9618 results
The Annals of thoracic surgery,
Volume 109, Issue 1, 3 1 2019, Pages 308-309
Reply.
Petrus AHJ, Klautz RJM, Braun J
Abstract
Cited 7 times since 2019 (1.1 per year)
source: EuropePMC
International journal of molecular sciences,
Volume 20, Issue 13, 2 1 2019, Pages E3251
Endothelial Colony Forming Cells as an Autologous Model to Study Endothelial Dysfunction in Patients with a Bicuspid Aortic Valve.
van de Pol V, Bons LR, Lodder K, Kurakula KB, Sanchez-Duffhues G, Siebelink HJ, Roos-Hesselink JW, DeRuiter MC, Goumans MJ
Bicuspid aortic valve (BAV), the most common congenital heart defect, is associated with an increased prevalence of aortic dilation, aortic rupture and aortic valve calcification. Endothelial cells (ECs) play a major role in vessel wall integrity. Little is known regarding EC function in BAV patients due to lack of patient derived primary ECs. Endothelial colony forming cells (ECFCs) have been reported to be a valid surrogate model for several cardiovascular pathologies, thereby facilitating an...
Abstract
Cited 10 times since 2019 (1.6 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 26, 1 1 2019, Pages 2170
Tornado-like flow in the Fontan circulation: insights from quantification and visualization of viscous energy loss rate using 4D flow MRI.
Rijnberg FM, van Assen HC, Hazekamp MG, Roest AAW
Abstract
Cited 39 times since 2019 (6.4 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 21, Issue 7, 1 1 2019, Pages 993-994
EHRA White Paper: knowledge gaps in arrhythmia management-status 2019.
Goette A, Auricchio A, Boriani G, Braunschweig F, Terradellas JB, Burri H, Camm AJ, Crijns H, Dagres N, Deharo JC, Dobrev D, Hatala R, Hindricks G, Hohnloser SH, Leclercq C, Lewalter T, Lip GYH, Merino JL, Mont L, Prinzen F, Proclemer A, Pürerfellner H, Savelieva I, Schilling R, Steffel J, van Gelder IC, Zeppenfeld K, Zupan I, Heidbüchel H, ESC Scientific Document Group
Clinicians accept that there are many unknowns when we make diagnostic and therapeutic decisions. Acceptance of uncertainty is essential for the pursuit of the profession: bedside decisions must often be made on the basis of incomplete evidence. Over the years, physicians sometimes even do not realize anymore which the fundamental gaps in our knowledge are. As clinical scientists, however, we have to halt and consider what we do not know yet, and how we can move forward addressing those unknowns...
Abstract
Cited 13 times since 2019 (2.1 per year)
source: EuropePMC
Nature genetics,
Volume 51, Issue 7, 1 1 2019, Pages 1192-1193
Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
Malik R, Chauhan G, Traylor M, Sargurupremraj M, Okada Y, Mishra A, Rutten-Jacobs L, Giese AK, van der Laan SW, Gretarsdottir S, Anderson CD, Chong M, Adams HHH, Ago T, Almgren P, Amouyel P, Ay H, Bartz TM, Benavente OR, Bevan S, Boncoraglio GB, Brown RD, Butterworth AS, Carrera C, Carty CL, Chasman DI, Chen WM, Cole JW, Correa A, Cotlarciuc I, Cruchaga C, Danesh J, de Bakker PIW, DeStefano AL, den Hoed M, Duan Q, Engelter ST, Falcone GJ, Gottesman RF, Grewal RP, Gudnason V, Gustafsson S, Haessler J, Harris TB, Hassan A, Havulinna AS, Heckbert SR, Holliday EG, Howard G, Hsu FC, Hyacinth HI, Ikram MA, Ingelsson E, Irvin MR, Jian X, Jiménez-Conde J, Johnson JA, Jukema JW, Kanai M, Keene KL, Kissela BM, Kleindorfer DO, Kooperberg C, Kubo M, Lange LA, Langefeld CD, Langenberg C, Launer LJ, Lee JM, Lemmens R, Leys D, Lewis CM, Lin WY, Lindgren AG, Lorentzen E, Magnusson PK, Maguire J, Manichaikul A, McArdle PF, Meschia JF, Mitchell BD, Mosley TH, Nalls MA, Ninomiya T, O'Donnell MJ, Psaty BM, Pulit SL, Rannikmäe K,
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Abstract
Cited 11 times since 2019 (1.8 per year)
source: EuropePMC
BMJ open,
Volume 9, Issue 7, 1 1 2019, Pages e029254
An observational study on survival rates of patients with out-of-hospital cardiac arrest in the Netherlands after improving the 'chain of survival'.
de Visser M, Bosch J, Bootsma M, Cannegieter S, van Dijk A, Heringhaus C, de Nooij J, Terpstra N, Peschanski N, Burggraaf K
Objectives: To evaluate the impact of implemented procedures for out-of-hospital cardiac arrests (OHCAs) by determining patient outcome defined as the percentage return of spontaneous circulation at arrival at the emergency department, and 3-month and 1-year-survival rates. Design: Observational study. Setting: Primary emergency medical care consisting of Advanced Life Support is given by ambulance nurses and secondary care by hospitals within the mid-western part of the Netherlands covering 750...
Abstract
The Journal of rheumatology,
Volume 46, Issue 9, 1 1 2019, Pages 1244-1245
Degree of Vasculopathy in Systemic Sclerosis Patients with Anti-U3RNP Antibody Indicates Need for Extensive Cardiopulmonary Screening.
VAN Leeuwen NM, Boonstra M, Ajmone Marsan N, Ninaber MK, Huizinga TWJ, DE Vries-Bouwstra JK
Abstract
Cited 36 times since 2019 (5.9 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 27, 1 1 2019, Pages 2206-2214
Impact of recurrent mitral regurgitation after mitral valve repair for functional mitral regurgitation: long-term analysis of competing outcomes.
Petrus AHJ, Dekkers OM, Tops LF, Timmer E, Klautz RJM, Braun J
Aims: Recurrent mitral regurgitation (MR) has been reported after mitral valve repair for functional MR. However, the impact of recurrent MR on long-term survival remains poorly defined. In the present study, mortality-adjusted recurrent MR rates, the clinical impact of recurrent MR and its determinants were studied in patients after mitral valve repair with revascularization for functional MR in the setting of ischaemic heart disease. Methods and results: Long-term clinical and echocardiographi...
Abstract
Cited 55 times since 2019 (9 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 26, 1 1 2019, Pages 2142-2151
Cardiac arrest in takotsubo syndrome: results from the InterTAK Registry.
Gili S, Cammann VL, Schlossbauer SA, Kato K, D'Ascenzo F, Di Vece D, Jurisic S, Micek J, Obeid S, Bacchi B, Szawan KA, Famos F, Sarcon A, Levinson R, Ding KJ, Seifert B, Lenoir O, Bossone E, Citro R, Franke J, Napp LC, Jaguszewski M, Noutsias M, Münzel T, Knorr M, Heiner S, Katus HA, Burgdorf C, Schunkert H, Thiele H, Bauersachs J, Tschöpe C, Pieske BM, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Hasenfuß G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Empen K, Felix SB, Delmas C, Lairez O, El-Battrawy I, Akin I, Borggrefe M, Gilyarova E, Shilova A, Gilyarov M, Horowitz JD, Kozel M, Tousek P, Widimský P, Winchester DE, Ukena C, Gaita F, Di Mario C, Wischnewsky MB, Bax JJ, Prasad A, Böhm M, Ruschitzka F, Lüscher TF, Ghadri JR, Templin C
Aims: We aimed to evaluate the frequency, clinical features, and prognostic implications of cardiac arrest (CA) in takotsubo syndrome (TTS). Methods and results: We reviewed the records of patients with CA and known heart rhythm from the International Takotsubo Registry. The main outcomes were 60-day and 5-year mortality. In addition, predictors of mortality and predictors of CA during the acute TTS phase were assessed. Of 2098 patients, 103 patients with CA and known heart rhythm during CA were...
Abstract
Cited 116 times since 2019 (18.9 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 74, Issue 4, 1 1 2019, Pages 550-563
Staging Cardiac Damage in Patients With Asymptomatic Aortic Valve Stenosis.
Tastet L, Tribouilloy C, Maréchaux S, Vollema EM, Delgado V, Salaun E, Shen M, Capoulade R, Clavel MA, Arsenault M, Bédard É, Bernier M, Beaudoin J, Narula J, Lancellotti P, Bax JJ, Généreux P, Pibarot P
Background: The optimal timing of intervention in patients with asymptomatic severe aortic stenosis (AS) remains controversial. Objectives: This multicenter study sought to test and validate the prognostic value of the staging of cardiac damage in patients with asymptomatic moderate to severe AS. Methods: This study retrospectively analyzed the clinical, Doppler echocardiographic, and outcome data that were prospectively collected in 735 asymptomatic patients (71 ± 14 years of age; 60% men) with...
Abstract
Cited 8 times since 2019 (1.3 per year)
source: EuropePMC
PloS one,
Volume 14, Issue 7, 1 1 2019, Pages e0218676
The modulation of facial mimicry by attachment tendencies and their underlying affiliation motives in 3-year-olds: An EMG study.
Vacaru SV, van Schaik JE, Hunnius S
From early in life, facial mimicry represents an important example of implicit non-verbal communication. Facial mimicry is conceived of as the automatic tendency to mimic another person's facial expressions and is thought to serve as a social glue among interaction partners. Although in adults mimicry has been shown to be moderated by the social context and one's needs to affiliate with others, evidence from behavioural mimicry studies suggest that 3-year-olds do not yet show sensitivi...
Abstract
Cited 6 times since 2019 (1 per year)
source: EuropePMC
The Journal of infectious diseases,
Volume 220, Issue 4, 1 1 2019, Pages 624-634
Chemokine Receptor 7 Is Essential for Coxiella burnetii Whole-Cell Vaccine-Induced Cellular Immunity but Dispensable for Vaccine-Mediated Protective Immunity.
Chen C, van Schaik EJ, Gregory AE, Vigil A, Felgner PL, Hendrix LR, Faris R, Samuel JE
Background: Protective immunity against Coxiella burnetii infection is conferred by vaccination with virulent (PI-WCV), but not avirulent (PII-WCV) whole-cell inactivated bacterium. The only well-characterized antigenic difference between virulent and avirulent C. burnetii is they have smooth and rough lipopolysaccharide (LPS), respectively. Methods: Mice were vaccinated with PI-WCV and PII-WCV. Humoral and cellular responses were evaluated using protein chip microarrays and ELISpots, respective...
Abstract
Cited 26 times since 2019 (4.2 per year)
source: EuropePMC
Academic medicine : journal of the Association of American Medical Colleges,
Volume 94, Issue 7, 1 1 2019, Pages 975-982
Exemplary Learning Environments for the Health Professions: A Vision.
van Schaik SM, Reeves SA, Headrick LA
In this article, the authors propose a vision for exemplary learning environments in which everyone involved in health professions education and health care collaborates toward optimal health for individuals, populations, and communities. Learning environments in the health professions can be conceptualized as complex adaptive systems, defined as a collection of individual agents whose actions are interconnected and follow a set of shared "simple rules." Using principles from complex a...
Abstract
Cited 8 times since 2019 (1.3 per year)
source: EuropePMC
The American journal of cardiology,
Volume 124, Issue 6, 1 1 2019, Pages 892-898
Defining Subclinical Myocardial Dysfunction and Implications for Patients With Diabetes Mellitus and Preserved Ejection Fraction.
Ng ACT, Bertini M, Ewe SH, van der Velde ET, Leung DY, Delgado V, Bax JJ
Left ventricular (LV) global longitudinal strain (GLS) can detect subclinical myocardial systolic dysfunction in individuals with diabetes. The present study investigates the clinical usefulness and incremental net benefit of identifying subclinical myocardial systolic dysfunction in individuals with diabetes. A cohort of 397 type 2 diabetic individuals was followed up for the occurrence of all-cause mortality. Clinical and echocardiographic data of diabetic patients were assessed retrospectivel...
Abstract
Cited 4 times since 2019 (0.7 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 56, Issue 1, 1 1 2019, Pages 210-212
Management of incidentally diagnosed pulmonary artery dissection in patients with pulmonary arterial hypertension.
Nuche J, Montero Cabezas JM, Alonso Charterina S, Escribano Subías P
Pulmonary artery dissection is a rare entity, usually discovered post-mortem. In recent years, reported cases of living patients with a pulmonary artery dissection are growing and represent a challenging situation for clinicians.
Abstract
Cited 6 times since 2019 (1 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 27, 1 1 2019, Pages 2203-2205
Characterizing mitral regurgitation in a contemporary population: prognostic implications.
Delgado V, Ajmone Marsan N, Bax JJ
Abstract
Cited 59 times since 2019 (9.6 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 74, Issue 4, 1 1 2019, Pages 538-549
Staging Cardiac Damage in Patients With Symptomatic Aortic Valve Stenosis.
Vollema EM, Amanullah MR, Ng ACT, van der Bijl P, Prevedello F, Sin YK, Prihadi EA, Marsan NA, Ding ZP, Généreux P, Pibarot P, Leon MB, Narula J, Ewe SH, Delgado V, Bax JJ
Background: In severe aortic stenosis (AS), patients often show extra-aortic valvular injury. Recently, a new staging system for severe AS has been proposed on the basis of the extent of cardiac damage. Objectives: The present study evaluated the prevalence and prognostic impact of these different stages of cardiac damage in a large, real-world, multicenter cohort of symptomatic severe AS patients. Methods: From the ongoing registries from 2 academic institutions, a total of 1,189 symptomatic se...
Abstract
Cited 61 times since 2019 (9.9 per year)
source: EuropePMC
JAMA cardiology,
Volume 4, Issue 7, 1 1 2019, Pages 613-619
Effect of the PCSK9 Inhibitor Evolocumab on Total Cardiovascular Events in Patients With Cardiovascular Disease: A Prespecified Analysis From the FOURIER Trial.
Murphy SA, Pedersen TR, Gaciong ZA, Ceska R, Ezhov MV, Connolly DL, Jukema JW, Toth K, Tikkanen MJ, Im K, Wiviott SD, Kurtz CE, Honarpour N, Giugliano RP, Keech AC, Sever PS, Sabatine MS
Importance: The PCSK9 inhibitor evolocumab reduced low-density lipoprotein cholesterol and first cardiovascular events in the Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk (FOURIER) trial, but patients remain at high risk of recurrent cardiovascular events. Objective: To evaluate the effect of evolocumab on total cardiovascular events, given the importance of total number of cardiovascular events to patients, clinicians, and health economists. Desi...
Abstract
Cited 17 times since 2019 (2.8 per year)
source: EuropePMC
BMC medical genetics,
Volume 20, Issue 1, 1 1 2019, Pages 117
Overexpression of MicroRNA-148b-3p stimulates osteogenesis of human bone marrow-derived mesenchymal stem cells: the role of MicroRNA-148b-3p in osteogenesis.
Mollazadeh S, Fazly Bazzaz BS, Neshati V, de Vries AAF, Naderi-Meshkin H, Mojarad M, Mirahmadi M, Neshati Z, Kerachian MA
Background: Mesenchymal stem cells (MSCs) are attractive choices in regenerative medicine and can be genetically modified to obtain better results in therapeutics. Bone development and metabolism are controlled by various factors including microRNAs (miRs) interference, which are small non-coding endogenous RNAs. Methods: In the current study, the effects of forced miR-148b expression was evaluated on osteogenic activity. Human bone marrow-derived mesenchymal stem cells (BM-MSCs) were transduced...
Abstract
Cited 20 times since 2019 (3.3 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 20, Issue 7, 1 1 2019, Pages 740-748
Determinants and prognostic implications of left ventricular mechanical dispersion in aortic stenosis.
Prihadi EA, Vollema EM, Ng ACT, Ajmone Marsan N, Bax JJ, Delgado V
Aims: The present study aimed at investigating the association between left ventricular (LV) mechanical dispersion measured with speckle tracking echocardiography and severity of aortic stenosis (AS) and its impact on prognosis. Methods and results: This retrospective study included 630 patients [age 72 (62-78) years, 61.4% men] with various grades of AS (mild AS, 19.8%; moderate AS, 37.0%; severe AS, 43.2%). LV mechanical dispersion (defined as standard deviation of time from Q/R on electrocard...
Abstract
