9618 results
Cited 90 times since 2009 (5.5 per year)
source: EuropePMC
Clinical pharmacology and therapeutics,
Volume 86, Issue 3, 3 1 2009, Pages 319-327
UGT1A9 -275T>A/-2152C>T polymorphisms correlate with low MPA exposure and acute rejection in MMF/tacrolimus-treated kidney transplant patients.
van Schaik RH, van Agteren M, de Fijter JW, Hartmann A, Schmidt J, Budde K, Kuypers D, Le Meur Y, van der Werf M, Mamelok R, van Gelder T
Mycophenolate mofetil (MMF) is an immunosuppressive drug commonly used in the context of kidney transplantation. Exposure to the active metabolite mycophenolic acid (MPA) is associated with risk of allograft rejection. MPA pharmacokinetics varies between individuals, the potential cause being the presence of genetic polymorphisms in key enzymes. We genotyped 338 kidney transplant patients for UGT1A8, UGT1A9, UGT2B7, and MRP2 polymorphisms and recorded MPA exposure and biopsy-proven acute rejecti...
Abstract
Cited 20 times since 2009 (1.2 per year)
source: EuropePMC
Circulation. Arrhythmia and electrophysiology,
Volume 2, Issue 3, 3 1 2009, Pages 242-248
Long-term outcome of ablative therapy of postoperative supraventricular tachycardias in patients with univentricular heart: a European multicenter study.
de Groot NM, Lukac P, Blom NA, van Kuijk JP, Pedersen AK, Hansen PS, Delacretaz E, Schalij MJ
Background: Catheter ablation has evolved as a possible curative treatment modality for supraventricular tachycardias (SVT) in patients with univentricular heart. However, the long-term outcome of ablation procedures is unknown. We evaluated the procedural and long-term outcome of ablative therapy of late postoperative SVT in patients with univentricular heart. Methods and results: Patients with univentricular heart (n=19, 11 male; age, 29+/-9 years) referred for ablation of SVT were studied. Ab...
Abstract
Cited 32 times since 2009 (2 per year)
source: EuropePMC
European heart journal,
Volume 30, Issue 13, 2 1 2009, Pages 1621-1626
Recurrence of ventricular arrhythmias in ischaemic secondary prevention implantable cardioverter defibrillator recipients: long-term follow-up of the Leiden out-of-hospital cardiac arrest study (LOHCAT).
Borleffs CJ, van Erven L, Schotman M, Boersma E, Kiès P, van der Burg AE, Zeppenfeld K, Bootsma M, van der Wall EE, Bax JJ, Schalij MJ
Aims: To assess the long-term rate of mortality and the recurrence of potentially life-threatening ventricular arrhythmias in secondary prevention implantable cardioverter defibrillator (ICD) patients and to construct a model for baseline risk stratification. Methods and results: Since 1996, all patients with ischaemic heart disease, receiving ICD therapy for secondary prevention of sudden death, were included in the current study. Patients were evaluated at implantation and during long-term fol...
Abstract
Cited 19 times since 2009 (1.2 per year)
source: EuropePMC
Comparative medicine,
Volume 59, Issue 3, 1 1 2009, Pages 280-286
Comparison of 3 methods to induce acute pulmonary hypertension in pigs.
Roehl AB, Steendijk P, Baumert JH, Schnoor J, Rossaint R, Hein M
Large animal models for acute pulmonary hypertension (PHT) show distinct differences between species and underlying mechanisms. Two embolic procedures and continuous infusion of a stable thromboxane A(2) analogue (U46619) were explored for their ability to induce PHT and their effects on right ventricular function and pulmonary and systemic circulation in 9 pigs. Injection of small (100 to 200 microm) or large (355 to 425 microm) polystyrene beads and incremental dosage (0.2 to 0.8 microg kg(-1)...
Abstract
Cited 5 times since 2009 (0.3 per year)
source: EuropePMC
Coronary artery disease,
Volume 20, Issue 4, 1 1 2009, Pages 281-287
Head-to-head comparison between bicycle exercise testing and coronary calcium score and coronary stenoses on multislice computed tomography.
Pundziute G, Schuijf JD, van Werkhoven JM, Nucifora G, van der Wall EE, Wouter Jukema J, Bax JJ
Objective: To perform a head-to-head comparison between signs of ischemia during bicycle exercise testing and coronary atherosclerosis on multislice computed tomography (MSCT) in patients with suspected coronary artery disease (CAD). Methods: Two hundred and one patients underwent exercise testing, followed by 64-slice MSCT. A subgroup of 63 (31%) patients also underwent conventional coronary angiography. The exercise test was positive or negative based on electrocardiographic signs of ischemia....
Abstract
Cited 158 times since 2009 (9.7 per year)
source: EuropePMC
Annals of surgery,
Volume 249, Issue 6, 1 1 2009, Pages 921-926
Bisoprolol and fluvastatin for the reduction of perioperative cardiac mortality and myocardial infarction in intermediate-risk patients undergoing noncardiovascular surgery: a randomized controlled trial (DECREASE-IV).
Dunkelgrun M, Boersma E, Schouten O, Koopman-van Gemert AW, van Poorten F, Bax JJ, Thomson IR, Poldermans D, Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group
Objective: This study evaluated the effectiveness and safety of beta-blockers and statins for the prevention of perioperative cardiovascular events in intermediate-risk patients undergoing noncardiovascular surgery. Summary background data: Beta-blockers and statins reduce perioperative cardiac events in high-risk patients undergoing vascular surgery by restoring the myocardial oxygen supply/demand balance and/or stabilizing coronary plaques. However, their effects in intermediate-risk patients...
Abstract
Current problems in cardiology,
Volume 34, Issue 6, 1 1 2009, Pages 277-295
Classic images: Cardiac computed tomography.
Schuijf JD, Kroft LJ, de Roos A, Bax JJ
Cardiac computed tomography (CT) has evolved into a valuable clinical tool for cardiac evaluation. Cardiac CT is increasingly used for imaging of the coronary arteries for the evaluation of (suspected) coronary artery disease, but many other cardiac structures may be the topic for CT investigation. This article reviews general indications for cardiac CT imaging. Common variants and pathologies of the cardiovascular system are illustrated by clinical examples.
Abstract
Cited 20 times since 2009 (1.2 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 22, Issue 6, 1 1 2009, Pages 688-694
Changes in global left ventricular function by multidirectional strain assessment in heart failure patients undergoing cardiac resynchronization therapy.
Delgado V, Ypenburg C, Zhang Q, Mollema SA, Fung JW, Schalij MJ, Yu CM, Bax JJ
Background: The aim of this study was to evaluate the acute and late effects of cardiac resynchronization therapy (CRT) on multidirectional left ventricular (LV) strain assessed by two-dimensional speckle-tracking imaging and automated function imaging (AFI). Methods: Multidirectional LV strain (global radial strain [GRS Avg], global circumferential strain [GCS Avg], and global longitudinal peak systolic strain [GLPSS Avg]) were measured in 141 patients with heart failure before CRT implantation...
Abstract
Cited 78 times since 2009 (4.8 per year)
source: EuropePMC
Journal of the peripheral nervous system : JPNS,
Volume 14, Issue 2, 1 1 2009, Pages 93-100
Subcutaneous immunoglobulin therapy for multifocal motor neuropathy.
Eftimov F, Vermeulen M, de Haan RJ, van den Berg LH, van Schaik IN
The objective of this study was to investigate whether subcutaneous immunoglobulin (SCIg) treatment is feasible and safe in maintaining muscle strength of patients with multifocal motor neuropathy (MMN). Patients fulfilling the EFNS/PNS criteria for definite MMN treated with intravenous immunoglobulin (IVIg) were switched to weekly SCIg in a single-center, open-label pilot intervention study. The first group of patients started with a SCIg dose equivalent to 50% of the IVIg maintenance dose. In...
Abstract
Cited 4 times since 2009 (0.2 per year)
source: EuropePMC
Neural computation,
Volume 21, Issue 6, 1 1 2009, Pages 1554-1588
A first-order nonhomogeneous Markov model for the response of spiking neurons stimulated by small phase-continuous signals.
Tapson J, Jin C, van Schaik A, Etienne-Cummings R
We present a first-order nonhomogeneous Markov model for the interspike-interval density of a continuously stimulated spiking neuron. The model allows the conditional interspike-interval density and the stationary interspike-interval density to be expressed as products of two separate functions, one of which describes only the neuron characteristics and the other of which describes only the signal characteristics. The approximation shows particularly clearly that signal autocorrelations and cros...
Abstract
Journal of paediatrics and child health,
Volume 45, Issue 6, 1 1 2009, Pages 391-392
Arachnoid cyst and costovertebral defects in Aicardi syndrome.
Yüksel D, Yilmaz D, Usak E, Senbil N, Gürer Y
Abstract
Cited 10 times since 2009 (0.6 per year)
source: EuropePMC
IEEE transactions on ultrasonics, ferroelectrics, and frequency control,
Volume 56, Issue 6, 1 1 2009, Pages 1199-1206
Contrast agent response to chirp reversal: simulations, optical observations, and acoustical verification.
Novell A, van der Meer S, Versluis M, de Jong N, Bouakaz A
Active response of a microbubble is characterized by its resonance behavior where the microbubble might oscillate after the excitation waveform has been turned off. We investigate in this paper an excitation approach based on this resonance phenomenon using chirps. The technique, called chirp reversal, consists in transmitting a first excitation signal, the up-sweep chirp (UPF) of increasing frequency with time, and a second excitation signal, the down-sweep (DNF) that is a replica of the first...
Abstract
Cited 29 times since 2009 (1.8 per year)
source: EuropePMC
Diabetes care,
Volume 32, Issue 8, 1 1 2009, Pages 1507-1512
Differences in atherosclerotic plaque burden and morphology between type 1 and 2 diabetes as assessed by multislice computed tomography.
Djaberi R, Schuijf JD, Boersma E, Kroft LJ, Pereira AM, Romijn JA, Scholte AJ, Jukema JW, Bax JJ
OBJECTIVE It is unclear whether the coronary atherosclerotic plaque burden is similar in patients with type 1 and type 2 diabetes. By using multislice computed tomography (MSCT), the presence, degree, and morphology of coronary artery disease (CAD) in patients with type 1 and type 2 diabetes were compared. RESEARCH DESIGN AND METHODS Prospectively, coronary artery calcium (CAC) scoring and MSCT coronary angiography were performed in 135 asymptomatic patients (65 patients with type 1 diabetes and...
Abstract
Cited 8 times since 2009 (0.5 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 17, Issue 6, 1 1 2009, Pages 262-264
A genome wide association analysis in the GENDER study.
Sampietro ML, Pons D, de Knijff P, Slagboom PE, Zwinderman A, Jukema JW
Percutaneous coronary intervention (PCI) has become an effective therapy to treat coronary artery diseases. However, one of the major drawbacks of PCI is the occurrence of restenosis in 8 to 40% of all treated patients. The GENetic Determinants of Restenosis (GENDER) project was designed to study the association between genetic polymorphisims and clinical restenosis. The discovery of genetic variants associated to the occurrence of restenosis after PCI may provide a more tailored therapy and may...
Abstract
Cited 355 times since 2009 (21.9 per year)
source: EuropePMC
Heart rhythm,
Volume 6, Issue 6, 1 1 2009, Pages 886-933
EHRA/HRS Expert Consensus on Catheter Ablation of Ventricular Arrhythmias: developed in a partnership with the European Heart Rhythm Association (EHRA), a Registered Branch of the European Society of Cardiology (ESC), and the Heart Rhythm Society (HRS); in collaboration with the American College of Cardiology (ACC) and the American Heart Association (AHA).
Aliot EM, Stevenson WG, Almendral-Garrote JM, Bogun F, Calkins CH, Delacretaz E, Della Bella P, Hindricks G, Jaïs P, Josephson ME, Kautzner J, Kay GN, Kuck KH, Lerman BB, Marchlinski F, Reddy V, Schalij MJ, Schilling R, Soejima K, Wilber D, European Heart Rhythm Association (EHRA), Registered Branch of the European Society of Cardiology (ESC), Heart Rhythm Society (HRS), American College of Cardiology (ACC), American Heart Association (AHA)
Abstract
Cited 2 times since 2009 (0.1 per year)
source: EuropePMC
European heart journal,
Volume 30, Issue 13, 31 5 2009, Pages 1554-1555
Towards assessment of left ventricular mechanics in true three dimensions.
Delgado V, Bax JJ, van der Wall EE
Abstract
Cited 61 times since 2009 (3.8 per year)
source: EuropePMC
Basic research in cardiology,
Volume 104, Issue 5, 26 4 2009, Pages 485-498
Coronary microvascular resistance: methods for its quantification in humans.
Knaapen P, Camici PG, Marques KM, Nijveldt R, Bax JJ, Westerhof N, Götte MJ, Jerosch-Herold M, Schelbert HR, Lammertsma AA, van Rossum AC
Coronary microvascular dysfunction is a topic that has recently gained considerable interest in the medical community owing to the growing awareness that microvascular dysfunction occurs in a number of myocardial disease states and has important prognostic implications. With this growing awareness, comes the desire to accurately assess the functional capacity of the coronary microcirculation for diagnostic purposes as well as to monitor the effects of therapeutic interventions that are targeted...
Abstract
The international journal of cardiovascular imaging,
Volume 25, Issue 6, 26 4 2009, Pages 643-645
Cardiac magnetic resonance imaging in primary PCI: additional value?
van der Wall EE, Bax JJ, Jukema JW, Schalij MJ
Abstract
Cited 1688 times since 2009 (103.9 per year)
source: EuropePMC
Science (New York, N.Y.),
Volume 325, Issue 5937, 22 4 2009, Pages 197-201
Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans.
Garten RJ, Davis CT, Russell CA, Shu B, Lindstrom S, Balish A, Sessions WM, Xu X, Skepner E, Deyde V, Okomo-Adhiambo M, Gubareva L, Barnes J, Smith CB, Emery SL, Hillman MJ, Rivailler P, Smagala J, de Graaf M, Burke DF, Fouchier RA, Pappas C, Alpuche-Aranda CM, López-Gatell H, Olivera H, López I, Myers CA, Faix D, Blair PJ, Yu C, Keene KM, Dotson PD, Boxrud D, Sambol AR, Abid SH, St George K, Bannerman T, Moore AL, Stringer DJ, Blevins P, Demmler-Harrison GJ, Ginsberg M, Kriner P, Waterman S, Smole S, Guevara HF, Belongia EA, Clark PA, Beatrice ST, Donis R, Katz J, Finelli L, Bridges CB, Shaw M, Jernigan DB, Uyeki TM, Smith DJ, Klimov AI, Cox NJ
Since its identification in April 2009, an A(H1N1) virus containing a unique combination of gene segments from both North American and Eurasian swine lineages has continued to circulate in humans. The lack of similarity between the 2009 A(H1N1) virus and its nearest relatives indicates that its gene segments have been circulating undetected for an extended period. Its low genetic diversity suggests that the introduction into humans was a single event or multiple events of similar viruses. Molecu...
Abstract
Cited 25 times since 2009 (1.5 per year)
source: EuropePMC
European heart journal,
Volume 30, Issue 13, 22 4 2009, Pages 1559-1564
The current status of interventions aiming at reducing sudden cardiac death in dialysis patients.
de Bie MK, van Dam B, Gaasbeek A, van Buren M, van Erven L, Bax JJ, Schalij MJ, Rabelink TJ, Jukema JW
Mortality in dialysis patients is extremely high, with an annual death rate of approximately 23%. Sudden cardiac death (SCD) is the single largest cause of death in dialysis patients accounting for approximately 60% of all cardiac deaths and 25% of all-cause mortality. Interventions aiming at reducing cardiovascular mortality, especially SCD, in dialysis patients are therefore extremely important and clinically highly relevant. The purpose of this review is to give an outline of the epidemiology...
Abstract
