Research

Publications

Below you can find a list of our published research.

9618 results

Cited 30 times since 2009 (1.8 per year) source: EuropePMC

IEEE transactions on medical imaging, Volume 28, Issue 4, 10 2 2009, Pages 595-607 Automated detection of regional wall motion abnormalities based on a statistical model applied to multislice short-axis cardiac MR images. Suinesiaputra A, Frangi AF, Kaandorp TA, Lamb HJ, Bax JJ, Reiber JH, Lelieveldt BP

In this paper, a statistical shape analysis method for myocardial contraction is presented that was built to detect and locate regional wall motion abnormalities (RWMA). For each slice level (base, middle, and apex), 44 short-axis magnetic resonance images were selected from healthy volunteers to train a statistical model of normal myocardial contraction using independent component analysis (ICA). A classification algorithm was constructed from the ICA components to automatically detect and loca... Abstract

Cited 16 times since 2009 (1 per year) source: EuropePMC

European heart journal, Volume 30, Issue 7, 7 1 2009, Pages 797-804 Pressure-volume loop analysis during implantation of biventricular pacemaker/cardiac resynchronization therapy device to optimize right and left ventricular pacing sites. Delnoy PP, Ottervanger JP, Luttikhuis HO, Vos DH, Elvan A, Ramdat Misier AR, Beukema WP, Steendijk P, van Hemel NM

Aims: To evaluate the clinical utility of pressure-volume loop analyses during pacemaker/implantable cardioverter defibrillator (ICD) implantations to assess the optimal right ventricular (RV) and/or left ventricular (LV) lead position. Methods and results: 29 patients with heart failure and chronic RV apical pacing were studied. Stroke work (SW), LV ejection fraction (LVEF), cardiac output (CO), and LV dP/dt(max) were assessed using a conductance catheter in the LV during RV apical, RV outflow... Abstract

Cited 11 times since 2009 (0.7 per year) source: EuropePMC

Preventive veterinary medicine, Volume 89, Issue 1-2, 7 1 2009, Pages 1-7 Economic and epidemiological evaluation of Salmonella control in Dutch dairy herds. Bergevoet RH, van Schaik G, Veling J, Backus GB, Franken P

This paper presents an analysis of a Salmonella control program for Dutch dairy herds. Salmonella control strategies were evaluated using a computer-based model consisting of an epidemiological module and an economics module. The epidemiological module is a state transition model of the infectivity of a herd, with the unit of analysis being the individual farm. The probability of a herd going from one state in the model to another state was derived from biological characteristics of Salmonella i... Abstract

Cited 36 times since 2009 (2.2 per year) source: EuropePMC

The American journal of cardiology, Volume 103, Issue 7, 7 1 2009, Pages 897-901 Long-term outcome of prophylactic coronary revascularization in cardiac high-risk patients undergoing major vascular surgery (from the randomized DECREASE-V Pilot Study). Schouten O, van Kuijk JP, Flu WJ, Winkel TA, Welten GM, Boersma E, Verhagen HJ, Bax JJ, Poldermans D, DECREASE Study Group

Prophylactic coronary revascularization in vascular surgery patients with extensive coronary artery disease was not associated with an improved immediate postoperative outcome. However, the potential long-term benefit was unknown. This study was performed to assess the long-term benefit of prophylactic coronary revascularization in these patients. Of 1,880 patients scheduled for major vascular surgery, 430 had > or =3 risk factors (age >70 years, angina pectoris, myocardial infarction, hea... Abstract

Cited 81 times since 2009 (4.9 per year) source: EuropePMC

Breast cancer research and treatment, Volume 118, Issue 1, 3 1 2009, Pages 125-130 The CYP2D6*4 polymorphism affects breast cancer survival in tamoxifen users. Bijl MJ, van Schaik RH, Lammers LA, Hofman A, Vulto AG, van Gelder T, Stricker BH, Visser LE

Cytochrome P450 2D6 (CYP2D6) plays an important role in the formation of endoxifen, the active metabolite of tamoxifen. In this study the association between the most prevalent CYP2D6 null-allele in Caucasians (CYP2D6*4) and breast cancer mortality was examined among all incident users of tamoxifen in a population-based cohort study. Breast cancer mortality was significantly increased in patients with the * 4/*4 genotype (HR = 4.1, CI 95% 1.1-15.9, P = 0.041) compared to wild type patients. The... Abstract

Cited 190 times since 2009 (11.5 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 53, Issue 7, 1 1 2009, Pages 623-632 Prognostic value of multislice computed tomography and gated single-photon emission computed tomography in patients with suspected coronary artery disease. van Werkhoven JM, Schuijf JD, Gaemperli O, Jukema JW, Boersma E, Wijns W, Stolzmann P, Alkadhi H, Valenta I, Stokkel MPM, Kroft LJ, de Roos A, Pundziute G, Scholte A, van der Wall EE, Kaufmann PA, Bax JJ

Objectives: This study was designed to determine whether multislice computed tomography (MSCT) coronary angiography has incremental prognostic value over single-photon emission computed tomography myocardial perfusion imaging (MPI) in patients with suspected coronary artery disease (CAD). Background: Although MSCT is used for the detection of CAD in addition to MPI, its incremental prognostic value is unclear. Methods: In 541 patients (59% male, age 59 +/- 11 years) referred for further cardiac... Abstract

Cited 3 times since 2009 (0.2 per year) source: EuropePMC

JACC. Cardiovascular imaging, Volume 2, Issue 2, 1 1 2009, Pages 226-230 Cardiac resynchronization therapy devices guided by imaging technology. Krishnan SC, Tops LF, Bax JJ

Abstract

Cited 1 times since 2009 (0.1 per year) source: EuropePMC

Journal of the American Psychoanalytic Association, Volume 57, Issue 1, 1 1 2009, Pages 191-195 The multi-center assessment project (map): the development of a collaborative multi-center educational consortium. Cabaniss DL, Aizaga KH, O'Neil MK, Spiwack A, Van Schaik J

Abstract

Cited 2 times since 2009 (0.1 per year) source: EuropePMC

Tijdschrift voor diergeneeskunde, Volume 134, Issue 3, 1 1 2009, Pages 104-109 [Risk of Echinococcus granulosus becoming endemic in Dutch cattle]. Berends IM, Holzhauer M, van der Giessen JW, van Schaik G

Echinococcus granulosus is rare in The Netherlands and most human patients originate from southern Europe and Africa, where E. granulosus is still endemic in sheep, cattle, and pigs. Since the accession of some south-eastern European countries to the European Union, a large number of cattle have been imported from this area, according to national import data. The objective of this study was to determine the risk of re-introduction of E. granulosus in The Netherlands via the import of cattle from... Abstract

Cited 92 times since 2009 (5.6 per year) source: EuropePMC

The British journal of general practice : the journal of the Royal College of General Practitioners, Volume 59, Issue 559, 1 1 2009, Pages e51-60 Psychological treatment of depression in primary care: a meta-analysis. Cuijpers P, van Straten A, van Schaik A, Andersson G

Background: Although most depressive disorders are treated in primary care and several studies have examined the effects of psychological treatment in primary care, hardly any meta-analytic research has been conducted in which the results of these studies are integrated. Aim: To integrate the results of randomised controlled trials of psychological treatment of depression in adults in primary care, and to compare these results to psychological treatments in other settings. Design of study: A met... Abstract

Cited 51 times since 2009 (3.1 per year) source: EuropePMC

Biology letters, Volume 5, Issue 1, 1 1 2009, Pages 125-129 Why are there so few smart mammals (but so many smart birds)? Isler K, Van Schaik CP

The expensive brain hypothesis predicts an interspecific link between relative brain size and life-history pace. Indeed, animals with relatively large brains have reduced rates of growth and reproduction. However, they also have increased total lifespan. Here we show that the reduction in production with increasing brain size is not fully compensated by the increase in lifespan. Consequently, the maximum rate of population increase (rmax) is negatively correlated with brain mass. This result is... Abstract

Cited 3 times since 2009 (0.2 per year) source: EuropePMC

Current treatment options in cardiovascular medicine, Volume 11, Issue 1, 1 1 2009, Pages 33-44 Treatment recommendations to prevent myocardial ischemia and infarction in patients undergoing vascular surgery. Flu WJ, Hoeks SE, van Kuijk JP, Bax JJ, Poldermans D

During major vascular surgery (MVS), patients are at high risk for developing unrecognized myocardial infarction (MI) and myocardial ischemia. In reducing postoperative morbidity and mortality, preoperative cardiac risk stratification and adequate medical therapy play a pivotal role. Based on literature and current opinions, medical treatment should comprise at least a combination of beta-blockers, aspirin, and statins. beta-Blockers exert their beneficial effects predominantly through heart rat... Abstract

Cited 278 times since 2009 (16.8 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 53, Issue 6, 1 1 2009, Pages 483-490 Long-term prognosis after cardiac resynchronization therapy is related to the extent of left ventricular reverse remodeling at midterm follow-up. Ypenburg C, van Bommel RJ, Borleffs CJ, Bleeker GB, Boersma E, Schalij MJ, Bax JJ

Objectives: The aim of the current study was to evaluate the relation between the extent of left ventricular (LV) reverse remodeling and clinical/echocardiographic improvement after 6 months of cardiac resynchronization therapy (CRT) as well as long-term outcome. Background: Despite the current selection criteria, individual response to CRT varies significantly. Furthermore, it has been suggested that reduction in left ventricular end-systolic volume (LVESV) after CRT is related to outcome. Meth... Abstract

Cited 324 times since 2009 (19.6 per year) source: EuropePMC

Journal of the American College of Cardiology, Volume 53, Issue 6, 1 1 2009, Pages 501-510 Exenatide reduces infarct size and improves cardiac function in a porcine model of ischemia and reperfusion injury. Timmers L, Henriques JP, de Kleijn DP, Devries JH, Kemperman H, Steendijk P, Verlaan CW, Kerver M, Piek JJ, Doevendans PA, Pasterkamp G, Hoefer IE

Objectives: This study sought to examine whether exenatide is capable of reducing myocardial infarct size. Background: Exenatide is a glucagon-like peptide (GLP)-1 analogue with insulinotropic and insulinomimetic properties. Because insulin and GLP-1 have been described as reducing apoptosis, exenatide might confer cardioprotection after acute myocardial infarction (MI). Methods: Pigs were randomized to exenatide or phosphate-buffered saline (PBS) treatment after 75 min of coronary artery ligati... Abstract

Cited 8 times since 2009 (0.5 per year) source: EuropePMC

Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, Volume 16, Issue 1, 1 1 2009, Pages 105-113 Effect of stent-graft compliance on endotension after EVAR. Bosman WM, Hinnen JW, Rixen DJ, Hamming JF

Purpose: To investigate whether, and to which extent, the type of graft has influence on the pressure in the aneurysm sac. Methods: The study consisted of a dynamic and a static experiment. In the dynamic experiment, a latex aneurysm was inserted into an in-vitro circulation model, with variable (80-180 mmHg) systemic systolic pressure and a pulse pressure of 40 mmHg. Seven types of devices were used to exclude the aneurysm: a latex reference graft, 3 stentless grafts made of different fabrics,... Abstract

Cited 79 times since 2009 (4.8 per year) source: EuropePMC

Epilepsy research, Volume 84, Issue 1, 30 5 2009, Pages 56-66 Effects of SC58236, a selective COX-2 inhibitor, on epileptogenesis and spontaneous seizures in a rat model for temporal lobe epilepsy. Holtman L, van Vliet EA, van Schaik R, Queiroz CM, Aronica E, Gorter JA

Inflammation is an important biological process that is activated after status epilepticus and could be implicated in the development of epilepsy. Here we tested whether an anti-inflammatory treatment with a selective cox-2 inhibitor (SC58236) could prevent the development of epilepsy or modify seizure activity during the chronic epileptic phase. SC58236 was orally administered (10mg/kg) during the latent period for 7 days, starting 4h after electrically induced SE. Seizures were monitored using... Abstract

Cited 48 times since 2009 (2.9 per year) source: EuropePMC

Marine pollution bulletin, Volume 58, Issue 5, 29 5 2009, Pages 720-725 Bacterial flora and antibiotic resistance from eggs of green turtles Chelonia mydas: an indication of polluted effluents. Al-Bahry S, Mahmoud I, Elshafie A, Al-Harthy A, Al-Ghafri S, Al-Amri I, Alkindi A

Sea turtles migrate to various habitats where they can be exposed to different pollutants. Bacteria were collected from turtle eggs and their resistance to antibiotics was used as pollutant bio-indicators of contaminated effluents. Eggs were collected randomly from turtles when they were laying their eggs. A total of 90 eggs were collected and placed into sterile plastic bags (3 eggs/turtle) during June-December of 2003. The bacteria located in the eggshell, albumen and yolk were examined, and 4... Abstract

Cited 7 times since 2009 (0.4 per year) source: EuropePMC

European journal of radiology, Volume 74, Issue 1, 29 5 2009, Pages 67-70 Improving the false-negative rate of CT in acute appendicitis-Reassessment of CT images by body imaging radiologists: a blinded prospective study. Poortman P, Lohle PN, Schoemaker CM, Cuesta MA, Oostvogel HJ, de Lange-de Klerk ES, Hamming JF

Purpose: To compare the accuracy of computed tomography (CT) analyzed by individual radiology staff members and body imaging radiologists in a non-academic teaching hospital for the diagnosis of acute appendicitis. Patients and methods: In a prospective study 199 patients with suspected acute appendicitis were examined with unenhanced CT. CT images were pre-operatively analyzed by one of the 12 members of the radiology staff. In a later stage two body imaging radiologist reassessed all CT images... Abstract

Cited 49 times since 2009 (3 per year) source: EuropePMC

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, Volume 12, Issue 3, 27 4 2009, Pages 179-186 Colonic diverticulitis: a prospective analysis of diagnostic accuracy and clinical decision-making. Toorenvliet BR, Bakker RF, Breslau PJ, Merkus JW, Hamming JF

Objective: To evaluate the diagnostic accuracy of clinical evaluation and cross-sectional imaging modalities such as ultrasound and computed tomography for patients with suspected colonic diverticulitis and to determine the value of these examinations in clinical decision-making. Method: A prospective analysis was conducted of 802 consecutive patients that presented with abdominal pain at the emergency department. Initial clinical diagnoses and management proposals were compared to the final dia... Abstract

Cited 59 times since 2009 (3.6 per year) source: EuropePMC

Circulation. Cardiovascular imaging, Volume 2, Issue 2, 26 4 2009, Pages 100-106 Prevalence of coronary artery disease assessed by multislice computed tomography coronary angiography in patients with paroxysmal or persistent atrial fibrillation. Nucifora G, Schuijf JD, Tops LF, van Werkhoven JM, Kajander S, Jukema JW, Schreur JH, Heijenbrok MW, Trines SA, Gaemperli O, Turta O, Kaufmann PA, Knuuti J, Schalij MJ, Bax JJ

Background: Although atrial fibrillation (AF) has been linked to underlying coronary artery disease (CAD), data supporting this association have been based on ECG and clinical history for the definition of CAD rather than direct visualization of atherosclerosis. Methods and results: The prevalence of CAD among patients with paroxysmal or persistent AF and without history of CAD was evaluated using multislice computed tomography. Multislice computed tomography was performed in 150 patients with A... Abstract