9618 results
Cited 80 times since 2019 (12.1 per year)
source: EuropePMC
Molecular psychiatry,
Volume 25, Issue 10, 7 1 2019, Pages 2392-2409
Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci.
Erzurumluoglu AM, Liu M, Jackson VE, Barnes DR, Datta G, Melbourne CA, Young R, Batini C, Surendran P, Jiang T, Adnan SD, Afaq S, Agrawal A, Altmaier E, Antoniou AC, Asselbergs FW, Baumbach C, Bierut L, Bertelsen S, Boehnke M, Bots ML, Brazel DM, Chambers JC, Chang-Claude J, Chen C, Corley J, Chou YL, David SP, de Boer RA, de Leeuw CA, Dennis JG, Dominiczak AF, Dunning AM, Easton DF, Eaton C, Elliott P, Evangelou E, Faul JD, Foroud T, Goate A, Gong J, Grabe HJ, Haessler J, Haiman C, Hallmans G, Hammerschlag AR, Harris SE, Hattersley A, Heath A, Hsu C, Iacono WG, Kanoni S, Kapoor M, Kaprio J, Kardia SL, Karpe F, Kontto J, Kooner JS, Kooperberg C, Kuulasmaa K, Laakso M, Lai D, Langenberg C, Le N, Lettre G, Loukola A, Luan J, Madden PAF, Mangino M, Marioni RE, Marouli E, Marten J, Martin NG, McGue M, Michailidou K, Mihailov E, Moayyeri A, Moitry M, Müller-Nurasyid M, Naheed A, Nauck M, Neville MJ, Nielsen SF, North K, Perola M, Pharoah PDP, Pistis G, Polderman TJ, Posthuma D, Poulter N, Qaiser B, Rasheed A, Rein
Smoking is a major heritable and modifiable risk factor for many diseases, including cancer, common respiratory disorders and cardiovascular diseases. Fourteen genetic loci have previously been associated with smoking behaviour-related traits. We tested up to 235,116 single nucleotide variants (SNVs) on the exome-array for association with smoking initiation, cigarettes per day, pack-years, and smoking cessation in a fixed effects meta-analysis of up to 61 studies (up to 346,813 participants). I...
Abstract
Cited 2 times since 2019 (0.3 per year)
source: EuropePMC
Frontiers in neuroscience,
Volume 12, 7 1 2019, Pages 991
Corrigendum: Large-Scale Neuromorphic Spiking Array Processors: A Quest to Mimic the Brain.
Thakur CS, Molin JL, Cauwenberghs G, Indiveri G, Kumar K, Qiao N, Schemmel J, Wang R, Chicca E, Hasler JO, Seo JS, Yu S, Cao Y, van Schaik A, Etienne-Cummings R
[This corrects the article DOI: 10.3389/fnins.2018.00891.].
Abstract
Cited 12 times since 2019 (1.8 per year)
source: EuropePMC
BMC public health,
Volume 19, Issue 1, 3 1 2019, Pages 9
Mapping of carbon monoxide related death risk in Turkey: a ten-year analysis based on news agency records.
Can G, Sayılı U, Aksu Sayman Ö, Kuyumcu ÖF, Yılmaz D, Esen E, Yurtseven E, Erginöz E
Background: Carbon-monoxide (CO) poisoning is a substantial cause of preventable mortality. In Turkey, no nationwide data are being collected nowadays. In our study, we aimed to assess the trend in deaths related to CO exposure in all provinces of Turkey in a 10-year period by using the records of a news agency which collects the news from the majority of the national newspapers, local newspapers and television channels. Methods: In this study, 27,881 news items that were released between Januar...
Abstract
Cited 29 times since 2019 (4.4 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 42, Issue 2, 2 1 2019, Pages 120-129
Remote monitoring of implantable cardioverter defibrillators: Patient experiences and preferences for follow-up.
Timmermans I, Meine M, Szendey I, Aring J, Romero Roldán J, van Erven L, Kahlert P, Zitron E, Mabo P, Denollet J, Versteeg H
Background: Patient satisfaction with remote patient monitoring (RPM) of implantable cardioverter defibrillators (ICDs) seems to be high, yet knowledge on long-term patient experiences is limited. The European REMOTE-CIED study explored patients' experiences with RPM, examined patient's preferences for ICD follow-up, and identified determinants of patient's preferences in the first 2 years postimplantation. Methods: European heart failure patients (N = 300; median age = 66 years [...
Abstract
Cited 1 times since 2019 (0.2 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 2, 1 1 2019, Pages 220
Severe ostial coronary lesions 10 years after Cabrol procedure: a mixed blessing technique?
Girgis HA, Kloet RW, Lamb HJ, Montero-Cabezas JM
Abstract
Cited 8 times since 2019 (1.2 per year)
source: EuropePMC
Journal of Alzheimer's disease : JAD,
Volume 67, Issue 1, 1 1 2019, Pages 279-289
Spatial QRS-T Angle and Cognitive Decline in Older Subjects.
Mahinrad S, Ferguson I, Macfarlane PW, Clark EN, Stott DJ, Ford I, Mooijaart SP, Trompet S, van Heemst D, Jukema JW, Sabayan B
Background: An abnormally wide spatial QRS-T angle on an ECG is a marker of heterogeneity in electrical activity of cardiac ventricles and is linked with cardiovascular events. Growing evidence suggests that cardiac dysfunction might signal future cognitive decline. Objective: In this study, we investigated whether spatial QRS-T angle associates with future cognitive decline in older subjects at high cardiovascular risk. Methods: We included 4,172 men and women (mean age 75.2±3.3 years) free of...
Abstract
Cited 1279 times since 2019 (192.7 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 3, 1 1 2019, Pages 237-269
Fourth universal definition of myocardial infarction (2018).
Thygesen K, Alpert JS, Jaffe AS, Chaitman BR, Bax JJ, Morrow DA, White HD, ESC Scientific Document Group
Abstract
Cited 20 times since 2019 (3 per year)
source: EuropePMC
Endocrine-related cancer,
Volume 26, Issue 1, 1 1 2019, Pages 1-12
Hotspot DAXX, PTCH2 and CYFIP2 mutations in pancreatic neuroendocrine neoplasms.
Vandamme T, Beyens M, Boons G, Schepers A, Kamp K, Biermann K, Pauwels P, De Herder WW, Hofland LJ, Peeters M, Van Camp G, Op de Beeck K
Mutations in DAXX/ATRX, MEN1 and genes involved in the phosphoinositide-3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway have been implicated in pancreatic neuroendocrine neoplasms (pNENs). However, mainly mutations present in the majority of tumor cells have been identified, while proliferation-driving mutations could be present only in small fractions of the tumor. This study aims to identify high- and low-abundance mutations in pNENs using ultra-deep targeted resequencing. F...
Abstract
Cited 113 times since 2019 (17 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 73, Issue 1, 1 1 2019, Pages 58-66
Association of the PHACTR1/EDN1 Genetic Locus With Spontaneous Coronary Artery Dissection.
Adlam D, Olson TM, Combaret N, Kovacic JC, Iismaa SE, Al-Hussaini A, O'Byrne MM, Bouajila S, Georges A, Mishra K, Braund PS, d'Escamard V, Huang S, Margaritis M, Nelson CP, de Andrade M, Kadian-Dodov D, Welch CA, Mazurkiewicz S, Jeunemaitre X, DISCO Consortium, Wong CMY, Giannoulatou E, Sweeting M, Muller D, Wood A, McGrath-Cadell L, Fatkin D, Dunwoodie SL, Harvey R, Holloway C, Empana JP, Jouven X, CARDIoGRAMPlusC4D Study Group, Olin JW, Gulati R, Tweet MS, Hayes SN, Samani NJ, Graham RM, Motreff P, Bouatia-Naji N
Background: Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndromes (ACS) afflicting predominantly younger to middle-aged women. Observational studies have reported a high prevalence of extracoronary vascular anomalies, especially fibromuscular dysplasia (FMD) and a low prevalence of coincidental cases of atherosclerosis. PHACTR1/EDN1 is a genetic risk locus for several vascular diseases, including FMD and coronary artery disease, with the pu...
Abstract
Cited 129 times since 2019 (19.4 per year)
source: EuropePMC
JACC. Cardiovascular interventions,
Volume 12, Issue 2, 1 1 2019, Pages 182-193
Predictors of Left Ventricular Outflow Tract Obstruction After Transcatheter Mitral Valve Replacement.
Yoon SH, Bleiziffer S, Latib A, Eschenbach L, Ancona M, Vincent F, Kim WK, Unbehaum A, Asami M, Dhoble A, Silaschi M, Frangieh AH, Veulemans V, Tang GHL, Kuwata S, Rampat R, Schmidt T, Patel AJ, Nicz PFG, Nombela-Franco L, Kini A, Kitamura M, Sharma R, Chakravarty T, Hildick-Smith D, Arnold M, de Brito FS, Jensen C, Jung C, Jilaihawi H, Smalling RW, Maisano F, Kasel AM, Treede H, Kempfert J, Pilgrim T, Kar S, Bapat V, Whisenant BK, Van Belle E, Delgado V, Modine T, Bax JJ, Makkar RR
Objectives: The aim of this study was to evaluate the predictors of left ventricular outflow tract (LVOT) obstruction after transcatheter mitral valve replacement (TMVR). Background: LVOT obstruction is a major concern with TMVR, but limited data exist regarding its predictors and impact on outcomes. Methods: Patients with pre-procedural multidetector row computed tomography (MDCT) undergoing TMVR for failed mitral bioprosthetic valves (valve-in-valve), annuloplasty rings (valve-in-ring), and mi...
Abstract
Cited 66 times since 2019 (9.9 per year)
source: EuropePMC
Circulation,
Volume 139, Issue 3, 1 1 2019, Pages 413-415
Outcomes Associated With Cardiogenic Shock in Takotsubo Syndrome.
Di Vece D, Citro R, Cammann VL, Kato K, Gili S, Szawan KA, Micek J, Jurisic S, Ding KJ, Bacchi B, Schwyzer M, Candreva A, Bossone E, D'Ascenzo F, Sarcon A, Franke J, Napp LC, Jaguszewski M, Noutsias M, Münzel T, Knorr M, Heiner S, Katus HA, Burgdorf C, Schunkert H, Thiele H, Bauersachs J, Tschöpe C, Pieske BM, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Hasenfuβ G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Empen K, Felix SB, Delmas C, Lairez O, El-Battrawy I, Akin I, Borggrefe M, Gilyarova E, Shilova A, Gilyarov M, Horowitz J, Kozel M, Tousek P, Widimský P, Winchester DE, Ukena C, Di Mario C, Prasad A, Böhm M, Bax JJ, Lüscher TF, Ruschitzka F, Ghadri JR, Templin C
Abstract
Circulation,
Volume 139, Issue 2, 1 1 2019, Pages 286-288
European Society of Cardiology Congress 2018.
Bax JJ, Achenbach S
Abstract
Cited 6 times since 2019 (0.9 per year)
source: EuropePMC
Travel medicine and infectious disease,
Volume 31, 1 1 2019, Pages 101362
Risk of acquisition of human diarrhoeagenic Escherichia coli virulence genes in intercontinental travellers: A prospective, multi-centre study.
van Hattem JM, Cabal A, Arcilla MS, Alvarez J, de Jong MD, Melles DC, Penders J, COMBAT consortium, Schmidt CG, Schultsz C
Background: We studied geographic distribution of diarrhoeagenic Escherichia coli virulence genes (DEC VGs) acquisition in travellers and investigated if they acquired highly virulent EAEC/STEC hybrid strains. Methods: From the prospective, multicentre COMBAT study among 2001 Dutch travellers, 491 travellers were selected based on travel destination to 7 subregions. Faecal samples taken directly before and after travel were screened for nine DEC VGs with real-time PCR. Incidence proportions and...
Abstract
Cited 11 times since 2019 (1.7 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 20, Issue 1, 1 1 2019, Pages 56-65
Left ventricular global longitudinal strain and long-term prognosis in patients with chronic obstructive pulmonary disease after acute myocardial infarction.
Goedemans L, Abou R, Hoogslag GE, Ajmone Marsan N, Delgado V, Bax JJ
Aims: Left ventricular (LV) systolic function is a known prognostic factor after ST-segment elevation myocardial infarction (STEMI). We evaluated the prognostic value of LV global longitudinal strain (GLS) in patients with chronic obstructive pulmonary disease (COPD) after STEMI. Methods and results: One hundred and forty-three STEMI patients with COPD (mean age 70 ± 11 years, 71% male), were retrospectively analysed. Left ventricular ejection fraction (LVEF) and LV GLS were measured on transtho...
Abstract
Cited 4 times since 2019 (0.6 per year)
source: EuropePMC
Annals of translational medicine,
Volume 7, Issue 1, 1 1 2019, Pages 9
Muscle weakness in a <i>S. pneumoniae</i> sepsis mouse model.
Witteveen E, Wieske L, Manders E, Verhamme C, Ottenheijm CAC, Schultz MJ, van Schaik IN, Horn J
Background: The pathophysiology of intensive care unit-acquired weakness (ICU-AW), which affects peripheral nerves, limb muscles and respiratory muscles, is complex and incompletely understood. This illustrates the need for an ICU-AW animal model. However, a translatable and easily applicable ICU-AW animal model does not exist. The objective of this study was to investigate whether induction of a S. pneumoniae sepsis could serve as a model for ICU-AW. Methods: A total of 24 C57BL/6J mice were in...
Abstract
Cited 17 times since 2019 (2.6 per year)
source: EuropePMC
Circulation,
Volume 139, Issue 1, 1 1 2019, Pages 134-136
High-Frequency Biomarker Measurements of Troponin, NT-proBNP, and C-Reactive Protein for Prediction of New Coronary Events After Acute Coronary Syndrome.
Oemrawsingh RM, Akkerhuis KM, de Mulder M, Umans VA, Kietselaer B, Schotborgh C, Ronner E, Lenderink T, Liem A, Haitsma D, van der Harst P, Asselbergs FW, Maas A, Oude Ophuis AJ, Ilmer B, Dijkgraaf R, de Winter RJ, Kie The SH, Wardeh AJ, Hermans W, Cramer E, van Schaik RH, Hoefer IE, Doevendans PA, Simoons ML, Boersma E, BIOMArCS Investigators
Abstract
Cited 36 times since 2019 (5.4 per year)
source: EuropePMC
Brain : a journal of neurology,
Volume 142, Issue 1, 1 1 2019, Pages 35-49
Integrated clinical and omics approach to rare diseases: novel genes and oligogenic inheritance in holoprosencephaly.
Kim A, Savary C, Dubourg C, Carré W, Mouden C, Hamdi-Rozé H, Guyodo H, Douce JL, FREX Consortium, GoNL Consortium, Pasquier L, Flori E, Gonzales M, Bénéteau C, Boute O, Attié-Bitach T, Roume J, Goujon L, Akloul L, Odent S, Watrin E, Watrin E, Dupé V, de Tayrac M, David V
Holoprosencephaly is a pathology of forebrain development characterized by high phenotypic heterogeneity. The disease presents with various clinical manifestations at the cerebral or facial levels. Several genes have been implicated in holoprosencephaly but its genetic basis remains unclear: different transmission patterns have been described including autosomal dominant, recessive and digenic inheritance. Conventional molecular testing approaches result in a very low diagnostic yield and most c...
Abstract
Cited 3 times since 2019 (0.5 per year)
source: EuropePMC
Tijdschrift voor psychiatrie,
Volume 61, Issue 10, 1 1 2019, Pages 683-691
[Guided web-based intervention for sleeping problems (I-Sleep) in depressed patients within outpatient specialist mental health care: a pilot study].
Dozeman E, van Straten A, van Genugten CR, van Schaik DJF
Background: Insomnia in depressed patients is usually targeted by medication, while cognitive behavioural treatment for insomnia (CBT-I) is the treatment of first choice. Effective online CBT-I is available but is not frequently offered in regular care. AIM: To determine the feasibility and indications for effectiveness of I-Sleep, an online CBT-I module, for uni- and bipolar depressed patients in specialised mental health care settings. METHOD: In a pilot study I-Sleep (5 sessions) was offered...
Abstract
Tijdschrift voor psychiatrie,
Volume 61, Issue 10, 1 1 2019, Pages 678-680
[Too early for pharmacogenetics in psychiatric practice? Implementation is in full swing].
van Westrhenen R, Bet PM, van Weelden M, van Schaik RHN
Abstract
Cited 10 times since 2019 (1.5 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 27, Issue 1, 1 1 2019, Pages 18-23
Expectations and perceived barriers to widespread implementation of e‑Health in cardiology practice: Results from a national survey in the Netherlands.
Treskes RW, Wildbergh TX, Schalij MJ, Scherptong RWC
Introduction: Expectations of physicians concerning e‑Health and perceived barriers to implementation in clinical practice are scarcely reported in the literature. The purpose of this study was to assess these aspects of cardiovascular e‑Health. Methods: A survey was sent to members of the Netherlands Society of Cardiology. In total, the questionnaire contained 30 questions about five topics: personal use of smartphones, digital communication between respondents and patients, current e‑Health im...
Abstract
