7971 results
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 8, 15 3 2022, Pages 779075
Continuum of Care: Positioning of the Virtual Hospital.
van der Lande ACMH, Treskes RW, Beeres SLMA, Schalij MJ
Introduction: Patients with multiple chronic diseases suffer from reduced life expectancy. Care for these patients is often divided over multiple healthcare professionals. eHealth might help to integrate care for these patients and create a continuum. It is the primary purpose of this paper to describe an intervention that integrates first, second, and third line care in patients with multiple chronic conditions using remote monitoring, remote therapy and data automatization, all integrated in a...
Abstract
Cited 8 times since 2022 (2.5 per year)
source: EuropePMC
Cancers,
Volume 14, Issue 6, 15 3 2022, Pages 1494
Impact of <i>BRCA</i> Status on Reproductive Decision-Making and Self-Concept: A Mixed-Methods Study Informing the Development of Tailored Interventions.
Hesse-Biber S, Seven M, Jiang J, Schaik SV, Dwyer AA
This mixed-methods study sought to deepen our understanding of self-concept and experiences in balancing cancer risk/reproductive decisions after learning of BRCA+ status. First, a quantitative survey of BRCA+ women (n = 505) examined the childbearing status, risk-reducing surgery, and self-concept. At the time of testing, 307/505 (60.8%) women were of reproductive age (
Abstract
Cited 3 times since 2022 (0.9 per year)
source: EuropePMC
Journal of the peripheral nervous system : JPNS,
Volume 27, Issue 2, 15 3 2022, Pages 159-165
Analysis of relapse by inflammatory Rasch-built overall disability scale status in the PATH study of subcutaneous immunoglobulin in chronic inflammatory demyelinating polyneuropathy.
Merkies ISJ, van Schaik IN, Bril V, Hartung HP, Lewis RA, Sobue G, Lawo JP, Mielke O, Cornblath DR, PATH study group
Clinical trials in chronic inflammatory demyelinating polyneuropathy (CIDP) often assess efficacy using the ordinal Inflammatory Neuropathy Cause and Treatment (INCAT) disability score. Here, data from the PATH study was reanalyzed using change in Inflammatory Rasch-built Overall Disability Scale (I-RODS) to define CIDP relapse instead of INCAT. The PATH study comprised an intravenous immunoglobulin (IVIG) dependency period and an IVIG (IgPro10 [Privigen]) restabilization period; subjects were t...
Abstract
Cited 16 times since 2022 (5 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 35, Issue 8, 15 3 2022, Pages 791-800.e4
Left Ventricular Global Longitudinal Strain in Patients with Moderate Aortic Stenosis.
Stassen J, Pio SM, Ewe SH, Singh GK, Hirasawa K, Butcher SC, Cohen DJ, Généreux P, Leon MB, Marsan NA, Delgado V, Bax JJ
Moderate aortic stenosis (AS) is associated with an increased risk for adverse events. Although reduced left ventricular (LV) global longitudinal strain (GLS) is associated with worse outcomes in patients with severe AS, its prognostic value in patients with moderate AS is unknown. The aim of this study was to investigate the prognostic implications of LV GLS in patients with moderate AS. Methods: LV GLS was evaluated using speckle-tracking echocardiography in patients with moderate AS (aortic v...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
Medical sciences (Basel, Switzerland),
Volume 10, Issue 1, 15 3 2022, Pages 19
Parathyroid Allotransplantation: A Systematic Review.
Zhang JLH, Appelman-Dijkstra NM, Schepers A
Background: To date, there is no satisfactory treatment for patients with calcium and vitamin D supplementation refractive hypoparathyroidism. Parathyroid allotransplantation by design is a one-time cure through its restoration of the parathyroid function and, therefore, could be the solution. A systematic literature review is conducted in the present paper, with the aim of outlining the possibilities of parathyroid allotransplantation and to calculate its efficacy. Additionally, various transpl...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
The American journal of medicine,
Volume 135, Issue 7, 14 2 2022, Pages 915-918
Effect of Alirocumab on Incidence of Atrial Fibrillation After Acute Coronary Syndromes: Insights from the ODYSSEY OUTCOMES Trial.
Lopes RD, Guimarães PO, Schwartz GG, Bhatt DL, Bittner VA, Budaj A, Dalby AJ, Diaz R, Goodman SG, Harrington RA, Jukema JW, Kiss RG, Loy M, Pordy R, Poulouin Y, Szarek M, White HD, Steg PG, ODYSSEY OUTCOMES Investigators
Background: Using data from the ODYSSEY OUTCOMES trial (NCT01663402), we sought to identify factors associated with the development of incident atrial fibrillation in patients with recent acute coronary syndrome without prior atrial fibrillation and to determine whether alirocumab treatment influenced risk of incident atrial fibrillation. Methods: ODYSSEY OUTCOMES compared alirocumab treatment with placebo in 18,924 patients with recent acute coronary syndrome and dyslipidemia despite high-inten...
Abstract
Cited 3 times since 2022 (0.9 per year)
source: EuropePMC
PLoS computational biology,
Volume 18, Issue 3, 14 2 2022, Pages e1009875
Does plasmid-based beta-lactam resistance increase E. coli infections: Modelling addition and replacement mechanisms.
Godijk NG, Bootsma MCJ, van Werkhoven HC, Schweitzer VA, de Greeff SC, Schoffelen AF, Bonten MJM
Infections caused by antibiotic-resistant bacteria have become more prevalent during past decades. Yet, it is unknown whether such infections occur in addition to infections with antibiotic-susceptible bacteria, thereby increasing the incidence of infections, or whether they replace such infections, leaving the total incidence unaffected. Observational longitudinal studies cannot separate both mechanisms. Using plasmid-based beta-lactam resistant E. coli as example we applied mathematical modell...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
European journal of nutrition,
Volume 61, Issue 5, 14 2 2022, Pages 2761-2773
Adherence to the Dutch healthy diet index and change in glycemic control and cardiometabolic markers in people with type 2 diabetes.
Bartels ECM, den Braver NR, Borgonjen-van den Berg KJ, Rutters F, van der Heijden A, Beulens JWJ
Purpose: To investigate whether adherence to the Dutch Healthy Diet index 2015 (DHD15-index) is associated with change in glycemic control and cardio-metabolic markers over two-year follow-up in people with type 2 diabetes (T2D). Methods: This prospective cohort study included 1202 individuals with T2D (mean age 68.7 ± 9.0 years; 62.5% male; mean HbA1c 53.8 ± 11.7 mmol/mol) from the Diabetes Care System cohort. Baseline dietary intake was assessed using a validated food frequency questionnaire,...
Abstract
Cited 22 times since 2022 (6.8 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 9, 11 2 2022, Pages 854314
Pirfenidone Has Anti-fibrotic Effects in a Tissue-Engineered Model of Human Cardiac Fibrosis.
Bracco Gartner TCL, Crnko S, Leiteris L, van Adrichem I, van Laake LW, Bouten CVC, Goumans MJ, Suyker WJL, Sluijter JPG, Hjortnaes J
A fundamental process in the development and progression of heart failure is fibrotic remodeling, characterized by excessive deposition of extracellular matrix proteins in response to injury. Currently, therapies that effectively target and reverse cardiac fibrosis are lacking, warranting novel therapeutic strategies and reliable methods to study their effect. Using a gelatin methacryloyl hydrogel, human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) and human fetal cardiac fibr...
Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 30, Issue 9, 11 2 2022, Pages 431-435
Emergency Heart failure Mortality Risk Grade may help to reduce heart failure admissions.
van Hattem NE, Beeres SLMA, Mertens BJA, Antoni ML, Atsma DE, Schalij MJ, den Haan MC
Introduction: Hospital admissions for heart failure (HF) are frequent and pose a heavy burden on health care resources. Currently, the decision to hospitalise is based on clinical judgement rather than on prognostic risk stratification. The Emergency Heart failure Mortality Risk Grade (EHMRG) was recently developed to identify high-risk HF patients in the emergency department (ED). Objective: To assess the ability of the EHMRG to predict 30-day mortality in Dutch HF patients visiting the ED and...
Abstract
Cited 11 times since 2022 (3.4 per year)
source: EuropePMC
Acta dermato-venereologica,
Volume 102, 11 2 2022, Pages adv00666
Identification of Risk Factors for Dupilumab-associated Ocular Surface Disease in Patients with Atopic Dermatitis.
Achten RE, Van Luijk C, Van der Rijst L, Bakker D, Spekhorst L, Zuithoff N, Schuttelaar M, Romeijn G, Voorberg A, Kamsteeg M, Haeck I, De Graaf M, Thijs J, De Boer J, De Bruin-Weller M
This study identified risk factors for the development of dupilumab-associated ocular surface disease in patients with moderate-to-severe atopic dermatitis in a large prospective daily practice cohort. Data from the Dutch BioDay Registry were used to assess the risk of developing dupilumab-associated ocular surface disease, by performing univariate and multivariate logistic regression analyses. A total of 469 patients were included, of which 152/469 (32.4%) developed dupilumab-associated ocular...
Abstract
Cited 2 times since 2022 (0.6 per year)
source: EuropePMC
Journal of child and adolescent psychiatric nursing : official publication of the Association of Child and Adolescent Psychiatric Nurses, Inc,
Volume 35, Issue 3, 10 2 2022, Pages 267-276
The relationship between posttraumatic stress disorder, posttraumatic growth, and rumination in adolescents after earthquake: A systematic review.
Turan N, Yılmaz DY, Ertekin K
Purpose: This systematic review aims to examine, from an interdisciplinary perspective, the relationship between posttraumatic stress disorder (PTSD), posttraumatic growth (PTG), and rumination in adolescents after an earthquake. The aim of the review is to provide high-quality, evidence-based recommendations that contribute to the roles of psychiatric nurses and the development of psychosocial support systems. Design and methods: This study has been conducted in line with the Centres for Review...
Abstract
Cited 1 times since 2022 (0.3 per year)
source: EuropePMC
Journal of lipid research,
Volume 63, Issue 5, 10 2 2022, Pages 100193
Apolipoprotein A-V is a potential target for treating coronary artery disease: evidence from genetic and metabolomic analyses.
Ibi D, Boot M, Dollé MET, Jukema JW, Rosendaal FR, Christodoulides C, Neville MJ, Koivula R, Rensen PCN, Karpe F, Noordam R, Willems van Dijk K
Triglyceride (TG)-lowering LPL variants in combination with genetic LDL-C-lowering variants are associated with reduced risk of coronary artery disease (CAD). Genetic variation in the APOA5 gene encoding apolipoprotein A-V also strongly affects TG levels, but the potential clinical impact and underlying mechanisms are yet to be resolved. Here, we aimed to study the effects of APOA5 genetic variation on CAD risk and plasma lipoproteins through factorial genetic association analyses. Using data fr...
Abstract
Cited 7 times since 2022 (2.2 per year)
source: EuropePMC
Emergent materials,
Volume 5, Issue 1, 9 2 2022, Pages 105-132
Nanotechnology in food and water security: on-site detection of agricultural pollutants through surface-enhanced Raman spectroscopy.
Yılmaz D, Günaydın BN, Yüce M
Agricultural pollutants are harmful components threatening human health, wildlife, the environment, and the ecosystem. To avoid their exposure, developing prevention and detection systems with high sensitivity and selectivity is required. Most conventional methods, including molecular and chromatographic techniques, cannot be adopted for outdoor on-site detection even though they can provide sensitive and selective detection. Thus, detection platforms that can provide on-site detection via minia...
Abstract
Cited 13 times since 2022 (4 per year)
source: EuropePMC
Diagnostics (Basel, Switzerland),
Volume 12, Issue 3, 9 2 2022, Pages 669
Sclerodermic Cardiomyopathy-A State-of-the-Art Review.
Giucă A, Gegenava T, Mihai CM, Jurcuţ C, Săftoiu A, Gȋrniţă DM, Popescu BA, Ajmone Marsan N, Jurcuț R
Systemic sclerosis (SSc) is a chronic autoimmune disorder with unknown triggering factors, and complex pathophysiologic links which lead to fibrosis of skin and internal organs, including the heart, lungs, and gut. However, more than 100 years after the first description of cardiac disease in SSc, sclerodermic cardiomyopathy (SScCmp) is an underrecognized, occult disease with important adverse long-term prognosis. Laboratory tests, electrocardiography (ECG) and cardiovascular multimodality imagi...
Abstract
Cited 9 times since 2022 (2.8 per year)
source: EuropePMC
Nature communications,
Volume 13, Issue 1, 9 2 2022, Pages 1222
Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus.
Stacey D, Chen L, Stanczyk PJ, Howson JMM, Mason AM, Burgess S, MacDonald S, Langdown J, McKinney H, Downes K, Farahi N, Peters JE, Basu S, Pankow JS, Tang W, Pankratz N, Sabater-Lleal M, de Vries PS, Smith NL, CHARGE Hemostasis Working Group, Gelinas AD, Schneider DJ, Janjic N, Samani NJ, Ye S, Summers C, Chilvers ER, Danesh J, Paul DS
Many individual genetic risk loci have been associated with multiple common human diseases. However, the molecular basis of this pleiotropy often remains unclear. We present an integrative approach to reveal the molecular mechanism underlying the PROCR locus, associated with lower coronary artery disease (CAD) risk but higher venous thromboembolism (VTE) risk. We identify PROCR-p.Ser219Gly as the likely causal variant at the locus and protein C as a causal factor. Using genetic analyses, human r...
Abstract
Cited 14 times since 2022 (4.3 per year)
source: EuropePMC
ESC heart failure,
Volume 9, Issue 3, 9 2 2022, Pages 1597-1607
Right ventricular-pulmonary artery coupling in cardiac resynchronization therapy: evolution and prognosis.
Stassen J, Galloo X, Hirasawa K, Chimed S, Marsan NA, Delgado V, van der Bijl P, Bax JJ
Aims: Chronic pressure overload and right ventricular (RV) dysfunction can lead to RV-pulmonary artery (PA) uncoupling in patients with heart failure. The evolution and prognostic values of RV-PA coupling assessed by echocardiography in patients undergoing cardiac resynchronization therapy (CRT) have not been thoroughly investigated. The aim of this study was to evaluate the evolution and prognostic value of tricuspid annular plane systolic excursion (TAPSE)/pulmonary artery systolic pressure (P...
Abstract
Cited 11 times since 2022 (3.4 per year)
source: EuropePMC
Frontiers in endocrinology,
Volume 13, 9 2 2022, Pages 845937
Dextroamphetamine Treatment in Children With Hypothalamic Obesity.
van Schaik J, Welling MS, de Groot CJ, van Eck JP, Juriaans A, Burghard M, Oude Ophuis SBJ, Bakker B, Tissing WJE, Schouten-van Meeteren AYN, van den Akker ELT, van Santen HM
Introduction: Hypothalamic obesity (HO) in children has severe health consequences. Lifestyle interventions are mostly insufficient and currently no drug treatment is approved for children with HO. Amphetamines are known for their stimulant side-effect on resting energy expenditure (REE) and suppressing of appetite. Earlier case series have shown positive effects of amphetamines on weight in children with acquired HO. We present our experiences with dextroamphetamine treatment in the, up to now,...
Abstract
Cited 4 times since 2022 (1.2 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 9, 7 1 2022, Pages 870390
Corrigendum: Robotic Cardiac Surgery in Europe: Status 2020.
Cerny S, Oosterlinck W, Onan B, Singh S, Segers P, Bolcal C, Alhan C, Navarra E, Pettinari M, Van Praet F, De Praetere H, Vojacek J, Cebotaru T, Modi P, Doguet F, Franke U, Ouda A, Melly L, Malapert G, Labrousse L, Gianoli M, Agnino A, Philipsen T, Jansens JL, Folliguet T, Palmen M, Pereda D, Musumeci F, Suwalski P, Cathenis K, Van den Eynde J, Bonatti J
[This corrects the article DOI: 10.3389/fcvm.2021.827515.].
Abstract
Cited 42 times since 2022 (13 per year)
source: EuropePMC
BMC geriatrics,
Volume 22, Issue 1, 5 1 2022, Pages 184
Age is the main determinant of COVID-19 related in-hospital mortality with minimal impact of pre-existing comorbidities, a retrospective cohort study.
Henkens MTHM, Raafs AG, Verdonschot JAJ, Linschoten M, van Smeden M, Wang P, van der Hooft BHM, Tieleman R, Janssen MLF, Ter Bekke RMA, Hazebroek MR, van der Horst ICC, Asselbergs FW, Magdelijns FJH, Heymans SRB, CAPACITY-COVID collaborative consortium
Background: Age and comorbidities increase COVID-19 related in-hospital mortality risk, but the extent by which comorbidities mediate the impact of age remains unknown. Methods: In this multicenter retrospective cohort study with data from 45 Dutch hospitals, 4806 proven COVID-19 patients hospitalized in Dutch hospitals (between February and July 2020) from the CAPACITY-COVID registry were included (age 69[58-77]years, 64% men). The primary outcome was defined as a combination of in-hospital mor...
Abstract
