9618 results
Cited 5 times since 2005 (0.2 per year)
source: EuropePMC
EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology,
Volume 1, Issue 2, 1 1 2005, Pages 236-243
Inhibition of intimal hyperplasia by the tetracycline derived mmp inhibitor doxycycline in vein graft disease in vitro and in vivo.
Lardenoye JH, de Vries MR, Deckers M, van Lent N, Hanemaaijer R, van Bockel JH, Quax PH
Aims: Intimal hyperplasia, characterised by smooth muscle cell migration and proliferation, requires extracellular matrix degradation which is mediated by matrix metalloproteinases (MMPs). In this study, the effect of tetracycline derived doxycycline, a specific MMP inhibitor of both activity and synthesis, on intimal hyperplasia in vitro and in vivo was assessed. Methods and results: Segments of human saphenous veins were cultured for 4 weeks in absence or presence of doxycycline (10microg/ml)...
Abstract
Cited 42 times since 2005 (2.1 per year)
source: EuropePMC
Human molecular genetics,
Volume 14, Issue 18, 27 4 2005, Pages 2607-2618
Functional interaction between -629C/A, -971G/A and -1337C/T polymorphisms in the CETP gene is a major determinant of promoter activity and plasma CETP concentration in the REGRESS Study.
Frisdal E, Klerkx AH, Le Goff W, Tanck MW, Lagarde JP, Jukema JW, Kastelein JJ, Chapman MJ, Guerin M
Cholesteryl ester transfer protein (CETP) plays a key role in the determination of high-density lipoprotein (HDL) levels via its action on intravascular HDL metabolism. The TaqIB polymorphism of the CETP gene is associated with plasma CETP and high-density lipoprotein cholesterol (HDL-C) levels and with premature coronary artery disease. Such associations appear to result from linkage disequilibrium between TaqIB and other functional polymorphisms. To date, only one functional promoter variant,...
Abstract
Cited 18 times since 2005 (0.9 per year)
source: EuropePMC
Cardiovascular research,
Volume 68, Issue 3, 15 3 2005, Pages 415-424
Histopathologic alterations following local delivery of dexamethasone to inhibit restenosis in murine arteries.
Pires NM, Schepers A, van der Hoeven BL, de Vries MR, Boesten LS, Jukema JW, Quax PH
Objective: Dexamethasone-eluting stents are currently under evaluation to prevent post-angioplasty restenosis. The efficacy and safety of dexamethasone as an anti-restenotic agent is still unclear. We assess the effect of perivascular delivery of dexamethasone on vascular pathology in a mouse model of restenosis. Methods and results: In this study we investigate the ability of both systemic and local dexamethasone treatment to inhibit neointima formation after cuff placement around C57BL/6 mouse...
Abstract
Cited 39 times since 2005 (1.9 per year)
source: EuropePMC
Diabetes care,
Volume 28, Issue 7, 1 1 2005, Pages 1668-1674
The effect of statin therapy on endothelial function in type 2 diabetes without manifest cardiovascular disease.
Beishuizen ED, Tamsma JT, Jukema JW, van de Ree MA, van der Vijver JC, Meinders AE, Huisman MV
Objective: Cardiovascular disease (CVD) is the most important cause of mortality in patients with type 2 diabetes and is preceded by endothelial dysfunction. Flow-mediated dilation (FMD) is a noninvasive technique for measuring endothelial dysfunction. We aimed to determine the effect of long-term statin therapy versus placebo on FMD in patients with type 2 diabetes without manifest CVD. Research design and methods: A randomized, placebo-controlled, double-blind trial was performed with 250 type...
Abstract
Cited 11 times since 2005 (0.5 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 130, Issue 1, 1 1 2005, Pages 33-40
Acute hemodynamic effects of restrictive mitral annuloplasty in patients with end-stage heart failure: analysis by pressure-volume relations.
Tulner SA, Steendijk P, Klautz RJ, Bax JJ, Versteegh MI, van der Wall EE, Dion RA
Objective: Recent studies show beneficial long-term effects of restrictive mitral annuloplasty in patients with end-stage heart failure. However, concerns are raised about possible adverse effects on early postoperative systolic and diastolic function, which might limit application of this approach in patients with heart failure. Therefore we evaluated the acute effects of restrictive mitral annuloplasty on left ventricular function by using load-independent pressure-volume relations. Methods: I...
Abstract
Cited 8 times since 2005 (0.4 per year)
source: EuropePMC
Diabetes care,
Volume 28, Issue 7, 1 1 2005, Pages 1675-1679
No effect of statin therapy on silent myocardial ischemia in patients with type 2 diabetes without manifest cardiovascular disease.
Beishuizen ED, Jukema JW, Tamsma JT, van de Ree MA, van der Vijver JC, Putter H, Maan AC, Meinders AE, Huisman MV
Objective: Coronary artery disease is the most important cause of mortality in patients with type 2 diabetes. We aimed to determine the prevalence of silent myocardial ischemia (SMI) and the effect of statin therapy on SMI in type 2 diabetic patients without manifest cardiovascular disease. Research design and methods: A randomized, placebo-controlled, double-blind trial was performed in 250 patients with type 2 diabetes without manifest cardiovascular disease. Patients were given either 0.4 mg...
Abstract
Cited 17 times since 2005 (0.8 per year)
source: EuropePMC
The American journal of cardiology,
Volume 96, Issue 1, 1 1 2005, Pages 22-24
Effect of intracoronary aqueous oxygen on left ventricular remodeling after anterior wall ST-elevation acute myocardial infarction.
Warda HM, Bax JJ, Bosch JG, Atsma DE, Jukema JW, van der Wall EE, van der Laarse A, Schalij MJ, Oemrawsingh PV
The present report describes outcomes of randomized selective intracoronary aqueous oxygen versus standard care in patients who had acute anterior wall myocardial infarction within 6 hours of onset (n = 50). Left ventricular (LV) dimensions and function were assessed by contrast echocardiography at baseline and 1 month. It is demonstrated that aqueous oxygen prevents LV remodeling and preserves LV ejection fraction.
Abstract
Cited 25 times since 2005 (1.2 per year)
source: EuropePMC
The Journal of small animal practice,
Volume 46, Issue 7, 1 1 2005, Pages 322-326
Ultrasonographic evaluation of the thickness of the small intestinal wall in dogs with inflammatory bowel disease.
Rudorf H, van Schaik G, O'Brien RT, Brown PJ, Barr FJ, Hall EJ
Objectives: To establish whether the intestinal wall thickness, as measured ultrasonographically, is significantly increased in dogs with inflammatory bowel disease (IBD). The results would provide the information necessary to decide whether measurement of ultrasonographic wall thickness can predict IBD in dogs. Methods: The intestinal wall thickness of 75 dogs with idiopathic IBD, as measured by ultrasonography, was compared with recently published normal values. IBD was either confirmed histol...
Abstract
Cited 84 times since 2005 (4.2 per year)
source: EuropePMC
The Journal of the Acoustical Society of America,
Volume 118, Issue 1, 1 1 2005, Pages 353-363
The role of high frequencies in speech localization.
Best V, Carlile S, Jin C, van Schaik A
This study measured the accuracy with which human listeners can localize spoken words. A broadband (300 Hz-16 kHz) corpus of monosyllabic words was created and presented tolisteners using a virtual auditory environment. Localization was examined for 76 locations ona sphere surrounding the listener. Experiment 1 showed that low-pass filtering the speech sounds at 8 kHz degraded performance, causing an increase in polar angle errors associated with the cone of confusion. In experiment 2 it was fou...
Abstract
Cited 1 times since 2005 (0 per year)
source: EuropePMC
Haemophilia : the official journal of the World Federation of Hemophilia,
Volume 11, Issue 4, 1 1 2005, Pages 366-370
The effect of clotting factor concentrates on the immune system in HIV-negative haemophilics.
Balkan C, Kavakli K, Kutukculer N, Aksu G, Yilmaz D, Aydinok Y
Immune abnormalities have been reported in patients with haemophilia. Although infections with HIV and hepatitis viruses contribute to these abnormalities, chronic exposure to extraneous proteins in clotting factor concentrates (CFC) may also play a role. A number of studies suggest that the degree of immunological abnormalities correlates with the amount of intermediate purity CFC administered over time. The purpose of this study was to investigate whether there were cellular and humoral immuno...
Abstract
Cited 30 times since 2005 (1.5 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 46, Issue 1, 1 1 2005, Pages 15-20
Sustained benefit 20 years after reperfusion therapy in acute myocardial infarction.
van Domburg RT, Sonnenschein K, Nieuwlaat R, Kamp O, Storm CJ, Bax JJ, Simoons ML
Objectives: The goal of this research was to clarify whether the benefit of reperfusion therapy for myocardial infarction was sustained long-term and to assess the gain in life expectancy by reperfusion therapy. Background: Reperfusion therapy in acute myocardial infarction reduces infarct size and increases hospital survival. Methods: We analyzed the 20-year outcome of 533 patients (mean age 56 years; 82% men) who were randomized to either reperfusion therapy or conventional therapy during the...
Abstract
Cited 8 times since 2005 (0.4 per year)
source: EuropePMC
Journal of hypertension,
Volume 23, Issue 7, 1 1 2005, Pages 1409-1415
Simultaneous echocardiography and myocardial perfusion single photon emission computed tomography associated with dobutamine stress to predict long-term cardiac mortality in normotensive and hypertensive patients.
Bigi R, Bax JJ, van Domburg RT, Elhendy A, Cortigiani L, Schinkel AF, Fiorentini C, Poldermans D
Background: Echocardiography and myocardial scintigraphy associated with dobutamine stress are used for assessing risk in coronary artery disease. We compared the accuracy of the two modalities applied simultaneously for predicting long-term cardiac mortality in normotensive and hypertensive patients. Methods: Three hundred and fifty-one consecutive patients underwent dobutamine stress with simultaneous echocardiography and Tc-sestamibi single photon emission computed tomography (SPECT). Fifty p...
Abstract
Cited 1 times since 2005 (0 per year)
source: EuropePMC
European journal of nuclear medicine and molecular imaging,
Volume 32, Issue 7, 1 1 2005, Pages 829-831
FDG imaging should be considered the preferred technique for accurate assessment of myocardial viability: for.
Bax JJ
Abstract
Cited 28 times since 2005 (1.4 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 16, Issue 7, 1 1 2005, Pages 701-707
Long-term follow-up of cardiac resynchronization therapy in patients with end-stage heart failure.
Molhoek SG, Bax JJ, Bleeker GB, Holman ER, Van Erven L, Bootsma M, Boersma E, Steendijk P, Van Der Wall EE, Schalij MJ
Unlabelled: Long-term follow-up of cardiac resynchronization therapy. Introduction: Cardiac resynchronization therapy (CRT) has been introduced to treat patients with end-stage heart failure, and results of this technique are promising. The aim of our study was to assess the sustained benefit of CRT in a large patient cohort with end-stage heart failure at long-term follow-up. In addition, the prognosis of responders and nonresponders was evaluated. Methods and results: 125 patients with end-sta...
Abstract
Cited 19 times since 2005 (0.9 per year)
source: EuropePMC
Ophthalmology,
Volume 112, Issue 7, 1 1 2005, Pages 1310-1315
Coronal or swinging eyelid decompression for patients with disfiguring proptosis in Graves' orbitopathy? Comparison of results in one center.
Sasim IV, de Graaf ME, Berendschot TT, Kalmann R, van Isterdael C, Mourits MP
Purpose: To compare 2 different approaches for 3-wall orbital decompression in patients with disfiguring proptosis due to Graves' orbitopathy, and to determine which technique is preferable. Design: Retrospective nonrandomized study with a concurrent comparison group. Participants: Charts of 74 consecutive patients with disfiguring proptosis due to Graves' orbitopathy who underwent coronal (46) or swinging eyelid (28) decompression between January 1, 2000 and January 1, 2004 were studi...
Abstract
Future cardiology,
Volume 1, Issue 4, 1 1 2005, Pages 479-488
The role of insulin-like growth factor during a postischemic period - new insights into pathophysiologic pathways in cardiac tissue.
Palmen M, Twickler MT, Daemen MJ, Cramer MJ, Doevendans PA
Despite an improvement in the therapeutic strategies available for an acute ischemic event, cardiac disease is still the principal cause of morbidity and mortality in Western societies. A shift from acute towards more chronic heart disease due to atherosclerotic disease has been recognized. Modification of adaptive capacities of the cardiac muscle after damage remains a key component in the prevention of chronic cardiac disease, such as overt heart failure. It has recently been demonstrated that...
Abstract
Cited 29 times since 2005 (1.4 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 91, Issue 7, 1 1 2005, Pages 981-990
Clinical applications of intracardiac echocardiography in interventional procedures.
Jongbloed MR, Schalij MJ, Zeppenfeld K, Oemrawsingh PV, van der Wall EE, Bax JJ
Abstract
Cited 18 times since 2005 (0.9 per year)
source: EuropePMC
The American journal of cardiology,
Volume 96, Issue 1, 1 1 2005, Pages 108-111
Comparison of effectiveness of cardiac resynchronization therapy in patients with versus without diabetes mellitus.
Kiès P, Bax JJ, Molhoek SG, Bleeker GB, Boersma E, Steendijk P, van der Wall EE, Schalij MJ
The effect of long-term cardiac resynchronization therapy (CRT) was evaluated in 32 patients with heart failure (HF) and diabetes mellitus (DM) compared with 65 patients with HF and no DM. Clinical parameters were obtained before and after 6 months of CRT. Long-term follow-up was performed
Abstract
Cited 38 times since 2005 (1.9 per year)
source: EuropePMC
The Journal of clinical endocrinology and metabolism,
Volume 90, Issue 9, 28 4 2005, Pages 5313-5316
A common polymorphism in the CYP3A7 gene is associated with a nearly 50% reduction in serum dehydroepiandrosterone sulfate levels.
Smit P, van Schaik RH, van der Werf M, van den Beld AW, Koper JW, Lindemans J, Pols HA, Brinkmann AO, de Jong FH, Lamberts SW
Context: CYP3A7, expressed in the human fetal liver and normally silenced after birth, plays a major role in the 16alpha-hydroxylation of dehydroepiandrosterone (DHEA), DHEA sulfate (DHEAS), and estrone. Due to a replacement of part of the CYP3A7 promoter with a sequence identical with the same region in the CYP3A4 promoter (referred to as CYP3A7*1C), some individuals still express a variant of the CYP3A7 gene later in life. Objective: The objective of this study was to examine the effect of the...
Abstract
Cited 28 times since 2005 (1.4 per year)
source: EuropePMC
Primates; journal of primatology,
Volume 46, Issue 4, 28 4 2005, Pages 249-254
A simple alternative to line transects of nests for estimating orangutan densities.
van Schaik CP, Wich SA, Utami SS, Odom K
We conducted a validation of the line transect technique to estimate densities of orangutan (Pongo pygmaeus) nests in a Bornean swamp forest, and compared these results with density estimates based on nest counts in plots and on female home ranges. First, we examined the accuracy of the line transect method. We found that the densities based on a pass in both directions of two experienced pairs of observers was 27% below a combined sample based on transect walks by eight pairs of observers, sugg...
Abstract
