6173 results
Cited 46 times since 2004 (2.2 per year)
source: EuropePMC
Circulation,
Volume 110, Issue 16, 11 2 2004, Pages 2383-2388
Opposite patterns of left ventricular remodeling after coronary revascularization in patients with ischemic cardiomyopathy: role of myocardial viability.
Rizzello V, Poldermans D, Boersma E, Biagini E, Schinkel AF, Krenning B, Elhendy A, Vourvouri EC, Sozzi FB, Maat A, Crea F, Roelandt JR, Bax JJ
Background: In patients with ischemic cardiomyopathy, left ventricular (LV) remodeling is an important prognostic indicator. The precise relation between viable myocardium, revascularization, and ongoing or reversed remodeling is unknown and was evaluated in the present study. Methods and results: A total of 100 patients with ischemic cardiomyopathy underwent dobutamine stress echocardiography to assess myocardial viability and LV geometry (volumes and shape). At a mean of 10.2 months and 4.5 ye...
Abstract
Cited 8 times since 2004 (0.4 per year)
source: EuropePMC
Alcohol and alcoholism (Oxford, Oxfordshire),
Volume 39, Issue 6, 11 2 2004, Pages 499-502
Oral chronic ethanol administration to rodents by agar gel diet.
Bykov I, Palmén M, Piirainen L, Lindros KO
Background: Chronic ethanol administration to rodents requires specially designed equipment and is labor intensive. Here we report a new procedure. Method: A commercial liquid diet preparation was made into a gel by addition of 0.5% agar. The gel, containing 5.3% ethanol, was offered in Falcon tubes equipped with a feeding opening. Results: The gel consumption by C57/Bl mice resulted in high blood ethanol levels (average 43 mM). After 6 weeks, marked liver steatosis and significantly increased s...
Abstract
Cited 59 times since 2004 (2.9 per year)
source: EuropePMC
Arteriosclerosis, thrombosis, and vascular biology,
Volume 24, Issue 12, 7 1 2004, Pages 2313-2319
Overexpression of IL-18 decreases intimal collagen content and promotes a vulnerable plaque phenotype in apolipoprotein-E-deficient mice.
de Nooijer R, von der Thüsen JH, Verkleij CJ, Kuiper J, Jukema JW, van der Wall EE, van Berkel JC, Biessen EA
Objective: Although IL-18 has been implicated in atherosclerotic lesion development, little is known about its role in advanced atherosclerotic plaques. This study aims to assess the effect of IL-18 overexpression on the stability of preexisting plaques. Methods and results: Atherosclerotic lesions were elicited in carotid arteries of apolipoprotein E (apoE)-deficient mice (n=32) by placement of a perivascular collar. Overexpression of IL-18 was effected by intravenous injection of an adenoviral...
Abstract
Cited 5 times since 2004 (0.2 per year)
source: EuropePMC
The American journal of cardiology,
Volume 94, Issue 7, 1 1 2004, Pages 954-957
Prognostic stratification of patients with right bundle branch block using dobutamine stress echocardiography.
Biagini E, Schinkel AF, Rizzello V, van Domburg RT, Pedone C, Elhendy A, Krenning BJ, Bountioukos M, Vourvouri EC, Branzi A, Rapezzi C, Simoons ML, Bax JJ, Poldermans D
The presence of a right bundle branch block (RBBB) is associated with increased mortality. We studied the role of dobutamine stress echocardiography for the prognostic stratification of patients with RBBB. The presence of an abnormal dobutamine stress echocardiography was the strongest predictor of cardiac events and provided incremental prognostic information to clinical and stress test data.
Abstract
Cited 3 times since 2004 (0.1 per year)
source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
Volume 45, Issue 10, 1 1 2004, Pages 1605-1610
Functional changes after partial left ventriculectomy and mitral valve repair assessed by gated perfusion SPECT.
Schäfers M, Stypmann J, Wilhelm MJ, Stegger L, Kies P, Hermann S, Schmidt C, Breithardt G, Scheld HH, Schober O
Unlabelled: A myocardial remodeling in dilated cardiomyopathy (DCM) after partial left ventriculectomy (PLV) has been previously discussed. The aim of this study was to investigate the functional changes in the follow-up of patients with DCM undergoing PLV using electrocardiographically triggered perfusion SPECT (gated SPECT). Methods: Twelve DCM patients (10 men, 2 women; 56 +/- 9 y [mean +/- SD]), after successful PLV and mitral valve repair (PLV-MVR), were monitored by gated SPECT and echocar...
Abstract
Cited 14 times since 2004 (0.7 per year)
source: EuropePMC
Pediatrics international : official journal of the Japan Pediatric Society,
Volume 46, Issue 5, 1 1 2004, Pages 621-623
Septic pulmonary emboli presenting with deep venous thrombosis secondary to acute osteomyelitis.
Yüksel H, Ozgüven AA, Akil I, Ergüder I, Yilmaz D, Cabuk M
Abstract
Cited 19 times since 2004 (0.9 per year)
source: EuropePMC
The Laryngoscope,
Volume 114, Issue 10, 1 1 2004, Pages 1775-1779
Effects of ascorbic acid on oxidative system and transient evoked otoacoustic emissions in rabbits exposed to noise.
Dereköy FS, Köken T, Yilmaz D, Kahraman A, Altuntaş A
Objectives/hypothesis: The objective was to investigate the effects of both noise exposure and ascorbic acid on oxidative status and hearing thresholds of rabbits. Study design: Randomized prospective animal study comparing oxidative parameters and otoacoustic emissions in two rabbit groups exposed to noise. One group was given ascorbic acid, the other group was not given any treatment. Methods: Two groups of rabbits were used in the study; each group had six rabbits. The six rabbits in the firs...
Abstract
Cited 6 times since 2004 (0.3 per year)
source: EuropePMC
Cardiovascular research,
Volume 64, Issue 1, 1 1 2004, Pages 9-11
Heart failure with preserved ejection fraction. Diastolic dysfunction, subtle systolic dysfunction, systolic-ventricular and arterial stiffening, or misdiagnosis?
Steendijk P
Abstract
Cited 219 times since 2004 (10.6 per year)
source: EuropePMC
Circulation,
Volume 110, Issue 14, 27 4 2004, Pages 2010-2016
Magnetic resonance imaging analysis of right ventricular pressure-volume loops: in vivo validation and clinical application in patients with pulmonary hypertension.
Kuehne T, Yilmaz S, Steendijk P, Moore P, Groenink M, Saaed M, Weber O, Higgins CB, Ewert P, Fleck E, Nagel E, Schulze-Neick I, Lange P
Background: The aims of this study were to validate MRI-derived right ventricular (RV) pressure-volume loops for assessment of RV myocardial contractility and then to apply this technique in patients with chronic RV pressure overload for assessment of myocardial contractility, ventricular pump function, and VA coupling. Methods and results: Flow-directed catheters were guided under MR fluoroscopy (1.5 T) into the RV for invasive pressure measurements. Simultaneously, ventricular volumes and myoc...
Abstract
The Annals of thoracic surgery,
Volume 78, Issue 3, 1 1 2004, Pages e58-60
Median sternotomy for reoperation of the distal aortic arch in postcoarctectomy patients.
Vriend JW, Mulder BJ, Schoof PH, Hazekamp MG
We report the usefulness of a median sternotomy approach for the surgical treatment of residual aortic gradients or recoarctation and aortic aneurysms. This series confirms that excellent surgical results can be obtained in this technically challenging group of patients needing postcoarctation repair.
Abstract
Cited 9 times since 2004 (0.4 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 11, Issue 5, 1 1 2004, Pages 527-533
Incidence and predictors of heart failure during long-term follow-up after stress Tc-99m sestamibi tomography in patients with suspected coronary artery disease.
Elhendy A, Schinkel AF, van Domburg RT, Bax JJ, Poldermans D
Background: Heart failure is a major cause of morbidity and death in patients with coronary artery disease (CAD). The aim of this study was to define the incidence and predictors of heart failure during long-term follow-up in patients with suspected CAD referred for stress myocardial perfusion imaging. Methods and results: We studied 787 patients (mean age, 57 +/- 12 years; 470 men) with suspected CAD who had no history of previous myocardial infarction or heart failure with exercise (n = 508) o...
Abstract
Cited 75 times since 2004 (3.6 per year)
source: EuropePMC
Circulation,
Volume 110, Issue 11 Suppl 1, 1 1 2004, Pages II18-22
Extensive left ventricular remodeling does not allow viable myocardium to improve in left ventricular ejection fraction after revascularization and is associated with worse long-term prognosis.
Bax JJ, Schinkel AF, Boersma E, Elhendy A, Rizzello V, Maat A, Roelandt JR, van der Wall EE, Poldermans D
Background: Extensive left ventricular (LV) remodeling may not allow functional recovery after revascularization, despite the presence of viable myocardium. Methods and results: Seventy-nine consecutive patients with ischemic cardiomyopathy (left ventricle ejection fraction [LVEF] 29+/-7%) underwent surgical revascularization. Before revascularization, viability was assessed by metabolic imaging with F18-fluorodeoxyglucose and SPECT. LV volumes and LVEF were assessed by resting echocardiography....
Abstract
Cited 4 times since 2004 (0.2 per year)
source: EuropePMC
The American journal of cardiology,
Volume 94, Issue 6, 1 1 2004, Pages 757-760
Comparison of long-term effect of coronary artery bypass grafting in patients with ischemic cardiomyopathy with viable versus nonviable left ventricular myocardium.
Rizzello V, Poldermans D, Biagini E, Kertai MD, Schinkel AF, Boersma E, Krenning B, Vourvouri EC, Bountioukos M, Crea F, Roelandt JR, Bax JJ
In this study, 63% of patients with a substantial amount of viable myocardium showed an increased left ventricular ejection fraction (LVEF) 12 +/- 3 months after coronary artery bypass grafting. In 93% of these patients, increased LVEF persisted at 4.5 +/- 1 years of follow-up. Conversely, in nonviable patients, LVEF did not increase at 12 +/- 3 months or at follow-up of 4.5 +/- 1 years.
Abstract
Cited 15 times since 2004 (0.7 per year)
source: EuropePMC
The American journal of cardiology,
Volume 94, Issue 6, 1 1 2004, Pages 733-739
Prognostic value of dobutamine stress echocardiography in patients with systemic hypertension and known or suspected coronary artery disease.
Sozzi FB, Elhendy A, Rizzello V, van Domburg RT, Kertai M, Vourvouri E, Schinkel AF, Bax JJ, Roelandt JR, Poldermans D
Currently, there are no outcome data to suggest an incremental value of stress echocardiography in the risk stratification of patients who have hypertension after controlling for the left ventricular mass index (LVMI). This study assessed the incremental value of dobutamine stress echocardiography (DSE) for the prediction of mortality rate and cardiac events in patients who have hypertension. We studied 596 patients who had hypertension (mean age 62 +/- 12 years; 382 men) and who underwent DSE f...
Abstract
Cited 42 times since 2004 (2 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 44, Issue 5, 1 1 2004, Pages 1113-1123
Fibroblast growth factor-1 improves cardiac functional recovery and enhances cell survival after ischemia and reperfusion: a fibroblast growth factor receptor, protein kinase C, and tyrosine kinase-dependent mechanism.
Palmen M, Daemen MJ, De Windt LJ, Willems J, Dassen WR, Heeneman S, Zimmermann R, Van Bilsen M, Doevendans PA
Objectives: We sought to investigate the role of fibroblast growth factor (FGF)-1 during acute myocardial ischemia and reperfusion. Background: The FGFs display cardioprotective effects during ischemia and reperfusion. Methods: We investigated FGF-1-induced cardioprotection during ischemia and reperfusion and the intracellular signaling pathways responsible for these effects in an ex vivo murine setup of myocardial ischemia and reperfusion. Results: Cardiac-specific human FGF-1 overexpression wa...
Abstract
Cited 20 times since 2004 (1 per year)
source: EuropePMC
Clinical science (London, England : 1979),
Volume 107, Issue 3, 1 1 2004, Pages 255-261
An integrated evaluation of endothelial constitutive nitric oxide synthase polymorphisms and coronary artery disease in men.
Agema WR, de Maat MP, Zwinderman AH, Kastelein JJ, Rabelink TJ, van Boven AJ, Feskens EJ, Boer JM, van der Wall EE, Jukema JW
In the present study, we sought to evaluate the role of three polymorphisms in the ecNOS (endothelial constitutive nitric oxide synthase) gene in relation to the existence, severity and progression of CAD (coronary artery disease), MI (myocardial infarction) and the occurrence of ischaemia in a predominantly Caucasian population. Patients with CAD (n = 760) and age- and sex-matched population-based controls (n = 691) were genotyped for the -786T/C, E/D298 and 4a/b polymorphisms. Patients were ra...
Abstract
Cited 3 times since 2004 (0.1 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 90, Issue 9, 1 1 2004, Pages 1035
Aortic arch aneurysm.
Bogaard K, Scholte AJ
Abstract
Cited 130 times since 2004 (6.3 per year)
source: EuropePMC
Circulation,
Volume 110, Issue 11 Suppl 1, 1 1 2004, Pages II103-8
Restrictive annuloplasty and coronary revascularization in ischemic mitral regurgitation results in reverse left ventricular remodeling.
Bax JJ, Braun J, Somer ST, Klautz R, Holman ER, Versteegh MI, Boersma E, Schalij MJ, van der Wall EE, Dion RA
Background: Data on combined coronary artery bypass grafting (CABG) and restrictive annuloplasty in patients with ischemic cardiomyopathy are scarce, and the effect on reverse left ventricular (LV) remodeling is unknown. Methods and results: 51 patients with ischemic LV dysfunction (LV ejection fraction 31+/-8%) and severe mitral regurgitation (grade 3 to 4+) underwent CABG and restrictive annuloplasty with stringent downsizing of the mitral annulus (by 2 sizes, Physio-ring, mean size 28+/-2). S...
Abstract
Cited 137 times since 2004 (6.6 per year)
source: EuropePMC
Circulation,
Volume 110, Issue 11, 30 5 2004, Pages 1418-1423
Plasma levels of cholesteryl ester transfer protein and the risk of future coronary artery disease in apparently healthy men and women: the prospective EPIC (European Prospective Investigation into Cancer and nutrition)-Norfolk population study.
Boekholdt SM, Kuivenhoven JA, Wareham NJ, Peters RJ, Jukema JW, Luben R, Bingham SA, Day NE, Kastelein JJ, Khaw KT
Background: Low plasma levels of cholesteryl ester transfer protein (CETP) are associated with elevated levels of HDL cholesterol (HDL-C), but it remains unclear whether this translates into a concomitant reduction in the risk of coronary artery disease (CAD). Evidence exists that the effect of CETP depends on metabolic context, in particular on triglyceride levels. Methods and results: A nested case-control study was performed in the prospective EPIC-Norfolk cohort study. Cases were apparently...
Abstract
Cited 13 times since 2004 (0.6 per year)
source: EuropePMC
Nederlands tijdschrift voor geneeskunde,
Volume 148, Issue 33, 1 1 2004, Pages 1646-1647
[National registry and DNA-bank of patients with congenital heart disease: the CONCOR-project].
Vriend JW, van der Velde ET, Mulder BJ
Although survival of patients with congenital heart disease has dramatically improved since surgical repair has become available, cure is seldom achieved. Exact data on long-term outcome are not available, however, because a national registry is lacking. Furthermore, little is known about the role of genetic defects in the development of congenital heart disease. The CONCOR-project (CONgenital CORvitia) has been set up to facilitate the investigation of the long-term outcome and molecular basis...
Abstract
