9618 results
Cited 8 times since 2022 (2.6 per year)
source: EuropePMC
Microbiology spectrum,
Volume 10, Issue 4, 1 1 2022, Pages e0248421
Primary Murine Macrophages as a Tool for Virulence Factor Discovery in Coxiella burnetii.
Case EDR, Mahapatra S, Hoffpauir CT, Konganti K, Hillhouse AE, Samuel JE, Van Schaik EJ
Coxiella burnetii requires a type IVB secretion system (T4SS) to promote intracellular replication and virulence. We hypothesized that Coxiella employs its T4SS to secrete effectors that enable stealthy colonization of immune cells. To address this, we used RNA sequencing to compare the transcriptional response of murine bone marrow-derived macrophages (BMDM) infected with those of wild-type Coxiella and a T4SS-null mutant at 8 and 24 h postinfection. We found a T4SS-independent upregulation of...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
Rheumatology (Oxford, England),
Volume 61, Issue 8, 1 1 2022, Pages 3420-3426
Assessment of disability in idiopathic inflammatory myopathy: a call for linearity.
Min M, Walter AW, Lim J, Eftimov F, Verhamme C, de Visser M, van Schaik IN, Aggarwal R, de Haan RJ, van der Kooi AJ, Raaphorst J, Dutch Myositis Network
Objectives: To evaluate the clinimetric properties of the Academic Medical Centre Disability Score (ALDS) in patients with idiopathic inflammatory myopathy (IIM). Methods: We used prospectively collected data of IIM patients who completed a phase-2 study with first-line IVIG monotherapy. The ALDS is a patient-reported questionnaire which contains 25 items relevant for disability in myositis. ALDS and all core set measures (CSMs) for myositis [including HAQ-Disability Index (HAQ-DI)] were evaluat...
Abstract
Cited 14 times since 2022 (4.6 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 62, Issue 3, 1 1 2022, Pages ezac374
Surgical aortic valve replacement with a stented pericardial bioprosthesis: 5-year outcomes.
Klautz RJM, Dagenais F, Reardon MJ, Lange R, Moront MG, Labrousse L, Weissman NJ, Rao V, Patel HJ, Liu F, Sabik JF
Objectives: This analysis evaluated the safety, durability and haemodynamic performance of a stented bovine pericardial valve through 5 years of follow-up in patients with an indication for surgical aortic valve replacement. Methods: Kaplan-Meier analysis was used to estimate the incidence of survival and valve-related thromboembolism, major paravalvular leak, endocarditis, structural valve deterioration (SVD) and reintervention. The mean aortic gradient and New York Heart Association (NYHA) fun...
Abstract
Cited 9 times since 2022 (2.9 per year)
source: EuropePMC
BMJ open,
Volume 12, Issue 8, 1 1 2022, Pages e055324
Effectiveness and implementation of SHared decision-making supported by OUTcome information among patients with breast cancer, stroke and advanced kidney disease: SHOUT study protocol of multiple interrupted time series.
Hackert MQN, Ankersmid JW, Engels N, Prick JCM, Teerenstra S, Siesling S, Drossaert CHC, Strobbe LJA, van Riet YEA, van den Dorpel RMA, Bos WJW, van der Nat PB, van den Berg-Vos RM, van Schaik SM, Garvelink MM, van der Wees PJ, van Uden-Kraan CF, Santeon VBHC breast cancer, stroke and chronic kidney disease group
Introduction: Within the value-based healthcare framework, outcome data can be used to inform patients about (treatment) options, and empower them to make shared decisions with their health care professional. To facilitate shared decision-making (SDM) supported by outcome data, a multicomponent intervention has been designed, including patient decision aids on the organisation of post-treatment surveillance (breast cancer); discharge location (stroke) and treatment modality (advanced kidney dise...
Abstract
Cited 35 times since 2022 (11.5 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 23, Issue 9, 1 1 2022, Pages e308-e322
Cardiovascular magnetic resonance in autoimmune rheumatic diseases: a clinical consensus document by the European Association of Cardiovascular Imaging.
Mavrogeni S, Pepe A, Nijveldt R, Ntusi N, Sierra-Galan LM, Bratis K, Wei J, Mukherjee M, Markousis-Mavrogenis G, Gargani L, Sade LE, Ajmone-Marsan N, Seferovic P, Donal E, Nurmohamed M, Cerinic MM, Sfikakis P, Kitas G, Schwitter J, Lima JAC, Dawson D, Dweck M, Haugaa KH, Keenan N, Moon J, Stankovic I, Donal E, Cosyns B
Autoimmune rheumatic diseases (ARDs) involve multiple organs including the heart and vasculature. Despite novel treatments, patients with ARDs still experience a reduced life expectancy, partly caused by the higher prevalence of cardiovascular disease (CVD). This includes CV inflammation, rhythm disturbances, perfusion abnormalities (ischaemia/infarction), dysregulation of vasoreactivity, myocardial fibrosis, coagulation abnormalities, pulmonary hypertension, valvular disease, and side-effects o...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 62, Issue 3, 1 1 2022, Pages ezac240
Mechanical circulatory support in the failing systemic right ventricle: a step towards better outcome.
Koolbergen DR
Abstract
Cited 43 times since 2022 (14.1 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 80, Issue 5, 1 1 2022, Pages 545-561
Standardized Definitions for Bioprosthetic Valve Dysfunction Following Aortic or Mitral Valve Replacement: JACC State-of-the-Art Review.
Pibarot P, Herrmann HC, Wu C, Hahn RT, Otto CM, Abbas AE, Chambers J, Dweck MR, Leipsic JA, Simonato M, Rogers T, Sathananthan J, Guerrero M, Ternacle J, Wijeysundera HC, Sondergaard L, Barbanti M, Salaun E, Généreux P, Kaneko T, Landes U, Wood DA, Deeb GM, Sellers SL, Lewis J, Madhavan M, Gillam L, Reardon M, Bleiziffer S, O'Gara PT, Rodés-Cabau J, Grayburn PA, Lancellotti P, Thourani VH, Bax JJ, Mack MJ, Leon MB, Heart Valve Collaboratory
Bioprosthetic valve dysfunction (BVD) and bioprosthetic valve failure (BVF) may be caused by structural or nonstructural valve dysfunction. Both surgical and transcatheter bioprosthetic valves have limited durability because of structural valve deterioration. The main objective of this summary of experts participating in a virtual workshop was to propose standardized definitions for nonstructural and structural BVD and BVF following aortic or mitral biological valve replacement with the goal of...
Abstract
Cited 26 times since 2022 (8.5 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 80, Issue 5, 1 1 2022, Pages 527-544
Bioprosthetic Aortic Valve Hemodynamics: Definitions, Outcomes, and Evidence Gaps: JACC State-of-the-Art Review.
Herrmann HC, Pibarot P, Wu C, Hahn RT, Tang GHL, Abbas AE, Playford D, Ruel M, Jilaihawi H, Sathananthan J, Wood DA, De Paulis R, Bax JJ, Rodes-Cabau J, Cameron DE, Chen T, Del Nido PJ, Dweck MR, Kaneko T, Latib A, Moat N, Modine T, Popma JJ, Raben J, Smith RL, Tchetche D, Thomas MR, Vincent F, Yoganathan A, Zuckerman B, Mack MJ, Leon MB, Heart Valve Collaboratory
A virtual workshop was organized by the Heart Valve Collaboratory to identify areas of expert consensus, areas of disagreement, and evidence gaps related to bioprosthetic aortic valve hemodynamics. Impaired functional performance of bioprosthetic aortic valve replacement is associated with adverse patient outcomes; however, this assessment is complicated by the lack of standardization for labelling, definitions, and measurement techniques, both after surgical and transcatheter valve replacement....
Abstract
Cited 17 times since 2022 (5.6 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 80, Issue 7, 1 1 2022, Pages 666-676
Prevalence and Prognostic Implications of Discordant Grading and Flow-Gradient Patterns in Moderate Aortic Stenosis.
Stassen J, Ewe SH, Singh GK, Butcher SC, Hirasawa K, Amanullah MR, Pio SM, Sin KYK, Ding ZP, Sia CH, Chew NWS, Kong WKF, Poh KK, Leon MB, Pibarot P, Delgado V, Marsan NA, Bax JJ
Background: The prognostic implications of discordant grading in severe aortic stenosis (AS) are well known. However, the prevalence of different flow-gradient patterns and their prognostic implications in moderate AS are unknown. Objectives: The purpose of this study was to investigate the occurrence and prognostic implications of different flow-gradient patterns in patients with moderate AS. Methods: Patients with moderate AS (aortic valve area >1.0 and ≤1.5 cm2) were identified and divided...
Abstract
Cited 7 times since 2022 (2.3 per year)
source: EuropePMC
Journal of cardiovascular pharmacology,
Volume 80, Issue 2, 1 1 2022, Pages 276-293
Activation of GPR75 Signaling Pathway Contributes to the Effect of a 20-HETE Mimetic, 5,14-HEDGE, to Prevent Hypotensive and Tachycardic Responses to Lipopolysaccharide in a Rat Model of Septic Shock.
Tunctan B, Senol SP, Temiz-Resitoglu M, Yilmaz DE, Guden DS, Bahceli O, Horat MF, Sahan-Firat S, Sari AN, Falck JR, Anugu RR, Malik KU
Abstract: The orphan receptor, G protein-coupled receptor (GPR) 75, which has been shown to mediate various effects of 20-hydroxyeicosatetraenoic acid (20-HETE), is considered as a therapeutic target in the treatment of cardiovascular diseases in which changes in the production of 20-HETE play a key role in their pathogenesis. Our previous studies showed that 20-HETE mimetic, N -(20-hydroxyeicosa-5[Z],14[Z]-dienoyl)glycine (5,14-HEDGE), protects against vascular hyporeactivity, hypotension, tach...
Abstract
Pediatric nephrology (Berlin, Germany),
Volume 37, Issue 8, 1 1 2022, Pages 1943-1944
Correction to: Impact of coronavirus disease-2019 on pediatric nephrology practice and education: an ESPN survey.
Yazıcıoğlu B, Bakkaloğlu SA, European Society for Pediatric Nephrology
Abstract
Cited 15 times since 2022 (4.9 per year)
source: EuropePMC
International journal of molecular sciences,
Volume 23, Issue 15, 29 5 2022, Pages 8418
Targeting Fibronectin to Overcome Remyelination Failure in Multiple Sclerosis: The Need for Brain- and Lesion-Targeted Drug Delivery.
van Schaik PEM, Zuhorn IS, Baron W
Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disease with unknown etiology that can be characterized by the presence of demyelinated lesions. Prevailing treatment protocols in MS rely on the modulation of the inflammatory process but do not impact disease progression. Remyelination is an essential factor for both axonal survival and functional neurological recovery but is often insufficient. The extracellular matrix protein fibronectin contributes to the inhibitory enviro...
Abstract
Cited 4 times since 2022 (1.3 per year)
source: EuropePMC
Infant behavior & development,
Volume 68, 29 5 2022, Pages 101751
Infants' sensitivity to emotional expressions in actions: The contributions of parental expressivity and motor experience.
Schröer L, Çetin D, Vacaru SV, Addabbo M, van Schaik JE, Hunnius S
Actions can convey information about the affective state of an actor. By the end of the first year, infants show sensitivity to such emotional information in actions. Here, we examined the mechanisms contributing to infants' developing sensitivity to emotional action kinematics. We hypothesized that this sensitivity might rely on two factors: a stable motor representation of the observed action to be able to detect deviations from how it would typically be performed and experience with emot...
Abstract
Cited 34 times since 2022 (11.1 per year)
source: EuropePMC
Allergy,
Volume 77, Issue 11, 29 5 2022, Pages 3398-3407
Patient-centered dupilumab dosing regimen leads to successful dose reduction in persistently controlled atopic dermatitis.
Spekhorst LS, Bakker D, Drylewicz J, Rispens T, Loeff F, Boesjes CM, Thijs J, Romeijn GLE, Loman L, Schuttelaar ML, van Wijk F, de Graaf M, de Bruin-Weller MS
Background: At present, no real-world studies are available on different dupilumab dosing regimens in controlled atopic dermatitis (AD). The aim of this study was to clinically evaluate a patient-centered dupilumab dosing regimen in patients with controlled AD and to relate this to serum drug levels and serum biomarkers. Methods: Ninety adult AD patients from the prospective BioDay registry were included based on their dupilumab administration interval according to a predefined patient-centered...
Abstract
Cited 3 times since 2022 (1 per year)
source: EuropePMC
JMIR formative research,
Volume 6, Issue 7, 28 4 2022, Pages e38263
COVID-box Experiences of Patients and Health Care Professionals (COVID-box Project): Single-Center, Retrospective, Observational Study.
Dirikgil E, Brons K, Duindam M, Groeneveld GH, Geelhoed JJM, Heringhaus C, van der Boog PJM, Rabelink TJ, Bos WJW, Chavannes NH, Atsma DE, Teng YKO
Background: During the COVID-19 pandemic, several home monitoring programs have described the success of reducing hospital admissions, but only a few studies have investigated the experiences of patients and health care professionals. Objective: The objective of our study was to determine patients' and health care professionals' experiences and satisfaction with employing the COVID-box. Methods: In this single-center, retrospective, observational study, patients and health care profess...
Abstract
Cited 3 times since 2022 (1 per year)
source: EuropePMC
Journal of internal medicine,
Volume 292, Issue 6, 27 4 2022, Pages 892-903
Thyroid antibodies and levothyroxine effects in subclinical hypothyroidism: A pooled analysis of two randomized controlled trials.
Lyko C, Blum MR, Abolhassani N, Stuber MJ, Del Giovane C, Feller M, Moutzouri E, Oberle J, Jungo KT, Collet TH, den Elzen WPJ, Poortvliet RKE, Du Puy RS, Dekkers OM, Trompet S, Jukema JW, Aujesky D, Quinn T, Westendorp R, Kearney PM, Gussekloo J, Van Heemst D, Mooijaart SP, Bauer DC, Rodondi N
Background: Antithyroid antibodies increase the likelihood of developing overt hypothyroidism, but their clinical utility remains unclear. No large randomized controlled trial (RCT) has assessed whether older adults with subclinical hypothyroidism (SHypo) caused by autoimmune thyroid disease derive more benefits from levothyroxine treatment (LT4). Objective: To determine whether older adults with SHypo and positive antibodies derive more clinical benefits from LT4 than those with negative antibo...
Abstract
Cited 6 times since 2022 (2 per year)
source: EuropePMC
Frontiers in immunology,
Volume 13, 27 4 2022, Pages 915687
In rheumatoid arthritis inflamed joints share dominant patient-specific B-cell clones.
Musters A, Balzaretti G, van Schaik BDC, Jongejan A, van der Weele L, Tas SW, van Kampen AHC, de Vries N
Background: In patients with rheumatoid arthritis (RA) different joints were shown to share the same dominant T-cell clones, suggesting shared characteristics of the inflammatory process and indicating that strategies to selectively target the antigen receptor might be feasible. Since T- and B-lymphocytes closely interact in adaptive responses, we analysed to what extent different joints also share dominant B-cell clones. Methods: In 11 RA patients, quantitative B-cell receptor (BCR) repertoire...
Abstract
Cited 3 times since 2022 (1 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 31, Issue 1, 27 4 2022, Pages 16-20
The Netherlands Heart Tissue Bank : Strengthening the cardiovascular research infrastructure with an open access Cardiac Tissue Repository.
Henkens MTHM, van Ast JF, Te Riele ASJM, Houweling AC, Amin AS, Nijveldt R, Antoni ML, Li X, Wehrens SMT, von der Thüsen JH, Damman K, Ter Horst EN, Manintveld OC, Abma-Schouten RY, Niessen HWM, Silljé HHW, Jukema JW, Doevendans PA
Aim: Cardiac diseases remain a leading cause of cardiovascular disease (CVD) related hospitalisation and mortality. That is why research to improve our understanding of pathophysiological processes underlying cardiac diseases is of great importance. There is a strong need for healthy and diseased human cardiac tissue and related clinical data to accomplish this, since currently used animal and in vitro disease models do not fully grasp the pathophysiological processes observed in humans. This de...
Abstract
Cited 2 times since 2022 (0.7 per year)
source: EuropePMC
International journal of environmental research and public health,
Volume 19, Issue 15, 25 4 2022, Pages 9062
Posterior Tibial Nerve Stimulation in Children with Lower Urinary Tract Dysfunction: A Mixed-Methods Analysis of Experiences, Quality of Life and Treatment Effect.
De Wall LL, Bekker AP, Oomen L, Janssen VACT, Kortmann BBM, Heesakkers JPFA, Oerlemans AJM
Background: Posterior tibial nerve stimulation (PTNS) is one of the treatment modalities for children with therapy-refractory lower urinary tract dysfunction (LUTD). This study used a mixed-methods analysis to gain insight into the experiences of children treated with PTNS and their parents, the effect of treatment on quality of life (QOL) and the effect of PTNS on urinary symptoms. Methods: Quantitative outcomes were assessed through a single-centre retrospective chart analysis of all children...
Abstract
Cited 15 times since 2022 (4.9 per year)
source: EuropePMC
Philosophical transactions of the Royal Society of London. Series B, Biological sciences,
Volume 377, Issue 1859, 25 4 2022, Pages 20210098
A convergent interaction engine: vocal communication among marmoset monkeys.
Burkart JM, Adriaense JEC, Brügger RK, Miss FM, Wierucka K, van Schaik CP
To understand the primate origins of the human interaction engine, it is worthwhile to focus not only on great apes but also on callitrichid monkeys (marmosets and tamarins). Like humans, but unlike great apes, callitrichids are cooperative breeders, and thus habitually engage in coordinated joint actions, for instance when an infant is handed over from one group member to another. We first explore the hypothesis that these habitual cooperative interactions, the marmoset interactional ethology,...
Abstract
