9618 results
Cited 21 times since 2021 (5.6 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 8, 10 2 2021, Pages 750016
Echocardiographic Global Longitudinal Strain Is Associated With Myocardial Fibrosis and Predicts Outcomes in Aortic Stenosis.
Le TT, Huang W, Singh GK, Toh DF, Ewe SH, Tang HC, Loo G, Bryant JA, Ang B, Tay EL, Soo WM, Yip JW, Oon YY, Gong L, Lunaria JB, Yong QW, Lee EM, Yeo PSD, Chai SC, Goh PP, Ling LF, Ong HY, Richards AM, Delgado V, Bax JJ, Ding ZP, Ling LH, Chin CWL
Aims: Left ventricular ejection fraction is the conventional measure used to guide heart failure management, regardless of underlying etiology. Left ventricular global longitudinal strain (LV-GLS) by speckle tracking echocardiography (STE) is a more sensitive measure of intrinsic myocardial function. We aim to establish LV-GLS as a marker of replacement myocardial fibrosis on cardiovascular magnetic resonance (CMR) and validate the prognostic value of LV-GLS thresholds associated with fibrosis....
Abstract
Cited 3 times since 2021 (0.8 per year)
source: EuropePMC
F1000Research,
Volume 10, 10 2 2021, Pages 1138
Evaluation of the effect of soft drinks on the surface roughness of dental enamel in natural human teeth.
Al-Amri I, Albounni R, Binalrimal S
Background: Exposing enamel to soft drinks and beverages causes changes in the microscopical morphology. Changes in the physical characteristics, like hardness and surface roughness, were studied with various parameters. Factors such as pH, exposed duration, and other content of the soft drinks have different effects on the enamel. Methods: Thirty-six human premolar teeth were randomly divided into three groups (n=12). Group 1 consisted of teeth which were immersed in artificial saliva (control)...
Abstract
Cited 13 times since 2021 (3.4 per year)
source: EuropePMC
Brain, behavior and evolution,
Volume 96, Issue 3, 9 2 2021, Pages 124-136
Relative Brain Size and Cognitive Equivalence in Fishes.
Triki Z, Aellen M, van Schaik CP, Bshary R
Scientists have long struggled to establish how larger brains translate into higher cognitive performance across species. While absolute brain size often yields high predictive power of performance, its positive correlation with body size warrants some level of correction. It is expected that larger brains are needed to control larger bodies without any changes in cognitive performance. Potentially, the mean value of intraspecific brain-body slopes provides the best available estimate for an int...
Abstract
Cited 7 times since 2021 (1.8 per year)
source: EuropePMC
Circulation. Genomic and precision medicine,
Volume 14, Issue 6, 4 1 2021, Pages e003460
Identification of Functional Genetic Determinants of Cardiac Troponin T and I in a Multiethnic Population and Causal Associations With Atrial Fibrillation.
Yang Y, Bartz TM, Brown MR, Guo X, Zilhão NR, Trompet S, Weiss S, Yao J, Brody JA, Defilippi CR, Hoogeveen RC, Lin HJ, Gudnason V, Ballantyne CM, Dörr M, Jukema JW, Petersmann A, Psaty BM, Rotter JI, Boerwinkle E, Fornage M, Jun G, Yu B
Background: Elevated cardiac troponin levels in blood are associated with increased risk of cardiovascular diseases and mortality. Cardiac troponin levels are heritable, but their genetic architecture remains elusive. Methods: We conducted a transethnic genome-wide association analysis on high-sensitivity cTnT (cardiac troponin T; hs-cTnT) and high-sensitivity cTnI (cardiac troponin I; hs-cTnI) levels in 24 617 and 14 336 participants free of coronary heart disease and heart failure from 6 popul...
Abstract
Cited 17 times since 2021 (4.5 per year)
source: EuropePMC
Molecular therapy. Nucleic acids,
Volume 26, 4 1 2021, Pages 1228-1239
Inhibition of microRNA-494-3p activates Wnt signaling and reduces proinflammatory macrophage polarization in atherosclerosis.
van Ingen E, van Ingen E, Foks AC, Woudenberg T, van der Bent ML, de Jong A, Hohensinner PJ, Wojta J, Bot I, Quax PHA, Nossent AY
We have previously shown that treatment with third-generation antisense oligonucleotides against miR-494-3p (3GA-494) reduces atherosclerotic plaque progression and stabilizes lesions, both in early and established plaques, with reduced macrophage content in established plaques. Within the plaque, different subtypes of macrophages are present. Here, we aimed to investigate whether miR-494-3p directly influences macrophage polarization and activation. Human macrophages were polarized into either...
Abstract
Cited 22 times since 2021 (5.8 per year)
source: EuropePMC
Stroke,
Volume 52, Issue 12, 4 1 2021, Pages 3978-3986
Risk, Clinical Course, and Outcome of Ischemic Stroke in Patients Hospitalized With COVID-19: A Multicenter Cohort Study.
Sluis WM, Linschoten M, Buijs JE, Biesbroek JM, den Hertog HM, Ribbers T, Nieuwkamp DJ, van Houwelingen RC, Dias A, van Uden IWM, Kerklaan JP, Bienfait HP, Vermeer SE, de Jong SW, Ali M, Wermer MJH, de Graaf MT, Brouwers PJAM, Asselbergs FW, Kappelle LJ, van der Worp HB, Algra AM, CAPACITY-COVID Collaborative Consortium*
Background and purpose: The frequency of ischemic stroke in patients with coronavirus disease 2019 (COVID-19) varies in the current literature, and risk factors are unknown. We assessed the incidence, risk factors, and outcomes of acute ischemic stroke in hospitalized patients with COVID-19. Methods: We included patients with a laboratory-confirmed SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) infection admitted in 16 Dutch hospitals participating in the international CAPACITY-COV...
Abstract
Cited 17 times since 2021 (4.5 per year)
source: EuropePMC
BMC medicine,
Volume 19, Issue 1, 3 1 2021, Pages 266
Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling.
van Vliet NA, Bos MM, Thesing CS, Chaker L, Pietzner M, Houtman E, Neville MJ, Li-Gao R, Trompet S, Mustafa R, Ahmadizar F, Beekman M, Bot M, Budde K, Christodoulides C, Dehghan A, Delles C, Elliott P, Evangelou M, Gao H, Ghanbari M, van Herwaarden AE, Ikram MA, Jaeger M, Jukema JW, Karaman I, Karpe F, Kloppenburg M, Meessen JMTA, Meulenbelt I, Milaneschi Y, Mooijaart SP, Mook-Kanamori DO, Netea MG, Netea-Maier RT, Peeters RP, Penninx BWJH, Sattar N, Slagboom PE, Suchiman HED, Völzke H, Willems van Dijk K, Noordam R, van Heemst D, BBMRI Metabolomics Consortium
Background: Observational studies suggest interconnections between thyroid status, metabolism, and risk of coronary artery disease (CAD), but causality remains to be proven. The present study aimed to investigate the potential causal relationship between thyroid status and cardiovascular disease and to characterize the metabolomic profile associated with thyroid status. Methods: Multi-cohort two-sample Mendelian randomization (MR) was performed utilizing genome-wide significant variants as instr...
Abstract
Cited 204 times since 2021 (53.7 per year)
source: EuropePMC
European urology,
Volume 81, Issue 1, 3 1 2021, Pages 95-103
The 2021 Updated European Association of Urology Guidelines on Metastatic Urothelial Carcinoma.
Cathomas R, Lorch A, Bruins HM, Compérat EM, Cowan NC, Efstathiou JA, Fietkau R, Gakis G, Hernández V, Espinós EL, Neuzillet Y, Ribal MJ, Rouanne M, Thalmann GN, van der Heijden AG, Veskimäe E, Alfred Witjes J, Milowsky MI, EAU Muscle-invasive, Metastatic Bladder Cancer Guidelines Panel
Context: Treatment of metastatic urothelial carcinoma is currently undergoing a rapid evolution. Objective: This overview presents the updated European Association of Urology (EAU) guidelines for metastatic urothelial carcinoma. Evidence acquisition: A comprehensive scoping exercise covering the topic of metastatic urothelial carcinoma is performed annually by the Guidelines Panel. Databases covered by the search included Medline, EMBASE, and the Cochrane Libraries, resulting in yearly guideline...
Abstract
Cited 30 times since 2021 (7.9 per year)
source: EuropePMC
JAMA otolaryngology-- head & neck surgery,
Volume 147, Issue 11, 1 1 2021, Pages 959-965
Persistent Postthyroidectomy Hypoparathyroidism in the Netherlands.
Loncar I, Noltes ME, Dickhoff C, Engelsman AF, Schepers A, Vriens MR, Bouvy ND, Kruijff S, van Ginhoven TM
Importance: Hypoparathyroidism is one of the most common complications after total or completion thyroidectomy. The reported incidence rate of hypoparathyroidism in the literature is highly variable. Data that provide a better understanding of the magnitude of this postoperative complication are warranted and can provide a stepping stone for further collaborations that aim to reduce complication rates and establish uniform treatment protocols. Objective: To evaluate the incidence of postoperativ...
Abstract
Cited 55 times since 2021 (14.5 per year)
source: EuropePMC
JAMA internal medicine,
Volume 181, Issue 11, 1 1 2021, Pages 1440-1450
Association of Thyroid Dysfunction With Cognitive Function: An Individual Participant Data Analysis.
van Vliet NA, van Heemst D, Almeida OP, Åsvold BO, Aubert CE, Bae JB, Barnes LE, Bauer DC, Blauw GJ, Brayne C, Cappola AR, Ceresini G, Comijs HC, Dartigues JF, Degryse JM, Dullaart RPF, van Eersel MEA, den Elzen WPJ, Ferrucci L, Fink HA, Flicker L, Grabe HJ, Han JW, Helmer C, Huisman M, Ikram MA, Imaizumi M, de Jongh RT, Jukema JW, Kim KW, Kuller LH, Lopez OL, Mooijaart SP, Moon JH, Moutzouri E, Nauck M, Parle J, Peeters RP, Samuels MH, Schmidt CO, Schminke U, Slagboom PE, Stordal E, Vaes B, Völzke H, Westendorp RGJ, Yamada M, Yeap BB, Rodondi N, Gussekloo J, Trompet S, Thyroid Studies Collaboration
Importance: In clinical guidelines, overt and subclinical thyroid dysfunction are mentioned as causal and treatable factors for cognitive decline. However, the scientific literature on these associations shows inconsistent findings. Objective: To assess cross-sectional and longitudinal associations of baseline thyroid dysfunction with cognitive function and dementia. Design, setting, and participants: This multicohort individual participant data analysis assessed 114 267 person-years (median, 1....
Abstract
Cited 8 times since 2021 (2.1 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 60, Issue 5, 1 1 2021, Pages 1014-1021
Right aortic arch forming a true vascular ring: a clinical review.
Biermann D, Holst T, Hüners I, Rickers C, Kehl T, Rüffer A, Sachweh JS, Hazekamp MG
Objectives: This review aims at presenting and summarizing the current state of literature on the presentation and surgical management of a right-sided aortic arch with a left-sided ligamentum forming a complete vascular ring around the oesophagus and trachea. Methods: A systematic database search for appropriate literature was conducted on PubMed/MEDLINE. Articles were considered relevant when providing details on the presentation, diagnosis and surgical treatment of this specific congenital ar...
Abstract
Cardiology and therapy,
Volume 11, Issue 1, 1 1 2021, Pages 81-92
Original Research: Long-Term Prognosis After ST-Elevation Myocardial Infarction in Patients with a Prior Cancer Diagnosis.
Heemelaar JC, Polomski EAS, Mertens BJA, Jukema JW, Schalij MJ, Antoni ML
Introduction: It is unknown how long-term prognosis after ST-elevation myocardial infarction (STEMI) in patients with a prior cancer diagnosis is impacted by cancer-related factors as diagnosis, stage, and treatment. We aimed to assess long-term survival trends after STEMI in this population to evaluate both cardiovascular and cancer-related drivers of prognosis over a follow-up period of 5 years. Methods: In this retrospective single-center cohort study, patients with a prior cancer diagnosis a...
Abstract
Cited 34 times since 2021 (8.9 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 78, Issue 19, 1 1 2021, Pages 1904-1918
AHA/ACC vs ESC Guidelines for Management of Adults With Congenital Heart Disease: JACC Guideline Comparison.
Egidy Assenza G, Krieger EV, Baumgartner H, Cupido B, Dimopoulos K, Louis C, Lubert AM, Stout KK, Valente AM, Zeppenfeld K, Opotowsky AR
The American Heart Association and American College of Cardiology published practice guidelines for the management of adult congenital heart disease in 2018 and the European Society of Cardiology published analogous guidelines in 2020. Although there are broad areas of consensus between the 2 documents, there are important differences that impact patient management. This review discusses key areas of agreement and disagreement between the 2 guidelines, with discussion of possible reasons for dis...
Abstract
Cited 15 times since 2021 (3.9 per year)
source: EuropePMC
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin,
Volume 26, Issue 45, 1 1 2021
Meta-analysis of the clinical performance of commercial SARS-CoV-2 nucleic acid and antibody tests up to 22 August 2020.
Van Walle I, Leitmeyer K, Broberg EK, European COVID-19 microbiological laboratories group
BackgroundReliable testing for SARS-CoV-2 is key for the management of the COVID-19 pandemic.AimWe estimate diagnostic accuracy for nucleic acid and antibody tests 5 months into the COVID-19 pandemic, and compare with manufacturer-reported accuracy.MethodsWe reviewed the clinical performance of SARS-CoV-2 nucleic acid and antibody tests based on 93,757 test results from 151 published studies and 20,205 new test results from 12 countries in the European Union and European Economic Area (EU/EEA).R...
Abstract
Cited 4 times since 2021 (1.1 per year)
source: EuropePMC
Academic medicine :, journal of the Association of American Medical Colleges..,
Volume 96, Issue 11S, 1 1 2021, Pages S103-S108
A Vicious Cycle of Bias: Residents' Perceptions of Leadership in Health Care.
Ju M, van Schaik SM
Purpose: Despite growing interest in shared leadership models, autocratic physician leadership remains the norm in health care. Stereotype and bias limit leadership by members of other professions. Furthermore, traditional views of effective clinical leadership emphasize agentic behaviors associated with male gender. To shift the prototypical concept of a leader from a male physician to a more inclusive prototype, a better understanding of prototype formation is needed. This study examines leade...
Abstract
Cited 34 times since 2021 (8.9 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 78, Issue 22, 1 1 2021, Pages 2131-2143
Contemporary Management of Severe Symptomatic Aortic Stenosis.
Eugène M, Duchnowski P, Prendergast B, Wendler O, Laroche C, Monin JL, Jobic Y, Popescu BA, Bax JJ, Vahanian A, Iung B, EORP VHD II Registry Investigators Group
Background: There were gaps between guidelines and practice when surgery was the only treatment for aortic stenosis (AS). Objectives: This study analyzed the decision to intervene in patients with severe AS in the EORP VHD (EURObservational Research Programme Valvular Heart Disease) II survey. Methods: Among 2,152 patients with severe AS, 1,271 patients with high-gradient AS who were symptomatic fulfilled a Class I recommendation for intervention according to the 2012 European Society of Cardiol...
Abstract
Cited 1 times since 2021 (0.3 per year)
source: EuropePMC
Current opinion in urology,
Volume 31, Issue 6, 1 1 2021, Pages 580-585
Orthotopic urinary diversions after radical cystectomy for bladder cancer: lessons learned last decade.
Janssen GWB, Ramkumar RR, Lee BH, van der Heijden AG
Purpose of review: Orthotopic urinary diversion (OUD), or neobladder, is believed to be the gold standard for surgical bladder reconstruction following radical cystectomy though it is performed far less often than ileal conduits. As both a continent and intracavitary diversion, OUDs offer unique advantages for patients. Their utilization has decreased overall though, especially with the advent of robotic surgery. In this review, we will cover patient selection for OUD, functional outcomes (i.e.,...
Abstract
Cited 2 times since 2021 (0.5 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 14, Issue 11, 1 1 2021, Pages 2272-2274
The Power of Large Clinical Databases and Registries in our Understanding of Cardiovascular Diseases.
Bax JJ, Chandrashekhar Y
Abstract
Cited 93 times since 2021 (24.4 per year)
source: EuropePMC
JAMA cardiology,
Volume 6, Issue 11, 1 1 2021, Pages 1257-1266
Association of Statin Treatment With Progression of Coronary Atherosclerotic Plaque Composition.
van Rosendael AR, van den Hoogen IJ, Gianni U, Ma X, Tantawy SW, Bax AM, Lu Y, Andreini D, Al-Mallah MH, Budoff MJ, Cademartiri F, Chinnaiyan K, Choi JH, Conte E, Marques H, de Araújo Gonçalves P, Gottlieb I, Hadamitzky M, Leipsic JA, Maffei E, Pontone G, Shin S, Kim YJ, Lee BK, Chun EJ, Sung JM, Lee SE, Virmani R, Samady H, Sato Y, Stone PH, Berman DS, Narula J, Blankstein R, Min JK, Lin FY, Shaw LJ, Bax JJ, Chang HJ
Importance: The density of atherosclerotic plaque forms the basis for categorizing calcified and noncalcified morphology of plaques. Objective: To assess whether alterations in plaque across a range of density measurements provide a more detailed understanding of atherosclerotic disease progression. Design, setting, and participants: This cohort study enrolled 857 patients who underwent serial coronary computed tomography angiography 2 or more years apart and had quantitative measurements of cor...
Abstract
Turkish archives of pediatrics,
Volume 56, Issue 6, 1 1 2021, Pages 654-656
Bicytopenia in a 15-Year-Old Adolescent: A Rare Side Effect of Fusidic Acid.
Şık N, Çakan Başerdem KA, Akyol Ş, Tüfekçi Ö, Yılmaz D, Duman M
Abstract
