8821 results
Cited 27 times since 2020 (6 per year)
source: EuropePMC
Cancers,
Volume 12, Issue 9, 21 3 2020, Pages E2692
Prognostic and Predictive Value of Tumor-Infiltrating Immune Cells in Urothelial Cancer of the Bladder.
van Wilpe S, Gerretsen ECF, van der Heijden AG, de Vries IJM, Gerritsen WR, Mehra N
The prognosis and responsiveness to chemotherapy and checkpoint inhibitors differs substantially among patients with bladder cancer (BC). There is an unmet need for biomarkers that can accurately predict prognosis and treatment outcome. Here, we describe the available literature on the prognostic and predictive value of tumor-infiltrating immune cells in BC. Current evidence indicates that a high density of tumor-infiltrating CD8+ T cells is a favorable prognostic factor, whereas PD-L1 expressio...
Abstract
European journal of applied physiology,
Volume 120, Issue 12, 20 3 2020, Pages 2761-2772
Two isothermal challenges yield comparable physiological and subjective responses.
Klous L, Psikuta A, Gijsbertse K, Mol D, van Schaik M, Daanen HAM, Kingma BRM
Purpose: Ventilated vests are developed to reduce thermal stress by enhancing convective and evaporative cooling from skin tissue underneath the vest. The purpose of this study is to investigate whether thermal stress is equal when a ventilated vest is worn compared to a no-vest situation with similar dry thermal resistance. Methods: Nine healthy males walked on a treadmill (7 km h-1) for 45 min in a desert climate (34 °C, 20% relative humidity) with and without ventilated vest. Gastrointestinal...
Abstract
Cited 3 times since 2020 (0.7 per year)
source: EuropePMC
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland,
Volume 22, Issue 12, 18 3 2020, Pages 2288-2297
Timing of nasogastric tube insertion and the risk of postoperative pneumonia: an international, prospective cohort study.
EuroSurg Collaborative
Aim: Aspiration is a common cause of pneumonia in patients with postoperative ileus. Insertion of a nasogastric tube (NGT) is often performed, but this can be distressing. The aim of this study was to determine whether the timing of NGT insertion after surgery (before versus after vomiting) was associated with reduced rates of pneumonia in patients undergoing elective colorectal surgery. Method: This was a preplanned secondary analysis of a multicentre, prospective cohort study. Patients undergo...
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
International journal of nursing education scholarship,
Volume 17, Issue 1, 18 3 2020, Pages /j/ijnes.2020.17.issue-1/ijnes-2020-0011/ijnes-202
The effectiveness of scenario-based learning to develop patient safety behavior in first year nursing students.
Yilmaz DU, Palandoken EA, Ceylan B, Akbiyik A
The aim of this study was to examine the effect of scenario-based learning (SBL) compared to traditional demonstration method on the development of patient safety behavior in first year nursing students. During the 2016-2017 academic year, the Fundamentals of Nursing course curriculum contained the teaching of demonstration method (n=168). In the academic year 2017-2018 was performed with SBL method in the same context (n=183). Objective Structured Clinical Examination (OSCE) that assesses the s...
Abstract
Clinical chemistry and laboratory medicine,
Volume 59, Issue 1, 18 3 2020, Pages e13-e17
Successfully meeting analytical expectations for the fast 0/1-h algorithm for NSTEMI by internal control procedures for cardiac troponin T.
Endlich W, Mensink WJ, den Elzen WPJ, Tops LF, Cobbaert CM
Abstract
Cited 3 times since 2020 (0.7 per year)
source: EuropePMC
Infection and immunity,
Volume 88, Issue 10, 18 3 2020, Pages e00204-20
Intratracheal Inoculation with Brucella melitensis in the Pregnant Guinea Pig Is an Improved Model for Reproductive Pathogenesis and Vaccine Studies.
Hensel ME, Chaki SP, Stranahan L, Gregory AE, van Schaik EJ, Garcia-Gonzalez DG, Khalaf O, Samuel JE, Arenas-Gamboa AM
Reproductive failure is the hallmark of brucellosis in animals. An uncommon but important complication in pregnant women who become acutely infected with Brucella melitensis is spontaneous pregnancy loss or vertical transmission to the fetus. Unfortunately, the mechanism behind reproductive failure is still obscure, partially due to the lack of a proper study model. Recently, it was demonstrated that intratracheal (IT) inoculation of nonpregnant guinea pigs would replicate features of clinical d...
Abstract
Cited 8 times since 2020 (1.8 per year)
source: EuropePMC
The Journal of arthroplasty,
Volume 36, Issue 3, 18 3 2020, Pages 863-878
Rates and Causes of 90-day Complications and Readmissions Following Outpatient Hip and Knee Arthroplasty: A Retrospective Analysis of 525 Patients in a Single Institution.
Keulen MHF, Schotanus MGM, van Haaren EH, van Hemert WLW, Heyligers IC, Boonen B
Background: Outpatient joint arthroplasty (OJA) has gained increasing popularity and success in a well-defined population. Safety concerns, in terms of complications and readmissions, however still exist. Patients and methods: This retrospective study included 525 patients (90 primary THAs, 277 primary TKAs, and 158 primary UKAs), initially planned for OJA. All complications and readmissions were evaluated for timing and cause (surgical vs medical) within a 90-day followup. Complications and rea...
Abstract
Cited 13 times since 2020 (2.9 per year)
source: EuropePMC
Biological reviews of the Cambridge Philosophical Society,
Volume 96, Issue 1, 16 3 2020, Pages 66-88
Reproductive seasonality in primates: patterns, concepts and unsolved questions.
Heldstab SA, van Schaik CP, Müller DWH, Rensch E, Lackey LB, Zerbe P, Hatt JM, Clauss M, Matsuda I
Primates, like other mammals, exhibit an annual reproductive pattern that ranges from strictly seasonal breeding to giving birth in all months of the year, but factors mediating this variation are not fully understood. We applied both a categorical description and quantitative measures of the birth peak breadth based on daily observations in zoos to characterise reproductive seasonality in 141 primate species with an average of 941 birth events per species. Absolute day length at the beginning o...
Abstract
Cited 7 times since 2020 (1.6 per year)
source: EuropePMC
The American journal of cardiology,
Volume 136, 15 3 2020, Pages 131-139
Prognostic Implications of Increased Right Ventricular Wall Tension in Secondary Tricuspid Regurgitation.
Fortuni F, Dietz MF, Butcher SC, Prihadi EA, van der Bijl P, Ajmone Marsan N, Delgado V, Bax JJ
Secondary tricuspid regurgitation (TR) imposes a chronic volume overload on the right ventricle (RV) which can increase RV wall tension (RVWT). The aim of this study was to investigate the prognostic implications of increased RVWT in patients with significant secondary TR. A total of 1,142 patients with moderate-to-severe secondary TR were included. Based on the simplified Laplace-Young's law, RVWT was defined as the product between pulmonary artery systolic pressure (PASP) and RV base-to-a...
Abstract
Cited 29 times since 2020 (6.5 per year)
source: EuropePMC
Frontiers in pharmacology,
Volume 11, 11 2 2020, Pages 575540
Pharmacogenetics in Psychiatry: An Update on Clinical Usability.
van Schaik RHN, Müller DJ, Serretti A, Ingelman-Sundberg M
Using pharmacogenetics in guiding drug therapy experiences a steady increase in uptake, although still leads to discussions as to its clinical use. Psychiatry constitutes a field where pharmacogenomic testing might help in guiding drug therapy. To address current challenges, this minireview provides an update regarding genotyping (SNP analysis/arrays/NGS), structural variant detection (star-alleles/CNVs/hybrid alleles), genotype-to-phenotype translations, cost-effectiveness, and actionability of...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 34, Issue 1, 10 2 2020, Pages 20-29
The Obesity Paradox in Patients with Significant Tricuspid Regurgitation: Effects of Obesity on Right Ventricular Remodeling and Long-Term Prognosis.
Dietz MF, Prihadi EA, van der Bijl P, Ajmone Marsan N, Bax JJ, Delgado V
Background: Obesity may cause right ventricular (RV) remodeling due to volume overload. However, obesity is also associated with better prognosis compared with normal weight in patients with various cardiac diseases. The aim of this study was to assess the impact of obesity on RV remodeling and long-term prognosis in patients with significant (moderate and severe) tricuspid regurgitation (TR). Methods: A total of 951 patients with significant TR (median age, 70 years; interquartile range, 61-77 ...
Abstract
Cited 36 times since 2020 (8 per year)
source: EuropePMC
Neurology,
Volume 95, Issue 24, 10 2 2020, Pages e3331-e3343
Association of common genetic variants with brain microbleeds: A genome-wide association study.
Knol MJ, Lu D, Traylor M, Adams HHH, Romero JRJ, Smith AV, Fornage M, Hofer E, Liu J, Hostettler IC, Luciano M, Trompet S, Giese AK, Hilal S, van den Akker EB, Vojinovic D, Li S, Sigurdsson S, van der Lee SJ, Jack CR, Wilson D, Yilmaz P, Satizabal CL, Liewald DCM, van der Grond J, Chen C, Saba Y, van der Lugt A, Bastin ME, Windham BG, Cheng CY, Pirpamer L, Kantarci K, Himali JJ, Yang Q, Morris Z, Beiser AS, Tozer DJ, Vernooij MW, Amin N, Beekman M, Koh JY, Stott DJ, Houlden H, Schmidt R, Gottesman RF, MacKinnon AD, DeCarli C, Gudnason V, Deary IJ, van Duijn CM, Slagboom PE, Wong TY, Rost NS, Jukema JW, Mosley TH, Werring DJ, Schmidt H, Wardlaw JM, Ikram MA, Seshadri S, Launer LJ, Markus HS, Alzheimer's Disease Neuroimaging Initiative
Objective: To identify common genetic variants associated with the presence of brain microbleeds (BMBs). Methods: We performed genome-wide association studies in 11 population-based cohort studies and 3 case-control or case-only stroke cohorts. Genotypes were imputed to the Haplotype Reference Consortium or 1000 Genomes reference panel. BMBs were rated on susceptibility-weighted or T2*-weighted gradient echo MRI sequences, and further classified as lobar or mixed (including strictly deep and inf...
Abstract
Cited 4 times since 2020 (0.9 per year)
source: EuropePMC
Medical education,
Volume 54, Issue 11, 10 2 2020, Pages 972-974
Medical trainees as job crafters: Looking at identity formation through another lens.
Bochatay N, van Schaik S, O'Brien B
Abstract
Pediatrics international : official journal of the Japan Pediatric Society,
Volume 62, Issue 9, 9 2 2020, Pages 1094-1100
Efficacy of Buzzy<sup>®</sup> on pain and anxiety during catheterization in children.
Yılmaz D, Özyazıcıoğlu N, Çıtak Tunç G, Aydın Aİ, Atak M, Duygulu Ş, Demirtaş Z
Background: The use of a peripheral intravenous cannula is a common clinical practice, and it is known to be a major source of pain and anxiety in children. The aim of this study was to examine the effect of the use of the Buzzy® on pain and anxiety in children during peripheral cannula application. Methods: The research sample consisted of 60 children between the ages of 8 and 16. For children in the experimental group, external cold and vibration were applied by means of the Buzzy® device. Bef...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Radiology case reports,
Volume 15, Issue 11, 7 1 2020, Pages 2205-2207
Antegrade common femoral artery access site closure using the MANTA vascular closure device.
Stomp W, Eefting D, van Schaik J, Sudiono DR, van der Meer RW
In antegrade peripheral endovascular procedures, the use of covered stents may require a large sheath size, which precludes the use of regular closure devices. The MANTA vascular closure device is a collagen plug-based vascular closure device for large bore percutaneous arterial interventions, which is normally used to close retrograde vascular access sites. We describe successful antegrade common femoral access site closure with the MANTA vascular closure device in 2 patients, a 68-year-old mal...
Abstract
Cited 6 times since 2020 (1.3 per year)
source: EuropePMC
Philosophical transactions of the Royal Society of London. Series B, Biological sciences,
Volume 375, Issue 1810, 7 1 2020, Pages 20190509
Spring enhancement and summer reduction in carbon uptake during the 2018 drought in northwestern Europe.
Smith NE, Kooijmans LMJ, Koren G, van Schaik E, van der Woude AM, Wanders N, Ramonet M, Xueref-Remy I, Siebicke L, Manca G, Brümmer C, Baker IT, Haynes KD, Luijkx IT, Peters W
We analysed gross primary productivity (GPP), total ecosystem respiration (TER) and the resulting net ecosystem exchange (NEE) of carbon dioxide (CO2) by the terrestrial biosphere during the summer of 2018 through observed changes across the Integrated Carbon Observation System (ICOS) network, through biosphere and inverse modelling, and through remote sensing. Highly correlated yet independently-derived reductions in productivity from sun-induced fluorescence, vegetative near-infrared reflectan...
Abstract
Cited 7 times since 2020 (1.6 per year)
source: EuropePMC
Philosophical transactions of the Royal Society of London. Series B, Biological sciences,
Volume 375, Issue 1810, 7 1 2020, Pages 20190512
Changes in net ecosystem exchange over Europe during the 2018 drought based on atmospheric observations.
Thompson RL, Broquet G, Gerbig C, Koch T, Lang M, Monteil G, Munassar S, Nickless A, Scholze M, Ramonet M, Karstens U, van Schaik E, Wu Z, Rödenbeck C
The 2018 drought was one of the worst European droughts of the twenty-first century in terms of its severity, extent and duration. The effects of the drought could be seen in a reduction in harvest yields in parts of Europe, as well as an unprecedented browning of vegetation in summer. Here, we quantify the effect of the drought on net ecosystem exchange (NEE) using five independent regional atmospheric inversion frameworks. Using a network of atmospheric CO2 mole fraction observations, we estim...
Abstract
Cited 53 times since 2020 (11.8 per year)
source: EuropePMC
EMBO reports,
Volume 21, Issue 11, 7 1 2020, Pages e50636
Cell cycle dynamics of lamina-associated DNA.
van Schaik T, Vos M, Peric-Hupkes D, Hn Celie P, van Steensel B
In mammalian interphase nuclei, more than one thousand large genomic regions are positioned at the nuclear lamina (NL). These lamina-associated domains (LADs) are involved in gene regulation and may provide a backbone for the folding of interphase chromosomes. Little is known about the dynamics of LADs during interphase, in particular at the onset of G1 phase and during DNA replication. We developed an antibody-based variant of the DamID technology (named pA-DamID) that allows us to map and visu...
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
Annals of vascular surgery,
Volume 71, 3 1 2020, Pages 411-418
Stent Graft Sizing for Endovascular Abdominal Aneurysm Repair Using Open Source Image Processing Software.
Knöps E, van Schaik J, van der Bogt KEA, Veger HTC, Putter H, Waasdorp EJ, van der Vorst JR
Introduction: An important step to reach a favorable outcome of abdominal endovascular aneurysm repair (EVAR) is preoperative sizing of the stent graft using computed tomography angiography (CTA) images of the abdominal aorta. A variety of costly image processing software options is available to obtain the necessary aortic measurements. A package that can be used for EVAR sizing is OsiriX Lite®-an open source, freely downloadable image processing option. This study assesses the concurrent validi...
Abstract
Cited 44 times since 2020 (9.7 per year)
source: EuropePMC
Journal of medical Internet research,
Volume 22, Issue 9, 2 1 2020, Pages e20953
Telemonitoring for Patients With COVID-19: Recommendations for Design and Implementation.
Silven AV, Petrus AHJ, Villalobos-Quesada M, Dirikgil E, Oerlemans CR, Landstra CP, Boosman H, van Os HJA, Blanker MH, Treskes RW, Bonten TN, Chavannes NH, Atsma DE, Teng YKO
Despite significant efforts, the COVID-19 pandemic has put enormous pressure on health care systems around the world, threatening the quality of patient care. Telemonitoring offers the opportunity to carefully monitor patients with a confirmed or suspected case of COVID-19 from home and allows for the timely identification of worsening symptoms. Additionally, it may decrease the number of hospital visits and admissions, thereby reducing the use of scarce resources, optimizing health care capacit...
Abstract
