovascular disease in an inflammation-prone African population, including electrocardiography and ankle-arm index measurement. Comparison with known prevalences in American and European societies. Methodology/principal findings: Traditional population in rural Ghana, characterised by adverse env... Abstract
Cited 36 times since 2012 (2.8 per year) source: EuropePMC
PloS one, Volume 7, Issue 10, 11 2 2012, Pages e47134 Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression. de Vries MR, Niessen HW, Löwik CW, Hamming JF, Jukema JW, Quax PH
The current study describes the incidence and phenotype of plaque rupture complications in murine vein grafts. Since matrix metalloproteinases (MMPs) are highly involved in atherosclerotic plaque vulnerability and plaque rupture, we hypothesized that this model can be validated by overexpression of the MMP inhibitor TIMP-1. First we studied 47 vein grafts in hypercholesterolemic ApoE3*Leiden mice for the incidence of plaque complications. In 79% of these grafts, extensive lesions with plaque rup... Abstract
Cited 12 times since 2012 (0.9 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 60, Issue 19, 10 2 2012, Pages 1991-1992 Does pregnancy influence the durability of human aortic valve substitutes? Arabkhani B, Heuvelman HJ, Bogers AJ, Mokhles MM, Roos-Hesselink JW, Takkenberg JJ
Cited 1 times since 2012 (0.1 per year) source: EuropePMC
Cardiology in the young, Volume 23, Issue 4, 2 1 2012, Pages 540-545 Peri-operative care in adults with congenital heart disease: room for improvement in after care. Schoormans D, Smets EM, Zwart R, Sprangers MA, Veelenturg TH, de Mol BA, Hazekamp MG, Koolbergen DR, Sojak V, Bouma BJ, Groenink M, Boekholdt MS, Backx AP, Mulder BJ
Background: Patient satisfaction with care has received little attention within the field of congenital heart disease. Our objective was to examine patient satisfaction with the care received when undergoing open-heart surgery in order to identify the best and worst aspects of peri-operative care. Moreover, we examined whether having contact with a specialised nurse in addition to usual care is associated with higher patient satisfaction levels. Methods: Patient satisfaction was measured by the... Abstract
Expert review of cardiovascular therapy, Volume 10, Issue 10, 1 1 2012, Pages 1197-1199 Primary prevention implantable cardioverter-defibrillator treatment: how to identify patients most likely to benefit? Thijssen J, van Rees JB, Schalij MJ, Borleffs CJ
European heart journal, Volume 34, Issue 12, 1 1 2012, Pages 941 Dissection and ruptured pseudoaneurysm of a renal artery: a non-described complication during transcatheter aortic-valve implantation. Roman AJ, Montero Cabezas JM, Alonso AR, Gonzalez-Trevilla AA
Cited 80 times since 2012 (6.2 per year) source: EuropePMC
Rapid communications in mass spectrometry : RCM, Volume 26, Issue 20, 1 1 2012, Pages 2461-2471 Substructure-based annotation of high-resolution multistage MS(n) spectral trees. Ridder L, van der Hooft JJ, Verhoeven S, de Vos RC, van Schaik R, Vervoort J
Rationale: High-resolution multistage MS(n) data contains detailed information that can be used for structural elucidation of compounds observed in metabolomics studies. However, full exploitation of this complex data requires significant analysis efforts by human experts. In silico methods currently used to support data annotation by assigning substructures of candidate molecules are limited to a single level of MS fragmentation. Methods: We present an extended substructure-based approach which... Abstract
Cited 9 times since 2012 (0.7 per year) source: EuropePMC
Transplantation, Volume 94, Issue 7, 1 1 2012, Pages 721-728 Late calcineurin inhibitor withdrawal prevents progressive left ventricular diastolic dysfunction in renal transplant recipients. Mourer JS, Ewe SH, Mallat MJ, Ng AC, Rabelink TJ, Bax JJ, Delgado V, de Fijter JW
Background: Calcineurin inhibitor (CNI)-based therapy is associated with adverse cardiovascular effects. We examined the effects of late CNI or mycophenolate mofetil (MMF) withdrawal on echocardiographic parameters. Methods: This study was conducted as a substudy of a randomized trial in stable renal transplant recipients who were on a triple CNI-based regimen with prednisone and MMF that evaluated late concentration-controlled withdrawal of CNI or MMF on renal function. A total of 108 patients... Abstract
Cited 7 times since 2012 (0.5 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 20, Issue 10, 1 1 2012, Pages 419-424 Prosthetic valves in adult patients with congenital heart disease: Rationale and design of the Dutch PROSTAVA study. Freling HG, van Slooten YJ, van Melle JP, Mulder BJ, van Dijk AP, Hillege HL, Post MC, Sieswerda GT, Jongbloed MR, Willems TP, Pieper PG, PROSTAVA investigators
Background: Data on long-term complications in adult patients with congenital heart disease (ACHD) and a prosthetic valve are scarce. Moreover, the influence of prosthetic valves on quality of life (QoL) and functional outcome in ACHD patients with prosthetic valves has not been studied. Objectives: The primary objective of the PROSTAVA study is to investigate the relation between prosthetic valve characteristics (type, size and location) and functional outcome as well as QoL in ACHD patients. T... Abstract
Cited 5 times since 2012 (0.4 per year) source: EuropePMC
Journal of medical physics, Volume 37, Issue 4, 1 1 2012, Pages 235-239 Radiotherapy pre-treatment dose validation: A second verification of monitor units (MU) with a commercial software. Al Amri I, Ravichandran R, Sivakumar SS, Binukumar JP, Davis CA, Al Rahbi Z, Al Shukeili K, Al Kindi F
Inversely planned intensity-modulated radiotherapy (IMRT) and stereotactic small field radiotherapy should be verified before treatment execution. A second verification is carried out for planned treatments in IMRT and 3D conformal radiotherapy (3D-CRT) using a monitor verification commercial dose calculation management software (DCMS). For the same reference point the ion-chamber measured doses are compared for IMRT plans. DCMS (Diamond) computes dose based on modified Clarkson integration, acc... Abstract
Cited 32 times since 2012 (2.5 per year) source: EuropePMC
Journal of cellular and molecular medicine, Volume 16, Issue 10, 1 1 2012, Pages 2440-2450 Shear induced collateral artery growth modulated by endoglin but not by ALK1. Seghers L, de Vries MR, Pardali E, Hoefer IE, Hierck BP, ten Dijke P, Goumans MJ, Quax PH
Transforming growth factor-beta (TGF-β) stimulates both ischaemia induced angiogenesis and shear stress induced arteriogenesis by signalling through different receptors. How these receptors are involved in both these processes of blood flow recovery is not entirely clear. In this study the role of TGF-β receptors 1 and endoglin is assessed in neovascularization in mice. Unilateral femoral artery ligation was performed in mice heterozygous for either endoglin or ALK1 and in littermate controls. C... Abstract
Cited 5 times since 2012 (0.4 per year) source: EuropePMC
Lancet (London, England), Volume 380, Issue 9852, 1 1 2012, Pages 1471-1472 Hypertension in developing countries. Koopman JJ, van Bodegom D, Beenakker KG, Jukema JW, Westendorp RG
Cited 16 times since 2012 (1.2 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 98, Issue 20, 1 1 2012, Pages 1529-1536 Late acquired stent malapposition: why, when and how to handle? Karalis I, Ahmed TA, Jukema JW
Cited 16 times since 2012 (1.2 per year) source: EuropePMC
Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, Volume 40 Suppl 3, 1 1 2012, Pages 77-137 [ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012]. McMurray JJ, Adamopoulos S, Anker SD, Auricchio A, Böhm M, Dickstein K, Falk V, Filippatos G, Fonseca C, Gomez-Sanchez MA, Jaarsma T, Kober L, Lip GY, Maggioni AP, Parkhomenko A, Pieske BM, Popescu BA, Ronnevik K, Rutten FH, Schwitter J, Seferovic P, Stepinska J, Trindade PT, Voors AA, Zannad Falez, Zeiher A, Avrupa Kardiyoloji Derneği (ESC) Akut ve Kronik Kalp Yetersizliği Tani ve Tedavisi 2012 Görev Grubu, ESC Kalp Yetersizliği Birliğinin Işbirliğiyle hazirlanmiştir, Heart Failure Association
Cited 28 times since 2012 (2.2 per year) source: EuropePMC
Preventive veterinary medicine, Volume 109, Issue 1-2, 29 5 2012, Pages 76-82 Demography of Q fever seroprevalence in sheep and goats in The Netherlands in 2008. Van den Brom R, Moll L, van Schaik G, Vellema P
At the end of 2007, the first year of what later turned out to be one of the largest Q fever outbreaks in the world with ultimately almost 3500 human patients notified in three years time, dairy goats were suspected to be the possible cause. However, current information on the Q fever prevalence in small ruminants in The Netherlands was lacking. A serological survey, using an indirect ELISA, was carried out in 15,186 sheep and goats in The Netherlands in 2008. In total, 2.4% (95% CI: 2.2-2.7) of... Abstract
Cited 17 times since 2012 (1.3 per year) source: EuropePMC
The international journal of cardiovascular imaging, Volume 29, Issue 3, 28 4 2012, Pages 609-616 Relationship between left ventricular diastolic function and arterial stiffness in asymptomatic patients with diabetes mellitus. Roos CJ, Auger D, Djaberi R, de Koning EJ, Rabelink TJ, Pereira AM, Bax JJ, Delgado V, Jukema JW, Scholte AJ
Left ventricular (LV) diastolic dysfunction and increased arterial stiffness are common in patients with diabetes mellitus (DM). However, the relation between these two pathophysiological factors remains unclear. The aim of this study was to investigate the relationship between LV diastolic function and arterial stiffness as assessed with applanation tonometry. In 142 asymptomatic patients with DM (mean age 48 years, 75 (53 %) men, 72 (51 %) patients with type 2 DM) LV diastolic function was ass... Abstract
Cited 148 times since 2012 (11.5 per year) source: Scopus
European journal of preventive cardiology, Volume 20, Issue 4, 28 4 2012, Pages 620-640 Lifestyle modification programmes for patients with coronary heart disease: a systematic review and meta-analysis of randomized controlled trials. Janssen V, De Gucht V, Dusseldorp E, Maes S
Background: Lifestyle modification programmes for coronary heart disease patients have been shown to effectively improve risk factors and related health behaviours, quality of life, reincidence, and mortality. However, improvements in routine cardiac care over the recent years may offset the incremental benefit associated with older programmes. Purpose: To determine the efficacy of lifestyle modification programmes for coronary heart disease patients developed over the last decade (1999-2009) by... Abstract
Cited 33 times since 2012 (2.6 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 15, Issue 2, 28 4 2012, Pages 290-296 Incremental prognostic value of an abnormal baseline spatial QRS-T angle in chronic dialysis patients. de Bie MK, Koopman MG, Gaasbeek A, Dekker FW, Maan AC, Swenne CA, Scherptong RW, van Dessel PF, Wilde AA, Schalij MJ, Rabelink TJ, Jukema JW
Aims: In order to improve the abysmal outcome of dialysis patients, it is critical to identify patients with a high mortality risk. The spatial QRS-T angle, which can be easily calculated from the 12 lead electrocardiogram (ECG), might be useful in the prognostication in dialysis patients. The objective of this study was to establish the prognostic value of the spatial QRS-T angle. Methods and results: All patients who initiated dialysis therapy between 2002 and 2009 in the hospitals of Leiden (... Abstract