Research

Publications

Below you can find a list of our published research.

8684 results

Cited 26 times since 2013 (2.3 per year) source: Scopus

International journal of behavioral medicine, Volume 20, Issue 4, 1 1 2013, Pages 582-589 Changes in illness perceptions and quality of life during participation in cardiac rehabilitation. Janssen V, De Gucht V, van Exel H, Maes S

Background: The beliefs patients hold about their disease and corresponding treatment have been shown to predict recovery in cardiac patients. Purpose: However, it is not known to what extent these beliefs change during participation in cardiac rehabilitation and whether this is related to psychological indicators of outcome. Method: Illness perceptions and health-related quality of life (HRQOL) were measured upon entry to (T0) and completion of (T1) a 3-month outpatient cardiac rehabilitation p... Abstract

Cited 12 times since 2013 (1 per year) source: EuropePMC

Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 21, Issue 12, 1 1 2013, Pages 540-544 What do cardiologists know about the effects of cardiovascular agents on sexual function? A survey among Dutch cardiologists. Part I. Nicolai MP, Liem SS, Both S, Pelger RC, Putter H, Schalij MJ, Elzevier HW

Introduction: Several cardiovascular agents, such as diuretics and β-blockers, can negatively affect sexual function, leading to noncompliance with therapy. Others such as angiotensin II receptor blockers (ARBs) can improve patients' sexual function. Aims: We aimed to gain insight into cardiologists' knowledge about the effects of cardiovascular drugs on sexual function and whether they take this knowledge into account when prescribing drugs. Methods: An anonymous questionnaire was mai... Abstract

Cited 21 times since 2013 (1.8 per year) source: EuropePMC

Pharmacogenetics and genomics, Volume 23, Issue 12, 1 1 2013, Pages 649-657 Single-nucleotide polymorphisms in P450 oxidoreductase and peroxisome proliferator-activated receptor-α are associated with the development of new-onset diabetes after transplantation in kidney transplant recipients treated with tacrolimus. Elens L, Sombogaard F, Hesselink DA, van Schaik RH, van Gelder T

Background: New-onset diabetes after transplantation (NODAT) is an important complication after kidney transplantation. The etiology of the malady is multifactorial and includes both environmental and genetic factors. NODAT is a polygenic disease and many single-nucleotide polymorphisms could constitute potential risk factors. Peroxisome proliferator-activated receptor α (PPARα) and P450 oxidoreductase (POR) play a central role in the control of energy metabolism in humans. Some recent data high... Abstract

Cited 5 times since 2013 (0.4 per year) source: EuropePMC

European journal of emergency medicine : official journal of the European Society for Emergency Medicine, Volume 20, Issue 6, 1 1 2013, Pages 402-407 EEG as a part of the decision-making process in the emergency department. Yigit O, Eray O, Mihci E, Yilmaz D, Eray B, Özkaynak S

Study objective: Although electroencephalography (EEG) is a useful diagnostic tool for patients with a suspected seizure, its value in informing the acute care of patients in the emergency department (ED) remains unclear. The aim of this study is to determine the effects of EEG results on subsequent patient management in or from the ED. Materials and methods: This prospective observational study was carried out in the ED of a tertiary-care university hospital. All patients presenting to the ED w... Abstract

Cited 23 times since 2013 (2 per year) source: EuropePMC

Critical care medicine, Volume 41, Issue 12, 1 1 2013, Pages e401-10 Mild hypothermia attenuates circulatory and pulmonary dysfunction during experimental endotoxemia. Schwarzl M, Seiler S, Wallner M, von Lewinski D, Huber S, Maechler H, Steendijk P, Zelzer S, Truschnig-Wilders M, Obermayer-Pietsch B, Lueger A, Pieske BM, Post H

Objective: We tested whether mild hypothermia impacts on circulatory and respiratory dysfunction during experimental endotoxemia. Design: Randomized controlled prospective experimental study. Setting: Large animal facility, Medical University of Graz, Austria. Subjects: Thirteen anesthetized and mechanically ventilated pigs. Interventions: Lipopolysaccharide was administered for 4 hours. With the beginning of lipopolysaccharide infusion, animals were assigned to either normothermia (38°C, n = 7)... Abstract

Cited 87 times since 2013 (7.6 per year) source: EuropePMC

Mediators of inflammation, Volume 2013, 30 5 2013, Pages 206039 Danger signals in the initiation of the inflammatory response after myocardial infarction. de Haan JJ, Smeets MB, Pasterkamp G, Arslan F

During myocardial infarction, sterile inflammation occurs. The danger model is a solid theoretic framework that explains this inflammation as danger associated molecular patterns activate the immune system. The innate immune system can sense danger signals through different pathogen recognition receptors (PRR) such as toll-like receptors, nod-like receptors and receptors for advanced glycation endproducts. Activation of a PRR results in the production of cytokines and the recruitment of leukocyt... Abstract

Cited 12 times since 2013 (1 per year) source: EuropePMC

Arrhythmia & electrophysiology review, Volume 2, Issue 2, 29 5 2013, Pages 128-134 Imaging-guided Ventricular Tachycardia Ablation. Piers SR, Zeppenfeld K

Over the past decades important advances have been made in the field of ventricular tachycardia (VT) ablation, and as a result, VT ablation is now more widely being performed. The identification of ablation target sites still relies on electroanatomical substrate mapping, which is time-consuming, hampered by the intramural location of some scars and limited by epicardial fat. The potential of various imaging modalities to overcome these limitations have stimulated clinical electrophysiologists t... Abstract

Cited 21 times since 2013 (1.8 per year) source: EuropePMC

Veterinary microbiology, Volume 168, Issue 2-4, 28 4 2013, Pages 281-293 Schmallenberg virus in Dutch dairy herds: potential risk factors for high within-herd seroprevalence and malformations in calves, and its impact on productivity. Veldhuis AM, Carp-van Dijken S, van Wuijckhuise L, Witteveen G, van Schaik G

In November 2011, the new orthobunyavirus Schmallenberg virus (SBV) was identified in dairy cows that had induced fever, drop in milk production and diarrhoea in the Netherlands (Muskens et al., 2012. Tijdschrift voor Diergeneeskunde 137, 112-115) and a drop in milk production in cows in Northwestern Germany (Hoffmann et al., 2012. Emerging Infectious Diseases 18 (3), 469-472), in August/September 2011. This study aimed at quantifying risk factors for high within-herd prevalence of SBV and SBV-i... Abstract

Cited 15 times since 2013 (1.3 per year) source: EuropePMC

Journal of electrocardiology, Volume 47, Issue 2, 27 4 2013, Pages 183-190 Acute coronary syndrome with a totally occluded culprit artery: relation of the ST injury vector with ST-elevation and non-ST elevation ECGs. Man S, Rahmattulla C, Maan AC, van der Putten NH, Dijk WA, van Zwet EW, van der Wall EE, Schalij MJ, Gorgels AP, Swenne CA

Background: In acute coronary syndrome (ACS), ST-segment elevation (STE), often associated with a completely occluded culprit artery, is an important ECG criterion for primary percutaneous coronary intervention (PCI). However, several studies showed that in ACS a completely occluded culprit artery can also occur with a non-ST-elevation (NSTE) ECG. In order to elucidate reasons for this discrepancy we examined ST injury vector orientation and magnitude in ACS patients with and without STE, all ad... Abstract

Cited 2 times since 2013 (0.2 per year) source: EuropePMC

Frontiers in psychology, Volume 4, 26 4 2013, Pages 883 Visual attention for a desktop virtual environment with ambient scent. Toet A, van Schaik MG

In the current study participants explored a desktop virtual environment (VE) representing a suburban neighborhood with signs of public disorder (neglect, vandalism, and crime), while being exposed to either room air (control group), or subliminal levels of tar (unpleasant; typically associated with burned or waste material) or freshly cut grass (pleasant; typically associated with natural or fresh material) ambient odor. They reported all signs of disorder they noticed during their walk togethe... Abstract

Cited 11 times since 2013 (1 per year) source: EuropePMC

Breast cancer research and treatment, Volume 143, Issue 1, 22 4 2013, Pages 171-179 CYP2D6 genotype in relation to hot flashes as tamoxifen side effect in a Dutch cohort of the tamoxifen exemestane adjuvant multinational (TEAM) trial. Dezentjé VO, Gelderblom H, Van Schaik RH, Vletter-Bogaartz JM, Van der Straaten T, Wessels JA, Kranenbarg EM, Berns EM, Seynaeve C, Putter H, Van de Velde CJ, Nortier JW, Guchelaar HJ

In tamoxifen-treated breast cancer patients the occurrence of hot flashes may be associated with effective estrogen receptor antagonism dependent on genetic variations of metabolic enzymes and the estrogen receptor. Early breast cancer patients who were randomized to receive tamoxifen, followed by exemestane within the tamoxifen exemestane adjuvant multinational trial were genotyped for five CYP2D6 alleles. CYP2D6 genotypes and phenotypes were related to the occurrence of hot flashes as adverse... Abstract

Cited 2 times since 2013 (0.2 per year) source: EuropePMC

Frontiers in neuroscience, Volume 7, 15 3 2013, Pages 212 The ripple pond: enabling spiking networks to see. Afshar S, Cohen GK, Wang RM, Van Schaik A, Tapson J, Lehmann T, Hamilton TJ

We present the biologically inspired Ripple Pond Network (RPN), a simply connected spiking neural network which performs a transformation converting two dimensional images to one dimensional temporal patterns (TP) suitable for recognition by temporal coding learning and memory networks. The RPN has been developed as a hardware solution linking previously implemented neuromorphic vision and memory structures such as frameless vision sensors and neuromorphic temporal coding spiking neural networks... Abstract

Cited 19 times since 2013 (1.6 per year) source: EuropePMC

Thyroid : official journal of the American Thyroid Association, Volume 24, Issue 2, 13 2 2013, Pages 208-214 Subclinical thyroid dysfunction and functional capacity among elderly. Virgini VS, Wijsman LW, Rodondi N, Bauer DC, Kearney PM, Gussekloo J, den Elzen WP, Jukema JW, Westendorp RG, Ford I, Stott DJ, Mooijaart SP, PROSPER Study Group

Background: Subclinical thyroid dysfunction is common among older people and has been associated with decreased functional capacity but with conflicting data. The aim of this study was to assess the association between subclinical thyroid dysfunction and functional capacity in an elderly population. Methods: We included 5182 participants with a mean age of 75.2 years from the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER). Self-reported functional capacity was assessed using t... Abstract

Cited 46 times since 2013 (4 per year) source: EuropePMC

General and comparative endocrinology, Volume 195, 13 2 2013, Pages 151-156 Hair as a long-term retrospective cortisol calendar in orang-utans (Pongo spp.): new perspectives for stress monitoring in captive management and conservation. Carlitz EH, Kirschbaum C, Stalder T, van Schaik CP

This study examined whether the method of hair cortisol analysis is applicable to orang-utans (Pongo spp.) and can help to advance the objective monitoring of stress in non-human primates. Specifically, we examined whether fundamental prerequisites for hair cortisol analysis are given in orang-utans and, subsequently, whether segmental hair analysis may provide a retrospective calendar of long-term cortisol levels. For this, hair samples were examined from 71 zoo-living orang-utans (38 males, me... Abstract

Cited 65 times since 2013 (5.6 per year) source: EuropePMC

PloS one, Volume 8, Issue 11, 13 2 2013, Pages e80017 Linkage to HIV, TB and non-communicable disease care from a mobile testing unit in Cape Town, South Africa. Govindasamy D, Kranzer K, van Schaik N, Noubary F, Wood R, Walensky RP, Freedberg KA, Bassett IV, Bekker LG

Background: HIV counseling and testing may serve as an entry point for non-communicable disease screening. Objectives: To determine the yield of newly-diagnosed HIV, tuberculosis (TB) symptoms, diabetes and hypertension, and to assess CD4 count testing, linkage to care as well as correlates of linkage and barriers to care from a mobile testing unit. Methods: A mobile unit provided screening for HIV, TB symptoms, diabetes and hypertension in Cape Town, South Africa between March 2010 and Septembe... Abstract

Cited 106 times since 2013 (9.2 per year) source: EuropePMC

The lancet. Diabetes & endocrinology, Volume 2, Issue 3, 12 2 2013, Pages 210-217 Brown adipose tissue volume in healthy lean south Asian adults compared with white Caucasians: a prospective, case-controlled observational study. Bakker LE, Boon MR, van der Linden RA, Arias-Bouda LP, van Klinken JB, Smit F, Verberne HJ, Jukema JW, Tamsma JT, Havekes LM, van Marken Lichtenbelt WD, Jazet IM, Rensen PC

Background: Individuals of south Asian origin have a very high risk of developing type 2 diabetes compared with white Caucasians. We aimed to assess volume and activity of brown adipose tissue (BAT), which is thought to have a role in energy metabolism by combusting fatty acids and glucose to produce heat and might contribute to the difference in incidence of type 2 diabetes between ethnic groups. Methods: We enrolled Dutch nationals with south Asian ancestry and matched Caucasian participants a... Abstract

Cited 8 times since 2013 (0.7 per year) source: EuropePMC

Clinical genitourinary cancer, Volume 12, Issue 3, 12 2 2013, Pages 190-195 Radical cystectomy in a Dutch University hospital: long-term outcomes and prognostic factors in a homogeneous surgery-only series. Bruins HM, Arends TJ, Pelkman M, Hulsbergen-van de Kaa CA, van der Heijden AG, Witjes JA

Background: The aim of this study was to present survival outcomes and identify prognostic factors in patients undergoing radical cystectomy (RC) for urothelial bladder cancer (UBC) in a homogeneous surgery-only series. Patients and methods: Patients who underwent RC for UBC with intent-to-cure between January 1998 and December 2010 without neoadjuvant or adjuvant treatment were included in this retrospective study. Clinical and histopathologic data were collected and institutional review board... Abstract

Cited 46 times since 2013 (4 per year) source: EuropePMC

Psychological research, Volume 78, Issue 6, 8 2 2013, Pages 878-891 Optimal training design for procedural motor skills: a review and application to laparoscopic surgery. Spruit EN, Band GP, Hamming JF, Ridderinkhof KR

This literature review covers the choices to consider in training complex procedural, perceptual and motor skills. In particular, we focus on laparoscopic surgery. An overview is provided of important training factors modulating the acquisition, durability, transfer, and efficiency of trained skills. We summarize empirical studies and their theoretical background on the topic of training complex cognitive and motor skills that are pertinent to proficiency in laparoscopic surgery. The overview pe... Abstract

Cited 3 times since 2013 (0.3 per year) source: EuropePMC

PloS one, Volume 8, Issue 11, 8 2 2013, Pages e78721 No effect of ambient odor on the affective appraisal of a desktop virtual environment with signs of disorder. Toet A, van Schaik M, Theunissen NC

Background: Desktop virtual environments (VEs) are increasingly deployed to study the effects of environmental qualities and interventions on human behavior and safety related concerns in built environments. For these applications it is essential that users appraise the affective qualities of the VE similar to those of its real world counterpart. Previous studies have shown that factors like simulated lighting, sound and dynamic elements all contribute to the affective appraisal of a desktop VE.... Abstract

Cited 21 times since 2013 (1.8 per year) source: EuropePMC

IEEE transactions on biomedical circuits and systems, Volume 8, Issue 4, 8 2 2013, Pages 453-464 Asynchronous binaural spatial audition sensor with 2 × 64 × 4 channel output. Liu SC, van Schaik A, Minch BA, Delbruck T

This paper proposes an integrated event-based binaural silicon cochlea system aimed at efficient spatial audition and auditory scene analysis. The cochlea chip has a matched pair of digitally-calibrated 64-stage cascaded analog second-order filter banks with 512 pulse-frequency modulated (PFM) address-event representation (AER) outputs. The quality factors (Qs) of channels are individually adjusted by local DACs. The 2P4M 0.35 um CMOS chip consumes an average power of 14 mW including its integra... Abstract