6136 results
Cited 1 times since 2012 (0.1 per year)
source: EuropePMC
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis,
Volume 19, Issue 5, 3 1 2012, Pages 535-540
Long-term ongoing coagulopathy in premature infants with respiratory distress syndrome.
Buyukinan M, Yilmaz D, Yalaz M, Koroglu OA, Akisu M, Kavakli K, Kultursay N
The previously reported activated intravascular coagulation system in the acute phase of respiratory distress syndrome (RDS) has not been evaluated in the long term. We assessed the activities of coagulation system of a cohort of premature infants with RDS in comparison with healthy premature infants (HPIs), healthy mature infants (HMIs), and pediatric laboratory controls over a 6-month period. Cord and venous blood samples were taken at birth, at the first month and sixth month. Protein C (PC),...
Abstract
Cited 195 times since 2012 (15.2 per year)
source: EuropePMC
Basic research in cardiology,
Volume 107, Issue 4, 3 1 2012, Pages 270
Inhibition of RIP1-dependent necrosis prevents adverse cardiac remodeling after myocardial ischemia-reperfusion in vivo.
Oerlemans MI, Liu J, Arslan F, den Ouden K, van Middelaar BJ, Doevendans PA, Sluijter JP
Accumulating evidence indicates that programmed necrosis plays a critical role in cell death during ischemia-reperfusion. Necrostatin-1 (Nec-1), a small molecule capable of inhibiting a key regulator of programmed necrosis (RIP1), was shown to prevent necrotic cell death in experimental models including cardiac ischemia. However, no functional follow-up was performed and the action of Nec-1 remains unclear. Here, we studied whether Nec-1 inhibits RIP1-dependent necrosis and leads to long-term im...
Abstract
Cited 1 times since 2012 (0.1 per year)
source: EuropePMC
The pharmacogenomics journal,
Volume 13, Issue 4, 1 1 2012, Pages 318-324
Added value of pharmacogenetic testing in predicting statin response: results from the REGRESS trial.
van der Baan FH, Knol MJ, Maitland-van der Zee AH, Regieli JJ, van Iperen EP, Egberts AC, Klungel OH, Grobbee DE, Jukema JW
It was investigated whether pharmacogenetic factors, both as single polymorphism and as gene-gene interactions, have an added value over non-genetic factors in predicting statin response. Five common polymorphisms were selected in apolipoprotein E, angiotensin-converting enzyme, hepatic lipase and toll-like receptor 4. Linear regression models were built and compared on R(2) to estimate the added value of single polymorphisms and gene-gene interactions. The selected polymorphisms and the gene-ge...
Abstract
Cited 5 times since 2012 (0.4 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 20, Issue 5, 1 1 2012, Pages 197-201
Potential cardiovascular consequences of switching from atorvastatin to generic simvastatin in the Netherlands.
Liew D, Webb K, Meerding WJ, Buskens E, Jukema JW
Background: The statin authorisation form implemented in the Netherlands in January 2009 has led to significant switching of patients from atorvastatin to generic simvastatin, but often to less than equipotent doses. We sought to assess the potential consequences of this. Methods: A modelling analysis was undertaken using data from a pharmacy database covering the majority of drug prescriptions in the Netherlands. Recent meta-analyses provided data on the dose-specific, lipid-modifying potencies...
Abstract
Cited 22 times since 2012 (1.7 per year)
source: EuropePMC
Clinical science (London, England : 1979),
Volume 122, Issue 9, 1 1 2012, Pages 421-428
Activator protein-1 (AP-1) signalling in human atherosclerosis: results of a systematic evaluation and intervention study.
Meijer CA, Le Haen PA, van Dijk RA, Hira M, Hamming JF, van Bockel JH, Lindeman JH
Animal studies implicate the AP-1 (activator protein-1) pro-inflammatory pathway as a promising target in the treatment of atherosclerotic disease. It is, however, unclear whether these observations apply to human atherosclerosis. Therefore we evaluated the profile of AP-1 activation through histological analysis and tested the potential benefit of AP-1 inhibition in a clinical trial. AP-1 activation was quantified by phospho-c-Jun nuclear translocation (immunohistochemistry) on a biobank of aor...
Abstract
Cited 26 times since 2012 (2 per year)
source: EuropePMC
Pharmacogenomics,
Volume 13, Issue 7, 1 1 2012, Pages 831-840
Pharmacogenetics of statins: achievements, whole-genome analyses and future perspectives.
Postmus I, Verschuren JJ, de Craen AJ, Slagboom PE, Westendorp RG, Jukema JW, Trompet S
Statins are the most commonly prescribed class of drug worldwide and therapy is highly effective in reducing low-density lipoprotein cholesterol levels and cardiovascular events. However, there is large variability in clinical response to statin treatment. Recent research provides evidence that genetic variation contributes to this variable response to statin treatment. Until recently, pharmacogenetic studies have used mainly candidate gene approaches to investigate these effects. Since candidat...
Abstract
Cited 26 times since 2012 (2 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 98, Issue 9, 1 1 2012, Pages 743-754
Transcatheter aortic valve implantation: implications of multimodality imaging in patient selection, procedural guidance, and outcomes.
Delgado V, Kapadia S, Schalij MJ, Schuijf JD, Tuzcu EM, Bax JJ
Abstract
Cited 1 times since 2012 (0.1 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 20, Issue 5, 1 1 2012, Pages 240-244
Einthoven dissertation prizes 2011.
van der Wall EE, Schalij MJ, Umans V, van Gilst WH
Abstract
Journal of the American College of Cardiology,
Volume 59, Issue 21, 1 1 2012, Pages e41
Quadruple valve replacement: visualization with 256-slice computed tomography.
Symersky P, Budde RP, Koolbergen DR, de Mol BA
Abstract
Cited 10 times since 2012 (0.8 per year)
source: Scopus
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 20, Issue 5, 1 1 2012, Pages 202-207
Preexisting heart failure is an underestimated risk factor in cardiac surgery.
Kortekaas KA, Lindeman JH, Versteegh MI, Stijnen T, Dion RA, Klautz RJ
Background: Heart failure is characterised as a strong risk factor for systemic failure after cardiac surgery. However, the impact has never been substantiated. Methods: Patients with heart failure (n = 48) - scheduled for elective ventricular reconstruction or external constraint device-were compared with a one-to-one matched control group of patients without heart failure undergoing cardiac surgery between 2006 and 2009. Results: As expected, patients with heart failure more frequently experie...
Abstract
Cited 34 times since 2012 (2.6 per year)
source: EuropePMC
Archives of orthopaedic and trauma surgery,
Volume 132, Issue 8, 24 4 2012, Pages 1191-1197
Contralateral hip fractures and other osteoporosis-related fractures in hip fracture patients: incidence and risk factors. An observational cohort study of 1,229 patients.
Vochteloo AJ, Borger van der Burg BL, Röling MA, van Leeuwen DH, van den Berg P, Niggebrugge AH, de Vries MR, Tuinebreijer WE, Bloem RM, Nelissen RG, Pilot P
Purpose: To report risk factors, 1-year and overall risk for a contralateral hip and other osteoporosis-related fractures in a hip fracture population. Methods: An observational study on 1,229 consecutive patients of 50 years and older, who sustained a hip fracture between January 2005 and June 2009. Fractures were scored retrospectively for 2005-2008 and prospectively for 2008-2009. Rates of a contralateral hip and other osteoporosis-related fractures were compared between patients with and wit...
Abstract
Cited 14 times since 2012 (1.1 per year)
source: EuropePMC
International journal of cardiology,
Volume 167, Issue 4, 23 4 2012, Pages 1305-1310
Does left ventricular size impact on intrinsic right ventricular function in hypoplastic left heart syndrome?
Schlangen J, Fischer G, Steendijk P, Petko C, Scheewe J, Hart C, Hansen JH, Ahrend F, Rickers C, Kramer HH, Uebing A
Background: The size of the remnant left ventricle (LV) may influence right ventricular function and thus long-term outcome in palliated hypoplastic left heart syndrome (HLHS). We therefore sought to assess the impact of the size of the hypoplastic LV on intrinsic RV function in HLHS patients after Fontan surgery. Methods: Fifty-seven HLHS patients were studied 2.5 (range: 0.8-12.6) years after Fontan-type palliation with the pressure-volume conductance system. The patient cohort was divided int...
Abstract
Cited 18 times since 2012 (1.4 per year)
source: EuropePMC
Heart rhythm,
Volume 9, Issue 10, 20 3 2012, Pages 1605-1612
The mode of death in implantable cardioverter-defibrillator and cardiac resynchronization therapy with defibrillator patients: results from routine clinical practice.
Thijssen J, van Rees JB, Venlet J, Borleffs CJ, Höke U, Putter H, van der Velde ET, van Erven L, Schalij MJ
Background: Although data on the mode of death of implantable cardioverter-defibrillator (ICD) and cardiac resynchronization therapy with defibrillator (CRT-D) patients have been examined in randomized clinical trials, in routine clinical practice data are scarce. To provide reasonable expectations and prognosis for patients and physicians, this study assessed the mode of death in routine clinical practice. Objective: To assess the mode of death in ICD/CRT-D recipients in routine clinical practi...
Abstract
Interactive cardiovascular and thoracic surgery,
Volume 15, Issue 1, 19 3 2012, Pages 10-13
Surgical left ventricular radius enlargement by patch insertion on the beating heart: a new experimental aneurysm model.
Gründeman PF, van der Spoel TI, Steendijk P, van Slochteren F, Cramer MJ, Doevendans PA, Pasterkamp G
We presented a novel experimental aneurysm model for studies in left ventricular (LV) reconstruction techniques and assessed LV function. In eight pigs, the LV radius and geometry were enlarged surgically on the beating heart by inserting an aortic allograft construct. Haemodynamics and LV dimensions were assessed by echocardiography at baseline and under dobutamine stress. Surgery was successfully performed without lethal blood loss or arrhythmias. LV end-diastolic and end-systolic short-axis a...
Abstract
Cited 1 times since 2012 (0.1 per year)
source: EuropePMC
Congestive heart failure (Greenwich, Conn.),
Volume 18, Issue 4, 18 3 2012, Pages 198-204
Prognostic implications of left ventricular dilation in patients with nonischemic heart failure: interactions with restrictive filling pattern and mitral regurgitation.
Ghio S, Temporelli PL, Marsan NA, Poppe K, Giannuzzi P, Dini FL, Rossi A, Doughty RN, Whalley G, MeRGE HF collaborators
The aim of this study was to evaluate whether small left ventricular (LV) volumes increase the negative prognostic impact of a restrictive filling pattern (RFP) and that of mitral regurgitation (MR) in patients with nonischemic heart failure (HF). The Meta-analysis Research Group in Echocardiography (MeRGE) is a meta-analysis that collated individual patient data from several prospective echocardiography outcome studies. This analysis was restricted to 10 studies and 601 patients with nonischemi...
Abstract
Cited 14 times since 2012 (1.1 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 25, Issue 6, 17 3 2012, Pages 674-681
Right ventricular longitudinal peak systolic strain measurements from the subcostal view in patients with suspected pulmonary hypertension: a feasibility study.
Haeck ML, Scherptong RW, Antoni ML, Marsan NA, Vliegen HW, Holman ER, Schalij MJ, Bax JJ, Delgado V
Background: The assessment of right ventricular (RV) function with two-dimensional echocardiography can be challenging in patients with pulmonary hypertension, especially in those with chronic pulmonary disease. The aim of the present study was to evaluate the feasibility of measuring RV longitudinal peak systolic strain (LPSS) in the echocardiographic subcostal view in patients with suspected pulmonary hypertension. Methods: A total of 179 patients evaluated for pulmonary hypertension were incl...
Abstract
Cited 798 times since 2012 (61.8 per year)
source: EuropePMC
Nature genetics,
Volume 44, Issue 5, 15 3 2012, Pages 491-501
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Estrada K, Styrkarsdottir U, Evangelou E, Hsu YH, Duncan EL, Ntzani EE, Oei L, Albagha OM, Amin N, Kemp JP, Koller DL, Li G, Liu CT, Minster RL, Moayyeri A, Vandenput L, Willner D, Xiao SM, Yerges-Armstrong LM, Zheng HF, Alonso N, Eriksson J, Kammerer CM, Kaptoge SK, Leo PJ, Thorleifsson G, Wilson SG, Wilson JF, Aalto V, Alen M, Aragaki AK, Aspelund T, Center JR, Dailiana Z, Duggan DJ, Garcia M, Garcia-Giralt N, Giroux S, Hallmans G, Hocking LJ, Husted LB, Jameson KA, Khusainova R, Kim GS, Kooperberg C, Koromila T, Kruk M, Laaksonen M, Lacroix AZ, Lee SH, Leung PC, Lewis JR, Masi L, Mencej-Bedrac S, Nguyen TV, Nogues X, Nogues X, Patel MS, Prezelj J, Rose LM, Scollen S, Siggeirsdottir K, Smith AV, Svensson O, Trompet S, Trummer O, van Schoor NM, Woo J, Zhu K, Balcells S, Brandi ML, Buckley BM, Cheng S, Christiansen C, Cooper C, Dedoussis G, Ford I, Frost M, Goltzman D, González-Macías J, Kähönen M, Karlsson M, Khusnutdinova E, Koh JM, Kollia P, Langdahl BL, Leslie WD, Lips P, Ljunggren Ö, Lorenc RS, Marc J, M
Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 genome-wide association studies and 32,961 individuals of European and east Asian ancestry. We tested the top BMD-associated markers for replication in 50,933 independent subjects and for association with risk of low-trauma fracture in 31,016 individuals with a history of fracture (cases) and 102,444 controls. We identifi...
Abstract
Cited 6 times since 2012 (0.5 per year)
source: EuropePMC
Antonie van Leeuwenhoek,
Volume 102, Issue 2, 10 2 2012, Pages 401-406
In vivo analysis of Saccharomyces cerevisiae plasma membrane ATPase Pma1p isoforms with increased in vitro H+/ATP stoichiometry.
de Kok S, Yilmaz D, Daran JM, Pronk JT, van Maris AJ
Plasma membrane H(+)-ATPase isoforms with increased H(+)/ATP ratios represent a desirable asset in yeast metabolic engineering. In vivo proton coupling of two previously reported Pma1p isoforms (Ser800Ala, Glu803Gln) with increased in vitro H(+)/ATP stoichiometries was analysed by measuring biomass yields of anaerobic maltose-limited chemostat cultures expressing only the different PMA1 alleles. In vivo H(+)/ATP stoichiometries of wildtype Pma1p and the two isoforms did not differ significantly.
Abstract
Cited 18 times since 2012 (1.4 per year)
source: EuropePMC
Injury,
Volume 43, Issue 7, 6 1 2012, Pages 1107-1111
Below-elbow cast for metaphyseal both-bone fractures of the distal forearm in children: a randomised multicentre study.
Colaris JW, Biter LU, Allema JH, Bloem RM, van de Ven CP, de Vries MR, Kerver AJ, Reijman M, Verhaar JA
Introduction: Minimally displaced metaphyseal both-bone fractures of the distal forearm in children are often treated with an above-elbow cast (AEC). Treatment with a below-elbow cast (BEC) could give more comfort, but might lead to fracture displacement reducing pronation and supination. Because this has not been systematically investigated, we set up a randomised multicentre study. The purpose of this study was to find out whether BEC causes equal limitation of pronation and supination but wit...
Abstract
Cited 6 times since 2012 (0.5 per year)
source: EuropePMC
The Netherlands journal of medicine,
Volume 70, Issue 3, 1 1 2012, Pages 155
Valproic acid-induced DRESS syndrome with acute liver failure.
van Zoelen MA, de Graaf M, van Dijk MR, Bogte A, van Erpecum KJ, Rockmann H, Maarschalk-Ellerbroek LJ
Abstract
