Research

Publications

Below you can find a list of our published research.

8892 results

Cited 6 times since 2022 (1.7 per year) source: EuropePMC

Philosophical transactions of the Royal Society of London. Series B, Biological sciences, Volume 377, Issue 1851, 4 1 2022, Pages 20210150 Male services during between-group conflict: the 'hired gun' hypothesis revisited. Bshary R, Richter XL, van Schaik C

In many group-living mammals, philopatric females form the stable core of the group and defend food or shelter against other groups of females. Where males are larger, their participation could give their female group the edge. How can females secure the contribution of males that are neither the father of current infants, nor the dominant male expecting to sire the next generation of infants? It has been proposed that females recruit these males as 'hired guns', receiving social suppo... Abstract

Diabetes care, Volume 45, Issue 4, 1 1 2022, Pages e82-e83 Response to Comment on Dawed et al. Genome-Wide Meta-analysis Identifies Genetic Variants Associated With Glycemic Response to Sulfonylureas. Diabetes Care 2021;44:2673-2682. Dawed AY, Yee SW, Zhou K, van Leeuwen N, Zhang Y, Siddiqui MK, Etheridge A, Innocenti F, Xu F, Li JH, Beulens JW, van der Heijden AA, Slieker RC, Chang YC, Mercader JM, Kaur V, Witte JS, Lee MTM, Kamatani Y, Momozawa Y, Kubo M, Palmer CNA, Florez JC, Hedderson MM, 't Hart LM, Giacomini KM, Pearson ER, for MetGen Plus, for the DIRECT Consortium

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Cited 4 times since 2022 (1.1 per year) source: EuropePMC

Proceedings of the National Academy of Sciences of the United States of America, Volume 119, Issue 14, 1 1 2022, Pages e2112886119 Phenotype-Based Threat Assessment. Yang J, Eslami M, Chen YP, Das M, Zhang D, Chen S, Roberts AJ, Weston M, Volkova A, Faghihi K, Moore RK, Alaniz RC, Wattam AR, Dickerman A, Cucinell C, Kendziorski J, Coburn S, Paterson H, Obanor O, Maples J, Servetas S, Dootz J, Qin QM, Samuel JE, Han A, van Schaik EJ, de Figueiredo P

Bacterial pathogen identification, which is critical for human health, has historically relied on culturing organisms from clinical specimens. More recently, the application of machine learning (ML) to whole-genome sequences (WGSs) has facilitated pathogen identification. However, relying solely on genetic information to identify emerging or new pathogens is fundamentally constrained, especially if novel virulence factors exist. In addition, even WGSs with ML pipelines are unable to discern phen... Abstract

Cited 2 times since 2022 (0.6 per year) source: EuropePMC

European heart journal. Cardiovascular Imaging, Volume 23, Issue 5, 1 1 2022, Pages 590-597 EACVI survey on hypertrophic cardiomyopathy. Podlesnikar T, Cardim N, Ajmone Marsan N, D'Andrea A, Cameli M, Popescu BA, Schulz-Menger J, Stankovic I, Toplisek J, Maurer G, Haugaa KH, Dweck MR

Aims: The European Association of Cardiovascular Imaging (EACVI) Scientific Initiatives Committee performed a global survey to evaluate current practice for the assessment and management of patients with hypertrophic cardiomyopathy (HCM). Methods and results: A total of 213 centres from 38 different countries (87% European) responded to the survey. One hundred twenty-one (57%) centres followed HCM patients in a general cardiology outpatient clinic and 85 (40%) centres in a specialized HCM/cardio... Abstract

Cited 29 times since 2022 (8.2 per year) source: EuropePMC

The lancet. Diabetes & endocrinology, Volume 10, Issue 5, 1 1 2022, Pages 330-340 Metabolic risk factors and effect of alirocumab on cardiovascular events after acute coronary syndrome: a post-hoc analysis of the ODYSSEY OUTCOMES randomised controlled trial. Ostadal P, Steg PG, Poulouin Y, Bhatt DL, Bittner VA, Chua T, Diaz R, Goodman SG, Huo Y, Jukema JW, Karpov Y, Pordy R, Scemama M, Szarek M, White HD, Schwartz GG, ODYSSEY OUTCOMES Investigators

Background: Many patients with acute coronary syndrome have concurrent metabolic risk factors that affect risk of major adverse cardiovascular events (MACE). We aimed to assess the effects of the PCSK9 inhibitor alirocumab compared with placebo on MACE according to baseline metabolic risk factors. Methods: We performed a post-hoc analysis of the ODYSSEY OUTCOMES trial, which was a multicentre, double-blind, randomised controlled trial done in 1315 hospitals and outpatient clinics in 57 countries... Abstract

Cited 14 times since 2022 (3.9 per year) source: EuropePMC

European heart journal. Cardiovascular Imaging, Volume 23, Issue 5, 1 1 2022, Pages 699-707 Prognostic implications of left ventricular myocardial work index in patients with ST-segment elevation myocardial infarction and reduced left ventricular ejection fraction. Butcher SC, Lustosa RP, Abou R, Marsan NA, Bax JJ, Delgado V

Aims: This study aimed to determine whether lower values of left ventricular (LV) global work index (GWI) at baseline were associated with a reduction in LV functional recovery and poorer long-term prognosis in patients with reduced LV ejection fraction (LVEF ≤40%) following ST-segment elevation myocardial infarction (STEMI). Methods and results: A total of 197 individuals (62 ± 12 years, 75% male) with STEMI treated with primary percutaneous coronary intervention and reduced LVEF were evaluated... Abstract

Cited 3 times since 2022 (0.8 per year) source: EuropePMC

The American journal of cardiology, Volume 173, 1 1 2022, Pages 48-55 Meta-Analysis of Bilateral Versus Single Internal Thoracic Artery Grafting in Patients ≥70 Years of Age. Mulder BS, Candura D, Schoones JW, Etnel JRG, Schouten GN, de Weger A, Tomšič A, Klautz RJM

The optimal choice of graft material in patients ≥70 years of age undergoing coronary artery bypass grafting remains unknown. A systematic review of literature was conducted by searching PubMed, Embase, Web of Science, and Cochrane Library databases for original publications that compared bilateral internal thoracic artery (BITA) grafting with single internal thoracic artery grafting in patients ≥70 years of age. Data were extracted by 2 independent investigators and meta-analyzed with the use o... Abstract

Cited 22 times since 2022 (6.2 per year) source: EuropePMC

The American journal of cardiology, Volume 173, 1 1 2022, Pages 120-127 Prognostic Implications of Right Ventricular Systolic Dysfunction in Cardiac Amyloidosis. Tjahjadi C, Fortuni F, Stassen J, Debonnaire P, Lustosa RP, Marsan NA, Delgado V, Bax JJ

Left ventricular (LV) systolic dysfunction in cardiac amyloidosis (CA) is associated with poor prognosis. This study aimed to investigate the prognostic implications of right ventricular (RV) systolic dysfunction in CA. A total of 93 patients diagnosed with CA who underwent standard and speckle-tracking echocardiography were included. During a median follow-up of 17 (5 to 38) months, 42 patients (45%) died. Nonsurvivors were more likely to present with immunoglobulin light-chain amyloidosis and... Abstract

Cited 3 times since 2022 (0.8 per year) source: EuropePMC

JACC. Cardiovascular interventions, Volume 15, Issue 8, 1 1 2022, Pages 901 The Ratio Fallacy of Prosthesis-Patient Mismatch. Velders BJJ, Vriesendorp MD, Herrmann HC, Klautz RJM

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Cited 4 times since 2022 (1.1 per year) source: EuropePMC

BMJ open, Volume 12, Issue 4, 1 1 2022, Pages e051658 Effectiveness and cost-effectiveness of surgery versus casting for elderly patients with Displaced intra-Articular type C distal Radius fractures: protocol of a randomised controlled Trial with economic evaluation (the DART study). Ter Meulen DP, Mulders MAM, Kruiswijk AA, Kret EJ, Slichter ME, van Dongen JM, Kerkhoffs GMMJ, Goslings JC, Kleinlugtenbelt YV, Willigenburg NW, Schep NWL, Poolman RW, DART Study Group

Introduction: Current literature is inconclusive about the optimal treatment of elderly patients with displaced intra-articular distal radius fractures. Cast treatment is less invasive and less expensive than surgical treatment. Nevertheless, surgery is often the preferred treatment for this common type of distal radius fracture. Patients with a non-acceptable position after closed reduction are more likely to benefit from surgery than patients with an acceptable position after closed reduction.... Abstract

Cited 4 times since 2022 (1.1 per year) source: EuropePMC

Current health sciences journal, Volume 48, Issue 2, 1 1 2022, Pages 169-175 Determining Covid-19 Vaccine Literacy Levels of Nursing Students. Yilmaz D, Yilmaz DU, Yönt GH

This study aimed to determine nursing students' levels of COVID-19 vaccine literacy and the affecting variables. This descriptive research was carried out on 391 students receiving education at Bursa Uludağ University Nursing Department between January and March 2022. Research data were collected using a "Student Introduction Form" and the "COVID-19 Vaccine Literacy Scale". The mean total score of the nursing students included in the study on the COVID-19 Vaccine Literac... Abstract

Cited 1 times since 2022 (0.3 per year) source: EuropePMC

The Journal of clinical endocrinology and metabolism, Volume 107, Issue 5, 1 1 2022, Pages e2213-e2214 Response to Letter to the Editor From Behar-Cohen et al.: The Cortisol Response of Male and Female Choroidal Endothelial Cells: Implications for Central Serous Chorioretinopathy. Brinks J, van Dijk EHC, Notenboom RGE, Quax PHA, Boon CJF, Meijer OC

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Cited 5 times since 2022 (1.4 per year) source: EuropePMC

Nature microbiology, Volume 7, Issue 4, 1 1 2022, Pages 482-483 Baas Becking meets One Health. van Schaik W

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Nature cardiovascular research, Volume 1, Issue 4, 1 1 2022, Pages 289-290 R-SMAD in control of the R-smooth muscle cell. Goumans MJ, Quax PHA

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Cited 21 times since 2022 (5.9 per year) source: EuropePMC

European heart journal, Volume 43, Issue 16, 1 1 2022, Pages 1554-1565 Alirocumab after acute coronary syndrome in patients with a history of heart failure. White HD, Schwartz GG, Szarek M, Bhatt DL, Bittner VA, Chiang CE, Diaz R, Goodman SG, Jukema JW, Loy M, Pagidipati N, Pordy R, Ristić AD, Zeiher AM, Wojdyla DM, Steg PG, ODYSSEY OUTCOMES Investigators

Aims: Patients with heart failure (HF) have not been shown to benefit from statins. In a post hoc analysis, we evaluated outcomes in ODYSSEY OUTCOMES in patients with vs. without a history of HF randomized to the proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor alirocumab or placebo. Methods and results: Among 18 924 patients with recent acute coronary syndrome (ACS) receiving intensive or maximum-tolerated statin treatment, the primary outcome of major adverse cardiovascular even... Abstract

Cited 2 times since 2022 (0.6 per year) source: EuropePMC

European journal of radiology open, Volume 9, 31 5 2022, Pages 100417 Correlation between quantification of myocardial area at risk and ischemic burden at cardiac computed tomography. van Driest FY, Bijns CM, van der Geest RJ, Broersen A, Dijkstra J, Jukema JW, Scholte AJHA

Purpose: This study aims to investigate the correlation between myocardial area at risk at coronary computed tomography angiography (CCTA) and the ischemic burden derived from myocardial computed tomography perfusion (CTP) by using the 17-segment model. Methods: Forty-two patients with chest pain complaints who underwent a combined CCTA and CTP protocol were identified. Patients with reversible ischemia at CTP and at least one stenosis of ≥ 50% at CCTA were selected. Myocardial area at risk was... Abstract

JACC. Cardiovascular interventions, Volume 15, Issue 8, 30 5 2022, Pages e95-e97 "Level Crossroads": A Venous Graft Compressing a Left Internal Mammary Graft Presenting as Myocardial Infarction. Bingen BO, Amri IA, Scherptong RWC, Montero Cabezas JM

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Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 30, Issue 1, 30 5 2022, Pages 321-323 Application of a deep learning algorithm to calcium scoring in myocardial perfusion imaging. van der Bijl P, Stassen J, Bax JJ

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Cited 24 times since 2022 (6.7 per year) source: EuropePMC

ESC heart failure, Volume 9, Issue 3, 30 5 2022, Pages 2007-2012 The first experience with sodium-glucose cotransporter 2 inhibitor for the treatment of systemic right ventricular failure. Egorova AD, Nederend M, Tops LF, Vliegen HW, Jongbloed MRM, Kiès P

In congenitally corrected transposition of the great arteries, the morphological right ventricle supports the systemic circulation. This chronic exposure to pressure overload ultimately leads to systemic right ventricular (sRV) dysfunction and heart failure. Pharmacological options for the treatment of sRV failure are poorly defined and no solid recommendations are made in the most recent guidelines. Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are a new class of antihyperglycaemic drugs t... Abstract

Cited 5 times since 2022 (1.4 per year) source: EuropePMC

European heart journal open, Volume 2, Issue 3, 29 5 2022, Pages oeac022 Determinants of label non-adherence to non-vitamin K oral anticoagulants in patients with newly diagnosed atrial fibrillation. Seelig J, Trinks-Roerdink EM, Chu G, Pisters R, Theunissen LJHJ, Trines SA, Pos L, Kirchhof CJHJ, de Jong SFAMS, den Hartog FR, van Alem AP, Polak PE, Tieleman RG, van der Voort PH, Lenderink T, Otten AM, de Jong JSSG, Gu YL, Luermans JGLM, Kruip MJHA, Timmer SAJ, de Vries TAC, Cate HT, Geersing GJ, Rutten FH, Huisman MV, Hemels MEW

Aims: To evaluate the extent and determinants of off-label non-vitamin K oral anticoagulant (NOAC) dosing in newly diagnosed Dutch AF patients. Methods and results: In the DUTCH-AF registry, patients with newly diagnosed AF ( Abstract