9618 results
Cited 18 times since 2005 (0.9 per year)
source: EuropePMC
European journal of human genetics : EJHG,
Volume 13, Issue 4, 1 1 2005, Pages 445-451
Polymorphisms in APOA1 and LPL genes are statistically independently associated with fasting TG in men with CAD.
Souverein OW, Jukema JW, Boekholdt SM, Zwinderman AH, Tanck MW
The objective of this paper was to identify the single nucleotide polymorphisms (SNPs) that show unshared effects on plasma triglyceride (TG) levels and to investigate whether these SNPs show statistically independent effects on plasma TG levels. In total, 59 polymorphisms in 20 genes involved in lipid metabolism were investigated. Polymorphisms were selected for a multivariate ANOVA model if they showed an univariate association with TG (after adjustment for HDL-C and LDL-C) in more than 50% of...
Abstract
Cited 90 times since 2005 (4.4 per year)
source: EuropePMC
Leukemia,
Volume 19, Issue 4, 1 1 2005, Pages 537-544
Causes of death--other than progressive leukemia--in childhood acute lymphoblastic (ALL) and myeloid leukemia (AML): the Dutch Childhood Oncology Group experience.
Slats AM, Egeler RM, van der Does-van den Berg A, Korbijn C, Hählen K, Kamps WA, Veerman AJ, Zwaan CM
We analyzed causes of death, other than resistant disease or relapse, in 875 children with acute lymphoblastic leukemia (ALL) and 229 with acute myeloid leukemia (AML), treated on three different Dutch Childhood Oncology Group (DCOG) ALL and three AML protocols. Overall, 23 (2.6%) ALL and 44 (19.2%) AML patients died. Early death (ED, before remission was reached) occurred in nine ALL (1%) and thirty AML (13.1%) patients, including three and ten deaths before treatment was initiated. Chemotherap...
Abstract
Clinical pediatrics,
Volume 44, Issue 3, 1 1 2005, Pages 259-261
Subacute sclerosing panencephalitis in a patient with cerebral palsy.
Yilmaz D, Senbil N, Aydin OF, Yüksel D
Abstract
Cited 36 times since 2005 (1.8 per year)
source: EuropePMC
Annals of neurology,
Volume 57, Issue 4, 1 1 2005, Pages 589-591
Early onset neuropathy in a compound form of Charcot-Marie-Tooth disease.
Meggouh F, de Visser M, Arts WF, De Coo RI, van Schaik IN, Baas F
A 2-year-old boy presented with early-onset Charcot-Marie-Tooth disease (CMT). His parents had not been diagnosed previously with CMT, but on careful examination they showed clinical signs of CMT and reduced nerve conduction velocities. Genetic analysis identified the boy as a heterozygote for both a peripheral myelin protein 22 (PMP22) duplication and a mutation in the lipopolysaccharide-induced-tumour-necrosis-factor-alpha-factor (LITAF) gene, whereas each parent only had one mutated CMT gene....
Abstract
Cited 31 times since 2005 (1.5 per year)
source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 27, Issue 4, 1 1 2005, Pages 544-547
Intraoperative stenting of pulmonary arteries.
Bökenkamp R, Blom NA, De Wolf D, Francois K, Ottenkamp J, Hazekamp MG
Objective: The surgical treatment of pulmonary artery stenoses in small children with complex cardiac lesions can be technically difficult. A hybrid-approach combining corrective surgery and intraoperative stent placement may be complementary in these patients. Methods: Descriptive study in 11 small children (age: one week to 12 years, median of 12 months, weight: 2.5-20 kg) after previous cardiac surgery. Intraoperative stenting of pulmonary arteries was performed involving paediatric cardiolog...
Abstract
Cited 103 times since 2005 (5.1 per year)
source: EuropePMC
Current opinion in biotechnology,
Volume 16, Issue 2, 1 1 2005, Pages 218-224
The role of sigmaB in the stress response of Gram-positive bacteria -- targets for food preservation and safety.
van Schaik W, Abee T
The alternative sigma factor sigmaB modulates the stress response of several Gram-positive bacteria, including Bacillus subtilis and the food-borne human pathogens Bacillus cereus, Listeria monocytogenes and Staphylococcus aureus. In all these bacteria, sigmaB is responsible for the transcription of genes that can confer stress resistance to the vegetative cell. Recent findings indicate that sigmaB also plays an important role in antibiotic resistance, pathogenesis and cellular differentiation p...
Abstract
Cited 3 times since 2005 (0.1 per year)
source: EuropePMC
Annals of internal medicine,
Volume 142, Issue 8, 1 1 2005, Pages 678; author reply 678-9
Transient left ventricular apical ballooning.
Alizadeh Dehnavi R, van der Wall EE
Abstract
Cited 102 times since 2005 (5 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 45, Issue 7, 1 1 2005, Pages 1109-1116
Feasibility of tissue magnetic resonance imaging: a pilot study in comparison with tissue Doppler imaging and invasive measurement.
Paelinck BP, de Roos A, Bax JJ, Bosmans JM, van Der Geest RJ, Dhondt D, Parizel PM, Vrints CJ, Lamb HJ
Objectives: This research was intended to determine the feasibility of tissue magnetic resonance (MR) imaging in comparison with tissue Doppler imaging and its potential implications for the estimation of filling pressure, in comparison with invasive measurement. Background: Evaluation of diastolic function using MR imaging is commonly confined to the study of transmitral flow. However, transmitral flow is unreliable for the estimation of left ventricular (LV) filling pressures in hypertrophy an...
Abstract
Cited 5 times since 2005 (0.2 per year)
source: EuropePMC
The international journal of cardiovascular imaging,
Volume 21, Issue 2-3, 1 1 2005, Pages 343-345
Non-invasive visualization of the coronary arteries with multi-detector row computed tomography; influence of technical advances on clinical applicability.
Schuijf JD, Bax JJ, van der Wall EE
Abstract
Cited 68 times since 2005 (3.3 per year)
source: EuropePMC
The Journal of urology,
Volume 173, Issue 4, 1 1 2005, Pages 1375-1380
Effect of hyperthermia on the cytotoxicity of 4 chemotherapeutic agents currently used for the treatment of transitional cell carcinoma of the bladder: an in vitro study.
van der Heijden AG, Verhaegh G, Jansen CF, Schalken JA, Witjes JA
Purpose: Hyperthermia combined with chemotherapy is not a novel cancer treatment. However, the working mechanism of this combination therapy is not fully understood. In the current in vitro study we investigated the differences in cytotoxicity of 4 chemotherapeutic agents at 37C or 43C. Materials and methods: The human transitional cell carcinoma cell lines used were RT4, RT112, 253J and T24. Cells were seeded in 96-well microtiter plates. After 24 hours cells were treated for 60 minutes with in...
Abstract
Cited 45 times since 2005 (2.2 per year)
source: EuropePMC
The American journal of cardiology,
Volume 95, Issue 8, 1 1 2005, Pages 925-929
Which parameters on magnetic resonance imaging determine Q waves on the electrocardiogram?
Kaandorp TA, Bax JJ, Lamb HJ, Viergever EP, Boersma E, Poldermans D, van der Wall EE, de Roos A
Studies have demonstrated that patients with Q-wave infarctions on the electrocardiogram (ECG) frequently have nontransmural scar formation, whereas non-Q-wave infarctions may have transmural scars. The precise pathophysiologic substrate that underlies Q waves remains unclear. Magnetic resonance imaging (MRI) is the preferred technique to evaluate patients who have infarction because information can be obtained on function, contractile reserve (viability), and scar tissue. Consecutive patients (...
Abstract
Cited 43 times since 2005 (2.1 per year)
source: EuropePMC
Pacing and clinical electrophysiology : PACE,
Volume 28, Issue 4, 1 1 2005, Pages 304-310
Cardiac resynchronization induces favorable neurohumoral changes.
Erol-Yilmaz A, Verberne HJ, Schrama TA, Hrudova J, De Winter RJ, Van Eck-Smit BL, De Bruin R, Bax JJ, Schalij MJ, Wilde AA, Tukkie R
Aim: The aim of this article is to examine whether cardiac resynchronization therapy (CRT) induces improvements in the neurohumoral system. Methods and results: Thirteen patients with HF (left ventricular (LV) ejection fraction
Abstract
Cited 3 times since 2005 (0.1 per year)
source: EuropePMC
European heart journal,
Volume 26, Issue 11, 24 4 2005, Pages 1054-1055
How to predict response to cardiac resynchronization therapy?
Bax JJ, Schalij MJ
Abstract
Cited 81 times since 2005 (4 per year)
source: EuropePMC
The EMBO journal,
Volume 24, Issue 7, 17 3 2005, Pages 1406-1417
Cell cycle regulation of chromatin at an origin of DNA replication.
Zhou J, Chau CM, Deng Z, Shiekhattar R, Spindler MP, Schepers A, Lieberman PM
Selection and licensing of mammalian DNA replication origins may be regulated by epigenetic changes in chromatin structure. The Epstein-Barr virus (EBV) origin of plasmid replication (OriP) uses the cellular licensing machinery to regulate replication during latent infection of human cells. We found that the minimal replicator sequence of OriP, referred to as the dyad symmetry (DS), is flanked by nucleosomes. These nucleosomes were subject to cell cycle-dependent chromatin remodeling and histone...
Abstract
Cited 30 times since 2005 (1.5 per year)
source: EuropePMC
Circulation research,
Volume 96, Issue 7, 10 2 2005, Pages 776-783
Development of the right ventricular inflow tract and moderator band: a possible morphological and functional explanation for Mahaim tachycardia.
Jongbloed MR, Wijffels MC, Schalij MJ, Blom NA, Poelmann RE, van der Laarse A, Mentink MM, Wang Z, Fishman GI, Gittenberger-de Groot AC
Atriofascicular accessory bundles with AV-node like conduction properties can sustain atrioventricular (AV) re-entrant tachycardia (Mahaim tachycardia). During early embryogenesis, the AV canal is situated above the primitive left ventricle (LV), and a right AV connection has not been achieved yet. We studied the formation of the right ventricular (RV) inflow tract in relation to the developing cardiac conduction system and hypothesized a morphological explanation for functional atriofascicular...
Abstract
Cited 6 times since 2005 (0.3 per year)
source: EuropePMC
European heart journal,
Volume 26, Issue 9, 10 2 2005, Pages 941
Aortic arch morphology and hypertension in post-coarctectomy patients.
Vriend JW, Oosterhof T, Hazekamp MG, Mulder BJ
Abstract
Cited 18 times since 2005 (0.9 per year)
source: EuropePMC
British journal of cancer,
Volume 92, Issue 5, 1 1 2005, Pages 882-887
Adenoviral vector-mediated expression of a gene encoding secreted, EpCAM-targeted carboxylesterase-2 sensitises colon cancer spheroids to CPT-11.
Oosterhoff D, Overmeer RM, de Graaf M, van der Meulen IH, Giaccone G, van Beusechem VW, Haisma HJ, Pinedo HM, Gerritsen WR
CPT-11 (irinotecan or 7-ethyl-10[4-(1-piperidino)-1-piperidino] carbonyloxycamptothecin) is an anticancer agent in use for the treatment of colon cancer. In order to be fully active, CPT-11 needs to be converted into SN-38 (7-ethyl-10-hydroxycamptothecin) by the enzyme carboxylesterase (CE). In humans, only a minority of CPT-11 is converted to SN-38. To increase the antitumour effect of CPT-11 by gene-directed enzyme prodrug therapy, we constructed a replication-deficient adenoviral vector Ad.C2...
Abstract
Cited 5 times since 2005 (0.2 per year)
source: EuropePMC
Nederlands tijdschrift voor geneeskunde,
Volume 149, Issue 11, 1 1 2005, Pages 589-593
[Complete atrioventricular septal defect in children with Down's syndrome: good results of surgical correction at younger and younger ages].
Kortenhorst MS, Hazekamp MG, Rammeloo LA, Schoof PH, Ottenkamp J
Objective: To evaluate the results of cardiosurgical treatment of children with Down's syndrome and a complete atrioventricular septal defect (cAVSD). Design: Retrospective. Method: Data were collected from the records of all patients with Down's syndrome who had been subjected to primary corrective surgery for cAVSD in the period 1980-2003 in Leiden, The Netherlands. Exclusion criteria were: concomitant tetralogy of Fallot or interruption of the aortic arch and palliative banding of t...
Abstract
Cited 45 times since 2005 (2.2 per year)
source: EuropePMC
Journal of vascular surgery,
Volume 41, Issue 3, 1 1 2005, Pages 443-450
Assessment of disease impact in patients with intermittent claudication: discrepancy between health status and quality of life.
Breek JC, de Vries J, van Heck GL, van Berge Henegouwen DP, Hamming JF
Objective: To describe similarities and differences between health status and quality of life in patients with intermittent claudication. Methods: This was an observational study in the vascular outpatient department of a teaching hospital; it concerned 200 consecutive patients with intermittent claudication. Health status was assessed with the RAND-36, and quality of life was assessed with a reduced version of the World Health Organization Quality of Life assessment instrument-100. Scores were...
Abstract
Cited 76 times since 2005 (3.7 per year)
source: EuropePMC
The American journal of cardiology,
Volume 95, Issue 5, 1 1 2005, Pages 571-574
Noninvasive coronary imaging and assessment of left ventricular function using 16-slice computed tomography.
Schuijf JD, Bax JJ, Salm LP, Jukema JW, Lamb HJ, van der Wall EE, de Roos A
In recent years, multislice computed tomography (MSCT) has been demonstrated to be a feasible imaging modality for noninvasive coronary angiography and left ventricular function analysis. The present study evaluated overall performance of 16-slice MSCT in the detection of significant coronary artery disease, stent, or bypass graft stenosis in combination with global left ventricular function analysis. Forty-five patients underwent 16-slice MSCT. Multislice computed tomograms were used to evaluat...
Abstract
