9618 results
Cited 5 times since 1997 (0.2 per year)
source: EuropePMC
European heart journal,
Volume 18, Issue 8, 1 1 1997, Pages 1313-1321
Beneficial effect of enalapril on left ventricular remodelling in patients with a severe residual stenosis after acute anterior wall infarction.
Baur LH, Schipperheyn JJ, van der Wall EE, van der Velde EA, Schalij MJ, van Eck-Smit BL, van der Laarse A, Voogd PJ, Sedney MI, Reiber JH, Bruschke AV
Objective: The present study was designed to evaluate the effects of early angiotensin converting enzyme (ACE) inhibition on left ventricular enlargement in patients with anterior wall infarction following reperfusion therapy. Methods: Seventy-one consecutive patients with an anterior wall myocardial infarction were randomly allocated to enalapril (n = 36) or placebo (n = 35). All patients received either thrombolytic therapy (n = 46) or underwent primary coronary angioplasty (n = 25). Medicatio...
Abstract
Cited 5 times since 1997 (0.2 per year)
source: EuropePMC
Biology of reproduction,
Volume 57, Issue 1, 1 1 1997, Pages 77-84
Effects of progesterone on the secondary surge of follicle-stimulating hormone in the rat.
Tébar M, Uilenbroek JT, Kramer P, van Schaik RH, Wierikx CD, Ruiz A, de Jong FH, Sánchez-Criado JE
In the cyclic rat, the secondary surge of FSH on estrus appears to depend on the LH surge-induced fall in serum concentrations of inhibin. To investigate the involvement of progesterone in the regulation of the secondary surge of FSH, 4-day cyclic rats were treated on proestrus with an antagonist of LHRH (LHRHant) and with an ovulatory dose of ovine (o) LH, progesterone, the antiprogestin RU486, or the combination of RU486 and oLH. Serum concentrations of gonadotropins and inhibin at 1830 h on p...
Abstract
Cited 9 times since 1997 (0.3 per year)
source: EuropePMC
European journal of pediatrics,
Volume 156, Issue 7, 1 1 1997, Pages 516-520
The value of MRI in diagnosing vascular abnormalities causing stridor.
Beekman RP, Beek FJ, Hazekamp MG, Meijboom EJ
Unlabelled: In a 2 year period seven patients who presented with stridor, without respiratory compromise, and three patients without obstructive symptoms were prospectively selected, and underwent MRI. In eight patients with a vascular ring and a pulmonary sling, MRI delineated the vascular abnormality and normal great vessels were found in two patients. Conclusion: MRI successfully delineates the great vessels and demonstrates the presence of a vascular ring and pulmonary sling.
Abstract
Cited 60 times since 1997 (2.1 per year)
source: EuropePMC
Endocrinology,
Volume 138, Issue 7, 1 1 1997, Pages 2928-2936
Inhibin interferes with activin signaling at the level of the activin receptor complex in Chinese hamster ovary cells.
Martens JW, de Winter JP, Timmerman MA, McLuskey A, van Schaik RH, Themmen AP, de Jong FH
To gain more insight in the mechanism of action of inhibin, we studied the effect of inhibin on activin signaling in Chinese hamster ovary cells. Inhibin specifically counteracted activin-induced expression of a plasminogen activator inhibitor 1 promoter element (3TP) and of the junB gene, but was ineffective when the responses were induced by transforming growth factor-beta. This indicates that inhibin acts only on the activin-specific part of these signaling cascades. Using a constitutively ac...
Abstract
Cited 14 times since 1997 (0.5 per year)
source: EuropePMC
Journal of clinical immunology,
Volume 17, Issue 4, 1 1 1997, Pages 301-310
The growth arresting effect of human immunoglobulin for intravenous use is mediated by antibodies recognizing membrane glycolipids.
Vuist WM, Van Schaik IN, Van Lint M, Brand A
Intravenous human IgG (IVIg) given to patients with autoimmune disorders can result in significant clinical improvement in some patients. The mechanism(s) by which IVIg induces these improvements is(are) not known. We have previously shown that IVIg inhibited the proliferation of peripheral blood lymphocytes in allogeneic mixed lymphocyte reactions and of autonomously growing human and mouse cell lines. In an effort to identify the antigen(s) to which the human IgG binds, the human B cell line J...
Abstract
Cited 16 times since 1997 (0.6 per year)
source: EuropePMC
Biochemical and biophysical research communications,
Volume 236, Issue 3, 1 1 1997, Pages 544-548
Autosomal recessive liver phosphorylase kinase deficiency caused by a novel splice-site mutation in the gene encoding the liver gamma subunit (PHKG2).
van Beurden EA, de Graaf M, Wendel U, Gitzelmann R, Berger R, van den Berg IE
To facilitate mutation analysis of patients with an autosomal recessive form of liver phosphorylase kinase deficiency, the genomic structure of the gene encoding the testis/liver gamma subunit (PHKG2) was established. The gene consist of 10 exons. The translation start site is located in exon 2. Analysis of DNA from two female siblings, affected with liver phosphorylase kinase deficiency, by exon specific amplification followed by direct sequencing, revealed a single donor splice site mutation i...
Abstract
Cited 25 times since 1997 (0.9 per year)
source: EuropePMC
Circulation,
Volume 96, Issue 2, 1 1 1997, Pages 429-435
Functional evaluation of lipid-lowering therapy by pravastatin in the Regression Growth Evaluation Statin Study (REGRESS)
Aengevaeren WR, Uijen GJ, Jukema JW, Bruschke AV, van der Werf T
Background: Lipid-lowering therapy during 2 years in the Regression Growth Evaluation Statin Study (REGRESS) was associated with less progression of coronary atherosclerosis in the pravastatin group compared with the placebo group. The effect of lipid-lowering therapy on the functional state of the coronary circulation is less well known. The purpose of this study was to evaluate this effect. Methods and results: In a substudy of REGRESS, 69 patients were randomized to pravastatin or placebo. Th...
Abstract
Cited 9 times since 1997 (0.3 per year)
source: EuropePMC
International journal of cardiac imaging,
Volume 13, Issue 3, 1 1 1997, Pages 179-189
Ischemic heart disease: value of MR techniques.
van der Wall EE, van Rugge FP, Vliegen HW, Reiber JH, de Roos A, Bruschke AV
Background: The cardiovascular applications of magnetic resonance (MR) techniques in coronary artery disease have increased considerably in recent years. Technical advantages of MR imaging are the excellent spatial resolution, the characterization of myocardial tissue, and the potential for three-dimensional imaging. These characteristics allow the accurate assessment of left ventricular mass and volume, the differentiation of infarcted from normal tissue, and the determination of systolic wall...
Abstract
Consciousness and cognition,
Volume 6, Issue 2-3, 1 1 1997, Pages 437-440
Eye movements and attention.
van der Heijden AH, Bem S
Abstract
Cited 1 times since 1997 (0 per year)
source: EuropePMC
Consciousness and cognition,
Volume 6, Issue 2-3, 1 1 1997, Pages 413-428
Successive approximations to an adequate model of attention.
van der Heijden AH, Bem S
Everybody knows the phenomena summarized with the term attention: concentration, focalization, limitation, selection, and intensification (see, e.g., James, 1890/1950). The explanation of these phenomena is, however, a different matter. Problems easily arise with regard to what has to be explained and with regard to the style of explanation. A problem of the first kind is the "methodology of 'bad focus'": the explanation starts with and is fixated on an intuitively striking b...
Abstract
Cited 109 times since 1997 (3.8 per year)
source: EuropePMC
American journal of physical anthropology,
Volume 103, Issue 1, 1 1 1997, Pages 37-68
Intrasexual competition and body weight dimorphism in anthropoid primates.
Plavcan JM, van Schaik CP
Body weight dimorphism in anthropoid primates has been thought to be a consequence of sexual selection resulting from male-male competition for access to mates. However, while monogamous anthropoids show low degrees of weight dimorphism, as predicted by the sexual selection hypothesis, polygynous anthropoids show high variation in weight dimorphism that is not associated with measures of mating system or sex ratio. This observation has led many to debate the role of other factors such as dietary...
Abstract
Cited 58 times since 1997 (2 per year)
source: EuropePMC
Immunology,
Volume 91, Issue 1, 1 1 1997, Pages 73-80
Characterization of the mucosal cell-mediated immune response in IL-2 knockout mice before and after the onset of colitis.
McDonald SA, Palmen MJ, Van Rees EP, MacDonald TT
One of the major advances in the understanding of inflammatory bowel disease has been the observation that mice with immunoregulatory defects, such as interleukin-2 knockout (IL-2 -/-) mice, develop spontaneous gut inflammation. Here we have characterized the immune response in the ileum, caecum and colon of these mice before and after the onset of colitis by examining the cellular infiltrate, the cytokines produced by these cells and the mucosal vascular addressin MAdCAM-1. IL-2 -/- mice develo...
Abstract
Cited 150 times since 1997 (5.3 per year)
source: EuropePMC
Proceedings of the National Academy of Sciences of the United States of America,
Volume 94, Issue 11, 1 1 1997, Pages 5843-5847
Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells.
Danen-Van Oorschot AA, Fischer DF, Grimbergen JM, Klein B, Zhuang S, Falkenburg JH, Backendorf C, Quax PH, Van der Eb AJ, Noteborn MH
The chicken anemia virus protein apoptin induces a p53-independent, Bcl-2-insensitive type of apoptosis in various human tumor cells. Here, we show that, in vitro, apoptin fails to induce programmed cell death in normal lymphoid, dermal, epidermal, endothelial, and smooth-muscle cells. However, when normal cells are transformed they become susceptible to apoptosis by apoptin. Long-term expression of apoptin in normal human fibroblasts revealed that apoptin has no toxic or transforming activity i...
Abstract
Cited 81 times since 1997 (2.9 per year)
source: EuropePMC
Journal of human evolution,
Volume 32, Issue 4, 1 1 1997, Pages 345-374
Interpreting hominid behavior on the basis of sexual dimorphism.
Plavcan JM, van Schaik CP
Numerous studies use estimates of sexual dimorphism in canine tooth size and body weight to support speculation about the behavior of australopithecines. However, the range of mating systems inferred for australopithecines encompasses virtually the entire spectrum of mating systems seen among extant anthropoid primates, from monogamy to polygyny characterized by intense male male competition. This variety of opinion can be attributed partly to the unusual combination of high body size dimorphism...
Abstract
Cited 3 times since 1997 (0.1 per year)
source: EuropePMC
Multiple sclerosis (Houndmills, Basingstoke, England),
Volume 3, Issue 2, 1 1 1997, Pages 98-104
Immunomodulation and remyelination: two aspects of human polyclonal immunoglobulin treatment in immune mediated neuropathies?
van Schaik IN, Vermeulen M, Brand A
Intravenous immunoglobulin is used in inflammatory demyelinating diseases of the peripheral as well as the central nervous system. It is not known which mechanism(s) accounts for the beneficial effect observed in these diseases. The immunomodulatory effects of IVIg in two different models of T and B cell activation were investigated. IVIg inhibited a predominantly cellular immune response of the Th 1 type, which was partially reversed by addition of Th 1 cytokines. In contrast, in a model, which...
Abstract
Cited 10 times since 1997 (0.4 per year)
source: EuropePMC
Biochemistry,
Volume 36, Issue 15, 1 1 1997, Pages 4480-4488
Lipoxygenase is irreversibly inactivated by the hydroperoxides formed from the enynoic analogues of linoleic acid.
Nieuwenhuizen WF, Van der Kerk-Van Hoof A, van Lenthe JH, Van Schaik RC, Versluis K, Veldink GA, Vliegenthart JF
Triple bond analogues of natural fatty acids irreversibly inactivate lipoxygenase during their enzymatic conversion [Nieuwenhuizen, W. F., et al. (1995) Biochemistry 34, 10538-10545]. To gain insight into the mechanism of the irreversible inactivation of soybean lipoxygenase-1, we studied the enzymatic conversion of two linoleic acid analogues, 9(Z)-octadec-9-en-12-ynoic acid (9-ODEYA) and 12(Z)-octadec-12-en-9-ynoic acid (12-ODEYA). During the inactivation process, Fe(III)-lipoxygenase converts...
Abstract
Cited 20 times since 1997 (0.7 per year)
source: EuropePMC
Theriogenology,
Volume 47, Issue 6, 1 1 1997, Pages 1275-1295
Equine arteritis virus.
Glaser AL, Chirnside ED, Horzinek MC, de Vries AA
Equine arteritis virus (EAV) is a small, enveloped, positive-stranded RNA virus, in the family Arteriviridae , W.H.ich can infect both horses and donkeys. While the majority of EAV infections are asymptomatic, acutely infected animals may develop a wide range of clinical signs, including pyrexia, limb and ventral edema, depression, rhinitis, and conjunctivitis. The virus may cause abortion and has caused mortality in neonates. After natural EAV infection, most horses develop a solid, long-term i...
Abstract
Cited 7 times since 1997 (0.2 per year)
source: EuropePMC
Spine,
Volume 22, Issue 5, 1 1 1997, Pages 531-536
The facet orientation circle. A new parameter for facet joint angulation in the lower lumbar spine.
van Schaik JP, van Pinxteren B, Verbiest H, Crowe A, Zuiderveld KJ
Study design: A descriptive quantitative evaluation was done of the transverse orientation of the lower lumbar facet joints as measured by computed tomography scanning. Objectives: To evaluate a new parameter for facet joint angulation in the transverse plane (the "facet orientation circle") and to obtain reference values for this new parameter. Summary of background data: In other studies, both in vitro and in vivo, the angulation of the facet joints has been measured in degrees relat...
Abstract
Cited 25 times since 1997 (0.9 per year)
source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
Volume 38, Issue 3, 1 1 1997, Pages 372-376
Iodine-131 therapy in sporadic nontoxic goiter.
de Klerk JM, van Isselt JW, van Dijk A, Hakman ME, Pameijer FA, Koppeschaar HP, Zelissen PM, van Schaik JP, van Rijk PP
Unlabelled: The effect of radioiodine in the treatment of nontoxic goiter is seldom evaluated quantitatively. The aim of this study was threefold: (a) to assess the effect of 131I on goiter volume, (b) to establish a relationship between CT volume reduction and the amount of radioactivity taken up by the thyroid and (b) to assess the precision of scintigraphic thyroid volume measurements. Methods: In 27 patients with sporadic nontoxic goiter, the thyroid volume was estimated from a [99mTc]pertec...
Abstract
Cited 16 times since 1997 (0.6 per year)
source: EuropePMC
Pediatric research,
Volume 41, Issue 3, 1 1 1997, Pages 321-326
Oxidative stress during post-hypoxic-ischemic reperfusion in the newborn lamb: the effect of nitric oxide synthesis inhibition.
Dorrepaal CA, van Bel F, Moison RM, Shadid M, van de Bor M, Steendijk P, Berger HM
Post-hypoxic-ischemic (HI) reperfusion induces endothelium and neurons to produce excessive amounts of nitric oxide and superoxide, leading to peroxynitrite formation, release of protein-bound metal ions (i.e. iron), and cytotoxic oxidants. We produced severe HI in 18 newborn lambs and serially determined plasma prooxidants (non-protein-bound iron), lipid peroxidation (malondialdehyde), and antioxidative capacity [ratio of ascorbic acid/dehydroascorbic acid (AA/DHA), alpha-tocopherol, sulfhydryl...
Abstract
