Research

Publications

Below you can find a list of our published research.

9618 results

Cited 23 times since 2010 (1.5 per year) source: EuropePMC

Journal of applied microbiology, Volume 108, Issue 1, 1 1 2010, Pages 104-114 Mobility and survival of Salmonella Typhimurium and human adenovirus from spiked sewage sludge applied to soil columns. Horswell J, Hewitt J, Prosser J, Van Schaik A, Croucher D, Macdonald C, Burford P, Susarla P, Bickers P, Speir T

Aims: This study investigated the survival and transport of sewage sludge-borne pathogenic organisms in soils. Methods and results: Undisturbed soil cores were treated with Salmonella enterica ssp. enterica serovar Typhimurium-lux (STM-lux) and human adenovirus (HAdV)-spiked sewage sludge. Following an artificial rainfall event, these pathogens were analysed in the leachate and soil sampled from different depths (0-5 cm, 5-10 cm and 10-20 cm) after 24 h, 1 and 2 months. Significantly more STM-lu... Abstract

Cited 14 times since 2010 (0.9 per year) source: EuropePMC

Journal of social work in end-of-life & palliative care, Volume 6, Issue 3-4, 1 1 2010, Pages 236-255 Development of a Web-based educational intervention to improve cross-cultural communication among hospice providers. Doorenbos AZ, Lindhorst T, Schim SM, Van Schaik E, Demiris G, Wechkin HA, Curtis JR

In this article, the authors describe the theoretical foundation, development, and content of a Web-based educational intervention to improve cross-cultural communication about end-of-life concerns and report on the preliminary evaluation of this intervention using a qualitative study design. The data were collected with non-structured questions in a convenience sample of 21 hospice providers. Participants reported that they found the training appropriate and useful. Participants also reported f... Abstract

Cited 81 times since 2010 (5.2 per year) source: EuropePMC

American journal of primatology, Volume 72, Issue 1, 1 1 2010, Pages 62-71 Social learning of diet and foraging skills by wild immature Bornean orangutans: implications for culture. Jaeggi AV, Dunkel LP, Van Noordwijk MA, Wich SA, Sura AA, Van Schaik CP

Studies of social learning in the wild are important to complement findings from experiments in captivity. In this field study, immature Bornean orangutans rarely foraged independently but consistently followed their mothers' choices. Their diets were essentially identical to their mothers' even though not all mothers had the same diet. This suggests vertical transmission of diet by enhancement. Also, immatures selectively observed their mothers during extractive foraging, which increa... Abstract

Cited 12 times since 2010 (0.8 per year) source: EuropePMC

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Volume 26, Issue 6, 1 1 2010, Pages 999-1010 Integrin stimulation favors uptake of macromolecules by cardiomyocytes in vitro. Swildens J, de Vries AA, Li Z, Umar S, Atsma DE, Schalij MJ, van der Laarse A

Previously, our research group showed that integrin stimulation induces release of cardiac troponin I from viable neonatal rat ventricular cardiomyocytes (NRCMs), but would it also stimulate uptake of exogenous macromolecules? For this purpose, beating NRCMs were incubated without or with an RGD motif-containing peptide (GRGDS) to stimulate integrins in the presence of Texas Red-conjugated ovalbumin (OTR; 45 kDa) or dextran (DTR; 70 kDa). After incubation periods of 8, 16 and 24 hours endocytosi... Abstract

Cited 7 times since 2010 (0.4 per year) source: EuropePMC

Haemophilia : the official journal of the World Federation of Hemophilia, Volume 16, Issue 1, 1 1 2010, Pages e210-5 Thrombin generation in vitro in the presence of by-passing agents in siblings with severe haemophilia A. Klintman J, Berntorp E, Astermark J, MIBS Study Group

Previous data have shown an inter-individual difference in the thrombin generating capacity in vitro as well as phenotypic bleeding pattern among patients with severe haemophilia A (FVIII:C activity below 1%). The reason for this is not known. In addition, there are no reports on how thrombin generation may correlate between siblings. In this study, we evaluated and compared thrombin generation in vitro using plasma samples in the presence of by-passing agents (FEIBA and NovoSeven) in 21 unrelat... Abstract

Journal of the American College of Cardiology, Volume 55, Issue 4, 1 1 2010, Pages 380-407 Highlights of the Year in JACC 2009. DeMaria AN, Bax JJ, Ben-Yehuda O, Feld GK, Greenberg BH, Hall J, Hlatky M, Lew WY, Lima JA, Maisel AS, Narayan SM, Nissen S, Sahn DJ, Tsimikas S

Abstract

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 17, Issue 1, 1 1 2010, Pages 97-105 Highlights of the 2009 Scientific Session of the American Society of Nuclear Cardiology: Minneapolis, Minnesota, October 1-4, 2009. Russell RR, Abbott BG, Arrighi JA, Blankstein R, Cohen MC, Faber TL, Mieres JH, Miller TD, Tilkemeier PL, Travin MI, Bax JJ

Abstract

Tuberkuloz ve toraks, Volume 58, Issue 4, 1 1 2010, Pages 401-407 [Impaired myocardial performance in sarcoidosis]. Aydın Kaderli A, Güllülü S, Coşkun F, Yılmaz D, Uzaslan E

Despite myocardial sarcoid involvement has been reported in 20-27% in autopsy series, only 5% of the patients are clinically symptomatic. This study was planned to evaluate right and left ventricular functions in patients with early stage sarcoidosis (stage I and II) without any findings of cardiac involvement with Tei index which globally shows systolic and diastolic functions of the ventricles was used. Seventy-two patients under follow-up for sarcoidosis without cardiac involvement (53 women,... Abstract

Cited 5 times since 2010 (0.3 per year) source: EuropePMC

Asian Pacific journal of cancer prevention : APJCP, Volume 11, Issue 1, 1 1 2010, Pages 53-56 Relations between breast and cervical cancer prevention behaviour of female students at a school of health and their healthy life style. Malak AT, Yilmaz D, Tuna A, Gümüs AB, Turgay AS

Regular breast self-examination (BSE) and pap-smear tests are the two of the positive heath behaviors for improving, promoting and protecting the health of adolescent girls. The present quasi-experimental research was carried out with the purpose of analyzing the relations between breast and cervical cancer prevention behavior of female students at a School of Health and their health lifestyle. The research was conducted at Canakkale Onsekiz Mart University School of Health between November 2008... Abstract

Nederlands tijdschrift voor geneeskunde, Volume 154, 1 1 2010, Pages A1578 [Trainee feedback: trainer assessment]. Hamming JF, de Leede BJ

The quality of medical specialty education depends highly on the trainers, i.e. the specialists. Trainees are very important in the assessment of their trainers because they continuously undergo all the important aspects of the training. Currently, periodical announced visits take place, creating a formal atmosphere. A regular, semi-structured questionnaire for the trainees would be a better way of evaluating the program. Additionally there should be a thorough follow-up leading to a system with... Abstract

Cited 1 times since 2010 (0.1 per year) source: EuropePMC

Innovations (Philadelphia, Pa.), Volume 5, Issue 1, 1 1 2010, Pages 16-21 Resizable ventricular patch plasty in the porcine left ventricle: a pilot study. Huijgen WH, Gründeman PF, van der Spoel T, Cramer MJ, Steendijk P, Klautz RJ, van Herwerden LA

Objective: : Endoventricular circular patch plasty is a method used to reconstruct the ventricular cavity in patients with (post) ischemic left ventricular aneurysm or global dilatation. However, late redilatation with mitral regurgitation has been reported, in which postoperative apex shape seems to play an important role. We studied the feasibility of ventricular volume downsizing with a variably shaped patch in porcine hearts. Methods: : In five in vitro and two acute animal experiments, a dy... Abstract

Cited 26 times since 2010 (1.7 per year) source: EuropePMC

Expert review of cardiovascular therapy, Volume 8, Issue 1, 1 1 2010, Pages 113-123 Transcatheter aortic valve implantation: role of multimodality cardiac imaging. Delgado V, Ng AC, Shanks M, van der Kley F, Schuijf JD, van de Veire NR, Kroft L, de Roos A, Schalij MJ, Bax JJ

Current evidence based on more than 8000 high-risk patients with severe aortic stenosis has demonstrated that transcatheter aortic valve implantation (TAVI) is a feasible alternative to surgical aortic valve replacement in selected patients. Despite current promising results on hemodynamic and clinical improvements, there are several unresolved safety issues, such as the frequency of vascular complications, postprocedural paravalvular leak, atrioventricular heart block and stroke. Multimodality... Abstract

Cited 1 times since 2009 (0.1 per year) source: EuropePMC

The international journal of cardiovascular imaging, Volume 26, Issue 2, 29 5 2010, Pages 199-202 Cardiac resynchronization therapy; evaluation by advanced imaging techniques. van der Wall EE, Schalij MJ, Bax JJ

Abstract

Cited 50 times since 2009 (3.2 per year) source: EuropePMC

European heart journal, Volume 31, Issue 8, 27 4 2010, Pages 992-999 Long-term prognosis of patients with peripheral arterial disease with or without polyvascular atherosclerotic disease. van Kuijk JP, Flu WJ, Welten GM, Hoeks SE, Chonchol M, Vidakovic R, Verhagen HJ, Bax JJ, Poldermans D

Aims: Patients with peripheral atherosclerotic disease often have multiple affected vascular beds (AVB), however, data on long-term follow-up and medical therapy are scarce. We assessed the prevalence and prognostic implications of polyvascular disease on long-term outcome in symptomatic peripheral arterial disease (PAD) patients. Methods and results: Two thousand nine hundred and thirty-three consecutive patients were screened prior to surgery for concomitant documented cerebrovascular disease... Abstract

Cited 1 times since 2009 (0.1 per year) source: EuropePMC

The international journal of cardiovascular imaging, Volume 26, Issue 3, 24 4 2009, Pages 355-358 CT perfusion angiography; beware of artifacts! van der Wall EE, Schuijf JD, Bax JJ, Jukema JW, Schalij MJ

Abstract

Cited 12 times since 2009 (0.8 per year) source: EuropePMC

Journal of vascular surgery, Volume 51, Issue 2, 24 4 2009, Pages 429-437 In vivo suppression of vein graft disease by nonviral, electroporation-mediated, gene transfer of tissue inhibitor of metalloproteinase-1 linked to the amino terminal fragment of urokinase (TIMP-1.ATF), a cell-surface directed matrix metalloproteinase inhibitor. Eefting D, de Vries MR, Grimbergen JM, Karper JC, van Bockel JH, Quax PH

Background: Smooth muscle cell (SMC) migration and proliferation are important in the development of intimal hyperplasia, the major cause of vein graft failure. Proteases of the plasminogen activator (PA) system and of the matrix metalloproteinase (MMP) system are pivotal in extracellular matrix degradation and, by that, SMC migration. Previously, we demonstrated that inhibition of both protease systems simultaneously with viral gene delivery of the hybrid protein TIMP-1.ATF, consisting of the t... Abstract

Cited 26 times since 2009 (1.7 per year) source: EuropePMC

Journal of virology, Volume 84, Issue 5, 23 4 2009, Pages 2533-2546 The latent origin of replication of Epstein-Barr virus directs viral genomes to active regions of the nucleus. Deutsch MJ, Ott E, Papior P, Schepers A

The Epstein-Barr virus efficiently infects human B cells. The EBV genome is maintained extrachromosomally and replicates synchronously with the host's chromosomes. The latent origin of replication (oriP) guarantees plasmid stability by mediating two basic functions: replication and segregation of the viral genome. While the segregation process of EBV genomes is well understood, little is known about its chromatin association and nuclear distribution during interphase. Here, we analyzed the... Abstract

Cited 31 times since 2009 (2 per year) source: EuropePMC

Arteriosclerosis, thrombosis, and vascular biology, Volume 30, Issue 3, 23 4 2009, Pages 605-611 Activation of hemostasis and decline in cognitive function in older people. Stott DJ, Robertson M, Rumley A, Welsh P, Sattar N, Packard CJ, Shepherd J, Trompet S, Westendorp RG, de Craen AJ, Jukema JW, Buckley B, Ford I, Lowe GD

Objective: To determine whether activation of hemostatic function (thrombosis and fibrinolysis) is associated with cognitive decline in older people. Methods and results: We studied 5804 people (age, 70-82 years) in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Mean follow-up was 3.2 years, including annual measurement of speed of information processing (letter, digit coding, and Stroop), verbal memory (picture-word naming), and basic and instrumental activities of daily... Abstract

Cited 6 times since 2009 (0.4 per year) source: EuropePMC

Brain & development, Volume 32, Issue 6, 23 4 2009, Pages 467-471 Tau proteins in the cerebrospinal fluid of patients with subacute sclerosing panencephalitis. Yuksel D, Yilmaz D, Uyar NY, Senbil N, Gurer Y, Anlar B

Neurodegenerative diseases characterized by cytoskeletal deformation and neurofibrillary tangles are associated with altered levels of tau and related proteins in cerebrospinal fluid (CSF). Neuronal or glial fibrillary tangles have been shown in 20% of subacute sclerosing panencephalitis (SSPE) patients. We therefore investigated CSF samples from 60 newly diagnosed SSPE and 31 neurological control patients for total tau (t-tau), phosphorylated tau (p-tau), and S100-B levels by ELISA. There was n... Abstract

Cited 20 times since 2009 (1.3 per year) source: EuropePMC

Atherosclerosis, Volume 210, Issue 2, 22 4 2009, Pages 596-601 Metabolic syndrome is an independent predictor of cardiovascular events in high-risk patients with occlusive and aneurysmatic peripheral arterial disease. van Kuijk JP, Flu WJ, Chonchol M, Bax JJ, Verhagen HJ, Poldermans D

Objective: Metabolic syndrome (MetSyn) is a well-known risk factor for cardiovascular (CV) disease in the general population; however, the additional predictive value for CV events in high-risk patients with peripheral arterial disease (PAD) is unknown. The aims of the current study were to assess and compare: (1) prevalence of MetSyn, and (2) predictive value of MetSyn for CV events, in patients with either occlusive or aneurysmatic PAD. Methods: We screened 2069 patients scheduled for lower oc... Abstract