8593 results
Cited 24 times since 2012 (1.9 per year)
source: EuropePMC
BMC infectious diseases,
Volume 12, 14 2 2012, Pages 302
Decolonization of patients and health care workers to control nosocomial spread of methicillin-resistant Staphylococcus aureus: a simulation study.
Gurieva TV, Bootsma MC, Bonten MJ
Background: Control of methicillin-resistant Staphylococcus aureus (MRSA) transmission has been unsuccessful in many hospitals. Recommended control measures include isolation of colonized patients, rather than decolonization of carriage among patients and/or health care workers. Yet, the potential effects of such measures are poorly understood. Methods: We use a stochastic simulation model in which health care workers can transmit MRSA through short-lived hand contamination, or through persisten...
Abstract
Cited 11 times since 2012 (0.9 per year)
source: EuropePMC
European journal of heart failure,
Volume 15, Issue 4, 9 2 2012, Pages 400-407
Heart failure determines the myocardial inflammatory response to injury.
Kortekaas KA, Lindeman JH, Versteegh MI, van Beelen E, Kleemann R, Klautz RJ
Aims: Systemic complications after cardiac surgery are common in heart failure patients. However, the pathophysiological mechanisms, such as a different local inflammatory response of failing hearts, remain in question. This study examines whether failing hearts respond differently to cardioplegic arrest and reperfusion compared with non-failing hearts (controls). Methods and results: The inflammatory response was evaluated in samples collected simultaneously from the radial artery and coronary...
Abstract
Cited 36 times since 2012 (2.9 per year)
source: EuropePMC
Diabetes care,
Volume 36, Issue 2, 8 2 2012, Pages 457-462
Right ventricular involvement in diabetic cardiomyopathy.
Widya RL, van der Meer RW, Smit JW, Rijzewijk LJ, Diamant M, Bax JJ, de Roos A, Lamb HJ
Objective: To compare magnetic resonance imaging-derived right ventricular (RV) dimensions and function between men with type 2 diabetes and healthy subjects, and to relate these parameters to left ventricular (LV) dimensions and function. Research design and methods: RV and LV volumes and functions were assessed in 78 men with uncomplicated type 2 diabetes and 28 healthy men within the same range of age using magnetic resonance imaging. Steady-state free precession sequences were used to assess...
Abstract
Cited 1 times since 2012 (0.1 per year)
source: EuropePMC
Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery,
Volume 41, Issue 3, 3 1 2012, Pages 242-244
Nasal folliculosebaceous hamartoma with vascular-mesenchymal overgrowth in an infant.
Selçuk ÖT, Osma U, Süren D, Eyigör H, Yılmaz D, Sezer C
The nasal hamartoma is a rare non-neoplastic malformation or inborn error of tissue development, characterized by a mix of several tissue types. Folliculosebaceous cystic hamartoma is a distinct type of cutaneous hamartoma. We present a 3-month-old male infant who had nasal obstruction and who had a diagnosis of nasal folliculosebaceous cystic hamartoma after surgery.
Abstract
Cited 54 times since 2012 (4.3 per year)
source: EuropePMC
Journal of hepato-biliary-pancreatic sciences,
Volume 19, Issue 6, 1 1 2012, Pages 626-637
Image-guided hepatopancreatobiliary surgery using near-infrared fluorescent light.
Verbeek FP, van der Vorst JR, Schaafsma BE, Hutteman M, Bonsing BA, van Leeuwen FW, Frangioni JV, van de Velde CJ, Swijnenburg RJ, Vahrmeijer AL
Background: Improved imaging methods and surgical techniques have created a new era in hepatopancreatobiliary (HPB) surgery. Despite these developments, visual inspection, palpation, and intraoperative ultrasound remain the most utilized tools during surgery today. This is problematic, though, especially in laparoscopic HPB surgery, where palpation is not possible. Optical imaging using near-infrared (NIR) fluorescence can be used for the real-time assessment of both anatomy (e.g., sensitive det...
Abstract
Cited 3 times since 2012 (0.2 per year)
source: EuropePMC
Planta medica,
Volume 78, Issue 18, 31 5 2012, Pages 1918-1926
Antibiofilm activity of Dendrophthoe falcata against different bacterial pathogens.
Karthikeyan A, Rameshkumar R, Sivakumar N, Al Amri IS, Karutha Pandian S, Ramesh M
Dendrophthoe falcata is a hemiparasitic plant commonly used for ailments such as ulcers, asthma, impotence, paralysis, skin diseases, menstrual troubles, pulmonary tuberculosis, and wounds. In this context, the validations of the traditional claim that the leaf extract of D. falcata possesses antibiofilm and anti-quorum sensing activity against different bacterial pathogens were assessed. The bacterial biofilms were quantified by crystal violet staining. Among the 17 bacterial pathogens screened...
Abstract
Cited 1 times since 2012 (0.1 per year)
source: EuropePMC
European biophysics journal : EBJ,
Volume 42, Issue 4, 23 4 2012, Pages 241-255
Depolarization-induced automaticity in rat ventricular cardiomyocytes is based on the gating properties of L-type calcium and slow Kv channels.
Ypey DL, van Meerwijk WP, Umar S, Pijnappels DA, Schalij MJ, van der Laarse A
Depolarization-induced automaticity (DIA) of cardiomyocytes is the property of those cells to generate pacemaker cell-like spontaneous electrical activity when subjected to a depolarizing current. This property provides a candidate mechanism for generation of pathogenic ectopy in cardiac tissue. The purpose of this study was to determine the biophysical mechanism of DIA in terms of the ion conductance properties of the cardiomyocyte membrane. First, we determined, by use of the conventional whol...
Abstract
Cited 6 times since 2012 (0.5 per year)
source: EuropePMC
Journal of plastic, reconstructive & aesthetic surgery : JPRAS,
Volume 66, Issue 1, 23 4 2012, Pages e26-8
Associated anomalies and diagnostic approach in lumbosacral and perineal haemangiomas: case report and review of the literature.
de Graaf M, Pasmans SG, van Drooge AM, Nievelstein RA, Gooskens RH, Raphael MF, Breugem CC
Abstract
Cited 30 times since 2012 (2.4 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 5, Issue 6, 22 4 2012, Pages 1059-1063
Prevalence and presentation of externalized conductors and electrical abnormalities in Riata defibrillator leads after fluoroscopic screening: report from the Netherlands Heart Rhythm Association Device Advisory Committee.
Theuns DA, Elvan A, de Voogt W, de Cock CC, van Erven L, Meine M
Background: The Riata family of implantable cardioverter-defibrillator (ICD) leads is prone to a specific insulation abrasion characterized by externalization of conductor cables. The objective of this study was to determine the prevalence of externalized conductors and electrical abnormalities in Riata ICD leads by fluoroscopic screening and standard ICD interrogation. Methods and results: All ICD implantation centers were contacted by the Netherlands Heart Rhythm Association Device Advisory Co...
Abstract
Cited 6 times since 2012 (0.5 per year)
source: EuropePMC
Case reports in urology,
Volume 2012, 16 3 2012, Pages 193787
Synchronous penile metastasis from a high-grade adenocarcinoma of the prostate.
Dijkstra S, van der Heijden AG, Schaafsma HE, Mulders PF
Metastasis to the glans penis is a rare phenomenon and usually occurs in a late stage of disease. A 68-year-old man was referred to our clinic because of two indurated lesions of the glans penis and minor lower urinary tract symptoms. Digital rectal examination revealed a hard nodular prostate, and serum prostate-specific antigen (sPSA) level was 13.3 ng/mL. Biopsies of the penile lesions and transrectal ultrasound-guided prostate biopsies were taken. Immunohistochemical staining of formalin-fix...
Abstract
Cited 18 times since 2012 (1.4 per year)
source: EuropePMC
American heart journal,
Volume 164, Issue 5, 16 3 2012, Pages 771-778
Intramyocardial injection of bone marrow mononuclear cells in chronic myocardial ischemia patients after previous placebo injection improves myocardial perfusion and anginal symptoms: an intra-patient comparison.
Rodrigo SF, van Ramshorst J, Beeres SL, Al Younis I, Dibbets-Schneider P, de Roos A, Fibbe WE, Zwaginga JJ, Schalij MJ, Bax JJ, Atsma DE
Background: We recently demonstrated in a randomized, double-blind, placebo-controlled trial that intramyocardial bone marrow cell (BMC) injection is associated with improvements in myocardial perfusion and anginal symptoms in chronic myocardial ischemia patients. In the present study the results of the crossover phase of this trial, in which patients previously treated with placebo received autologous BMC injections are reported. This allows a unique intra-patient comparison on the effect of BM...
Abstract
Cited 3 times since 2012 (0.2 per year)
source: EuropePMC
PloS one,
Volume 7, Issue 10, 16 3 2012, Pages e46356
Fractional flow reserve is not associated with inflammatory markers in patients with stable coronary artery disease.
Sels JW, Elsenberg EH, Hoefer IE, van Zonneveld AJ, Kuiper J, Jukema JW, Pijls NH, Pasterkamp G
Background: Atherosclerosis is an inflammatory condition and increased blood levels of inflammatory biomarkers have been observed in acute coronary syndromes. In addition, high expression of inflammatory markers is associated with worse prognosis of coronary artery disease. The presence and extent of inducible ischemia in patients with stable angina has previously been shown to have strong prognostic value. We hypothesized that evidence of inducible myocardial ischemia by local lesions, as measu...
Abstract
Cited 40 times since 2012 (3.2 per year)
source: EuropePMC
Cardiovascular research,
Volume 97, Issue 2, 14 2 2012, Pages 311-320
Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft disease.
de Vries MR, Wezel A, Schepers A, van Santbrink PJ, Woodruff TM, Niessen HW, Hamming JF, Kuiper J, Bot I, Quax PH
Aims: Failure of vein graft conduits due to vein graft thickening, accelerated atherosclerosis, and subsequent plaque rupture is applicable to 50% of all vein grafts within 10 years. New potential therapeutic targets to treat vein graft disease may be found in components of the innate immune system, such as mast cells and complement factors, which are known to be involved in atherosclerosis and plaque destabilization. Interestingly, mast cells can be activated by complement factor C5a and, there...
Abstract
Cited 56 times since 2012 (4.4 per year)
source: EuropePMC
Heart rhythm,
Volume 10, Issue 2, 13 2 2012, Pages 158-164
Electrophysiological characteristics of ventricular tachyarrhythmias in cardiac sarcoidosis versus arrhythmogenic right ventricular cardiomyopathy.
Dechering DG, Kochhäuser S, Wasmer K, Zellerhoff S, Pott C, Köbe J, Spieker T, Piers SR, Bittner A, Mönnig G, Breithardt G, Wichter T, Zeppenfeld K, Eckardt L
Background: Recent evidence suggests that cardiac sarcoidosis (CS) and arrhythmogenic right ventricular cardiomyopathy (ARVC) can manifest very similarly. Objective: To investigate whether there are significant demographic and electrophysiological differences between patients with CS and ARVC. Methods: We prospectively compared patients with proven CS or ARVC who underwent radiofrequency catheter ablation of ventricular tachycardias by using 3-dimensional electroanatomical mapping. Furthermore,...
Abstract
Cited 12 times since 2012 (0.9 per year)
source: EuropePMC
Experimental physiology,
Volume 98, Issue 3, 12 2 2012, Pages 710-721
The identification of genetic pathways involved in vascular adaptations after physical deconditioning versus exercise training in humans.
Lammers G, van Duijnhoven NT, Hoenderop JG, Horstman AM, de Haan A, Janssen TW, de Graaf MJ, Pardoel EM, Verwiel ET, Thijssen DH, Hopman MT
Physical inactivity and exercise training result in opposite adaptations of vascular structure. However, the molecular mechanisms behind these adaptations are not completely understood. We used a unique study design to examine both vascular characteristics of the superficial femoral artery (using ultrasound) and gene expression levels (from a muscle biopsy) in human models for physical deconditioning and exercise training. Initially, we compared able-bodied control subjects (n = 6) with spinal c...
Abstract
Cited 38 times since 2012 (3 per year)
source: EuropePMC
PloS one,
Volume 7, Issue 10, 11 2 2012, Pages e46855
Risk of cardiovascular disease in a traditional African population with a high infectious load: a population-based study.
Koopman JJ, van Bodegom D, Jukema JW, Westendorp RG
Background: To test the inflammatory origin of cardiovascular disease, as opposed to its origin in western lifestyle. Population-based assessment of the prevalences of cardiovascular risk factors and cardiovascular disease in an inflammation-prone African population, including electrocardiography and ankle-arm index measurement. Comparison with known prevalences in American and European societies. Methodology/principal findings: Traditional population in rural Ghana, characterised by adverse env...
Abstract
Cited 36 times since 2012 (2.8 per year)
source: EuropePMC
PloS one,
Volume 7, Issue 10, 11 2 2012, Pages e47134
Plaque rupture complications in murine atherosclerotic vein grafts can be prevented by TIMP-1 overexpression.
de Vries MR, Niessen HW, Löwik CW, Hamming JF, Jukema JW, Quax PH
The current study describes the incidence and phenotype of plaque rupture complications in murine vein grafts. Since matrix metalloproteinases (MMPs) are highly involved in atherosclerotic plaque vulnerability and plaque rupture, we hypothesized that this model can be validated by overexpression of the MMP inhibitor TIMP-1. First we studied 47 vein grafts in hypercholesterolemic ApoE3*Leiden mice for the incidence of plaque complications. In 79% of these grafts, extensive lesions with plaque rup...
Abstract
Cited 12 times since 2012 (0.9 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 60, Issue 19, 10 2 2012, Pages 1991-1992
Does pregnancy influence the durability of human aortic valve substitutes?
Arabkhani B, Heuvelman HJ, Bogers AJ, Mokhles MM, Roos-Hesselink JW, Takkenberg JJ
Abstract
Cited 1 times since 2012 (0.1 per year)
source: EuropePMC
Cardiology in the young,
Volume 23, Issue 4, 2 1 2012, Pages 540-545
Peri-operative care in adults with congenital heart disease: room for improvement in after care.
Schoormans D, Smets EM, Zwart R, Sprangers MA, Veelenturg TH, de Mol BA, Hazekamp MG, Koolbergen DR, Sojak V, Bouma BJ, Groenink M, Boekholdt MS, Backx AP, Mulder BJ
Background: Patient satisfaction with care has received little attention within the field of congenital heart disease. Our objective was to examine patient satisfaction with the care received when undergoing open-heart surgery in order to identify the best and worst aspects of peri-operative care. Moreover, we examined whether having contact with a specialised nurse in addition to usual care is associated with higher patient satisfaction levels. Methods: Patient satisfaction was measured by the...
Abstract
Expert review of cardiovascular therapy,
Volume 10, Issue 10, 1 1 2012, Pages 1197-1199
Primary prevention implantable cardioverter-defibrillator treatment: how to identify patients most likely to benefit?
Thijssen J, van Rees JB, Schalij MJ, Borleffs CJ
Abstract
