7724 results
Cited 49 times since 2012 (3.9 per year)
source: EuropePMC
Gynecologic oncology,
Volume 127, Issue 1, 10 2 2012, Pages 126-130
Randomized comparison of near-infrared fluorescence lymphatic tracers for sentinel lymph node mapping of cervical cancer.
Schaafsma BE, van der Vorst JR, Gaarenstroom KN, Peters AA, Verbeek FP, de Kroon CD, Trimbos JB, van Poelgeest MI, Frangioni JV, van de Velde CJ, Vahrmeijer AL
Objective: Near-infrared fluorescence imaging using indocyanine green (ICG) has recently been introduced as a novel technique for sentinel lymph node (SLN) mapping in early-stage cervical cancer. Although preclinical research has shown that ICG adsorbed to human serum albumin (ICG:HSA) improves its performance, the need for HSA has not yet been confirmed in cervical cancer patients. The current randomized study aims to determine whether ICG:HSA offers advantages over using ICG alone. Methods: Ei...
Abstract
Cited 1 times since 2012 (0.1 per year)
source: EuropePMC
Clinical research in cardiology : official journal of the German Cardiac Society,
Volume 102, Issue 1, 6 1 2012, Pages 81-83
An uncommon complication of an aortic root aneurysm.
Montero Cabezas JM, de Riva Silva M, Martín Asenjo R, Hernández Hernández F
Abstract
Cited 59 times since 2012 (4.7 per year)
source: EuropePMC
PloS one,
Volume 7, Issue 7, 6 1 2012, Pages e40058
Integrating macrophages into organotypic co-cultures: a 3D in vitro model to study tumor-associated macrophages.
Linde N, Gutschalk CM, Hoffmann C, Yilmaz D, Mueller MM
Tumor progression is controlled by signals from cellular and extra-cellular microenvironment including stromal cells and the extracellular matrix. Consequently, three-dimensional in vitro tumor models are essential to study the interaction of tumor cells with their microenvironment appropriately in a biologically relevant manner. We have previously used organotypic co-cultures to analyze the malignant growth of human squamous cell carcinoma (SCC) cell lines on a stromal equivalent in vitro. In t...
Abstract
Cited 2 times since 2012 (0.2 per year)
source: EuropePMC
Brain & development,
Volume 35, Issue 4, 5 1 2012, Pages 356-359
Atypical phenotypes of DYT1 dystonia in three children.
Yilmaz U, Yüksel D, Atac FB, Yilmaz D, Verdi H, Senbil N
Unlabelled: DYT-1 dystonia is the most common primary dystonia seen in childhood. It is an autosomal dominantly inherited disorder caused by deletion of a GAG triplet in exon 5 of the DYT1 gene. It characteristically starts in a distal limb during late childhood, subsequently spreads to involve other body regions sparing oromandibular muscles. However, clinical presentation can vary remarkably with respect to age, site of onset and progression. In this study we present three early-onset DYT-1 dy...
Abstract
Cited 30 times since 2012 (2.4 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 32, Issue 9, 5 1 2012, Pages 2223-2231
Human ATP-binding cassette G1 controls macrophage lipoprotein lipase bioavailability and promotes foam cell formation.
Olivier M, Tanck MW, Out R, Villard EF, Lammers B, Bouchareychas L, Frisdal E, Superville A, Van Berkel T, Kastelein JJ, Eck MV, Jukema JW, Chapman MJ, Dallinga-Thie GM, Guerin M, Le Goff W
Objective: The physiological function of the ATP-binding cassette G1 (ABCG1) transporter in humans is not yet elucidated, as no genetic disease caused by ABCG1 mutations has been documented. The goal of our study was, therefore, to investigate the potential role(s) of ABCG1 in lipid metabolism in humans. Methods and results: Here we report that among the 104 polymorphisms present in the ABCG1 gene, the analysis of the frequent functional rs1893590 and rs1378577 single nucleotide polymorphisms lo...
Abstract
Cited 75 times since 2012 (5.9 per year)
source: EuropePMC
Annals of surgical oncology,
Volume 19, Issue 13, 3 1 2012, Pages 4104-4111
Randomized comparison of near-infrared fluorescence imaging using indocyanine green and 99(m) technetium with or without patent blue for the sentinel lymph node procedure in breast cancer patients.
van der Vorst JR, Schaafsma BE, Verbeek FP, Hutteman M, Mieog JS, Lowik CW, Liefers GJ, Frangioni JV, van de Velde CJ, Vahrmeijer AL
Background: Near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) has the potential to improve sentinel lymph node (SLN) mapping of breast cancer. We performed a randomized clinical trial to assess the value of blue dyes when used in combination with NIR fluorescence. We also preliminarily examined the possibility of performing SLN mapping without radiotracers. Methods: Clinical trial subjects were 24 consecutive breast cancer patients scheduled to undergo SLN biopsy. All patien...
Abstract
Cited 2 times since 2012 (0.2 per year)
source: EuropePMC
International journal of computer assisted radiology and surgery,
Volume 7, Issue 5, 3 1 2012, Pages 753-767
Cardiac MRI visualization for ventricular tachycardia ablation.
Godeschalk-Slagboom CJ, van der Geest RJ, Zeppenfeld K, Botha CP
Objective: The integrated visualization of cardiac MRI during a ventricular tachycardia (VT) mapping and ablation procedure would provide improved catheter guidance and tissue assessment. We developed a system for and explored the added value of simultaneous visualization of intracardiac voltage measurements and MRI-derived myocardial scar information during VT ablation procedures. Method: We propose the use of a synchronized 3D and 2D view. In 3D, the catheter will be guided optimally by assess...
Abstract
Cited 11 times since 2012 (0.9 per year)
source: EuropePMC
Interactive cardiovascular and thoracic surgery,
Volume 15, Issue 4, 3 1 2012, Pages 685-689
Serum cortisol concentration with exploratory cut-off values do not predict the effects of hydrocortisone administration in children with low cardiac output after cardiac surgery.
Verweij EJ, Hogenbirk K, Roest AA, van Brempt R, Hazekamp MG, de Jonge E
Objectives: Low cardiac output syndrome is common after paediatric cardiac surgery. Previous studies suggested that hydrocortisone administration may improve haemodynamic stability in case of resistant low cardiac output syndrome in critically ill children. This study was set up to test the hypothesis that the effects of hydrocortisone on haemodynamics in children with low cardiac output syndrome depend on the presence of (relative) adrenal insufficiency. Methods: A retrospective study was done...
Abstract
Cited 37 times since 2012 (2.9 per year)
source: EuropePMC
World journal of gastrointestinal surgery,
Volume 4, Issue 7, 1 1 2012, Pages 180-184
Near-infrared fluorescence imaging of a solitary fibrous tumor of the pancreas using methylene blue.
van der Vorst JR, Vahrmeijer AL, Hutteman M, Bosse T, Smit VT, van de Velde CJ, Frangioni JV, Bonsing BA
A 67-year-old female presented with unexplained abdominal pain. A contrast-enhanced computed tomography scan of the abdomen incidentally revealed a mass in the uncinate process of the pancreas. This mass was resected and based on histopathological findings, diagnosed as a solitary fibrous tumor (SFT) of the pancreas. A SFT is an extremely rare benign mesenchymal tumor that in 65% of cases affects the visceral pleura but can also affect extra-pleural sites. The intraoperative demarcation of pancr...
Abstract
Cited 26 times since 2012 (2.1 per year)
source: EuropePMC
Journal of cellular and molecular medicine,
Volume 16, Issue 7, 1 1 2012, Pages 1508-1521
Cardiomyogenic differentiation-independent improvement of cardiac function by human cardiomyocyte progenitor cell injection in ischaemic mouse hearts.
den Haan MC, Grauss RW, Smits AM, Winter EM, van Tuyn J, Pijnappels DA, Steendijk P, Gittenberger-De Groot AC, van der Laarse A, Fibbe WE, de Vries AA, Schalij MJ, Doevendans PA, Goumans MJ, Atsma DE
We previously showed that human cardiomyocyte progenitor cells (hCMPCs) injected after myocardial infarction (MI) had differentiated into cardiomyocytes in vivo 3 months after MI. Here, we investigated the short-term (2 weeks) effects of hCMPCs on the infarcted mouse myocardium. MI was induced in immunocompromised (NOD/scid) mice, immediately followed by intramyocardial injection of hCMPCs labelled with enhanced green fluorescent protein (hCMPC group) or vehicle only (control group). Sham-operat...
Abstract
Cited 2 times since 2012 (0.2 per year)
source: EuropePMC
Journal of fish biology,
Volume 81, Issue 2, 1 1 2012, Pages 750-765
Spawning migrations of the endemic Labeobarbus (Cyprinidae, Teleostei) species of Lake Tana, Ethiopia: status and threats.
Anteneh W, Getahun A, Dejen E, Sibbing FA, Nagelkerke LA, De Graaf M, Wudneh T, Vijverberg J, Palstra AP
The reproductive biology of the only known intact species flock of large cyprinids, the 16 Labeobarbus species of Lake Tana (Ethiopia), has been extensively studied for the past two decades. Seven species of Labeobarbus are known to migrate >50 km upstream into tributary rivers for spawning during the rainy season (July to October), whereas eight other species are absent from these rivers and probably developed a new strategy of lacustrine spawning (macro-spatial segregation). One species (L....
Abstract
Postgraduate medical journal,
Volume 88, Issue 1041, 1 1 2012, Pages 418-424
Republished: How to reduce sudden cardiac death in patients with renal failure.
de Bie MK, Buiten MS, Rabelink TJ, Jukema JW
Abstract
Cited 17 times since 2012 (1.3 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 5, Issue 4, 1 1 2012, Pages 525-535
Emerging role of multimodality imaging to evaluate patients at risk for sudden cardiac death.
Bertini M, Schalij MJ, Bax JJ, Delgado V
Abstract
Cited 21 times since 2012 (1.7 per year)
source: EuropePMC
Clinical research in cardiology : official journal of the German Cardiac Society,
Volume 101, Issue 7, 1 1 2012, Pages 509-519
Psychosocial impact of implantable cardioverter defibrillators (ICD) in young adults with Tetralogy of Fallot.
Opić P, Utens EM, Moons P, Theuns DA, van Dijk AP, Hoendermis ES, Vliegen HW, de Groot NM, Witsenburg M, Schalij M, Roos-Hesselink JW
Objective: To investigate the psychosocial impact of having an implantable cardioverter defibrillator (ICD) in adults with Tetralogy of Fallot (ToF). Methods: Included were 26 ToF-patients with an ICD (age 44 ± 12 years), and two control groups consisting of 28 ToF-patients without an ICD (age 40 ± 10 years) and a group of 35 ICD-patients of older age without ToF (age 72.0 ± 8 years). This last control group was chosen to represent the "older general ICD population" with acquired heart...
Abstract
Cited 25 times since 2012 (2 per year)
source: EuropePMC
Clinical endocrinology,
Volume 77, Issue 1, 1 1 2012, Pages 99-105
Changes in heart valve structure and function in patients treated with dopamine agonists for prolactinomas, a 2-year follow-up study.
Delgado V, Biermasz NR, van Thiel SW, Ewe SH, Marsan NA, Holman ER, Feelders RA, Smit JW, Bax JJ, Pereira AM
Objective: The use of ergot-derived dopamine agonists (DA) to treat patients with prolactinomas has not been associated with an increased risk of significant heart valve dysfunction. Accordingly, the present study evaluated whether the long-term use of DA for hyperprolactinaemia may be associated with increased risk of significant valvular heart disease. Methods: A total of 74 patients (mean age 48 ± 1·4 years, 23% male) with prolactinoma treated with DA for at least 1 year were evaluated with 2...
Abstract
Cited 46 times since 2012 (3.6 per year)
source: EuropePMC
European journal of heart failure,
Volume 14, Issue 9, 22 4 2012, Pages 1067-1074
Sildenafil enhances systolic adaptation, but does not prevent diastolic dysfunction, in the pressure-loaded right ventricle.
Borgdorff MA, Bartelds B, Dickinson MG, Boersma B, Weij M, Zandvoort A, Silljé HH, Steendijk P, de Vroomen M, Berger RM
Aim: Right ventricular (RV) failure due to pressure or volume overload is a major risk factor for early mortality in congenital heart disease and pulmonary hypertension, but currently treatments are lacking. We aimed to demonstrate that the phosphodiesterase 5A inhibitor sildenafil can prevent adverse remodelling and improve function in chronic abnormal RV overload, independent from effects on the pulmonary vasculature. Methods and results: In rat models of either pressure or volume overload, we...
Abstract
Cited 9 times since 2012 (0.7 per year)
source: EuropePMC
Journal of magnetic resonance imaging : JMRI,
Volume 36, Issue 6, 22 4 2012, Pages 1470-1476
Evaluation of sampling density on the accuracy of aortic pulse wave velocity from velocity-encoded MRI in patients with Marfan syndrome.
Kröner ES, van der Geest RJ, Scholte AJ, Kroft LJ, van den Boogaard PJ, Hendriksen D, Lamb HJ, Siebelink HM, Mulder BJ, Groenink M, Radonic T, Hilhorst-Hofstee Y, Bax JJ, van der Wall EE, de Roos A, Reiber JH, Westenberg JJ
Purpose: To evaluate the effect of spatial (ie, number of sampling locations along the aorta) and temporal sampling density on aortic pulse wave velocity (PWV) assessment from velocity-encoded MRI in patients with Marfan syndrome (MFS). Materials and methods: Twenty-three MFS patients (12 men, mean age 36 ± 14 years) were included. Three PWV-methods were evaluated: 1) reference PWV(i.p.) from in-plane velocity-encoded MRI with dense temporal and spatial sampling; 2) conventional PWV(t.p.) from t...
Abstract
Cited 8 times since 2012 (0.6 per year)
source: EuropePMC
Revista espanola de cardiologia (English ed.),
Volume 65, Issue 11, 22 4 2012, Pages 1062-1064
1:1 atrial flutter after vernakalant administration for atrial fibrillation cardioversion.
de Riva-Silva M, Montero-Cabezas JM, Salgado-Aranda R, López-Gil M, Fontenla-Cerezuela A, Arribas-Ynsaurriaga F
Abstract
Cited 72 times since 2012 (5.7 per year)
source: EuropePMC
Geriatrics & gerontology international,
Volume 13, Issue 2, 21 3 2012, Pages 334-341
More than half of hip fracture patients do not regain mobility in the first postoperative year.
Vochteloo AJ, Moerman S, Tuinebreijer WE, Maier AB, de Vries MR, Bloem RM, Nelissen RG, Pilot P
Aim: To measure functional recovery and determine risk factors for failure to return to the prefracture level of mobility of hip fracture patients 1 year postoperatively. Methods: A prospective cohort follow-up study of 390 hip fracture patients aged 65 years and older was carried out. Patients were stratified in categories based on prefracture mobility: mobile without aid, with aid in- and outdoors, or only mobile indoors. Immobile patients were excluded. Risk factors for not regaining prefract...
Abstract
Cited 50 times since 2012 (3.9 per year)
source: EuropePMC
The Journal of general virology,
Volume 93, Issue Pt 9, 20 3 2012, Pages 1996-2007
Genetic evolution of the neuraminidase of influenza A (H3N2) viruses from 1968 to 2009 and its correspondence to haemagglutinin evolution.
Westgeest KB, de Graaf M, Fourment M, Bestebroer TM, van Beek R, Spronken MIJ, de Jong JC, Rimmelzwaan GF, Russell CA, Osterhaus ADME, Smith GJD, Smith DJ, Fouchier RAM
Each year, influenza viruses cause epidemics by evading pre-existing humoral immunity through mutations in the major glycoproteins: the haemagglutinin (HA) and the neuraminidase (NA). In 2004, the antigenic evolution of HA of human influenza A (H3N2) viruses was mapped (Smith et al., Science 305, 371-376, 2004) from its introduction in humans in 1968 until 2003. The current study focused on the genetic evolution of NA and compared it with HA using the dataset of Smith and colleagues, updated to...
Abstract
