Research

Publications

Below you can find a list of our published research.

9618 results

Cited 22 times since 1997 (0.8 per year) source: EuropePMC

Pediatric radiology, Volume 27, Issue 11, 1 1 1997, Pages 855-857 Transvenous embolisation of an arteriovenous malformation of the mandible via a femoral approach. Beek FJ, ten Broek FW, van Schaik JP, Mali WP

Arteriovenous malformations (AVM) of the mandible are uncommon but can give rise to sudden massive haemorrhage. Transarterial or direct transosseous embolisation can be used to treat this condition but is not always effective. We describe a case of mandibular AVM with a single draining vein which was embolised successfully via a femoral transvenous approach. Abstract

Cited 38 times since 1997 (1.4 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 30, Issue 6, 1 1 1997, Pages 1491-1499 Modulation of lipoprotein(a) atherogenicity by high density lipoprotein cholesterol levels in middle-aged men with symptomatic coronary artery disease and normal to moderately elevated serum cholesterol. Regression Growth Evaluation Statin Study (REGRESS) Study Group. Cobbaert C, Jukema JW, Zwinderman AH, Withagen AJ, Lindemans J, Bruschke AV

Objectives: This study sought to examine whether lipoprotein(a) levels predict coronary artery lumen changes in patients with symptomatic coronary artery disease (CAD) and normal to moderate hypercholesterolemia. Background: Recent conflicting reports have confirmed or refuted the association of lipoprotein(a) with clinical events or angiographically verified disease progression. Methods: The association between serum lipoprotein(a) and changes in coronary artery lumen was studied in 704 men ent... Abstract

Cited 93 times since 1997 (3.3 per year) source: EuropePMC

Arteriosclerosis, thrombosis, and vascular biology, Volume 17, Issue 11, 1 1 1997, Pages 2837-2842 Common C-to-T substitution at position -480 of the hepatic lipase promoter associated with a lowered lipase activity in coronary artery disease patients. Jansen H, Verhoeven AJ, Weeks L, Kastelein JJ, Halley DJ, van den Ouweland A, Jukema JW, Seidell JC, Birkenhäger JC

We studied the molecular basis of low hepatic lipase (HL) activity in normolipidemic male patients with angiographically documented coronary artery disease (CAD). In 18 subjects with a lowered HL activity (< 225 mU/mL), all nine exons of the HL gene and part of the promoter region (nucleotides -524 to +7) were sequenced. No structural mutations in the coding part of the HL gene were found, but 50% of the subjects showed a C-to-T substitution at nucleotide -480. Screening for the base substitu... Abstract

Cited 13 times since 1997 (0.5 per year) source: EuropePMC

The Journal of thoracic and cardiovascular surgery, Volume 114, Issue 5, 1 1 1997, Pages 844-846 Switch back: using the pulmonary autograft to replace the aortic valve after arterial switch operation. Hazekamp MG, Schoof PH, Suys BE, Hutter PA, Meijboom EJ, Ottenkamp J, Huysmans HA

Abstract

Cited 19 times since 1997 (0.7 per year) source: EuropePMC

Arteriosclerosis, thrombosis, and vascular biology, Volume 17, Issue 10, 1 1 1997, Pages 2177-2187 Involvement of calcium and G proteins in the acute release of tissue-type plasminogen activator and von Willebrand factor from cultured human endothelial cells. van den Eijnden-Schrauwen Y, Atsma DE, Lupu F, de Vries RE, Kooistra T, Emeis JJ

In this study, we investigated the role of Ca2+ and G proteins in thrombin-induced acute release (regulated secretion) of tissue-type plasminogen activator (TPA) and von Willebrand factor (vWF), using a previously described system of primary human umbilical vein endothelial cells (HUVECs). The acute release of TPA and vWF, as induced by alpha-thrombin, was almost zero after chelation of Ca2+i, showing that an increase in [Ca2+]i was required. It did not matter whether the increase in [Ca2+]i cam... Abstract

Cited 13 times since 1997 (0.5 per year) source: EuropePMC

Journal of neurology, neurosurgery, and psychiatry, Volume 63, Issue 4, 1 1 1997, Pages 534-536 Machado-Joseph disease presenting as severe asymmetric proximal neuropathy. van Schaik IN, Jöbsis GJ, Vermeulen M, Keizers H, Bolhuis PA, de Visser M

Despite much effort, a 74 year old man with progressive proximal weakness and sensory disturbances due to axonal neuropathy remained a diagnostic problem. Investigation of his family disclosed an additional patient with a cerebellar syndrome and a family member with mainly pyramidal features. Analysis of DNA showed a CAG repeat expansion in the Machado-Joseph disease gene in all three patients. Although not conclusively proved, we think that the neuropathy of the index case is linked to the CAG... Abstract

Cited 4 times since 1997 (0.1 per year) source: EuropePMC

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, Volume 235, Issue 10, 1 1 1997, Pages 639-646 Permeability of the blood-retinal barrier in healthy humans. European Concerted Action on Ocular Fluorometry. Van Schaik HJ, Heintz B, Larsen M, Leite E, Rosas V, Schalnus R, Van Best JA

Background: The aim of this study was to compare the inward permeability of the blood-retinal barrier in healthy subjects from six European cities. Methods: Seventy-two healthy subjects (age 20-70 years) were selected. At 30 min and 60 min after fluorescein injection, fluorescein mass in vitreous was calculated from the concentrations measured along the optical axis of the eye. Non-protein-bound fluorescein (NPBF) concentrations were measured in plasma prepared from blood samples taken 7, 15 and... Abstract

Cited 110 times since 1997 (3.9 per year) source: EuropePMC

Circulation, Volume 96, Issue 8, 1 1 1997, Pages 2573-2577 Thermolabile methylenetetrahydrofolate reductase in coronary artery disease. Kluijtmans LA, Kastelein JJ, Lindemans J, Boers GH, Heil SG, Bruschke AV, Jukema JW, van den Heuvel LP, Trijbels FJ, Boerma GJ, Verheugt FW, Willems F, Blom HJ

Background: Hyperhomocysteinemia, an independent and graded risk factor for coronary artery disease (CAD), may result from both environmental and hereditary factors. Methylenetetrahydrofolate reductase (MTHFR) catalyzes the conversion of methylenetetrahydrofolate to methyltetrahydrofolate, the methyl donor in the remethylation of homocysteine to methionine. A 677C-->T mutation in the MTHFR gene has been associated with elevated homocysteine concentrations in homozygous (+/+) individuals. Meth... Abstract

Cited 8 times since 1997 (0.3 per year) source: EuropePMC

The Journal of thoracic and cardiovascular surgery, Volume 114, Issue 4, 1 1 1997, Pages 560-567 Acute elevation of coronary venous pressure does not affect left ventricular contractility in the normal and stressed swine heart: implications for the Fontan operation. Klautz RJ, van Rijk-Zwikker GL, Steendijk P, Wilde J, Teitel DF, Baan J

Objective: After the Fontan operation the right atrium and, thus, the coronary sinus are connected to the pulmonary arterial system, which causes the coronary venous pressure to increase. We investigated the acute effects of elevation of coronary venous pressure on baseline hemodynamics, coronary venous flow, and left ventricular contractility. Methods: In acutely instrumented pigs, during complete right heart bypass and during constant cardiac output, pressure in the right atrium, right ventric... Abstract

Cited 11 times since 1997 (0.4 per year) source: EuropePMC

AJR. American journal of roentgenology, Volume 169, Issue 4, 1 1 1997, Pages 995-999 Biventricular function in patients with nonischemic right ventricle tachyarrhythmias assessed with MR imaging. Kayser HW, Schalij MJ, van der Wall EE, Stoel BC, de Roos A

Abstract

Cited 2 times since 1997 (0.1 per year) source: EuropePMC

The Journal of pathology, Volume 183, Issue 1, 1 1 1997, Pages 99-104 Identification of host and donor cells in porcine homograft heart valve explants by fluorescence in situ hybridization. Braun J, Hazekamp MG, Koolbergen DR, Sugihara H, Goffin YA, Huysmans HA, Cornelisse CJ

The pathogenesis of the primary tissue degeneration that limits the life-span of aortic and pulmonary homografts has still not been revealed. Histopathological studies on homograft explants have not given definitive insight into the eventual fate of donor cells, nor have they demonstrated the assumed importance of host cell ingrowth into the graft tissue. In this experimental study, fluorescence in situ hybridization (FISH) is introduced as a new approach to examine the distribution of host and... Abstract

Investigative radiology, Volume 32, Issue 9, 1 1 1997, Pages 540-549 Quantitative assessment of the presence of a single leg separation in Björk-Shiley convexoconcave prosthetic heart valves. Vrooman HA, Maliepaard C, van der Linden LP, Jessurun ER, Ludwig JW, Plokker HW, Schalij MJ, Weeda HW, Laufer JL, Huysmans HA, Reiber JH

Rationale and objectives: The authors developed an analytic software package for the objective and reproducible assessment of a single leg separation (SLS) in the outlet strut of Björk-Shiley convexoconcave (BSCC) prosthetic heart valves. Methods: The radiographic cinefilm recordings of 18 phantom valves (12 intact and 6 SLS) and of 43 patient valves were acquired. After digitization of regions of interest in a cineframe, several processing steps were carried out to obtain a one-dimensional corr... Abstract

Cited 31 times since 1997 (1.1 per year) source: EuropePMC

European heart journal, Volume 18, Issue 9, 1 1 1997, Pages 1505-1513 Comparison of echocardiography with magnetic resonance imaging in the assessment of the athlete's heart. Pluim BM, Beyerbacht HP, Chin JC, Zwinderman A, Van der Laarse A, De Roos A, Vliegen HW, Van der Wall EE

Aim: The purpose of the study was to compare the accuracy of M-mode echocardiography and two different two-dimensional echocardiographic approaches in the assessment of left ventricular mass and volumes in endurance-trained and strength-trained athletes, using magnetic resonance imaging as reference standard. Methods and results: We studied 19 athletes and 10 untrained control subjects, M-mode and two-dimensional echocardiography were compared to magnetic resonance imaging. M-mode echocardiograp... Abstract

Cited 5 times since 1997 (0.2 per year) source: EuropePMC

Memory & cognition, Volume 25, Issue 5, 1 1 1997, Pages 641-652 Location errors in partial-report bar-probe experiments: in search of the origin of cue-alignment problems. Hagenaar R, van der Heijden AH

In studies using Averbach and Coriell's (1961) partial-report bar-probe paradigm with linear arrays, most errors involve the naming of an item that was in the display but in a position other than the cued one. Up to now, there is no general agreement on the origin of these location errors. Point of departure in this paper is that part of the location errors arises from inappropriate application of the cue. It is tested whether this originates from problems to perceive the position of the cu... Abstract

Cited 6 times since 1997 (0.2 per year) source: EuropePMC

Circulation, Volume 96, Issue 3, 1 1 1997, Pages 1025-1030 Hemodynamic effects of chronic prenatal ventricular pacing for the treatment of complete atrioventricular block. Liddicoat JR, Klein JR, Reddy VM, Klautz RJ, Teitel DF, Hanley FL

Background: Increasing the heart rate of the fetus with cardiac failure caused by complete AV block (CAVB) may allow delivery of a full-term, stable neonate with preserved ventricular function. Direct fetal pacing may be a feasible method to achieve this, but the effect of pacing on the structure and function of the rapidly developing fetal heart is unknown. Methods and results: CAVB was created in fetal lambs at 80% gestation by cryoablating the AV node. Epicardial ventricular pacing at 130 bpm... Abstract

Cited 37 times since 1997 (1.3 per year) source: EuropePMC

The Annals of thoracic surgery, Volume 64, Issue 2, 1 1 1997, Pages 521-525 Modified ultrafiltration after cardiopulmonary bypass in pediatric cardiac surgery. Draaisma AM, Hazekamp MG, Frank M, Anes N, Schoof PH, Huysmans HA

Background: Cardiopulmonary bypass in children results in considerable water retention, especially in neonates and small infants. Dilution of plasma proteins increases water loss into the extravascular compartments. Excessive total body water may prolong ventilatory support and may contribute to a prolongation of intensive care convalescence. After discontinuation of cardiopulmonary bypass, modified ultrafiltration can be used to withdraw plasma water from the total circulating volume. Methods:... Abstract

Cited 26 times since 1997 (0.9 per year) source: EuropePMC

Pediatric research, Volume 42, Issue 2, 1 1 1997, Pages 169-173 Surfactant dysfunction develops in BALB/c mice infected with respiratory syncytial virus. Van Schaik SM, Vargas I, Welliver RC, Enhorning G

Recent reports suggest an important role for pulmonary surfactant in maintaining the patency of narrow conducting airways. The hypothesis that surfactant dysfunction is an important factor in respiratory syncytial virus (RSV) infection was tested in a mouse model. Mice, inoculated with either a low or a high dose of RSV, were subjected to bronchoalveolar lavage (BAL), and the fluids were analyzed for percentage of inflammatory cells and concentrations of proteins and phospholipids. After concent... Abstract

Cited 28 times since 1997 (1 per year) source: EuropePMC

The Prostate, Volume 32, Issue 3, 1 1 1997, Pages 196-204 Plasminogen activator and matrix metalloproteinase production and extracellular matrix degradation by rat prostate cancer cells in vitro: correlation with metastatic behavior in vivo. Quax PH, de Bart AC, Schalken JA, Verheijen JH

Background: The plasminogen activation (PA) and metalloproteinase (MMP) system are involved in tumor cell migration and invasion. Methods: The proteolytic activity of cell lines originating from the rat Dunning R-3327 prostate tumor was analyzed by measuring in vitro extracellular matrix degradation, enzyme activity, and mRNA levels of enzymes, inhibitors, and receptors, and compared with their known metastatic behavior in vivo. Results: Only the highly metastatic sublines AT-3, MATLu, and MATLy... Abstract

Cited 33 times since 1997 (1.2 per year) source: EuropePMC

Thrombosis and haemostasis, Volume 78, Issue 2, 1 1 1997, Pages 880-886 The migration of human smooth muscle cells in vitro is mediated by plasminogen activation and can be inhibited by alpha2-macroglobulin receptor associated protein. Wijnberg MJ, Quax PH, Nieuwenbroek NM, Verheijen JH

The plasminogen activation system is thought to be important in cell migration processes. A role for this system during smooth muscle cell migration after vascular injury has been suggested from several animal studies. However, not much is known about its involvement in human vascular remodelling. We studied the involvement of the plasminogen activation system in human smooth muscle cell migration in more detail using an in vitro wound assay and a matrix invasion assay. Inhibition of plasmin act... Abstract

Cited 174 times since 1997 (6.2 per year) source: EuropePMC

Journal of dairy science, Volume 80, Issue 8, 1 1 1997, Pages 1833-1840 Estimation of variance components for somatic cell counts to determine thresholds for uninfected quarters. Schepers AJ, Lam TJ, Schukken YH, Wilmink JB, Hanekamp WJ

The objective of this study was to determine the factors affecting somatic cell count (SCC), to estimate variance components of these factors, and to calculate and evaluate the thresholds for intramammary infection based on SCC. The infection status from 22,467 quarter milk samples from 544 cows in seven herds was determined. Infections status was the most important factor affecting SCC. The increase in SCC was more pronounced for major pathogens than for minor pathogens. Even after adjustment f... Abstract