Research

Publications

Below you can find a list of our published research.

9618 results

Cited 12 times since 2017 (1.5 per year) source: EuropePMC

Heart rhythm, Volume 15, Issue 3, 20 3 2017, Pages 386-392 Implantable cardioverter-defibrillator therapy in hypertrophic cardiomyopathy: A SIMPLE substudy. Vamos M, Healey JS, Wang J, Connolly SJ, Mabo P, Van Erven L, Kautzner J, Glikson M, Neuzner J, O'Hara G, Vinolas X, Gadler F, Hohnloser SH

Background: Patients with hypertrophic cardiomyopathy (HCM) are considered to be at high risk for elevated defibrillation thresholds, periprocedural complications, and failed appropriate shocks. Objective: The purpose of this study was to determine the value of defibrillation testing (DT) in HCM patients undergoing implantable cardioverter-defibrillator (ICD) insertion. Methods: Defibrillation thresholds, perioperative complications, and long-term outcomes were compared between patients with HCM... Abstract

Cited 12 times since 2017 (1.5 per year) source: EuropePMC

Rheumatology international, Volume 38, Issue 3, 18 3 2017, Pages 443-453 Physical activity in patients with systemic sclerosis. Liem SIE, Meessen JMTA, Wolterbeek R, Ajmone Marsan N, Ninaber MK, Vliet Vlieland TPM, de Vries-Bouwstra JK

Objectives: To compare self-reported levels of physical activity (PA) of systemic sclerosis (SSc) patients with the general population. To evaluate in SSc patients factors associated with PA levels and needs and preferences regarding PA. Methods: Fifty nine SSc patients completed the Short QUestionnaire to ASsess Health-Enhancing PA. The proportion of patients meeting the Dutch Recommendation for PA (= moderate PA for 30 min on ≥ 5 days/week) and total minutes of PA per week were calculated and... Abstract

Cited 19 times since 2017 (2.5 per year) source: EuropePMC

Arteriosclerosis, thrombosis, and vascular biology, Volume 38, Issue 1, 16 3 2017, Pages 186-194 Statins Promote Cardiac Infarct Healing by Modulating Endothelial Barrier Function Revealed by Contrast-Enhanced Magnetic Resonance Imaging. Leenders GJ, Smeets MB, van den Boomen M, Berben M, Nabben M, van Strijp D, Strijkers GJ, Prompers JJ, Arslan F, Nicolay K, Vandoorne K

Objective: The endothelium has a crucial role in wound healing, acting as a barrier to control transit of leukocytes. Endothelial barrier function is impaired in atherosclerosis preceding myocardial infarction (MI). Besides lowering lipids, statins modulate endothelial function. Here, we noninvasively tested whether statins affect permeability at the inflammatory (day 3) and the reparative (day 7) phase of infarct healing post-MI using contrast-enhanced cardiac magnetic resonance imaging (MRI).... Abstract

Cited 25 times since 2017 (3.2 per year) source: EuropePMC

Scientific reports, Volume 7, Issue 1, 13 2 2017, Pages 15464 The effects of sociability on exploratory tendency and innovation repertoires in wild Sumatran and Bornean orangutans. Schuppli C, Forss S, Meulman E, Atmoko SU, van Noordwijk M, van Schaik C

It has been hypothesized that opportunities for social learning affect the size and complexity of the adult skill set of birds and mammals, their learning ability, and thus ultimately also their innovation frequency. To test these predictions we compared rates of social learning, rates of independent exploration (independent learning) and innovation repertoires between individuals of a highly sociable population of Pongo abelii at Suaq Balimbing and a less sociable population of Pongo pygmaeus w... Abstract

Cited 402 times since 2017 (51.8 per year) source: EuropePMC

Circulation, Volume 137, Issue 4, 13 2 2017, Pages 338-350 Low-Density Lipoprotein Cholesterol Lowering With Evolocumab and Outcomes in Patients With Peripheral Artery Disease: Insights From the FOURIER Trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk). Bonaca MP, Nault P, Giugliano RP, Keech AC, Pineda AL, Kanevsky E, Kuder J, Murphy SA, Jukema JW, Lewis BS, Tokgozoglu L, Somaratne R, Sever PS, Pedersen TR, Sabatine MS

Background: The PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitor evolocumab reduced low-density lipoprotein cholesterol and cardiovascular events in the FOURIER trial (Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk). We investigated the efficacy and safety of evolocumab in patients with peripheral artery disease (PAD) as well as the effect on major adverse limb events. Methods: FOURIER was a randomized trial of evolocumab versus place... Abstract

Cited 7 times since 2017 (0.9 per year) source: EuropePMC

BMJ open, Volume 7, Issue 11, 12 2 2017, Pages e018833 Barriers and facilitators to learn and improve through morbidity and mortality conferences: a qualitative study. de Vos MS, Hamming JF, Marang-van de Mheen PJ

Objectives: To explore barriers and facilitators to successful morbidity and mortality conferences (M&M), driving learning and improvement. Design: This is a qualitative study with semistructured interviews. Inductive, thematic content analysis was used to identify barriers and facilitators, which were structured across a pre-existing framework for change in healthcare. Setting: Dutch academic surgical department with a long tradition of M&M. Participants: An interview sample of surgeons... Abstract

Cited 174 times since 2017 (22.4 per year) source: EuropePMC

Scientific reports, Volume 7, Issue 1, 10 2 2017, Pages 15364 Global phylogenetic analysis of Escherichia coli and plasmids carrying the mcr-1 gene indicates bacterial diversity but plasmid restriction. Matamoros S, van Hattem JM, Arcilla MS, Willemse N, Melles DC, Penders J, Vinh TN, Thi Hoa N, Bootsma MCJ, van Genderen PJ, Goorhuis A, Grobusch M, Molhoek N, Oude Lashof AML, Stobberingh EE, Verbrugh HA, de Jong MD, Schultsz C

To understand the dynamics behind the worldwide spread of the mcr-1 gene, we determined the population structure of Escherichia coli and of mobile genetic elements (MGEs) carrying the mcr-1 gene. After a systematic review of the literature we included 65 E. coli whole genome sequences (WGS), adding 6 recently sequenced travel related isolates, and 312 MLST profiles. We included 219 MGEs described in 7 Enterobacteriaceae species isolated from human, animal and environmental samples. Despite a hig... Abstract

Cited 3 times since 2017 (0.4 per year) source: EuropePMC

BMC veterinary research, Volume 13, Issue 1, 9 2 2017, Pages 324 Quantitative and qualitative aspects of standing-up behavior and the prevalence of osteochondrosis in Warmblood foals on different farms: could there be a link? van Grevenhof EM, Gezelle Meerburg ARD, van Dierendonck MC, van den Belt AJM, van Schaik B, Meeus P, Back W

Background: Osteochondrosis (OC) is a common, clinically important joint disorder in which endochondral ossification is focally disturbed. Reduced blood supply to growing cartilage is considered an important cause of the condition, which has both genetic and environmental origins. Housing conditions can influence cartilage injury through peak-pressure changes during limb sliding. Additionally, circulatory perturbation can cause the avascular necrosis of cartilage. In this study, we evaluated the... Abstract

Cited 149 times since 2017 (19.1 per year) source: EuropePMC

The Lancet. Neurology, Volume 17, Issue 1, 6 1 2017, Pages 35-46 Subcutaneous immunoglobulin for maintenance treatment in chronic inflammatory demyelinating polyneuropathy (PATH): a randomised, double-blind, placebo-controlled, phase 3 trial. van Schaik IN, Bril V, van Geloven N, Hartung HP, Lewis RA, Sobue G, Lawo JP, Praus M, Mielke O, Durn BL, Cornblath DR, Merkies ISJ, PATH study group

Background: Approximately two-thirds of patients with chronic inflammatory demyelinating polyneuropathy (CIDP) need long-term intravenous immunoglobulin. Subcutaneous immunoglobulin (SCIg) is an alternative option for immunoglobulin delivery, but has not previously been investigated in a large trial of CIDP. The PATH study compared relapse rates in patients given SCIg versus placebo. Methods: Between March 12, 2012, and Sept 20, 2016, we studied patients from 69 neuromuscular centres in North Am... Abstract

Cited 9 times since 2017 (1.2 per year) source: EuropePMC

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 25, Issue 1, 6 1 2017, Pages 39-52 Myocardial perfusion imaging: Lessons learned and work to be done-update. Iskandrian AE, Dilsizian V, Garcia EV, Beanlands RS, Cerqueira M, Soman P, Berman DS, Cuocolo A, Einstein AJ, Morgan CJ, Hage FG, Schelbert HR, Bax JJ, Wu JC, Shaw LJ, Sadeghi MM, Tamaki N, Kaufmann PA, Gropler R, Dorbala S, Van Decker W

As the second term of our commitment to Journal begins, we, the editors, would like to reflect on a few topics that have relevance today. These include prognostication and paradigm shifts; Serial testing: How to handle data? Is the change in perfusion predictive of outcome and which one? Ischemia-guided therapy: fractional flow reserve vs perfusion vs myocardial blood flow; positron emission tomography (PET) imaging using Rubidium-82 vs N-13 ammonia vs F-18 Flurpiridaz; How to differentiate micr... Abstract

Cited 8 times since 2017 (1 per year) source: EuropePMC

JACC. Clinical electrophysiology, Volume 4, Issue 2, 6 1 2017, Pages 221-227 The Impact of Atrial Fibrillation Clinical Subtype on Mortality. Leung M, van Rosendael PJ, Abou R, Ajmone Marsan N, Leung DY, Delgado V, Bax JJ

Objectives: This study sought to investigate the prognostic implications of the clinical subtype of atrial fibrillation (AF): paroxysmal or persistent. Background: Underlying structural abnormalities of the left atrium may be responsible for the initial clinical presentation of AF in either paroxysmal or persistent form, yet the prognostic implications of the clinical subtype on presentation are unknown. Methods: Over a median of 7 years, 1,773 patients (age 64 ± 12 years, 74% males) with nonval... Abstract

Cited 77 times since 2017 (9.9 per year) source: EuropePMC

Current biology : CB, Volume 27, Issue 22, 2 1 2017, Pages 3487-3498.e10 Morphometric, Behavioral, and Genomic Evidence for a New Orangutan Species. Nater A, Mattle-Greminger MP, Nurcahyo A, Nowak MG, de Manuel M, Desai T, Groves C, Pybus M, Sonay TB, Roos C, Lameira AR, Wich SA, Askew J, Davila-Ross M, Fredriksson G, de Valles G, Casals F, Prado-Martinez J, Goossens B, Verschoor EJ, Warren KS, Singleton I, Marques DA, Pamungkas J, Perwitasari-Farajallah D, Rianti P, Tuuga A, Gut IG, Gut M, Orozco-terWengel P, van Schaik CP, Bertranpetit J, Anisimova M, Scally A, Marques-Bonet T, Meijaard E, Krützen M

Six extant species of non-human great apes are currently recognized: Sumatran and Bornean orangutans, eastern and western gorillas, and chimpanzees and bonobos [1]. However, large gaps remain in our knowledge of fine-scale variation in hominoid morphology, behavior, and genetics, and aspects of great ape taxonomy remain in flux. This is particularly true for orangutans (genus: Pongo), the only Asian great apes and phylogenetically our most distant relatives among extant hominids [1]. Designation... Abstract

Cited 4 times since 2017 (0.5 per year) source: EuropePMC

Journal of clinical lipidology, Volume 12, Issue 1, 2 1 2017, Pages 137-144.e1 Mendelian randomization analysis of cholesteryl ester transfer protein and subclinical atherosclerosis: A population-based study. Christen T, Trompet S, Noordam R, Blauw LL, Gast KB, Rensen PCN, Willems van Dijk K, Rosendaal FR, de Mutsert R, Jukema JW, NEO study

Background: Several trials to prevent cardiovascular disease by inhibiting cholesteryl ester transfer protein (CETP) have failed, except Randomized EValuation of the Effects of Anacetrapib through Lipid-modification. Thus far, it is unclear to what extent CETP is causally related to measures of atherosclerosis. Objective: The aim of the article was to study the causal relationship between genetically determined CETP concentration and carotid intima-media thickness (cIMT) in a population-based co... Abstract

Cited 3 times since 2017 (0.4 per year) source: EuropePMC

Lung cancer (Amsterdam, Netherlands), Volume 114, 2 1 2017, Pages 50-55 Esophageal ultrasound (EUS) assessment of T4 status in NSCLC patients. Kuijvenhoven JC, Crombag L, Breen DP, van den Berk I, Versteegh MIM, Braun J, Winkelman TA, van Boven W, Bonta PI, Rabe KF, Annema JT

Background: Mediastinal and central large vessels (T4) invasion by lung cancer is often difficult to assess preoperatively due to the limited accuracy of computed tomography (CT) scan of the chest. Esophageal ultrasound (EUS) can visualize the relationship of para-esophageally located lung tumors to surrounding mediastinal structures. Aim: To assess the value of EUS for detecting mediastinal invasion (T4) of centrally located lung tumors. Methods: Patients who underwent EUS for the diagnosis and... Abstract

Cited 55 times since 2017 (7.1 per year) source: EuropePMC

Annals of surgery, Volume 266, Issue 5, 1 1 2017, Pages 898-904 Textbook Outcome: A Composite Measure for Quality of Elective Aneurysm Surgery. Karthaus EG, Lijftogt N, Busweiler LAD, Elsman BHP, Wouters MWJM, Vahl AC, Hamming JF, Dutch Society of Vascular Surgery, the Steering Committee of the Dutch Surgical Aneurysm Audit, the Dutch Institute for Clinical Auditing

Objective: To investigate a new composite quality measurement, which comprises a desirable outcome for elective aneurysm surgery, called "Textbook Outcome" (TO). Background: Single-quality indicators in vascular surgery are often not distinctive and insufficiently reflect the quality of care. Methods: All patients undergoing elective abdominal aortic aneurysm repair, registered in the Dutch Surgical Aneurysm Audit between 2014 and 2015 were included. TO was defined as the percentage of... Abstract

Cited 22 times since 2017 (2.8 per year) source: EuropePMC

Current biology : CB, Volume 27, Issue 22, 1 1 2017, Pages 3576-3577 Morphometric, Behavioral, and Genomic Evidence for a New Orangutan Species. Nater A, Mattle-Greminger MP, Nurcahyo A, Nowak MG, de Manuel M, Desai T, Groves C, Pybus M, Sonay TB, Roos C, Lameira AR, Wich SA, Askew J, Davila-Ross M, Fredriksson G, de Valles G, Casals F, Prado-Martinez J, Goossens B, Verschoor EJ, Warren KS, Singleton I, Marques DA, Pamungkas J, Perwitasari-Farajallah D, Rianti P, Tuuga A, Gut IG, Gut M, Orozco-terWengel P, van Schaik CP, Bertranpetit J, Anisimova M, Scally A, Marques-Bonet T, Meijaard E, Krützen M

Abstract

Cited 1 times since 2017 (0.1 per year) source: EuropePMC

Clinical microbiology reviews, Volume 31, Issue 1, 1 1 2017, Pages e00082-17 Correction for Quainoo et al., "Whole-Genome Sequencing of Bacterial Pathogens: the Future of Nosocomial Outbreak Analysis". Quainoo S, Coolen JPM, van Hijum SAFT, Huynen MA, Melchers WJG, van Schaik W, Wertheim HFL

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Cited 12 times since 2017 (1.5 per year) source: EuropePMC

JCO precision oncology, Volume 1, 1 1 2017, Pages 1-10 Treatment Algorithm for Homozygous or Compound Heterozygous <i>DPYD</i> Variant Allele Carriers With Low-Dose Capecitabine. Henricks LM, Kienhuis E, de Man FM, van der Veldt AAM, Hamberg P, van Kuilenburg ABP, van Schaik RHN, Lunenburg CATC, Guchelaar HJ, Schellens JHM, Mathijssen RHJ

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Cited 1 times since 2017 (0.1 per year) source: EuropePMC

Medical education, Volume 51, Issue 11, 1 1 2017, Pages 1181-1182 Working with students with disabilities: simulation-based faculty development. Meeks L, Richards A, Chang A, van Schaik S

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Clinical genetics, Volume 92, Issue 5, 1 1 2017, Pages 565 Response to Ciuculete et al. Smit RAJ, le Cessie S, Jukema JW, Trompet S

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