6196 results
BMC medical education,
Volume 20, Issue 1, 5 1 2020, Pages 250
Refuting misconceptions in medical physiology.
Versteeg M, van Loon MH, Wijnen-Meijer M, Steendijk P
Background: In medical physiology, educators and students face a serious challenge termed misconceptions. Misconceptions are incorrect ideas that do not match current scientific views. Accordingly, they have shown to hamper teaching and learning of physiological concepts. Conceptual Change Theory forms the basis of new teaching and learning practices that may alleviate misconceptions and facilitate critical thinking skills that are essential in becoming knowledgeable, self-regulated health profe...
Abstract
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 28, Issue 5, 4 1 2020, Pages 2343-2345
Hybrid Positron emission tomography/magnetic resonance imaging in viability assessment.
Bax JJ, Ng ACT, Delgado V
Abstract
Cited 4 times since 2020 (0.8 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 28, Issue Suppl 1, 1 1 2020, Pages 115-121
The role of long-term mechanical circulatory support in patients with advanced heart failure.
Felix SEA, de Jonge N, Caliskan K, Birim O, Damman K, Kuijpers M, Tops LF, Palmen M, Ramjankhan FZ
In patients with end-stage heart failure, advanced therapies such as heart transplantation and long-term mechanical circulatory support (MCS) with a left ventricular assist device (LVAD) have to be considered. LVADs can be implanted as a bridge to transplantation or as an alternative to heart transplantation: destination therapy. In the Netherlands, long-term LVAD therapy is gaining importance as a result of increased prevalence of heart failure together with a low number of heart transplantatio...
Abstract
Cited 7 times since 2020 (1.5 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 8, 1 1 2020, Pages 828-832
EACVI survey on the evaluation of infective endocarditis.
Holte E, Dweck MR, Marsan NA, D'Andrea A, Manka R, Stankovic I, Haugaa KH
Aims: To evaluate the diagnosis and imaging of patients with suspected endocarditis and the management in routine clinical practice across Europe, the EACVI Scientific Initiatives Committee performed a survey across European centres. In particular, the routine use of echocardiography, advanced imaging modalities and multidisciplinary team was explored. Methods and results: A total of 100 European Echocardiography Laboratories from 29 different countries responded to the survey, which consisted o...
Abstract
Cited 8 times since 2020 (1.7 per year)
source: EuropePMC
European journal of emergency medicine : official journal of the European Society for Emergency Medicine,
Volume 27, Issue 4, 1 1 2020, Pages 243-244
The new era of chest pain evaluation in the Netherlands.
Backus BE, Tolsma RT, Boogers MJ
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Cardiovascular research,
Volume 116, Issue 10, 1 1 2020, Pages e115-e117
Gender balance at the heart of science.
Small HY, Timoteo AT, Buchanan GL, Gimelli A, Jurcut R, Marsan NA, Schüpke S, Zuhlke L
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
European heart journal,
Volume 41, Issue 30, 1 1 2020, Pages 2828-2829
EHRA 2020 during COVID-19 days.
Burri H, Zeppenfeld K, Heidbuchel H
Abstract
Cited 8 times since 2020 (1.7 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 8, 1 1 2020, Pages 937-938
Echocardiography-computed tomography fusion imaging for guidance of transcatheter tricuspid valve annuloplasty.
Fortuni F, Marques AI, Bax JJ, Ajmone Marsan N, Delgado V
Abstract
Cited 20 times since 2020 (4.2 per year)
source: EuropePMC
JACC. Clinical electrophysiology,
Volume 6, Issue 9, 29 5 2020, Pages 1103-1114
Prevalence and Prognostic Impact of Pathogenic Variants in Patients With Dilated Cardiomyopathy Referred for Ventricular Tachycardia Ablation.
Ebert M, Wijnmaalen AP, de Riva M, Trines SA, Androulakis AFA, Glashan CA, Schalij MJ, Peter van Tintelen J, Jongbloed JDH, Zeppenfeld K
Objectives: This study aimed to assess the frequency of (likely) pathogenic variants (LP/Pv) among dilated cardiomyopathy (DCM) ventricular tachycardia (VT) patients referred for CA and their impact on procedural outcome and long-term prognosis. Background: The prevalence of genetic variants associated with monomorphic VT among DCM is unknown. Methods: Ninety-eight consecutive patients (age 56 ± 15 years; 84% men, left ventricular ejection fraction [LVEF] 39 ± 12%) referred for DCM-VT ablation w...
Abstract
Cited 10 times since 2020 (2.1 per year)
source: EuropePMC
The American journal of cardiology,
Volume 133, 28 4 2020, Pages 39-47
Five-Year Outcomes and Prognostic Value of Feature-Tracking Cardiovascular Magnetic Resonance in Patients Receiving Early Prereperfusion Metoprolol in Acute Myocardial Infarction.
Podlesnikar T, Pizarro G, Fernández-Jiménez R, Montero-Cabezas JM, Sánchez-González J, Bucciarelli-Ducci C, Ajmone Marsan N, Fras Z, Bax JJ, Fuster V, Ibáñez B, Delgado V
The aim of the present study was to investigate the long-term impact of early intravenous metoprolol in ST-segment elevation myocardial infarction (STEMI) patients in terms of left ventricular (LV) strain with feature-tracking cardiovascular magnetic resonance (CMR) and its association with prognosis. A total of 270 patients with first anterior STEMI enrolled in the randomized METOCARD-CNIC clinical trial, assigned to receive up to 15 mg intravenous metoprolol before primary percutaneous coronar...
Abstract
Cited 25 times since 2020 (5.2 per year)
source: EuropePMC
European journal of preventive cardiology,
Volume 28, Issue 1, 27 4 2020, Pages 33-43
Intensity of statin treatment after acute coronary syndrome, residual risk, and its modification by alirocumab: insights from the ODYSSEY OUTCOMES trial.
Diaz R, Li QH, Bhatt DL, Bittner VA, Baccara-Dinet MT, Goodman SG, Jukema JW, Kimura T, Parkhomenko A, Pordy R, Reiner Ž, Roe MT, Szarek M, Tse HF, White HD, Zahger D, Zeiher AM, Schwartz GG, Steg PG, ODYSSEY OUTCOMES Committees and Investigators
Aims: Statins are pivotal to the secondary prevention of major adverse cardiovascular events, but some patients are statin-intolerant. We examined the effects of the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor alirocumab on the risk of major adverse cardiovascular events according to the intensity of background statin treatment. Methods and results: The ODYSSEY OUTCOMES trial compared alirocumab with placebo in 18,924 patients with acute coronary syndrome and dyslipidaemia de...
Abstract
Cited 8 times since 2020 (1.7 per year)
source: EuropePMC
BioMed research international,
Volume 2020, 27 4 2020, Pages 8748934
Blood Monocyte Phenotype Fingerprint of Stable Coronary Artery Disease: A Cross-Sectional Substudy of SMARTool Clinical Trial.
Sbrana S, Campolo J, Clemente A, Bastiani L, Cecchettini A, Ceccherini E, Caselli C, Neglia D, Parodi O, Chiappino D, Smit JM, Scholte AJ, Pelosi G, Rocchiccioli S
Background and aims: Atherosclerosis is an inflammatory disease with long-lasting activation of innate immunity and monocytes are the main blood cellular effectors. We aimed to investigate monocyte phenotype (subset fraction and marker expression) at different stages of coronary atherosclerosis in stable coronary artery disease (CAD) patients. Methods: 73 patients with chronic coronary syndrome were evaluated by CT coronary angiography (CTCA) and classified by maximal diameter stenosis of major...
Abstract
Cited 7 times since 2020 (1.5 per year)
source: EuropePMC
Journal of the American Heart Association,
Volume 9, Issue 15, 25 4 2020, Pages e016990
Prespecified Risk Criteria Facilitate Adequate Discharge and Long-Term Outcomes After Transfemoral Transcatheter Aortic Valve Implantation.
Spence MS, Baan J, Iacovelli F, Martinelli GL, Muir DF, Saia F, Bortone AS, Densem CG, Owens CG, van der Kley F, Vis M, van Mourik MS, Costa G, Sykorova L, Lüske CM, Deutsch C, Kurucova J, Thoenes M, Bramlage P, Tamburino C, Barbanti M
Background Despite the availability of guidelines for the performance of transcatheter aortic valve implantation (TAVI), current treatment pathways vary between countries and institutions, which impact on the mean duration of postprocedure hospitalization. Methods and Results This was a prospective, multicenter registry of 502 patients to validate the appropriateness of discharge timing after transfemoral TAVI, using prespecified risk criteria from FAST-TAVI (Feasibility and Safety of Early Disc...
Abstract
Cited 7 times since 2020 (1.5 per year)
source: EuropePMC
Journal of medical Internet research,
Volume 22, Issue 7, 24 4 2020, Pages e14861
An Internet-Based Psychological Intervention With a Serious Game to Improve Vitality, Psychological and Physical Condition, and Immune Function in Healthy Male Adults: Randomized Controlled Trial.
Schakel L, Veldhuijzen DS, van Middendorp H, Prins C, Drittij AMHF, Vrieling F, Visser LG, Ottenhoff THM, Joosten SA, Evers AWM
Background: Recently, internet-based cognitive behavioral therapy (ICBT) and serious gaming interventions have been suggested to enhance accessibility to interventions and engagement in psychological interventions that aim to promote health outcomes. Few studies, however, have investigated their effectiveness in the context of simulated real-life challenges. Objective: We aimed to examine the effectivity of a guided ICBT combined with a serious gaming intervention in improving self-reported psyc...
Abstract
Cited 67 times since 2020 (14 per year)
source: EuropePMC
Nature,
Volume 583, Issue 7818, 22 4 2020, Pages 801-806
Global status and conservation potential of reef sharks.
MacNeil MA, Chapman DD, Heupel M, Simpfendorfer CA, Heithaus M, Meekan M, Harvey E, Goetze J, Kiszka J, Bond ME, Currey-Randall LM, Speed CW, Sherman CS, Rees MJ, Udyawer V, Flowers KI, Clementi G, Valentin-Albanese J, Gorham T, Adam MS, Ali K, Pina-Amargós F, Angulo-Valdés JA, Asher J, Barcia LG, Beaufort O, Benjamin C, Bernard ATF, Berumen ML, Bierwagen S, Bonnema E, Bown RMK, Bradley D, Brooks E, Brown JJ, Buddo D, Burke P, Cáceres C, Cardeñosa D, Carrier JC, Caselle JE, Charloo V, Claverie T, Clua E, Cochran JEM, Cook N, Cramp J, D'Alberto B, de Graaf M, Dornhege M, Estep A, Fanovich L, Farabaugh NF, Fernando D, Flam AL, Floros C, Fourqurean V, Garla R, Gastrich K, George L, Graham R, Guttridge T, Hardenstine RS, Heck S, Henderson AC, Hertler H, Hueter R, Johnson M, Jupiter S, Kasana D, Kessel ST, Kiilu B, Kirata T, Kuguru B, Kyne F, Langlois T, Lédée EJI, Lindfield S, Luna-Acosta A, Maggs J, Manjaji-Matsumoto BM, Marshall A, Matich P, McCombs E, McLean D, Meggs L, Moore S, Mukherji S, Murray R, Kaimuddin
Decades of overexploitation have devastated shark populations, leaving considerable doubt as to their ecological status1,2. Yet much of what is known about sharks has been inferred from catch records in industrial fisheries, whereas far less information is available about sharks that live in coastal habitats3. Here we address this knowledge gap using data from more than 15,000 standardized baited remote underwater video stations that were deployed on 371 reefs in 58 nations to estimate the conse...
Abstract
Cited 33 times since 2020 (6.9 per year)
source: EuropePMC
Molecular therapy. Nucleic acids,
Volume 21, 21 3 2020, Pages 932-953
Adenosine-to-Inosine Editing of Vasoactive MicroRNAs Alters Their Targetome and Function in Ischemia.
van der Kwast RVCT, Parma L, van der Bent ML, van Ingen E, Baganha F, Peters HAB, Goossens EAC, Simons KH, Palmen M, de Vries MR, Quax PHA, Nossent AY
Adenosine-to-inosine (A-to-I) editing in the seed sequence of microRNAs can shift the microRNAs' targetomes and thus their function. Using public RNA-sequencing data, we identified 35 vasoactive microRNAs that are A-to-I edited. We quantified A-to-I editing of the primary (pri-)microRNAs in vascular fibroblasts and endothelial cells. Nine pri-microRNAs were indeed edited, and editing consistently increased under ischemia. We determined mature microRNA editing for the highest expressed micro...
Abstract
Journal of cardiology,
Volume 76, Issue 5, 19 3 2020, Pages 514-520
QT interval variability and heart rate turbulence are associated with clinical characteristics in congenital heart disease patients with a systemic right ventricle.
Zandstra T, Kiès P, Man SC, Maan A, Bootsma M, Vliegen H, Egorova A, Holman E, Schalij M, Jongbloed M
Background: QT interval variability (QTV) and heart rate turbulence (HRT) are measures of cardiac autonomic function, which, when abnormal, are correlated with ventricular arrhythmias and worse clinical outcome. This study aims to evaluate QTV and HRT in patients with a systemic right ventricle (RV) and to assess correlations with clinical characteristics. Methods: In a retrospective cohort study, QTV and HRT were derived from 24-h Holter registrations of patients with a systemic RV and healthy...
Abstract
Cited 33 times since 2020 (6.9 per year)
source: EuropePMC
Cardiovascular diabetology,
Volume 19, Issue 1, 18 3 2020, Pages 113
Quantitative assessment of coronary plaque volume change related to triglyceride glucose index: The Progression of AtheRosclerotic PlAque DetermIned by Computed TomoGraphic Angiography IMaging (PARADIGM) registry.
Won KB, Lee BK, Park HB, Heo R, Lee SE, Rizvi A, Lin FY, Kumar A, Hadamitzky M, Kim YJ, Sung JM, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Chun EJ, Cademartiri F, Maffei E, Marques H, de Araújo Gonçalves P, Leipsic JA, Shin S, Choi JH, Virmani R, Samady H, Chinnaiyan K, Raff GL, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Min JK, Chang HJ
Background: The association between triglyceride glucose (TyG) index and coronary atherosclerotic change remains unclear. We aimed to evaluate the association between TyG index and coronary plaque progression (PP) using serial coronary computed tomography angiography (CCTA). Methods: A total of 1143 subjects (aged 60.7 ± 9.3 years, 54.6% male) who underwent serial CCTA with available data on TyG index and diabetic status were analyzed from The Progression of AtheRosclerotic PlAque DetermIned by...
Abstract
Cited 5 times since 2020 (1 per year)
source: EuropePMC
Nutrition, metabolism, and cardiovascular diseases : NMCD,
Volume 30, Issue 12, 16 3 2020, Pages 2230-2241
The role of insulin resistance in the relation of visceral, abdominal subcutaneous and total body fat to cardiovascular function.
Paiman EHM, de Mutsert R, Widya RL, Rosendaal FR, Jukema JW, Lamb HJ
Background and aims: The separate cardiovascular effects of type 2 diabetes and adiposity remain to be examined. This study aimed to investigate the role of insulin resistance in the relations of visceral (VAT), abdominal subcutaneous (aSAT) adipose tissue and total body fat (TBF) to cardiovascular remodeling. Methods and results: In this cross-sectional analysis of the population-based Netherlands Epidemiology of Obesity study, 914 middle-aged individuals (46% men) were included. Participants u...
Abstract
Cited 33 times since 2020 (6.9 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 13, Issue 10, 15 3 2020, Pages 2162-2173
A Boosted Ensemble Algorithm for Determination of Plaque Stability in High-Risk Patients on Coronary CTA.
Al'Aref SJ, Singh G, Choi JW, Xu Z, Maliakal G, van Rosendael AR, Lee BC, Fatima Z, Andreini D, Bax JJ, Cademartiri F, Chinnaiyan K, Chow BJW, Conte E, Cury RC, Feuchtner G, Hadamitzky M, Kim YJ, Lee SE, Leipsic JA, Maffei E, Marques H, Plank F, Pontone G, Raff GL, Villines TC, Weirich HG, Cho I, Danad I, Han D, Heo R, Lee JH, Rizvi A, Stuijfzand WJ, Gransar H, Lu Y, Sung JM, Park HB, Berman DS, Budoff MJ, Samady H, Stone PH, Virmani R, Narula J, Chang HJ, Lin FY, Baskaran L, Shaw LJ, Min JK
Objectives: This study sought to identify culprit lesion (CL) precursors among acute coronary syndrome (ACS) patients based on qualitative and quantitative computed tomography-based plaque characteristics. Background: Coronary computed tomography angiography (CTA) has been validated for patient-level prediction of ACS. However, the applicability of coronary CTA to CL assessment is not known. Methods: Utilizing the ICONIC (Incident COroNary Syndromes Identified by Computed Tomography) study, a ne...
Abstract
