Research

Publications

Below you can find a list of our published research.

9618 results

Cited 5 times since 2022 (1.6 per year) source: EuropePMC

Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Volume 377, Issue 1859, 25 4 2022, Pages 20210106 Social tolerance and interactional opportunities as drivers of gestural redoings in orang-utans. Fröhlich M, van Schaik CP

Communicative repair is a fundamental and universal element of interactive language use. It has been suggested that the persistence and elaboration after communicative breakdown in nonhuman primates constitute two evolutionary building blocks of this capacity, but the conditions favouring it are poorly understood. Because zoo-housed individuals of some species are more social and more terrestrial than in the wild, they should be more likely to show gestural redoings (i.e. both repetition and ela... Abstract

Cited 4 times since 2022 (1.3 per year) source: EuropePMC

Current heart failure reports, Volume 19, Issue 5, 25 4 2022, Pages 255-266 Change of Heart: the Epitranscriptome of Small Non-coding RNAs in Heart Failure. Woudenberg T, Kruyt ND, Quax PHA, Nossent AY

Purpose of review: Small non-coding RNAs regulate gene expression and are highly implicated in heart failure. Recently, an additional level of post-transcriptional regulation has been identified, referred to as the epitranscriptome, which encompasses the body of post-transcriptional modifications that are placed on RNA molecules. In this review, we summarize the current knowledge on the small non-coding RNA epitranscriptome in heart failure. Recent findings: With the rise of new methods to study... Abstract

Cited 25 times since 2022 (8.1 per year) source: EuropePMC

Alimentary pharmacology & therapeutics, Volume 56, Issue 6, 23 4 2022, Pages 1044-1054 Real-world experience of switching from intravenous to subcutaneous vedolizumab maintenance treatment for inflammatory bowel diseases. Volkers A, Straatmijer T, Duijvestein M, Sales A, Levran A, van Schaik F, Maljaars J, Gecse K, Ponsioen C, Grootjans J, Hanzel J, Tack G, Jansen J, Hoentjen F, de Boer N, van der Marel S, Dijkstra G, Oldenburg B, Löwenberg M, van der Meulen A, D Haens G, IBD center Amsterdam and the Dutch Initiative on Crohn and Colitis

Background: Subcutaneous (SC) vedolizumab is effective in inflammatory bowel diseases (IBD) when administered after induction with two infusions. Aim: To assess the effectiveness, safety and pharmacokinetics of a switch from intravenous (IV) to SC maintenance vedolizumab in patients with IBD METHODS: In this prospective cohort study, patients with IBD who had ≥4 months IV vedolizumab were switched to SC vedolizumab. We studied the time to discontinuation of SC vedolizumab, adverse events (AEs),... Abstract

Cited 4 times since 2022 (1.3 per year) source: EuropePMC

Archives of psychiatric nursing, Volume 41, 23 4 2022, Pages 96-102 Examination of individuals' depression, anxiety, and stress levels during the COVID-19 pandemic in Turkey. Erdoğan S, Can AA, Abiç A, Yilmaz DV

Purpose: This research was conducted to determine the depression, anxiety, and stress levels of individuals during the COVID-19 epidemic. In addition, the compatibility of the Depression-Anxiety-Stress Scale (DASS-21) scale results with the participants' feeling depressed, anxious, and stressed were examined. Design and methods: The sample of the study consisted of 870 individuals over the age of 18 between May-August 2021. The data of the study were collected online, using the personal inf... Abstract

Cited 7 times since 2022 (2.3 per year) source: EuropePMC

Endocrine connections, Volume 11, Issue 8, 21 3 2022, Pages e220276 Resting energy expenditure in children at risk of hypothalamic dysfunction. Van Schaik J, Burghard M, Lequin MH, van Maren EA, van Dijk AM, Takken T, Rehorst-Kleinlugtenbelt LB, Bakker B, Meijer L, Hoving EW, Fiocco M, Schouten-van Meeteren AYN, Tissing WJE, van Santen HM

Objective: Children with suprasellar brain damage are at risk of hypothalamic dysfunction (HD). HD may lead to decreased resting energy expenditure (REE). Decreased REE, however, is not present in all children with HD. Our aim was to assess which children suspect for HD have low REE, and its association with clinical severity of HD or radiological hypothalamic damage. Patients and methods: A retrospective cohort study was performed. Measured REE (mREE) of children at risk of HD was compared to p... Abstract

Cited 6 times since 2022 (1.9 per year) source: EuropePMC

The Annals of thoracic surgery, Volume 115, Issue 6, 21 3 2022, Pages 1396-1402 The Aortic Root in Acute Type A Dissection: Repair or Replace? Arabkhani B, Verhoef J, Tomšič A, van Brakel TJ, Hjortnaes J, Klautz RJM

Background: The effect of an "aggressive" approach on the aortic root in acute type A aortic dissection (ATAAD) remains insufficiently explored. Methods: Retrospective analysis was conducted between 1992 and 2020 of a single-center, prospective cohort of consecutive patients aged ≥18 years diagnosed with ATAAD. Patients were divided into 2 groups: aortic root replacement (ARR; prosthetic or valve-sparing root replacement, n = 141) and conservative root approach (CRA; root sparing of pa... Abstract

Cited 9 times since 2022 (2.9 per year) source: EuropePMC

International journal of cardiology. Heart & vasculature, Volume 42, 19 3 2022, Pages 101086 Dyspnea in patients with atrial fibrillation: Mechanisms, assessment and an interdisciplinary and integrated care approach. van der Velden RMJ, Hermans ANL, Pluymaekers NAHA, Gawalko M, Elliott A, Hendriks JM, Franssen FME, Slats AM, van Empel VPM, Van Gelder IC, Thijssen DHJ, Eijsvogels TMH, Leue C, Crijns HJGM, Linz D, Simons SO

Atrial fibrillation (AF) is the most common sustained heart rhythm disorder and is often associated with symptoms that can significantly impact quality of life and daily functioning. Palpitations are the cardinal symptom of AF and many AF therapies are targeted towards relieving this symptom. However, up to two-third of patients also complain of dyspnea as a predominant self-reported symptom. In clinical practice it is often challenging to ascertain whether dyspnea represents an AF-related sympt... Abstract

Cited 2 times since 2022 (0.6 per year) source: EuropePMC

Urologie (Heidelberg, Germany), Volume 61, Issue 12, 19 3 2022, Pages 1365-1372 [Acceptance and status of digitalization in clinics and practices : Current assessment in German urology]. Borkowetz A, Leitsmann M, Baunacke M, Borgmann H, Boehm K, Groeben C, Roigas J, Schneider AW, Speck T, Schroeder-Printzen I, Zillich S, Volkmer B, Witzsch U, Huber J, Arbeitskreis Versorgungsforschung, Qualität und Ökonomie der Deutschen Gesellschaft für Urologie e V, Arbeitskreis Informationstechnologie und Dokumentation der Deutschen Gesellschaft für Urologie e V

Background: Digitalization of patient documentation and introduction of the electronic patient record (ePA) pose challenges to everyday clinical practice. Objectives: We investigated the acceptance and status of the digitalization of patient data and the introduction of the ePA among German urologists. Materials and methods: A questionnaire with 30 questions about the acceptance and status of digitalization of patient documentation and ePA was sent out via the newsletter of the German Society of... Abstract

Cited 6 times since 2022 (1.9 per year) source: EuropePMC

JMIR formative research, Volume 6, Issue 7, 19 3 2022, Pages e37278 A Web-Based Stress Management Intervention for University Students in Indonesia (Rileks): Feasibility Study Using a Pretest-Posttest Design. Juniar D, van Ballegooijen W, Schulte M, van Schaik A, Passchier J, Heber E, Lehr D, Sadarjoen SS, Riper H

Background: University students are susceptible to excessive stress. A web-based stress management intervention holds promise to improve stress but is still at a novel stage in Indonesia. Objective: The aim of this paper was to report the feasibility of the intervention we developed-Rileks-among university students in Indonesia in terms of acceptability and usability, and to propose recommendations for future improvements. Methods: A single-group pretest and posttest design was used. Participant... Abstract

Cited 1 times since 2022 (0.3 per year) source: EuropePMC

The international journal of cardiovascular imaging, Volume 38, Issue 12, 19 3 2022, Pages 2771-2779 Left ventricular assist device and pump thrombosis: the importance of the inflow cannula position. Kortekaas KA, de Graaf MA, Palmen M, Braun J, Mertens BJA, Tops LF, Beeres SLMA

Pump thrombosis is a devastating complication after left ventricular assist device implantation. This study aims to elucidate the relation between left ventricular assist device implantation angle and risk of pump thrombosis. Between November 2010 and March 2020, 53 left ventricular assist device-patients underwent a computed tomography scan. Using a 3-dimensional multiplanar reformation the left ventricular axis was reconstructed to measure the implantation angle of the inflow cannula. All pati... Abstract

Cited 10 times since 2022 (3.2 per year) source: EuropePMC

Journal of the European Academy of Dermatology and Venereology : JEADV, Volume 36, Issue 11, 19 3 2022, Pages 2153-2165 Systemic treatment of children and adolescents with atopic dermatitis aged ≥2 years: a Delphi consensus project mapping expert opinion in Northern Europe. de Graaf M, Janmohamed SR, Schuttelaar MLA, Agner T, Alfonso JH, De Schepper S, Deleuran M, Despontin K, Elenius V, Ghislain PD, Huilaja L, Johansson EK, Kvenshagen BK, Mandelin JM, Olset H, Svensson A, van Tuyll van Serooskerken AM, Thyssen JP, Vestergaard C

Background: Paediatric atopic dermatitis (AD) can be burdensome, affecting mental health and impairing quality of life for children and caregivers. Comprehensive guidelines exist for managing paediatric AD, but practical guidance on using systemic therapy is limited, particularly for new therapies including biologics and Janus kinase (JAK) inhibitors, recently approved for various ages in this indication. Objectives: This expert consensus aimed to provide practical recommendations within this ad... Abstract

Cited 3 times since 2022 (1 per year) source: EuropePMC

The international journal of cardiovascular imaging, Volume 38, Issue 12, 18 3 2022, Pages 2687-2693 Prognostic value of left atrial volume index in degenerative mitral stenosis. Yedidya I, Butcher SC, Stassen J, van der Bijl P, Ngiam JN, Chew NWS, Sia CH, Leow R, Li TY, Kong WKF, Poh KK, Kornowski R, Marsan NA, Delgado V, Bax JJ

Purpose: Degenerative mitral stenosis (DMS) is associated with a poor prognosis. Although mean transmitral gradient (TMG) has shown a good correlation with outcome, little is known about the association between other echocardiographic parameters and prognosis in patients with DMS. The current study aimed to evaluate the prognostic value of left atrial volume index (LAVI) in patients with DMS. Methods: A total of 155 patients with DMS (72[63-80] years, 67% female) were included. The population wa... Abstract

Cited 3 times since 2022 (1 per year) source: EuropePMC

Journal of cardiovascular development and disease, Volume 9, Issue 7, 18 3 2022, Pages 230 Left Atrial Remodeling after Mitral Valve Repair for Primary Mitral Regurgitation: Evolution over Time and Prognostic Significance. Stassen J, van Wijngaarden AL, Wu HW, Palmen M, Tomsic A, Delgado V, Bax JJ, Marsan NA

Left atrial (LA) dilatation is associated with worse outcomes in primary mitral regurgitation (MR). However, the effects of mitral valve repair on LA size and its prognostic implications are not well known. In the current study, LA volume index (LAVi) and LA reservoir strain (LASr) were evaluated immediately before and after surgery, and during long-term follow-up in 226 patients undergoing mitral valve repair for primary MR (age 62 ± 13 years, 66% male). Mean LAVi was reduced significantly afte... Abstract

Herzschrittmachertherapie & Elektrophysiologie, Volume 33, Issue 3, 16 3 2022, Pages 261-267 Imaging for risk stratification of sudden cardiac death. van der Bijl P, Bax JJ

Sudden cardiac death (SCD) can be effectively prevented with the use of implantable cardioverter-defibrillator (ICD). Current guidelines advocate an ICD for primary prevention in the presence of an left ventricular ejection fraction (LVEF) ≤ 35%. The majority of individuals that experience SCD, however, have an LVEF > 35%. Multimodality cardiac imaging has the ability to visualize the three factors responsible for arrhythmia-mediated SCD, namely substrate, trigger and modulator. Advances in c... Abstract

The European physical journal. C, Particles and fields, Volume 82, Issue 7, 16 3 2022, Pages 618 Scintillation light detection in the 6-m drift-length ProtoDUNE Dual Phase liquid argon TPC. Abud AA, Abi B, Acciarri R, Acero MA, Adames MR, Adamov G, Adamowski M, Adams D, Adinolfi M, Aduszkiewicz A, Aguilar J, Ahmad Z, Ahmed J, Aimard B, Ali-Mohammadzadeh B, Alion T, Allison K, Monsalve SA, AlRashed M, Alt C, Alton A, Alvarez R, Amedo P, Anderson J, Andreopoulos C, Andreotti M, Andrews M, Andrianala F, Andringa S, Anfimov N, Ankowski A, Antoniassi M, Antonova M, Antoshkin A, Antusch S, Aranda-Fernandez A, Arellano L, Arnold LO, Arroyave MA, Asaadi J, Asquith L, Aurisano A, Aushev V, Autiero D, Lara VA, Ayala-Torres M, Azfar F, Back A, Back H, Back JJ, Backhouse C, Bagaturia I, Bagby L, Balashov N, Balasubramanian S, Baldi P, Baller B, Bambah B, Barao F, Barenboim G, Alzas PB, Barker G, Barkhouse W, Barnes C, Barr G, Monarca JB, Barros A, Barros N, Barrow JL, Basharina-Freshville A, Bashyal A, Basque V, Batchelor C, Chagas EBD, Battat JBR, Battisti F, Bay F, Bazetto MCQ, Alba JLLB, Beacom JF, Bechetoille E, Behera B, Beigbeder C, Bellantoni L, Bellettini G, Bellini V, Beltramello O, Benekos N, Mont

DUNE is a dual-site experiment for long-baseline neutrino oscillation studies, neutrino astrophysics and nucleon decay searches. ProtoDUNE Dual Phase (DP) is a 6 × 6 × 6 m 3 liquid argon time-projection-chamber (LArTPC) that recorded cosmic-muon data at the CERN Neutrino Platform in 2019-2020 as a prototype of the DUNE Far Detector. Charged particles propagating through the LArTPC produce ionization and scintillation light. The scintillation light signal in these detectors can provide the tr... Abstract

Cited 5 times since 2022 (1.6 per year) source: EuropePMC

Breast cancer research and treatment, Volume 195, Issue 1, 16 3 2022, Pages 65-74 Factors affecting inter-individual variability in endoxifen concentrations in patients with breast cancer: results from the prospective TOTAM trial. Braal CL, Westenberg JD, Buijs SM, Abrams S, Mulder TAM, van Schaik RHN, Koolen SLW, Jager A, Mathijssen RHJ

Introduction: Endoxifen-the principal metabolite of tamoxifen-is subject to a high inter-individual variability in serum concentration. Numerous attempts have been made to explain this, but thus far only with limited success. By applying predictive modeling, we aimed to identify factors that determine the inter-individual variability. Our purpose was to develop a prediction model for endoxifen concentrations, as a strategy to individualize tamoxifen treatment by model-informed dosing in order to... Abstract

Cited 2 times since 2022 (0.6 per year) source: EuropePMC

The American journal of cardiology, Volume 179, 15 3 2022, Pages 64-69 Effects of Left Bundle Branch Block and Pacemaker Implantation on Left Ventricular Systolic Function After Transcatheter Aortic Valve Implantation. Dolci G, Singh GK, Wang X, van der Kley F, de Weger A, Bootsma M, Ajmone Marsan N, Bax JJ, Delgado V

Permanent pacemaker implantation (PPI) and left bundle branch block (LBBB) frequency after transcatheter aortic valve implantation (TAVI) and their effect on left ventricular ejection fraction (LVEF) remain controversial. We evaluated the incidence of PPI and new-onset LBBB after TAVI and their impact on LVEF at 6-month follow-up. Moreover, the impact of right ventricular (RV) pacing burden on changes in LVEF after TAVI was analyzed. The electrocardiograms of 377 patients (age 80 ± 7 years, 52%... Abstract

Cited 6 times since 2022 (1.9 per year) source: EuropePMC

Antimicrobial resistance and infection control, Volume 11, Issue 1, 15 3 2022, Pages 98 Duration of rectal colonization with extended-spectrum beta-lactamase-producing Escherichia coli: results of an open, dynamic cohort study in Dutch nursing home residents (2013-2019). Weterings V, van den Bijllaardt W, Bootsma M, Hendriks Y, Kilsdonk L, Mulders A, Kluytmans J

Background: In 2016, a study in a Dutch nursing home showed prolonged colonization duration of extended-spectrum β-lactamase-producing (ESBL)-ST131 compared to ESBL-non-ST131. In this study, we assessed the duration of rectal ESBL-producing E. coli (ESBL-EC) colonization in residents in the same nursing home for an extended period of six years. We aimed to estimate the influence of a possible bias when follow up is started during an outbreak. Methods: Between 2013 and 2019, repetitive point prev... Abstract

Cited 1 times since 2022 (0.3 per year) source: EuropePMC

Journal of neuroimmunology, Volume 370, 14 2 2022, Pages 577932 Longitudinal analysis of anti-drug antibody development in multiple sclerosis patients treated with interferon beta-1a (Rebif™) using B cell receptor repertoire analysis. van der Weele L, Pollastro S, van Schaik BDC, van Kampen AHC, Niewold ITG, Kuijpers TW, Warnke C, Jensen PEH, Kramer D, Ryner M, Hermanrud C, Dönnes P, Pallardy M, Spindeldreher S, Deisenhammer F, Fogdell-Hahn A, de Vries N, ABIRISK Consortium

A significant proportion of multiple sclerosis (MS) patients treated with interferon beta-1a (Rebif™) develop anti-drug antibodies (ADA) with a negative impact on treatment efficacy. We hypothesized that high-throughput B-cell receptor (BCR) repertoire analysis could be used to predict and monitor ADA development. To study this we analyzed 228 peripheral blood samples from 68 longitudinally followed patients starting on interferon beta-1a. Our results show that whole blood BCR analysis does not... Abstract

Cited 1 times since 2022 (0.3 per year) source: EuropePMC

International journal of pediatric otorhinolaryngology, Volume 160, 14 2 2022, Pages 111240 Treatment of choanal atresia in a cohort of 29 patients: Determinants for success or failure. van Schaik CGR, Paasch S, Albrecht T, Becker S

Background: Choanal Atresia is a congenital condition that presents as a blockage from the nasal cavity to the nasopharynx. According to the German statistical Institute (Statistisches Bundesamt), the incidence in Germany in 2018 reached 2.74 in 10,000 live births. It can present unilaterally or bilaterally. As newborns are obligate nasal breathers, management of bilateral atresia has to be performed early after birth. As for unilateral atresia, the optimal age for treatment was determined to be... Abstract