Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
8086 results
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine, Volume 198, 19 3 2023, Pages 110861 An experimental study on chemical shifts and X-ray intensity ratios. Uğurlu M, Akkuş T, Akbulut O, Demir L, Yılmaz D
In this study, full widths at half maximum (FWHM), asymmetry indexes, chemical shifts (ΔE) and Kβ-to-Kα X-ray intensity ratios of some pure metals (Mn, Fe, Cu and Zn) and some of their oxidized compounds (Mn2O3, Fe2O3, Fe3O4, Cu2O3 and ZnO) were investigated. The samples were excited by 59.54 keV photons emitted from a241Am radioisotopes source and characteristic K X-rays emitted from the samples were counted by a Si(Li) detector. The results have shown that the Kβ-to-Kα X-ray intensity ratios,... Abstract
Cited 5 times since 2023 (2.4 per year) source: EuropePMC
Preventive veterinary medicine, Volume 216, 18 3 2023, Pages 105946 Bayesian diagnostic test evaluation and true prevalence estimation of mycoplasma bovis in dairy herds. Veldhuis A, Aalberts M, Penterman P, Wever P, van Schaik G
The true prevalence of dairy cattle herds with M. bovis infections in the Netherlands is unknown. Previous attempts to estimate prevalences were hampered by the absence of a diagnostic serological test that was validated under field conditions. This study estimated sensitivity and specificity of two commercial serum ELISAs and the true M. bovis herd prevalence using different Bayesian latent class models. A total of 7305 serum samples from 415 randomly chosen dairy herds were collected in fall/w... Abstract
Cited 16 times since 2023 (7.7 per year) source: EuropePMC
The World Allergy Organization journal, Volume 16, Issue 5, 18 3 2023, Pages 100780 Real-world evidence for the effectiveness and safety of dupilumab in patients with CRSwNP after 1 year of therapy. Albrecht T, Sailer MM, Capitani F, van Schaik C, Löwenheim H, Becker S
Objectives: For nearly 3 years, the monoclonal antibody dupilumab has been approved in Germany for the treatment of patients with chronic rhinosinusitis with nasal polyps (CRSwNP). Although efficacy has been demonstrated in large double-blind, placebo-controlled clinical trials, few reports of real-world data on this therapy have been published to date. Methods: Patients with an indication for treatment with dupilumab for CRSwNP were included in the study and followed up every 3 months for a per... Abstract
Cited 1 times since 2023 (0.5 per year) source: EuropePMC
International journal of molecular sciences, Volume 24, Issue 10, 18 3 2023, Pages 8948 Hfe Actions in Kupffer Cells Are Dispensable for Hepatic and Systemic Iron Metabolism. Knoop P, Yilmaz D, Paganoni R, Steele-Perkins P, Gruber A, Akdogan B, Zischka H, Leopold K, Vujić Spasić M
Mutations in the HFE/Hfe gene cause Hereditary Hemochromatosis (HH), a highly prevalent genetic disorder characterized by elevated iron deposition in multiple tissues. HFE acts in hepatocytes to control hepcidin expression, whereas HFE actions in myeloid cells are required for cell-autonomous and systemic iron regulation in aged mice. To address the role of HFE specifically in liver-resident macrophages, we generated mice with a selective Hfe deficiency in Kupffer cells (HfeClec4fCre). The analy... Abstract
Cited 3 times since 2023 (1.4 per year) source: EuropePMC
Open research Europe, Volume 3, 17 3 2023, Pages 82 The DECIDE project: from surveillance data to decision-support for farmers and veterinarians. van Schaik G, Hostens M, Faverjon C, Jensen DB, Kristensen AR, Ezanno P, Frössling J, Dórea F, Jensen BB, Carmo LP, Steeneveld W, Rushton J, Gilbert W, Bearth A, Siegrist M, Kaler J, Ripperger J, Siehler J, de Wit S, Garcia-Morante B, Segalés J, Pardon B, Bokma J, Nielen M
Farmers, veterinarians and other animal health managers in the livestock sector are currently missing sufficient information on prevalence and burden of contagious endemic animal diseases. They need adequate tools for risk assessment and prioritization of control measures for these diseases. The DECIDE project develops data-driven decision-support tools, which present (i) robust and early signals of disease emergence and options for diagnostic confirmation; and (ii) options for controlling the d... Abstract
Cited 5 times since 2023 (2.4 per year) source: EuropePMC
World journal of urology, Volume 41, Issue 7, 17 3 2023, Pages 1829-1835 The accuracy of cystoscopy in predicting muscle invasion in newly diagnosed bladder cancer patients. van Straten CGJI, Bruins MH, Dijkstra S, Cornel EB, Kortleve MDH, de Vocht TF, Kiemeney LALM, van der Heijden AG
Purpose: The prognosis of muscle-invasive bladder cancer (MIBC) has not improved for three decades. Transurethral resection of the bladder tumor (TURBT) is the standard procedure for local tumor staging. TURBT has several limitations, including the spread of tumor cells. Therefore, an alternative is needed in patients with suspected MIBC. Recent studies have shown that mpMRI is very accurate in staging bladder tumors. Because the diagnostic efficacy of urethrocystoscopy (UCS) has been reported a... Abstract
Cited 7 times since 2023 (3.3 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 16, Issue 5, 16 3 2023, Pages e014850 Influence of Obesity on Coronary Artery Disease and Clinical Outcomes in the ADVANCE Registry. Lowenstern A, Ng N, Takagi H, Rymer JA, Koweek LM, Douglas PS, Duran JM, Rabbat M, Pontone G, Fairbairn T, Chinnaiyan K, Berman DS, De Bruyne B, Bax JJ, Akasaka T, Amano T, Nieman K, Rogers C, Kitabata H, Sand NPR, Kawasaki T, Mullen S, Matsuo H, Norgaard BL, Patel MR, Leipsic J, Daubert MA
Background: The relationship between body size and cardiovascular events is complex. This study utilized the ADVANCE (Assessing Diagnostic Value of Noninvasive FFRCT in Coronary Care) Registry to investigate the association between body mass index (BMI), coronary artery disease (CAD), and clinical outcomes. Methods: The ADVANCE registry enrolled patients undergoing evaluation for clinically suspected CAD who had >30% stenosis on cardiac computed tomography angiography. Patients were stratifie... Abstract
The American journal of cardiology, Volume 198, 16 3 2023, Pages 137 Corrigendum to 'Impact of Worsening Heart Failure on Long-Term Prognosis in Patients With Heart Failure With Reduced Ejection Fraction'. Chimed S, Stassen J, Galloo X, Meucci MC, van der Bijl P, Knuuti J, Delgado V, Marsan NA, Bax JJ
Cited 1 times since 2023 (0.5 per year) source: EuropePMC
JACC. Cardiovascular interventions, Volume 16, Issue 15, 16 3 2023, Pages 1950-1952 The Effect of Intravascular Lithotripsy on Cardiac Implantable Electronic Device Function. van Oort MJH, Bingen BO, Al Amri I, van der Kley F, Jukema JW, Montero-Cabezas JM
Cited 2 times since 2023 (1 per year) source: EuropePMC
The American journal of cardiology, Volume 199, 15 3 2023, Pages 100-109 Coronary Volume to Left Ventricular Mass Ratio in Patients With Hypertension. van Rosendael SE, van Rosendael AR, Kuneman JH, Patel MR, Nørgaard BL, Fairbairn TA, Nieman K, Akasaka T, Berman DS, Koweek LMH, Pontone G, Kawasaki T, Sand NPR, Jensen JM, Amano T, Poon M, Øvrehus KA, Sonck J, Rabbat MG, Rogers C, Matsuo H, Leipsic JA, Marsan NA, Jukema JW, Bax JJ, Saraste A, Knuuti J
The coronary vascular volume to left ventricular mass (V/M) ratio assessed by coronary computed tomography angiography (CCTA) is a promising new parameter to investigate the relation of coronary vasculature to the myocardium supplied. It is hypothesized that hypertension decreases the ratio between coronary volume and myocardial mass by way of myocardial hypertrophy, which could explain the detected abnormal myocardial perfusion reserve reported in patients with hypertension. Individuals enrolle... Abstract
Cited 6 times since 2023 (2.9 per year) source: EuropePMC
Annals of cardiothoracic surgery, Volume 12, Issue 3, 15 3 2023, Pages 179-193 Functional and pathomorphological anatomy of the aortic valve and root for aortic valve sparing surgery in tricuspid and bicuspid aortic valves. Jahanyar J, Tsai PI, Arabkhani B, Aphram G, Mastrobuoni S, El Khoury G, de Kerchove L
The aortic valve (AV) is a three-dimensional structure, with leaflets that are suspended within the functional aortic annulus (FAA). These structures (AV and FAA) are therefore intrinsically connected and disease of just one component can independently lead to AV dysfunction. Hence, AV dysfunction can occur in the setting of entirely normal valve leaflets. However, as these structures are functionally inter-connected, disease of one component can lead to abnormalities of the other over time. Thu... Abstract
Cited 6 times since 2023 (2.9 per year) source: EuropePMC
The American journal of cardiology, Volume 198, 15 3 2023, Pages 95-100 Changes in Computed-Tomography-Derived Segmental Left Ventricular Longitudinal Strain After Transcatheter Aortic Valve Implantation. Singh GK, Fortuni F, Kuneman JH, Vollema EM, van der Kley F, Marsan NA, Delgado V, Bax JJ
Patients with severe aortic stenosis (AS) may show left ventricular (LV) apical longitudinal strain sparing. Transcatheter aortic valve implantation (TAVI) improves LV systolic function in patients with severe AS. However, the changes in regional longitudinal strain after TAVI have not been extensively evaluated. This study aimed to characterize the effect of the pressure overload relief after TAVI on LV apical longitudinal strain sparing. A total of 156 patients (mean age 80 ± 7 years, 53% men)... Abstract
Cited 4 times since 2023 (1.9 per year) source: EuropePMC
GeroScience, Volume 45, Issue 6, 13 2 2023, Pages 3165-3174 Exploring the possible causal effects of cardiac blood biomarkers in dementia and cognitive performance: a Mendelian randomization study. Zonneveld MH, Trompet S, Jukema JW, Noordam R
Prospective cohort studies have implied associations between blood levels of troponin T, troponin I, NT-proBNP, GDF15, dementia, and cognitive function, without providing evidence favoring possible causality. We aimed to assess the causal associations of these cardiac blood biomarkers with dementia and cognition using two-sample Mendelian randomization (MR). Independent genetic instruments (p Abstract
Cited 4 times since 2023 (1.9 per year) source: EuropePMC
Frontiers in cardiovascular medicine, Volume 10, 12 2 2023, Pages 1166703 The role and implications of left atrial fibrosis in surgical mitral valve repair as assessed by CMR: the ALIVE study design and rationale. El Mathari S, Kluin J, Hopman LHGA, Bhagirath P, Oudeman MAP, Vonk ABA, Nederveen AJ, Eberl S, Klautz RJM, Chamuleau SAJ, van Ooij P, Götte MJW
Background: Patients with mitral regurgitation (MR) commonly suffer from left atrial (LA) remodeling. LA fibrosis is considered to be a key player in the LA remodeling process, as observed in atrial fibrillation (AF) patients. Literature on the presence and extent of LA fibrosis in MR patients however, is scarce and its clinical implications remain unknown. Therefore, the ALIVE trial was designed to investigate the presence of LA remodeling including LA fibrosis in MR patients prior to and after... Abstract
Cited 4 times since 2023 (1.9 per year) source: EuropePMC
The Journal of prosthetic dentistry, Volume 132, Issue 5, 12 2 2023, Pages 1067.e1-1067.e8 Bond strength of additively manufactured composite resins to dentin and titanium when bonded with dual-polymerizing resin cements. Donmez MB, Çakmak G, Yılmaz D, Schimmel M, Abou-Ayash S, Yilmaz B, Peutzfeldt A
Statement of problem: Additively manufactured composite resins for definitive restorations have been recently introduced. The bond strength between these composite resins and different substrates has not been extensively studied. Purpose: The purpose of this in vitro study was to measure the shear bond strength (SBS) between additively manufactured composite resins and dentin and titanium substrates and compare those with the SBS between subtractively manufactured polymer-infiltrated ceramic and... Abstract
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, Volume 32, Issue 1, 11 2 2023, Pages 43-46 Elastic Deformation Measurement Using Duplex Ultrasound for the Detection of High Aneurysm Sac Pressure Following EVAR. van Genderen OS, van Wissen RC, Hamming JF, van Schaik J, van der Vorst JR
Purpose: To describe the concept of aortic elastic deformation (ED) measurement using duplex ultrasonography (DUS) as a tool for detection of high aneurysm sac pressure following endovascular aortic repair (EVAR). Technique: High aneurysm sac pressure, with or without proven endoleak, will result in a less compressible aneurysm. Using the dual image function in B-mode of the DUS device and a standardized amount of applied probe pressure, ED can be measured. It is defined as the percentage of def... Abstract
Cited 19 times since 2023 (9 per year) source: EuropePMC
The Lancet regional health. Western Pacific, Volume 37, 9 2 2023, Pages 100780 Endemicity and diversification of carbapenem-resistant <i>Acinetobacter baumannii</i> in an intensive care unit. Doughty EL, Liu H, Moran RA, Hua X, Ba X, Guo F, Chen X, Zhang L, Holmes M, van Schaik W, McNally A, Yu Y
Background: Carbapenem-resistant Acinetobacter baumannii (CRAB) is a major public health concern globally. Often studied in the context of hospital outbreaks, little is known about the persistence and evolutionary dynamics of endemic CRAB populations. Methods: A three-month cross-sectional observational study was conducted in a 28-bed intensive care unit (ICU) in Hangzhou, China. A total of 5068 samples were collected from the hospital environment (n = 3985), patients (n = 964) and staff (n = 11... Abstract
Cited 18 times since 2023 (8.5 per year) source: EuropePMC
International journal of molecular sciences, Volume 24, Issue 10, 9 2 2023, Pages 8494 Semaglutide Has Beneficial Effects on Non-Alcoholic Steatohepatitis in Ldlr-/-.Leiden Mice. Inia JA, Stokman G, Morrison MC, Worms N, Verschuren L, Caspers MPM, Menke AL, Petitjean L, Chen L, Petitjean M, Jukema JW, Princen HMG, van den Hoek AM
Semaglutide, a glucagon-like peptide-1 receptor agonist, is an antidiabetic medication that has recently been approved for the treatment of obesity as well. Semaglutide is postulated to be a promising candidate for the treatment of non-alcoholic steatohepatitis (NASH). Here, Ldlr-/-.Leiden mice received a fast-food diet (FFD) for 25 weeks, followed by another 12 weeks on FFD with daily subcutaneous injections of semaglutide or vehicle (control). Plasma parameters were evaluated, livers and heart... Abstract
Cited 4 times since 2023 (1.9 per year) source: EuropePMC
Annals of cardiothoracic surgery, Volume 12, Issue 3, 8 2 2023, Pages 244-252 Three decades of reimplantation of the aortic valve-the Brussels experience. Jahanyar J, de Kerchove L, Arabkhani B, Tsai PI, Aphram G, Mastrobuoni S, El Khoury G
Background: Over the last three decades, the importance of native valve preservation has increasingly become evident. Valve-sparing root replacement procedures, such as the reimplantation or remodeling technique, are therefore being progressively used for aortic root replacement and/or aortic valve repair. Herein, we are summarizing our single-center experience with the reimplantation technique. Methods: We queried our prospective database for aortic valve repair and recruited all adult (≥18 yea... Abstract
Cited 1 times since 2023 (0.5 per year) source: EuropePMC
BMC cardiovascular disorders, Volume 23, Issue 1, 5 1 2023, Pages 238 Impact of a comprehensive cardiac rehabilitation programme versus coronary revascularisation in patients with stable angina pectoris: study protocol for the PRO-FIT randomised controlled trial. Heutinck JM, De Koning IA, Vromen T, Van Geuns RM, Thijssen DHJ, Kemps HMC, PRO-FIT Research Group
Background: Currently, in the majority of patients with stable angina pectoris (SAP) treatment consists of optimal medical treatment, potentially followed by coronary angiography and subsequent coronary revascularisation if necessary". Recent work questioned the effectiveness of these invasive procedures in reducing re-events and improving prognosis. The potential of exercise-based cardiac rehabilitation on clinical outcomes in patients with coronary artery disease is well-known. However, i... Abstract