Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
9618 results
Cited 133 times since 2019 (20.5 per year) source: EuropePMC
JACC. Cardiovascular imaging, Volume 12, Issue 3, 1 1 2019, Pages 491-499 Morphologic Types of Tricuspid Regurgitation: Characteristics and Prognostic Implications. Prihadi EA, Delgado V, Leon MB, Enriquez-Sarano M, Topilsky Y, Bax JJ
Tricuspid regurgitation (TR) is classified according to different morphologic types based on the underlying mechanisms: primary, secondary, and isolated TR. Primary TR is caused by an anatomical abnormality of the tricuspid valve apparatus. Secondary TR is caused by dilation of the tricuspid valve annulus, related to right ventricular (RV), or right atrial remodeling and increased RV pressures (often secondary to left-sided heart disease). Isolated TR can exist in patients without increased RV p... Abstract
European heart journal, Volume 40, Issue 11, 1 1 2019, Pages 867 Dr Shahbudin H. Rahimtoola: the mentor. Bax JJ
Cited 5 times since 2019 (0.8 per year) source: EuropePMC
Advances in physiology education, Volume 43, Issue 1, 1 1 2019, Pages 7-14 Informing the uninformed: a multitier approach to uncover students' misconceptions on cardiovascular physiology. Versteeg M, Wijnen-Meijer M, Steendijk P
Misconceptions about physiology are a major threat to accurate scientific and clinical reasoning in medical education. Awareness is often mentioned as a prerequisite to achieve conceptual understanding; however, students are frequently unaware of their incorrect understanding. We explored the multitier approach as a tool to obtain insight into students' awareness and misconceptions regarding cardiovascular physiology. Biomedical sciences students ( N = 81) participated in a diagnostic multi... Abstract
Cited 19 times since 2019 (2.9 per year) source: EuropePMC
Lancet (London, England), Volume 393, Issue 10175, 1 1 2019, Pages 1056-1070 Multimodality imaging in ischaemic heart failure. Bax JJ, Di Carli M, Narula J, Delgado V
In heart failure, extensive evaluation with modern non-invasive imaging modalities is needed to assess causes, pathophysiology, and haemodynamics, to determine prognosis and consider therapeutic options. This systematic evaluation includes a stepwise assessment of left ventricular size and function, the presence and severity of coronary artery disease, mitral regurgitation, pulmonary hypertension, right ventricular dilation and dysfunction, and tricuspid regurgitation. Based on this imaging-deri... Abstract
Cited 19 times since 2019 (2.9 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 27, Issue 3, 1 1 2019, Pages 127-133 Frailty score for elderly patients is associated with short-term clinical outcomes in patients with ST-segment elevated myocardial infarction treated with primary percutaneous coronary intervention. Hermans MPJ, Eindhoven DC, van Winden LAM, de Grooth GJ, Blauw GJ, Muller M, Schalij MJ
Objective: Consistent with the aging population in the Western world, there is a growing number of elderly patients with ST-segment elevation myocardial infarction (STEMI). Primary percutaneous coronary intervention (PCI) is the recommended reperfusion strategy in elderly patients; risk models to determine which of these patients are prone to have poor clinical outcomes are, however, essential. The purpose of this study was to assess the association between frailty and short-term mortality and P... Abstract
Cited 113 times since 2019 (17.5 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 12, Issue 3, 1 1 2019, Pages e008666 Prognostic Implications of Right Ventricular Free Wall Longitudinal Strain in Patients With Significant Functional Tricuspid Regurgitation. Prihadi EA, van der Bijl P, Dietz M, Abou R, Vollema EM, Marsan NA, Delgado V, Bax JJ
Background In patients with significant functional tricuspid regurgitation, timely detection of right ventricular (RV) dysfunction with conventional 2-dimensional echocardiography is challenging, whereas speckle-tracking echocardiography RV free wall longitudinal strain has been proposed as better prognosticator. We evaluated the prevalence and prognostic value of impaired RV free wall longitudinal strain in patients with significant functional tricuspid regurgitation, in comparison with tricusp... Abstract
Cited 8 times since 2019 (1.2 per year) source: EuropePMC
Annals of cardiothoracic surgery, Volume 8, Issue 2, 1 1 2019, Pages 202-209 Training in robotic thoracic surgery-the European way. Shahin GMM, Brandon Bravo Bruinsma GJ, Stamenkovic S, Cuesta MA
The increasing demand for robot-assisted thoracic surgery (RATS) in Europe requires a structured and standardized training module. Until now, Intuitive Surgical Inc. (Sunnyvale, CA, USA) has delivered the only available robotic surgery platform. Although the training program that is organized by Intuitive is divided in an initial and an advanced course, the success of the training depends on many external factors. Until now the training focused on experienced thoracic surgeons. The aim of this a... Abstract
Cited 7 times since 2019 (1.1 per year) source: EuropePMC
Journal of dairy science, Volume 102, Issue 5, 1 1 2019, Pages 4441-4451 Intramammary antimicrobial treatment of subclinical mastitis and cow performance later in lactation. van den Borne BHP, van Schaik G, Lam TJGM, Nielen M, Frankena K
The aim of this study was to evaluate long-term therapeutic effects of antimicrobial treatment of recently acquired subclinical mastitis (RASCM) during lactation. Quarter-level clinical mastitis (CM) follow-up, composite somatic cell counts (SCC), and cow-level milk yield later in lactation were evaluated using follow-up data from 2 previously published linked randomized field trials. The first trial randomly assigned antimicrobial treatment with any intramammary product or negative control to c... Abstract
Cited 12 times since 2019 (1.9 per year) source: EuropePMC
Journal of the peripheral nervous system : JPNS, Volume 24, Issue 1, 1 1 2019, Pages 72-79 Restabilization treatment after intravenous immunoglobulin withdrawal in chronic inflammatory demyelinating polyneuropathy: Results from the pre-randomization phase of the Polyneuropathy And Treatment with Hizentra study. Mielke O, Bril V, Cornblath DR, Lawo JP, van Geloven N, Hartung HP, Lewis RA, Merkies ISJ, Sobue G, Durn B, Shebl A, van Schaik IN, PATH study group
In patients with chronic inflammatory demyelinating polyneuropathy (CIDP), intravenous immunoglobulin (IVIG) is recommended to be periodically reduced to assess the need for ongoing therapy. However, little is known about the effectiveness of restabilization with IVIG in patients who worsen after IVIG withdrawal. In the Polyneuropathy And Treatment with Hizentra (PATH) study, the pre-randomization period included sudden stopping of IVIG followed by 12 weeks of observation. Those deteriorating we... Abstract
Cited 10 times since 2019 (1.5 per year) source: EuropePMC
The British journal of ophthalmology, Volume 105, Issue 9, 1 1 2019, Pages 1286-1288 Validation of a model for the prediction of retinopathy in persons with type 1 diabetes. Schreur V, Ng H, Nijpels G, Stefánsson E, Tack CJ, Klevering BJ, de Jong EK, Hoyng CB, Keunen JEE, van der Heijden AA
Background/aim: To validate a previously developed model for prediction of diabetic retinopathy (DR) for personalised retinopathy screening in persons with type 1 diabetes. Methods: Retrospective medical data of persons with type 1 diabetes treated in an academic hospital setting were used for analysis. Sight-threatening retinopathy (STR) was defined as the presence of severe non-proliferative DR, proliferative DR or macular oedema. The presence and grade of retinopathy, onset of diabetes, systo... Abstract
Cited 452 times since 2019 (69.8 per year) source: EuropePMC
Circulation, Volume 139, Issue 12, 1 1 2019, Pages 1483-1492 Lipoprotein(a), PCSK9 Inhibition, and Cardiovascular Risk. O'Donoghue ML, Fazio S, Giugliano RP, Stroes ESG, Kanevsky E, Gouni-Berthold I, Im K, Lira Pineda A, Wasserman SM, Češka R, Ezhov MV, Jukema JW, Jensen HK, Tokgözoğlu SL, Mach F, Huber K, Sever PS, Keech AC, Pedersen TR, Sabatine MS
Background: Lipoprotein(a) [Lp(a)] may play a causal role in atherosclerosis. PCSK9 (proprotein convertase subtilisin/kexin 9) inhibitors have been shown to significantly reduce plasma Lp(a) concentration. However, the relationship between Lp(a) levels, PCSK9 inhibition, and cardiovascular risk reduction remains undefined. Methods: Lp(a) was measured in 25 096 patients in the FOURIER trial (Further Cardiovascular Outcomes Research with PCSK9 Inhibition in Subjects with Elevated Risk), a randomiz... Abstract
Cited 71 times since 2019 (11 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 21, Issue 3, 1 1 2019, Pages 366-376 Mechanisms of sex differences in atrial fibrillation: role of hormones and differences in electrophysiology, structure, function, and remodelling. Odening KE, Deiß S, Dilling-Boer D, Didenko M, Eriksson U, Nedios S, Ng FS, Roca Luque I, Sanchez Borque P, Vernooy K, Wijnmaalen AP, Yorgun H
Atrial fibrillation (AF) is the clinically most prevalent rhythm disorder with large impact on quality of life and increased risk for hospitalizations and mortality in both men and women. In recent years, knowledge regarding epidemiology, risk factors, and patho-physiological mechanisms of AF has greatly increased. Sex differences have been identified in the prevalence, clinical presentation, associated comorbidities, and therapy outcomes of AF. Although it is known that age-related prevalence o... Abstract
Cited 1 times since 2019 (0.2 per year) source: EuropePMC
Anatolian journal of cardiology, Volume 21, Issue 4, 1 1 2019, Pages 196-205 Demographics of patients with heart failure who were over 80 years old and were admitted to the cardiology clinics in Turkey. Gök G, Zoghi M, Sinan ÜY, Kılıç S, Tokgözoğlu L, Elder-Turk study investigators
Objective: Heart failure (HF) has a high prevalence and mortality rate in elderly patients; however, there are few studies that have focused on patients older than 80 years. The aim of this study is to describe and compare the age-specific demographics and clinical features of Turkish elderly patients with HF who were admitted to cardiology clinics. Methods: The Epidemiology of Cardiovascular Disease in Elderly Turkish population (ELDER-TURK) study was conducted in 73 centers in Turkey, and it r... Abstract
Cited 4 times since 2019 (0.6 per year) source: EuropePMC
Revista da Associacao Medica Brasileira (1992), Volume 65, Issue 3, 1 1 2019, Pages 446-451 Investigation of the effect of the virtual reality application on experimental pain severity in healthy. Karaman D, Erol F, Yılmaz D, Dikmen Y
Objective: This study aimed to investigate the effect of virtual reality application on experimental ischemic pain created with a blood pressure instrument in healthy volunteers. Methods: The research sample consisted of 172 volunteer adult students who conformed to the inclusion criteria. These individuals were assigned into an experimental (n=86) and a control group (n=86) by a simple randomization method. All individuals in the experimental and control groups wereexperimentally subjected to p... Abstract
Cited 15 times since 2019 (2.3 per year) source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 21, Issue 3, 1 1 2019, Pages 383-403 Advancement in cardiac imaging for treatment of ventricular arrhythmias in structural heart disease. Sramko M, Hoogendoorn JC, Glashan CA, Zeppenfeld K
Over the last decades, substrate-based approaches to ventricular tachycardia (VT) ablation have evolved into an important therapeutic option for patients with various structural heart diseases (SHD) and unmappable VT. The well-recognized limitations of conventional electroanatomical mapping (EAM) to delineate the complex 3D architecture of scar, and the potential capability of advanced cardiac imaging technologies to provide adjunctive information, have stimulated electrophysiologists to evaluat... Abstract
Cited 23 times since 2019 (3.6 per year) source: EuropePMC
Journal of the American Heart Association, Volume 8, Issue 6, 1 1 2019, Pages e007201 Coronary Calcium Characteristics as Predictors of Major Adverse Cardiac Events in Symptomatic Patients: Insights From the CORE 320 Multinational Study. Lo-Kioeng-Shioe MS, Vavere AL, Arbab-Zadeh A, Schuijf JD, Rochitte CE, Chen MY, Rief M, Kofoed KF, Clouse ME, Scholte AJ, Miller JM, Betoko A, Blaha MJ, Cox C, Deckers JW, Lima JAC
Background The predictive value of coronary artery calcium ( CAC ) has been widely studied; however, little is known about specific characteristics of CAC that are most predictive. We aimed to determine the independent associations of Agatston score, CAC volume, CAC area, CAC mass, and CAC density score with major adverse cardiac events in patients with suspected coronary artery disease. Methods and Results A total of 379 symptomatic participants, aged 45 to 85 years, referred for invasive coron... Abstract
Cited 19 times since 2019 (2.9 per year) source: EuropePMC
The Journal of rheumatology, Volume 46, Issue 4, 1 1 2019, Pages 405-415 Progression of Left Ventricular Myocardial Dysfunction in Systemic Sclerosis: A Speckle-tracking Strain Echocardiography Study. van Wijngaarden SE, Ben Said-Bouyeri S, Ninaber MK, Huizinga TWJ, Schalij MJ, Bax JJ, Delgado V, de Vries-Bouwstra JK, Marsan NA
Objective: Cardiac involvement is a main cause of mortality in systemic sclerosis (SSc). Its detection remains challenging using conventional echocardiography and little is known about its potential progression. This study assessed changes in cardiac performance over time in a prospective cohort of patients with SSc, including echocardiographic speckle-tracking strain analysis. Methods: The study included 234 patients with SSc [196 women, age 52 ± 14 yrs, 165 limited SSc, time since diagnosis 5.... Abstract
Cited 16 times since 2019 (2.5 per year) source: EuropePMC
Dento maxillo facial radiology, Volume 48, Issue 5, 28 4 2019, Pages 20180349 Comparison of the effectiveness of high resolution ultrasound with MRI in patients with temporomandibular joint dısorders. Yılmaz D, Kamburoğlu K
Objectives: To assess the effectiveness of a high resolution ultrasound for temporomandibular joint (TMJ) evaluation in comparison to MRI in patients with TMJ disorders. Methods: Our study comprised 50 patients (35 female and 15 male) with a mean age of 30.61. Clinical examination was performed. Bilateral imaging of TMJ was conducted by using a high-resolution ultrasound and 1.5 Tesla MR. Diagnostic accuracy of ultrasound was assessed for disc displacement and joint effusion in comparison to MRI... Abstract
Cited 31 times since 2019 (4.8 per year) source: EuropePMC
JACC. Clinical electrophysiology, Volume 5, Issue 4, 27 4 2019, Pages 480-489 Entropy as a Novel Measure of Myocardial Tissue Heterogeneity for Prediction of Ventricular Arrhythmias and Mortality in Post-Infarct Patients. Androulakis AFA, Zeppenfeld K, Paiman EHM, Piers SRD, Wijnmaalen AP, Siebelink HJ, Sramko M, Lamb HJ, van der Geest RJ, de Riva M, Tao Q
Objectives: This study proposed entropy as a new late gadolinium enhanced cardiac magnetic resonance-derived parameter to evaluate tissue inhomogeneity, independent of signal intensity thresholds. This study hypothesized that entropy within the scar is associated with ventricular arrhythmias (VAs), whereas entropy of the entire left ventricular (LV) myocardium is associated with mortality. Background: In patients after myocardial infarction, the heterogeneity of fibrosis determines the substrate... Abstract
Cited 10 times since 2019 (1.5 per year) source: EuropePMC
The American journal of cardiology, Volume 123, Issue 10, 22 4 2019, Pages 1722-1728 Comparison of Diagnostic Performance of Quantitative Flow Ratio in Patients With Versus Without Diabetes Mellitus. Smit JM, El Mahdiui M, van Rosendael AR, Jukema JW, Koning G, Reiber JHC, Bax JJ, Scholte AJ
Quantitative flow ratio (QFR) is a novel technique to calculate fractional flow reserve (FFR), without hyperemia induction or a pressure wire, and has not yet been validated in patients with diabetes mellitus (DM), who are at increased risk of coronary microvascular dysfunction. The purpose of our study was to compare the diagnostic performance of QFR in diabetic and nondiabetic patients. Patients who underwent invasive coronary angiography and subsequent invasive FFR measurement within 6 months... Abstract