9618 results
Cited 2 times since 2017 (0.3 per year)
source: EuropePMC
Simulation in healthcare : journal of the Society for Simulation in Healthcare,
Volume 12, Issue 6, 1 1 2017, Pages 377-384
Increasing Authenticity of Simulation-Based Assessment in Diagnostic Radiology.
van der Gijp A, Ravesloot CJ, Tipker CA, de Crom K, Rutgers DR, van der Schaaf MF, van der Schaaf IC, Mol CP, Vincken KL, Ten Cate OTJ, Maas M, van Schaik JPJ
Introduction: Clinical reasoning in diagnostic imaging professions is a complex skill that requires processing of visual information and image manipulation skills. We developed a digital simulation-based test method to increase authenticity of image interpretation skill assessment. Methods: A digital application, allowing volumetric image viewing and manipulation, was used for three test administrations of the national Dutch Radiology Progress Test for residents. This study describes the develop...
Abstract
Cited 10 times since 2017 (1.3 per year)
source: EuropePMC
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group,
Volume 34, Issue 7, 1 1 2017, Pages 988-993
Intravesical radiofrequency induced hyperthermia enhances mitomycin C accumulation in tumour tissue.
van Valenberg FJP, van der Heijden AG, Lammers RJM, Falke J, Arends TJH, Oosterwijk E, Witjes JA
Introduction: Non-muscle invasive bladder cancer (NMIBC) is a highly recurrent disease with potential progression to muscle invasive disease despite the standard bladder instillations with mitomycin C (MMC) or Bacille Calmette-Guérin immunotherapy. Therefore, alternatives such as radiofrequency-induced chemohyperthermia (RF-CHT) with MMC are being investigated. The mechanism explaining the efficacy of RF-CHT is only partly understood. We examined whether RF-CHT results in higher MMC tissue conce...
Abstract
Cited 1 times since 2017 (0.1 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 25, Issue 12, 1 1 2017, Pages 655-663
Optimal duration of dual antiplatelet therapy after percutaneous coronary intervention or after acute coronary syndrome : Practical lessons from a review.
Ten Berg JM, Zwart B, van 't Hof AWJ, Liem A, Waltenberger J, de Winter RJ, Jukema JW
To prevent recurrent ischaemic events, dual antiplatelet therapy (DAPT) is the standard of care after percutaneous coronary intervention and in the treatment of acute coronary syndrome. Recent evidence supports an adjusted DAPT duration in selected patients.The current paper aims to encourage cardiologists to actively search for patients benefiting from either shorter or prolonged duration DAPT and proposes an algorithm to identify patients who are likely to benefit from such an alternative stra...
Abstract
Cited 6 times since 2017 (0.8 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 52, Issue 6, 1 1 2017, Pages 1161-1167
Right ventricular dysfunction after surgical left ventricular restoration: prevalence, risk factors and clinical implications.
Couperus LE, Delgado V, van Vessem ME, Tops LF, Palmen M, Braun J, Verwey HF, Klautz RJM, Schalij MJ, Beeres SLMA
Objectives: Surgical left ventricular (LV) restoration (SVR) induces changes in LV systolic and diastolic function that may affect postoperative right ventricular (RV) function. This study aimed to evaluate the long-term effect of SVR on RV function, with specific focus on determinants and prognostic implications of RV dysfunction. Methods: Eighty-six patients (age 60 ± 10 years, 73% male) with clinical and echocardiographic follow-up 2 years after SVR were included. RV dysfunction was defined a...
Abstract
Cited 30 times since 2017 (3.9 per year)
source: EuropePMC
The Journal of infectious diseases,
Volume 216, Issue 12, 1 1 2017, Pages 1513-1524
Whole-Genome Next-Generation Sequencing to Study Within-Host Evolution of Norovirus (NoV) Among Immunocompromised Patients With Chronic NoV Infection.
van Beek J, de Graaf M, Smits S, Schapendonk CME, Verjans GMGM, Vennema H, van der Eijk AA, Phan MVT, Cotten M, Koopmans M
Background: The genus Norovirus comprises large genetic diversity, and new GII.4 variants emerge every 2-3 years. It is unknown in which host these new variants originate. Here we study whether prolonged shedders within the immunocompromised population could be a reservoir for newly emerging strains. Methods: Sixty-five fecal samples from 16 immunocompromised patients were retrospectively selected. Isolated viral RNA was enriched by hybridization with a custom norovirus whole-genome RNA bait set...
Abstract
Cited 20 times since 2017 (2.6 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 70, Issue 23, 1 1 2017, Pages 2878-2889
Atrial Infarction and Ischemic Mitral Regurgitation Contribute to Post-MI Remodeling of the Left Atrium.
Aguero J, Galan-Arriola C, Fernandez-Jimenez R, Sanchez-Gonzalez J, Ajmone N, Delgado V, Solis J, Lopez GJ, de Molina-Iracheta A, Hajjar RJ, Bax JJ, Fuster V, Ibáñez B
Background: Left atrial (LA) remodeling after an acute myocardial infarction (MI) is poorly characterized regarding its determinants or its effect on ischemic mitral regurgitation (MR) development. Objectives: The purpose of this study was: 1) to compare LA structural remodeling in experimental MI swine models recapitulating the effects of left ventricular (LV) dysfunction, ischemic MR, and left atrial infarction (LAI); and 2) to analyze how LA remodeling influences ischemic MR development. Meth...
Abstract
Cited 153 times since 2017 (19.8 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 70, Issue 22, 1 1 2017, Pages 2752-2763
Transcatheter Aortic Valve Replacement in Pure Native Aortic Valve Regurgitation.
Yoon SH, Schmidt T, Bleiziffer S, Schofer N, Fiorina C, Munoz-Garcia AJ, Yzeiraj E, Amat-Santos IJ, Tchetche D, Jung C, Fujita B, Mangieri A, Deutsch MA, Ubben T, Deuschl F, Kuwata S, De Biase C, Williams T, Dhoble A, Kim WK, Ferrari E, Barbanti M, Vollema EM, Miceli A, Giannini C, Attizzani GF, Kong WKF, Gutierrez-Ibanes E, Jimenez Diaz VA, Wijeysundera HC, Kaneko H, Chakravarty T, Makar M, Sievert H, Hengstenberg C, Prendergast BD, Vincent F, Abdel-Wahab M, Nombela-Franco L, Silaschi M, Tarantini G, Butter C, Ensminger SM, Hildick-Smith D, Petronio AS, Yin WH, De Marco F, Testa L, Van Mieghem NM, Whisenant BK, Kuck KH, Colombo A, Kar S, Moris C, Delgado V, Maisano F, Nietlispach F, Mack MJ, Schofer J, Schaefer U, Bax JJ, Frerker C, Latib A, Makkar RR
Background: Limited data exist about safety and efficacy of transcatheter aortic valve replacement (TAVR) in patients with pure native aortic regurgitation (AR). Objectives: This study sought to compare the outcomes of TAVR with early- and new-generation devices in symptomatic patients with pure native AR. Methods: From the pure native AR TAVR multicenter registry, procedural and clinical outcomes were assessed according to VARC-2 criteria and compared between early- and new-generation devices....
Abstract
Cited 118 times since 2017 (15.3 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 70, Issue 25, 1 1 2017, Pages 3157-3172
Structure and Function of the Left Atrium and Left Atrial Appendage: AF and Stroke Implications.
Delgado V, Di Biase L, Leung M, Romero J, Tops LF, Casadei B, Marrouche N, Bax JJ
Atrial fibrillation (AF) and stroke are important major health problems that share common risk factors and frequently coexist. Left atrial (LA) remodeling is an important underlying substrate for AF and stroke. LA dilation and dysfunction form a prothrombotic milieu characterized by blood stasis and endothelial dysfunction. In addition, alterations of the atrial cardiomyocytes, increase of noncollagen deposits in the interstitial space and fibrosis, favor the occurrence of re-entry that predispo...
Abstract
Cited 7 times since 2017 (0.9 per year)
source: EuropePMC
PloS one,
Volume 12, Issue 11, 30 5 2017, Pages e0188048
Intracardiac anatomical relationships and potential for streaming in double inlet left ventricles.
Meyer SL, Jongbloed MR, Ho SY, Bartelings MM, McCarthy KP, Uemura H, Ebels T
The aim of this study was to gain better understanding of the variable anatomical features of double inlet left ventricle hearts without cavopulmonary connection that would potentially facilitate favorable streaming. Thirty-nine post-mortem specimens of double inlet left ventricle without cavopulmonary connection were investigated. The focus was on anatomical characteristics that could influence the flow and separation of deoxygenated and oxygenated blood in the ventricles. Elements of interest...
Abstract
Cited 51 times since 2017 (6.6 per year)
source: EuropePMC
Breast cancer research : BCR,
Volume 19, Issue 1, 28 4 2017, Pages 125
Serum concentrations of active tamoxifen metabolites predict long-term survival in adjuvantly treated breast cancer patients.
Helland T, Henne N, Bifulco E, Naume B, Borgen E, Kristensen VN, Kvaløy JT, Lash TL, Alnæs GIG, van Schaik RH, Janssen EAM, Hustad S, Lien EA, Mellgren G, Søiland H
Background: Controversies exist as to whether the genetic polymorphisms of the enzymes responsible for the metabolism of tamoxifen can predict breast cancer outcome in patients using adjuvant tamoxifen. Direct measurement of concentrations of active tamoxifen metabolites in serum may be a more biological plausible and robust approach. We have investigated the association between CYP2D6 genotypes, serum concentrations of active tamoxifen metabolites, and long-term outcome in tamoxifen treated bre...
Abstract
Cited 17 times since 2017 (2.2 per year)
source: EuropePMC
Pharmacotherapy,
Volume 37, Issue 12, 27 4 2017, Pages 1530-1536
Comparison of Weight-Based Dosing Strategies for Intravenous Immunoglobulin in Patients with Hematologic Malignancies.
Stump SE, Schepers AJ, Jones AR, Alexander MD, Auten JJ
Study objective: Intravenous immunoglobulin (IVIG) is a weight-based therapy used to treat and prevent infections in patients with hematologic malignancies. IVIG doses were calculated traditionally using actual body weight (ABW). However, limited pharmacokinetic data suggest dosing strategies using ideal body weight (IBW) or adjusted body weight (adjBW) may be appropriate given the small volume of distribution of IVIG. Our objective was to compare the effectiveness of using a precision-dosing st...
Abstract
Cited 145 times since 2017 (18.8 per year)
source: EuropePMC
Acta ophthalmologica,
Volume 96, Issue 1, 27 4 2017, Pages 63-68
Validation of automated screening for referable diabetic retinopathy with the IDx-DR device in the Hoorn Diabetes Care System.
van der Heijden AA, Abramoff MD, Verbraak F, van Hecke MV, Liem A, Nijpels G
Purpose: To increase the efficiency of retinal image grading, algorithms for automated grading have been developed, such as the IDx-DR 2.0 device. We aimed to determine the ability of this device, incorporated in clinical work flow, to detect retinopathy in persons with type 2 diabetes. Methods: Retinal images of persons treated by the Hoorn Diabetes Care System (DCS) were graded by the IDx-DR device and independently by three retinal specialists using the International Clinical Diabetic Retinop...
Abstract
Cited 7 times since 2017 (0.9 per year)
source: EuropePMC
BMC public health,
Volume 17, Issue 1, 25 4 2017, Pages 900
Social-cognitive determinants of the tick check: a cross-sectional study on self-protective behavior in combatting Lyme disease.
van der Heijden A, Mulder BC, Poortvliet PM, van Vliet AJH
Background: Performing a tick check after visiting nature is considered the most important preventive measure to avoid contracting Lyme disease. Checking the body for ticks after visiting nature is the only measure that can fully guarantee whether one has been bitten by a tick and provides the opportunity to remove the tick as soon as possible, thereby greatly reducing the chance of contracting Lyme disease. However, compliance to performing the tick check is low. In addition, most previous stud...
Abstract
Cited 7 times since 2017 (0.9 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 34, Issue 4, 24 4 2017, Pages 625-632
Disagreement between splenic switch-off and myocardial T1-mapping after caffeine intake.
Kuijpers D, van Dijk R, van Assen M, Kaandorp TAM, van Dijkman PRM, Vliegenthart R, van der Harst P, Oudkerk M
Caffeine is an adenosine receptor antagonist and a possible cause of inadequate stress perfusion. Splenic switch-off (SSO) and splenic rest-stress T1-mapping have been proposed as indicators of stress adequacy during perfusion cardiac magnetic resonance (CMR). We compared myocardial rest-stress T1-mapping with SSO and splenic rest-stress T1-mapping in patients with and without recent coffee intake. We analyzed 344 consecutive patients suspected of myocardial ischemia with adenosine perfusion CMR...
Abstract
Cited 33 times since 2017 (4.3 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 31, Issue 4, 23 4 2017, Pages 505-514.e3
Feasibility, Accuracy, and Reproducibility of Aortic Annular and Root Sizing for Transcatheter Aortic Valve Replacement Using Novel Automated Three-Dimensional Echocardiographic Software: Comparison with Multi-Detector Row Computed Tomography.
Prihadi EA, van Rosendael PJ, Vollema EM, Bax JJ, Delgado V, Ajmone Marsan N
Background: In transcatheter aortic valve replacement (TAVR), multi-detector row computed tomography (MDCT) is currently the standard imaging modality for correct prosthesis sizing, despite risks of radiation and contrast-induced renal injury. Three-dimensional (3D) transesophageal echocardiography (TEE) has been proposed as a potential alternative imaging technique, and recently, automated 3D transesophageal echocardiographic software (Aortic Valve Navigator [AVN], an unreleased prototype from...
Abstract
Cited 25 times since 2017 (3.2 per year)
source: EuropePMC
Trials,
Volume 18, Issue 1, 23 4 2017, Pages 558
The effects of using the PReDicT Test to guide the antidepressant treatment of depressed patients: study protocol for a randomised controlled trial.
Kingslake J, Dias R, Dawson GR, Simon J, Goodwin GM, Harmer CJ, Morriss R, Brown S, Guo B, Dourish CT, Ruhé HG, Lever AG, Veltman DJ, van Schaik A, Deckert J, Reif A, Stäblein M, Menke A, Gorwood P, Voegeli G, Pérez V, Browning M
Background: Antidepressant medication is commonly used to treat depression. However, many patients do not respond to the first medication prescribed and improvements in symptoms are generally only detectable by clinicians 4-6 weeks after the medication has been initiated. As a result, there is often a long delay between the decision to initiate an antidepressant medication and the identification of an effective treatment regimen. Previous work has demonstrated that antidepressant medications alt...
Abstract
Cited 57 times since 2017 (7.4 per year)
source: EuropePMC
European journal of preventive cardiology,
Volume 25, Issue 2, 22 4 2017, Pages 181-189
Age and gender differences in medical adherence after myocardial infarction: Women do not receive optimal treatment - The Netherlands claims database.
Eindhoven DC, Hilt AD, Zwaan TC, Schalij MJ, Borleffs CJW
Background Following myocardial infarction, medication is, besides lifestyle interventions, the cornerstone treatment to improve survival and minimize the occurrence of new cardiovascular events. Still, data on nationwide medication adherence are scarce. This study assesses medical adherence during one year following myocardial infarction, stratifying per type of infarct, age and gender. Design Retrospective cohort study. Methods In The Netherlands, all inhabitants are by law obliged to have hea...
Abstract
Cited 44 times since 2017 (5.7 per year)
source: EuropePMC
BMC genomics,
Volume 18, Issue 1, 21 3 2017, Pages 893
RNA-seq and Tn-seq reveal fitness determinants of vancomycin-resistant Enterococcus faecium during growth in human serum.
Zhang X, de Maat V, Guzmán Prieto AM, Prajsnar TK, Bayjanov JR, de Been M, Rogers MRC, Bonten MJM, Mesnage S, Willems RJL, van Schaik W
Background: The Gram-positive bacterium Enterococcus faecium is a commensal of the human gastrointestinal tract and a frequent cause of bloodstream infections in hospitalized patients. The mechanisms by which E. faecium can survive and grow in blood during an infection have not yet been characterized. Here, we identify genes that contribute to growth of E. faecium in human serum through transcriptome profiling (RNA-seq) and a high-throughput transposon mutant library sequencing approach (Tn-seq)...
Abstract
Cited 36 times since 2017 (4.7 per year)
source: EuropePMC
European journal of heart failure,
Volume 20, Issue 3, 21 3 2017, Pages 560-568
Prevalence of left ventricular systolic dysfunction in pre-dialysis and dialysis patients with preserved left ventricular ejection fraction.
Hensen LCR, Goossens K, Delgado V, Abou R, Rotmans JI, Jukema JW, Bax JJ
Aims: Patients with chronic kidney disease (CKD) have an excess of cardiovascular morbidity and mortality, with heart failure (HF) being particularly frequent. Reduced left ventricular ejection fraction (LVEF) defines left ventricular (LV) systolic dysfunction and is associated with poor prognosis. However, CKD patients may have HF symptoms with preserved LVEF. In this subgroup of patients, two-dimensional speckle tracking echocardiography can detect LV systolic dysfunction by analysing LV myoca...
Abstract
Cited 8 times since 2017 (1 per year)
source: EuropePMC
Diabetologia,
Volume 61, Issue 1, 20 3 2017, Pages 138-146
HbA<sub>1c</sub> is associated with altered expression in blood of cell cycle- and immune response-related genes.
Slieker RC, van der Heijden AAWA, van Leeuwen N, Mei H, Nijpels G, Beulens JWJ, 't Hart LM
Aims/hypothesis: Individuals with type 2 diabetes are heterogeneous in their glycaemic control as tracked by blood HbA1c levels. Here, we investigated the extent to which gene expression levels in blood reflect current and future HbA1c levels. Methods: HbA1c levels at baseline and 1 and 2 year follow-up were compared with gene expression levels in 391 individuals with type 2 diabetes from the Hoorn Diabetes Care System Cohort (15,564 genes, RNA sequencing). The functions of associated baseline g...
Abstract
