9618 results
Cited 7 times since 2019 (1.1 per year)
source: EuropePMC
Journal of clinical tuberculosis and other mycobacterial diseases,
Volume 15, 25 4 2019, Pages 100089
Abnormalities suggestive of latent tuberculosis infection on chest radiography; how specific are they?
Uzorka JW, Kroft LJM, Bakker JA, van Zwet EW, Huisman E, Prins C, van der Zwan CJ, Ottenhoff THM, Arend SM
Background: Several radiological features have been reported in association with latent tuberculosis infection (LTBI) but it has not been studied which are specific. The aim of this study was to evaluate allegedly characteristic abnormalities on chest radiography (CXR) in patients with LTBI compared to uninfected controls. Methods: From 236 patients tested with QuantiFERON-TB Gold In-Tube (QFT), the CXR was re-evaluated in a blinded fashion for fibrotic scarring, (non-)calcified nodules and pleu...
Abstract
Cited 14 times since 2019 (2.1 per year)
source: EuropePMC
Diabetes care,
Volume 42, Issue 3, 24 4 2019, Pages 434-442
Type 2 Diabetes, but Not Insulin (Analog) Treatment, Is Associated With More Advanced Stages of Breast Cancer: A National Linkage of Cancer and Pharmacy Registries.
Overbeek JA, van Herk-Sukel MPP, Vissers PAJ, van der Heijden AAWA, Bronsveld HK, Herings RMC, Schmidt MK, Nijpels G
Objective: To investigate whether women with type 2 diabetes (T2D) develop a more advanced stage of breast cancer and whether treatment with insulin (analogs) is associated with specific breast cancer characteristics. Research design and methods: For this nested case-control study, women with breast cancer diagnosed in 2002-2014 were selected from the linked Netherlands Cancer Registry-PHARMO Database Network (N = 33,377). T2D was defined as receiving two or more dispensings of noninsulin blood...
Abstract
Cited 27 times since 2019 (4.1 per year)
source: EuropePMC
European journal of human genetics : EJHG,
Volume 27, Issue 6, 24 4 2019, Pages 952-962
Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.
van Setten J, Verweij N, Mbarek H, Niemeijer MN, Trompet S, Arking DE, Brody JA, Gandin I, Grarup N, Hall LM, Hemerich D, Lyytikäinen LP, Mei H, Müller-Nurasyid M, Prins BP, Robino A, Smith AV, Warren HR, Asselbergs FW, Boomsma DI, Caulfield MJ, Eijgelsheim M, Ford I, Hansen T, Harris TB, Heckbert SR, Hottenga JJ, Iorio A, Kors JA, Linneberg A, MacFarlane PW, Meitinger T, Nelson CP, Raitakari OT, Silva Aldana CT, Sinagra G, Sinner M, Soliman EZ, Stoll M, Uitterlinden A, van Duijn CM, Waldenberger M, Alonso A, Gasparini P, Gudnason V, Jamshidi Y, Kääb S, Kanters JK, Lehtimäki T, Munroe PB, Peters A, Samani NJ, Sotoodehnia N, Ulivi S, Wilson JG, de Geus EJC, Jukema JW, Stricker B, van der Harst P, de Bakker PIW, Isaacs A
Genome-wide association studies (GWAS) of quantitative electrocardiographic (ECG) traits in large consortia have identified more than 130 loci associated with QT interval, QRS duration, PR interval, and heart rate (RR interval). In the current study, we meta-analyzed genome-wide association results from 30,000 mostly Dutch samples on four ECG traits: PR interval, QRS duration, QT interval, and RR interval. SNP genotype data was imputed using the Genome of the Netherlands reference panel encompas...
Abstract
Cited 11 times since 2019 (1.7 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 42, Issue 3, 22 4 2019, Pages 313-320
Atrial fibrillation history impact on catheter ablation outcome. Findings from the ESC-EHRA Atrial Fibrillation Ablation Long-Term Registry.
Stabile G, Trines SA, Arbelo E, Dagres N, Brugada J, Kautzner J, Pokushalov E, Maggioni AP, Laroche C, Anselmino M, Beinart R, Traykov V, Blomström Lundqvist C, ESC-EHRA Atrial Fibrillation Ablation Long-Term Registry investigators
Background: Atrial fibrillation (AF) promotes atrial remodeling that in turn promotes AF perpetuation. The aim of our study is to investigate the impact of AF history length on 1-year outcome of AF catheter ablation in a cohort of patients enrolled in the Atrial Fibrillation Ablation Registry. Methods: We described the real-life clinical epidemiology, therapeutic strategies, and the short- and mid-term outcomes of 1948 patients (71.9% with paroxysmal AF) undergoing AF ablation procedures, strati...
Abstract
Cited 23 times since 2019 (3.5 per year)
source: EuropePMC
Frontiers in molecular biosciences,
Volume 5, 22 4 2019, Pages 120
Metabolic Alterations in Cardiopulmonary Vascular Dysfunction.
Smolders VF, Zodda E, Quax PHA, Carini M, Barberà JA, Thomson TM, Tura-Ceide O, Cascante M
Cardiovascular diseases (CVD) are the leading cause of death worldwide. CVD comprise a range of diseases affecting the functionality of the heart and blood vessels, including acute myocardial infarction (AMI) and pulmonary hypertension (PH). Despite their different causative mechanisms, both AMI and PH involve narrowed or blocked blood vessels, hypoxia, and tissue infarction. The endothelium plays a pivotal role in the development of CVD. Disruption of the normal homeostasis of endothelia, alter...
Abstract
Cited 8 times since 2019 (1.2 per year)
source: EuropePMC
Journal of the peripheral nervous system : JPNS,
Volume 24, Issue 1, 22 4 2019, Pages 34-38
International chronic inflammatory demyelinating polyneuropathy outcome study (ICOS): Protocol of a prospective observational cohort study on clinical and biological predictors of disease course and outcome.
Bunschoten C, Eftimov F, van der Pol WL, Jacobs BC, ICOS Consortium
Chronic inflammatory demyelinating polyneuropathy (CIDP) is a heterogeneous immune-mediated disorder with extensive variation in clinical presentation, electrophysiological phenotype, treatment response and long-term outcome. This heterogeneity may reflect the existence of distinct subtypes of CIDP with a different pathogenesis that require personalized treatment. The International CIDP Outcome Study (ICOS) is a prospective, observational, multicenter cohort study that aims to describe this vari...
Abstract
The Journal of thoracic and cardiovascular surgery,
Volume 157, Issue 6, 21 3 2019, Pages e371-e377
Endocardial/epicardial versus endocardial encircling cryoablation for ventricular tachycardia: A randomized trial.
van Huls van Taxis CF, Zeppenfeld K, Klautz RJ, Wijnmaalen AP
Abstract
Cited 2 times since 2019 (0.3 per year)
source: EuropePMC
EJVES short reports,
Volume 42, 21 3 2019, Pages 15-17
Repeat Rupture of a Giant Abdominal Aortic Aneurysm after EVAR.
Meekel JP, van Schaik TG, van Zeeland MLP, Yeung KK, Hoksbergen AWJ
Introduction: Ruptured abdominal aortic aneurysms (AAAs) are known to be associated with high fatal outcomes. Giant AAAs are often defined as having a maximum diameter over 13 cm. Large AAAs over 8 cm have demonstrated a yearly rupture rate of 30-50%, which explains the rarity of giant AAAs. Endovascular repair of ruptured AAAs (rAAAs) is increasingly advocated because of the shorter hospital stay and fewer post-operative complications. Nonetheless, outcomes regarding mortality and cost-effectiv...
Abstract
Cited 24 times since 2019 (3.6 per year)
source: EuropePMC
Cancer treatment reviews,
Volume 74, 19 3 2019, Pages 21-28
Drug-drug interactions in breast cancer patients treated with CDK4/6 inhibitors.
Fogli S, Del Re M, Curigliano G, van Schaik RH, Lancellotti P, Danesi R
CDK4/6 inhibitors are a new class of anticancer drugs used for the treatment of women with hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced or metastatic breast cancer with disease progression following endocrine therapy. Polypharmacy is a well-known problem in advanced cancer causing potential drug-drug interactions (DDIs), which, in turn, may limit the therapeutic value of CDK4/6 inhibitors. Therefore, understanding the mechanisms underlying potential DDIs...
Abstract
Cited 5 times since 2019 (0.8 per year)
source: EuropePMC
Frontiers in neuroscience,
Volume 12, 17 3 2019, Pages 1047
Investigation of Event-Based Surfaces for High-Speed Detection, Unsupervised Feature Extraction, and Object Recognition.
Afshar S, Hamilton TJ, Tapson J, van Schaik A, Cohen G
In this work, we investigate event-based feature extraction through a rigorous framework of testing. We test a hardware efficient variant of Spike Timing Dependent Plasticity (STDP) on a range of spatio-temporal kernels with different surface decaying methods, decay functions, receptive field sizes, feature numbers, and back end classifiers. This detailed investigation can provide helpful insights and rules of thumb for performance vs. complexity trade-offs in more generalized networks, especial...
Abstract
Cited 5 times since 2019 (0.8 per year)
source: EuropePMC
Epidemiology and psychiatric sciences,
Volume 29, 17 3 2019, Pages e13
Mental disorders and the risk of adult violent and psychological victimisation: a prospective, population-based study.
Christ C, Ten Have M, de Graaf R, van Schaik DJF, Kikkert MJ, Dekker JJM, Beekman ATF
Aims: Psychiatric patients are at increased risk to become victim of violence. It remains unknown whether subjects of the general population with mental disorders are at risk of victimisation as well. In addition, it remains unclear whether the risk of victimisation differs across specific disorders. This study aimed to determine whether a broad range of mood, anxiety and substance use disorders at baseline predict adult violent (physical and/or sexual) and psychological victimisation at 3-year...
Abstract
Cited 13 times since 2019 (2 per year)
source: EuropePMC
Scientific reports,
Volume 9, Issue 1, 17 3 2019, Pages 188
Predictors of objective cognitive impairment and subjective cognitive complaints in patients with Fabry disease.
Körver S, Geurtsen GJ, Hollak CEM, van Schaik IN, Longo MGF, Lima MR, Vedolin L, Dijkgraaf MGW, Langeveld M
This study investigates the relationship between objective cognitive impairment (OCI), subjective cognitive complaints and depressive symptoms in men and women with classical and non-classical Fabry disease (FD). Cognitive functioning was assessed using a neuropsychological test battery, subjective cognitive complaints using a structured interview and depressive symptoms using a depression scale (CESD). Eighty-one patients were included (mean age 44.5 ± 14.3, 35% men, 74% classical). Subjective...
Abstract
Cited 55 times since 2019 (8.3 per year)
source: EuropePMC
British journal of clinical pharmacology,
Volume 85, Issue 3, 17 3 2019, Pages 601-615
A population pharmacokinetic model to predict the individual starting dose of tacrolimus in adult renal transplant recipients.
Andrews LM, Hesselink DA, van Schaik RHN, van Gelder T, de Fijter JW, Lloberas N, Elens L, Moes DJAR, de Winter BCM
Aims: The aims of this study were to describe the pharmacokinetics of tacrolimus immediately after kidney transplantation, and to develop a clinical tool for selecting the best starting dose for each patient. Methods: Data on tacrolimus exposure were collected for the first 3 months following renal transplantation. A population pharmacokinetic analysis was conducted using nonlinear mixed-effects modelling. Demographic, clinical and genetic parameters were evaluated as covariates. Results: A tota...
Abstract
Cited 1 times since 2019 (0.2 per year)
source: EuropePMC
Nature communications,
Volume 10, Issue 1, 17 3 2019, Pages 382
Author Correction: Germline variation at 8q24 and prostate cancer risk in men of European ancestry.
Matejcic M, Saunders EJ, Dadaev T, Brook MN, Wang K, Sheng X, Olama AAA, Schumacher FR, Ingles SA, Govindasami K, Benlloch S, Berndt SI, Albanes D, Koutros S, Muir K, Stevens VL, Gapstur SM, Tangen CM, Batra J, Clements J, Gronberg H, Pashayan N, Schleutker J, Wolk A, West C, Mucci L, Kraft P, Cancel-Tassin G, Sorensen KD, Maehle L, Grindedal EM, Strom SS, Neal DE, Hamdy FC, Donovan JL, Travis RC, Hamilton RJ, Rosenstein B, Lu YJ, Giles GG, Kibel AS, Vega A, Bensen JT, Kogevinas M, Penney KL, Park JY, Stanford JL, Cybulski C, Nordestgaard BG, Brenner H, Maier C, Kim J, Teixeira MR, Neuhausen SL, De Ruyck K, Razack A, Newcomb LF, Lessel D, Kaneva R, Usmani N, Claessens F, Townsend PA, Gago-Dominguez M, Roobol MJ, Menegaux F, Khaw KT, Cannon-Albright LA, Pandha H, Thibodeau SN, Schaid DJ, PRACTICAL Consortium, Wiklund F, Chanock SJ, Easton DF, Eeles RA, Kote-Jarai Z, Conti DV, Haiman CA
The original version of this Article contained an error in the spelling of the author Manuela Gago-Dominguez, which was incorrectly given as Manuela G. Dominguez. This has now been corrected in both the PDF and HTML versions of the Article.
Abstract
Cited 116 times since 2019 (17.6 per year)
source: EuropePMC
The Journal of pathology,
Volume 247, Issue 3, 16 3 2019, Pages 333-346
Inflammation induces endothelial-to-mesenchymal transition and promotes vascular calcification through downregulation of BMPR2.
Sánchez-Duffhues G, García de Vinuesa A, van de Pol V, Geerts ME, de Vries MR, Janson SG, van Dam H, Lindeman JH, Goumans MJ, Ten Dijke P
Endothelial-to-mesenchymal transition (EndMT) has been unveiled as a common cause for a multitude of human pathologies, including cancer and cardiovascular disease. Vascular calcification is a risk factor for ischemic vascular disorders and slowing calcification may reduce mortality in affected patients. The absence of early biomarkers hampers the identification of patients at risk. EndMT and vascular calcification are induced upon cooperation between distinct stimuli, including inflammatory cyt...
Abstract
Cited 3 times since 2019 (0.5 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 12, Issue 8 Pt 1, 16 3 2019, Pages 1568-1571
Quantitative Evaluation of High-Risk Coronary Plaque by Coronary CTA and Subsequent Acute Coronary Events.
van Rosendael AR, Al'Aref SJ, Dwivedi A, Kim TS, Peña JM, Dunham PC, Kim YJ, Chinnaiyan K, Feuchtner G, Plank F, Berman DS, Shaw LJ, Chang HJ, Lin FY, Bax JJ, Narula J, Min JK
Abstract
Cited 61 times since 2019 (9.3 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 12, Issue 10, 16 3 2019, Pages 1987-1997
Superior Risk Stratification With Coronary Computed Tomography Angiography Using a Comprehensive Atherosclerotic Risk Score.
van Rosendael AR, Shaw LJ, Xie JX, Dimitriu-Leen AC, Smit JM, Scholte AJ, van Werkhoven JM, Callister TQ, DeLago A, Berman DS, Hadamitzky M, Hausleiter J, Al-Mallah MH, Budoff MJ, Kaufmann PA, Raff G, Chinnaiyan K, Cademartiri F, Maffei E, Villines TC, Kim YJ, Feuchtner G, Lin FY, Jones EC, Pontone G, Andreini D, Marques H, Rubinshtein R, Achenbach S, Dunning A, Gomez M, Hindoyan N, Gransar H, Leipsic J, Narula J, Min JK, Bax JJ
Objectives: This study was designed to assess the prognostic value of a new comprehensive coronary computed tomography angiography (CTA) score compared with the stenosis severity component of the Coronary Artery Disease-Reporting and Data System (CAD-RADS). Background: Current risk assessment with coronary CTA is mainly focused on maximal stenosis severity. Integration of plaque extent, location, and composition in a comprehensive model may improve risk stratification. Methods: A total of 2,134...
Abstract
Cited 67 times since 2019 (10.1 per year)
source: EuropePMC
Gastroenterology,
Volume 156, Issue 6, 12 2 2019, Pages 1788-1804.e13
Estrogen Activation of G-Protein-Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes.
Chaturantabut S, Shwartz A, Evason KJ, Cox AG, Labella K, Schepers AG, Yang S, Acuña M, Houvras Y, Mancio-Silva L, Romano S, Gorelick DA, Cohen DE, Zon LI, Bhatia SN, North TE, Goessling W
Background & aims: Patients with cirrhosis are at high risk for hepatocellular carcinoma (HCC) and often have increased serum levels of estrogen. It is not clear how estrogen promotes hepatic growth. We investigated the effects of estrogen on hepatocyte proliferation during zebrafish development, liver regeneration, and carcinogenesis. We also studied human hepatocytes and liver tissues. Methods: Zebrafish were exposed to selective modifiers of estrogen signaling at larval and adult stages....
Abstract
The Journal of thoracic and cardiovascular surgery,
Volume 157, Issue 5, 11 2 2019, Pages e249-e250
The devil is in the details, not the ring.
Tomšič A, Palmen M, Klautz RJM
Abstract
Cited 7 times since 2019 (1.1 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 42, Issue 2, 9 2 2019, Pages 208-215
Impact of left atrial box surface ratio on the recurrence after ablation for persistent atrial fibrillation.
Keçe F, Scholte AJ, de Riva M, Naruse Y, Watanabe M, Alizadeh Dehnavi R, Schalij MJ, Zeppenfeld K, Trines SA
Background: The posterior wall of the left atrium (LA) is a well-known substrate for atrial fibrillation (AF) maintenance. Isolation of the posterior wall between the pulmonary veins (box lesion) may improve ablation success. Box lesion surface area size varies depending on the individual anatomy. This retrospective study evaluates the influence of box lesion surface area as a ratio of total LA surface area (box surface ratio) on arrhythmia recurrence. Methods: Seventy consecutive patients with...
Abstract
