9618 results
Tijdschrift voor diergeneeskunde,
Volume 129, Issue 24, 1 1 2004, Pages 850-851
[Veterinary practice certification and recognition (II)].
van Schaik AM
Abstract
Cited 34 times since 2004 (1.6 per year)
source: EuropePMC
Journal of neurology,
Volume 251, Issue 12, 1 1 2004, Pages 1491-1497
Clinical disease severity and axonal dysfunction in hereditary motor and sensory neuropathy Ia.
Verhamme C, van Schaik IN, Koelman JH, de Haan RJ, Vermeulen M, de Visser M
Background: Hereditary motor and sensory neuropathy type Ia (HMSN Ia) is known as a primarily demyelinating peripheral nerve disease. Evidence is accumulating that axonal involvement determines the course of the disease process. Methods: Fifty-one patients were investigated. Physical disability and impairments were scored. Nerve conduction velocities (NCVs) were used as indirect measures for myelination status and compound muscle/sensory nerve action potential (CMAP/SNAP) amplitudes served as in...
Abstract
Cited 97 times since 2004 (4.7 per year)
source: EuropePMC
Clinical cancer research : an official journal of the American Association for Cancer Research,
Volume 10, Issue 24, 1 1 2004, Pages 8341-8350
Factors affecting cytochrome P-450 3A activity in cancer patients.
Baker SD, van Schaik RH, Rivory LP, Ten Tije AJ, Dinh K, Graveland WJ, Schenk PW, Charles KA, Clarke SJ, Carducci MA, McGuire WP, Dawkins F, Gelderblom H, Verweij J, Sparreboom A
Purpose: The purpose is to identify the demographic, physiologic, and inheritable factors that influence CYP3A activity in cancer patients. Experimental design: A total of 134 patients (62 females; age range, 26 to 83 years) underwent the erythromycin breath test as a phenotyping probe of CYP3A. Genomic DNA was screened for six variants of suspected functional relevance in CYP3A4 (CYP3A4*1B, CYP3A4*6, CYP3A4*17, and CYP3A4*18) and CYP3A5 (CYP3A5*3C and CYP3A5*6). Results: CYP3A activity (AUC(0-4...
Abstract
Cited 27 times since 2004 (1.3 per year)
source: EuropePMC
Inorganic chemistry,
Volume 43, Issue 26, 1 1 2004, Pages 8461-8469
Rare-earth quinolinates: infrared-emitting molecular materials with a rich structural chemistry.
Van Deun R, Fias P, Nockemann P, Schepers A, Parac-Vogt TN, Van Hecke K, Van Meervelt L, Binnemans K
Near-infrared-emitting rare-earth chelates based on 8-hydroxyquinoline have appeared frequently in recent literature, because they are promising candidates for active components in near-infrared-luminescent optical devices, such as optical amplifiers, organic light-emitting diodes, .... Unfortunately, the absence of a full structural investigation of these rare-earth quinolinates is hampering the further development of rare-earth quinolinate based materials, because the luminescence output canno...
Abstract
Cited 15 times since 2004 (0.7 per year)
source: EuropePMC
Trends in biotechnology,
Volume 22, Issue 12, 1 1 2004, Pages 653-660
Impact of genomics on microbial food safety.
Abee T, van Schaik W, Siezen RJ
Genome sequences are now available for many of the microbes that cause food-borne diseases. The information contained in pathogen genome sequences, together with the development of themed and whole-genome DNA microarrays and improved proteomics techniques, might provide tools for the rapid detection and identification of such organisms, for assessing their biological diversity and for understanding their ability to respond to stress. The genomic information also provides insight into the metabol...
Abstract
Cited 8 times since 2004 (0.4 per year)
source: EuropePMC
Gene,
Volume 343, Issue 1, 1 1 2004, Pages 91-97
Efficient somatic gene targeting in the lymphoid human cell line DG75.
Feederle R, Delecluse HJ, Rouault JP, Schepers A, Hammerschmidt W
Among the different approaches used to define the function of a protein of interest, alteration and/or deletion of its encoding gene is the most direct strategy. Homologous recombination between the chromosomal gene locus and an appropriately designed targeting vector results in an alteration or knockout of the gene of interest. Homologous recombination is easily performed in yeast or in murine embryonic stem cells, but is cumbersome in more differentiated and diploid somatic cell lines. Here we...
Abstract
Cited 2 times since 2004 (0.1 per year)
source: EuropePMC
The Journal of parasitology,
Volume 90, Issue 6, 1 1 2004, Pages 1279-1287
Transition models to assess risk factors for new and persistent trypanosome infections in cattle-analysis of longitudinal data from the Ghibe Valley, southwest Ethiopia.
Schukken YH, van Schaik G, McDermott JJ, Rowlands GJ, Nagda SM, Mulatu W, d'Ieteren GD
The objective of this study was to apply transition models to distinguish between factors associated with both incident and persistent trypanosome infections. Data collected from 1561 cattle were analyzed from a long-term study involving 8 herds in which both trypanosome infections (a total of 56,931 cattle sampling-months) and tsetse (Glossina spp.) challenge were monitored monthly from March 1986 to March 1998. Both pour-on and insecticide-target tsetse control programs and mass treatment with...
Abstract
Cited 28 times since 2004 (1.4 per year)
source: EuropePMC
European journal of radiology,
Volume 52, Issue 3, 1 1 2004, Pages 240-245
The value of MR angiography techniques in the detection of head and neck paragangliomas.
van den Berg R, Schepers A, de Bruïne FT, Liauw L, Mertens BJ, van der Mey AG, van Buchem MA
Objective: The objective of this study was to compare three-dimensional phase-contrast angiography (3D PCA), 2D time-of-flight (2D TOF), and 3D TOF magnetic resonance (MR) angiography and a proton density weighted technique in terms of their ability to detect head and neck paragangliomas. Materials and methods: 14 patients with 29 paragangliomas were examined at 1.5 T. Three MR angiography sequences (3D PCA, 2D TOF, and multi-slab 3D TOF) and a proton density (PD) weighted sequence were reviewed...
Abstract
Tijdschrift voor diergeneeskunde,
Volume 129, Issue 24, 1 1 2004, Pages 848
[The eye of the storm...].
van Schaik AR
Abstract
Cited 119 times since 2004 (5.7 per year)
source: EuropePMC
Clinical pharmacology and therapeutics,
Volume 76, Issue 6, 1 1 2004, Pages 545-556
Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes.
Hesselink DA, van Gelder T, van Schaik RH, Balk AH, van der Heiden IP, van Dam T, van der Werf M, Weimar W, Mathot RA
Objective: Our objective was to determine the relationship between single nucleotide polymorphisms (SNPs) in the multidrug resistance 1 (MDR-1) gene and the cytochrome P450 (CYP) genes CYP3A4 and CYP3A5 and the pharmacokinetics of cyclosporine (INN, ciclosporin). Methods: Cyclosporine pharmacokinetics of 151 kidney and heart transplant recipients undergoing maintenance therapy was described by use of nonlinear mixed-effects modeling (NONMEM) according to a 2-compartment pharmacokinetic model wit...
Abstract
Cited 122 times since 2004 (5.9 per year)
source: EuropePMC
Journal of human evolution,
Volume 47, Issue 6, 1 1 2004, Pages 385-398
Life history of wild Sumatran orangutans (Pongo abelii).
Wich SA, Utami-Atmoko SS, Setia TM, Rijksen HD, Schürmann C, van Hooff JA, van Schaik CP
We present life history data on wild Sumatran orangutans gleaned from a 32-year and a 5.5-year study. Estimated age at first reproduction was 15.4 years. At 9.3 years, the average interbirth interval for this population is the longest ever recorded for any great ape population, significantly longer than that of a Bornean orangutan population. We find that age-specific mortality of Sumatran orangutans does not differ between sexes and is significantly lower than that of wild chimpanzees. We concl...
Abstract
Cited 63 times since 2004 (3 per year)
source: EuropePMC
Diabetes care,
Volume 27, Issue 12, 1 1 2004, Pages 2887-2892
Two-year statin therapy does not alter the progression of intima-media thickness in patients with type 2 diabetes without manifest cardiovascular disease.
Beishuizen ED, van de Ree MA, Jukema JW, Tamsma JT, van der Vijver JC, Meinders AE, Putter H, Huisman MV
Objective: Cardiovascular disease (CVD) is the most important cause of mortality in patients with type 2 diabetes. We aimed to determine the effect of statin therapy versus placebo on the progression of carotid intima-media thickness (IMT) in type 2 diabetic patients without manifest CVD. Research design and methods: A randomized, placebo-controlled, double-blind clinical trial was performed in 250 patients with type 2 diabetes. Patients were given either 0.4 mg cerivastatin or placebo daily. In...
Abstract
Cited 4 times since 2004 (0.2 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 27, Issue 12, 1 1 2004, Pages 1603-1609
Hypertensive stress increases dispersion of repolarization.
Van Huysduynen BH, Swenne CA, Van Eck HJ, Kors JA, Schoneveld AL, Van De Vooren H, Schiereck P, Schalij MJ, Van Der Wall EE
Several electrocardiographic indices for repolarization heterogeneity have been proposed previously. The behavior of these indices under two different stressors at the same heart rate (i.e., normotensive gravitational stress, and hypertensive isometric stress) was studied. ECG and blood pressure were recorded in 56 healthy men during rest (sitting with horizontal legs), hypertensive stress (performing handgrip), and normotensive stress (sitting with lowered legs). During both stressors, heart ra...
Abstract
Cited 60 times since 2004 (2.9 per year)
source: EuropePMC
Journal of virology,
Volume 78, Issue 23, 1 1 2004, Pages 13019-13027
Structural protein requirements in equine arteritis virus assembly.
Wieringa R, de Vries AA, van der Meulen J, Godeke GJ, Onderwater JJ, van Tol H, Koerten HK, Mommaas AM, Snijder EJ, Rottier PJ
Equine arteritis virus (EAV) is an enveloped, positive-stranded RNA virus belonging to the family Arteriviridae of the order Nidovirales. EAV particles contain seven structural proteins: the nucleocapsid protein N, the unglycosylated envelope proteins M and E, and the N-glycosylated membrane proteins GP(2b) (previously named G(S)), GP(3), GP(4), and GP(5) (previously named G(L)). Proteins N, M, and GP(5) are major virion components, E occurs in virus particles in intermediate amounts, and GP(4),...
Abstract
Cited 30 times since 2004 (1.4 per year)
source: EuropePMC
Endocrinology,
Volume 146, Issue 3, 18 3 2004, Pages 1418-1427
Daily variations in type II iodothyronine deiodinase activity in the rat brain as controlled by the biological clock.
Kalsbeek A, Buijs RM, van Schaik R, Kaptein E, Visser TJ, Doulabi BZ, Fliers E
Type II deiodinase (D2) plays a key role in regulating thyroid hormone-dependent processes in, among others, the central nervous system (CNS) by accelerating the intracellular conversion of T4 into active T3. Just like the well-known daily rhythm of the hormones of the hypothalamo-pituitary-thyroid axis, D2 activity also appears to show daily variations. However, the mechanisms involved in generating these daily variations, especially in the CNS, are not known. Therefore, we decided to investiga...
Abstract
Cited 41 times since 2004 (2 per year)
source: EuropePMC
Circulation,
Volume 110, Issue 20, 8 2 2004, Pages 3187-3192
Left atrial tachycardia originating from the mitral annulus-aorta junction.
Gonzalez MD, Contreras LJ, Jongbloed MR, Rivera J, Donahue TP, Curtis AB, Bailey MS, Conti JB, Fishman GI, Schalij MJ, Gittenberger-de Groot AC
Background: At the mitral annulus-aorta (MA-Ao) junction, the left atrium is continuous through the subaortic curtain with the musculature of the anterior mitral leaflet. Under experimental conditions, this region can generate abnormal electrical activity. In patients with left atrial tachycardia, we investigated whether this region could be the source of this arrhythmia. Methods and results: In 10 (28%) of 35 consecutive patients with left atrial tachycardia, the arrhythmia originated from the...
Abstract
Cited 27 times since 2004 (1.3 per year)
source: EuropePMC
Pediatric research,
Volume 57, Issue 1, 5 1 2004, Pages 16-21
Systolic and diastolic ventricular function assessed by pressure-volume loops in the stage 21 venous clipped chick embryo.
Stekelenburg-de Vos S, Steendijk P, Ursem NT, Wladimiroff JW, Delfos R, Poelmann RE
Cardiac pressure-volume relations enable quantification of intrinsic ventricular diastolic and systolic properties independent of loading conditions. The use of pressure-volume loop analysis in early stages of development could contribute to a better understanding of the relationship between hemodynamics and cardiac morphogenesis. The venous clip model is an intervention model for the chick embryo in which permanent obstruction of the right lateral vitelline vein temporarily reduces the mechanic...
Abstract
Cited 728 times since 2004 (35 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 44, Issue 9, 1 1 2004, Pages 1834-1840
Left ventricular dyssynchrony predicts response and prognosis after cardiac resynchronization therapy.
Bax JJ, Bleeker GB, Marwick TH, Molhoek SG, Boersma E, Steendijk P, van der Wall EE, Schalij MJ
Objectives: This study was designed to predict the response and prognosis after cardiac resynchronization therapy (CRT) in patients with end-stage heart failure (HF). Background: Cardiac resynchronization therapy improves HF symptoms, exercise capacity, and left ventricular (LV) function. Because not all patients respond, preimplantation identification of responders is needed. In the present study, response to CRT was predicted by the presence of LV dyssynchrony assessed by tissue Doppler imagin...
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 12, Issue Suppl 2, 1 1 2004, Pages 25-26
Caring for patients with type 2 diabetes - a responsibility to be shared between cardiologists and diabetologists: Munich, 30 August 2004.
Beeres SL
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 12, Issue Suppl 2, 1 1 2004, Pages 17-18
INTERHEART - a global study of risk factors for acute myocardial infarction in 52 countries: Munich, 29 August 2004.
Beeres SL
Abstract
