6143 results
Cited 6 times since 2020 (1.2 per year)
source: EuropePMC
JACC. Clinical electrophysiology,
Volume 6, Issue 9, 12 2 2020, Pages 1073-1085
RV Tissue Heterogeneity on CT: A Novel Tool to Identify the VT Substrate in ARVC.
Venlet J, Tao Q, de Graaf MA, Glashan CA, de Riva Silva M, van der Geest RJ, Scholte AJ, Piers SRD, Zeppenfeld K
Objectives: This study sought to evaluate whether right ventricular (RV) tissue heterogeneity on computed tomography (CT): 1) is associated with conduction delay in arrhythmogenic right ventricular cardiomyopathy (ARVC); and 2) distinguishes patients with ARVC from those with exercise-induced arrhythmogenic remodeling (EIAR) and control individuals. Background: ARVC is characterized by fibrofatty replacement, related to conduction delay and ventricular tachycardias. Distinguishing ARVC from acqu...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
SAGE open medical case reports,
Volume 8, 8 2 2020, Pages 2050313X20918989
A novel approach to resolve severe mediastinal and subcutaneous emphysema occurring in Pneumocystis jirovecii pneumonia using vacuum-assisted closure therapy.
Bouwmeester NH, Kieft H, Shahin GM, Nierich AP
A 50-year-old human immunodeficiency virus positive patient who was diagnosed with Pneumocystis jirovecii pneumonia developed severe subcutaneous and mediastinal emphysema, which was progressive despite low pressure mechanical ventilation. Infraclavicular skin incisions and vacuum-assisted closure therapy were used to resolve the emphysema. The subcutaneous emphysema decreased significantly, and after 1 week the vacuum-assisted closure therapy was ended successfully. This technique has previousl...
Abstract
Cited 12 times since 2020 (2.5 per year)
source: EuropePMC
PloS one,
Volume 15, Issue 5, 6 1 2020, Pages e0232573
Automatic segmentation of multiple cardiovascular structures from cardiac computed tomography angiography images using deep learning.
Baskaran L, Al'Aref SJ, Maliakal G, Lee BC, Xu Z, Choi JW, Lee SE, Sung JM, Lin FY, Dunham S, Mosadegh B, Kim YJ, Gottlieb I, Lee BK, Chun EJ, Cademartiri F, Maffei E, Marques H, Shin S, Choi JH, Chinnaiyan K, Hadamitzky M, Conte E, Andreini D, Pontone G, Budoff MJ, Leipsic JA, Raff GL, Virmani R, Samady H, Stone PH, Berman DS, Narula J, Bax JJ, Chang HJ, Min JK, Shaw LJ
Objectives: To develop, demonstrate and evaluate an automated deep learning method for multiple cardiovascular structure segmentation. Background: Segmentation of cardiovascular images is resource-intensive. We design an automated deep learning method for the segmentation of multiple structures from Coronary Computed Tomography Angiography (CCTA) images. Methods: Images from a multicenter registry of patients that underwent clinically-indicated CCTA were used. The proximal ascending and descendi...
Abstract
Cited 13 times since 2020 (2.7 per year)
source: EuropePMC
Journal of magnetic resonance imaging : JMRI,
Volume 52, Issue 4, 6 1 2020, Pages 971-977
How to Measure the Aorta Using MRI: A Practical Guide.
van Hout MJ, Scholte AJ, Juffermans JF, Westenberg JJ, Zhong L, Zhou X, Schalla SM, Hope MD, Bremerich J, Kramer CM, Dewey M, Ordovas KG, Bluemke DA, Lamb HJ
Abstract
Cited 15 times since 2020 (3.1 per year)
source: EuropePMC
Allergy,
Volume 75, Issue 9, 5 1 2020, Pages 2376-2379
Two-year drug survival of dupilumab in a large cohort of difficult-to-treat adult atopic dermatitis patients compared to cyclosporine A and methotrexate: Results from the BioDay registry.
Spekhorst LS, Ariëns LFM, van der Schaft J, Bakker DS, Kamsteeg M, Oosting AJ, de Ridder I, Sloeserwij A, Romeijn GLE, de Graaf M, Haeck I, Thijs JL, Schuttelaar MLA, de Bruin-Weller MS
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography,
Volume 33, Issue 8, 4 1 2020, Pages 964-972
Correlates and Long-Term Implications of Left Ventricular Mechanical Dispersion by Two-Dimensional Speckle-Tracking Echocardiography in Patients with ST-Segment Elevation Myocardial Infarction.
Abou R, Goedemans L, van der Bijl P, Fortuni F, Prihadi EA, Mertens B, Schalij MJ, Ajmone Marsan N, Bax JJ, Delgado V
Background: Left ventricular (LV) mechanical dispersion (LVMD), measured with speckle-tracking echocardiography (STE) after ST-segment elevation myocardial infarction (STEMI), has been proposed as a measurement of regional heterogeneity of myocardial contraction and may reflect changes in the myocardial structure (e.g., fibrosis or edema). Further insight into this parameter may aid in the risk stratification of STEMI patients. Methods: A total of 1,000 STEMI patients (77% male, 60 ± 12 years) t...
Abstract
Cited 5 times since 2020 (1 per year)
source: EuropePMC
Pediatric cardiology,
Volume 41, Issue 5, 4 1 2020, Pages 1042-1050
Left and Right Ventricular Impairment Shortly After Correction of Tetralogy of Fallot.
Terol C, Kamphuis VP, Hazekamp MG, Blom NA, Ten Harkel ADJ
Surgical repair of Tetralogy of Fallot (ToF) is usually performed in the first months of life with low early postoperative mortality. During long-term follow-up, however, both right (RV) and left ventricular (LV) performances may deteriorate. Tissue Doppler imaging (TDI) and speckle tracking echocardiography (ST) can unmask a diminished RV and LV performance. The objective of the current study was to assess the cardiac performance before and shortly after corrective surgery in ToF patients using...
Abstract
Cited 2 times since 2020 (0.4 per year)
source: EuropePMC
Journal of cardiovascular computed tomography,
Volume 15, Issue 1, 1 1 2020, Pages 48-55
Temporal changes in FFR<sub>CT</sub>-Guided Management of Coronary Artery Disease - Lessons from the ADVANCE Registry.
Nous F, Budde RPJ, Fairbairn TA, Akasaka T, Nørgaard BL, Berman DS, Raff G, Hurwitz-Koweek LM, Pontone G, Kawasaki T, Sand NPR, Jensen JM, Amano T, Poon M, Øvrehus KA, Sonck J, Rabbat MG, Mullen S, De Bruyne B, Rogers C, Matsuo H, Bax JJ, Leipsic J, Patel MR, Nieman K
Background: The ADVANCE registry is a large prospective study of outcomes and resource utilization in patients undergoing coronary computed tomography angiography (CCTA) and CT-based fractional flow reserve (FFRCT). As experience with new technologies and practices develops over time, we investigated temporal changes in the use of FFRCT within the ADVANCE registry. Methods: 5083 patients with coronary artery disease (CAD) on CCTA were prospectively enrolled in the ADVANCE registry and were divid...
Abstract
Cited 4 times since 2020 (0.8 per year)
source: EuropePMC
European heart journal,
Volume 41, Issue 20, 1 1 2020, Pages 1915-1917
Left ventricular myocardial fibrosis: a marker of bad prognosis in symptomatic severe aortic stenosis.
Kong WKF, Bax JJ, Delgado V
Abstract
Cited 15 times since 2020 (3.1 per year)
source: EuropePMC
European heart journal,
Volume 41, Issue 20, 1 1 2020, Pages 1932-1940
Uncertainties and challenges in surgical and transcatheter tricuspid valve therapy: a state-of-the-art expert review.
Chang CC, Veen KM, Hahn RT, Bogers AJJC, Latib A, Oei FBS, Abdelghani M, Modolo R, Ho SY, Abdel-Wahab M, Fattouch K, Bosmans J, Caliskan K, Taramasso M, Serruys PW, Bax JJ, van Mieghem NMDA, Takkenberg JJM, Lurz P, Modine T, Soliman O
Tricuspid regurgitation (TR) is a frequent and complex problem, commonly combined with left-sided heart disease, such as mitral regurgitation. Significant TR is associated with increased mortality if left untreated or recurrent after therapy. Tricuspid regurgitation was historically often disregarded and remained undertreated. Surgery is currently the only Class I Guideline recommended therapy for TR, in the form of annuloplasty, leaflet repair, or valve replacement. As growing experience of tra...
Abstract
Cited 22 times since 2020 (4.5 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 21, Issue 5, 1 1 2020, Pages 479-488
Clinical risk factors and atherosclerotic plaque extent to define risk for major events in patients without obstructive coronary artery disease: the long-term coronary computed tomography angiography CONFIRM registry.
van Rosendael AR, Bax AM, Smit JM, van den Hoogen IJ, Ma X, Al'Aref S, Achenbach S, Al-Mallah MH, Andreini D, Berman DS, Budoff MJ, Cademartiri F, Callister TQ, Chang HJ, Chinnaiyan K, Chow BJW, Cury RC, DeLago A, Feuchtner G, Hadamitzky M, Hausleiter J, Kaufmann PA, Kim YJ, Leipsic JA, Maffei E, Marques H, de Araújo Gonçalves P, Pontone G, Raff GL, Rubinshtein R, Villines TC, Gransar H, Lu Y, Peña JM, Lin FY, Shaw LJ, Min JK, Bax JJ
Aims: In patients without obstructive coronary artery disease (CAD), we examined the prognostic value of risk factors and atherosclerotic extent. Methods and results: Patients from the long-term CONFIRM registry without prior CAD and without obstructive (≥50%) stenosis were included. Within the groups of normal coronary computed tomography angiography (CCTA) (N = 1849) and non-obstructive CAD (N = 1698), the prognostic value of traditional clinical risk factors and atherosclerotic extent (segmen...
Abstract
Cited 8 times since 2020 (1.6 per year)
source: EuropePMC
JMIR research protocols,
Volume 9, Issue 5, 1 1 2020, Pages e17419
Improving Hand Hygiene Compliance in Nursing Homes: Protocol for a Cluster Randomized Controlled Trial (HANDSOME Study).
Teesing GR, Erasmus V, Petrignani M, Koopmans MPG, de Graaf M, Vos MC, Klaassen CHW, Verduijn-Leenman A, Schols JMGA, Richardus JH, Voeten HACM
Background: Hand hygiene compliance is considered the most (cost-)effective measure for preventing health care-associated infections. While hand hygiene interventions have frequently been implemented and assessed in hospitals, there is limited knowledge about hand hygiene compliance in other health care settings and which interventions and implementation methods are effective. Objective: This study aims to evaluate the effect of a multimodal intervention to increase hand hygiene compliance of nu...
Abstract
Cited 1 times since 2020 (0.2 per year)
source: EuropePMC
Interactive cardiovascular and thoracic surgery,
Volume 30, Issue 5, 1 1 2020, Pages 780-782
Intraoperative cryoablation in late pulmonary valve replacement for tetralogy of Fallot.
Nevvazhay T, Zeppenfeld K, Brouwer C, Hazekamp M
Ventricular tachyarrhythmia (VT) is a major cause of late morbidity and mortality in patients who underwent surgical repair of tetralogy of Fallot. The majority of VTs are monomorphic macro-reentrant VT (MVT) and depend on slow conducting areas of diseased myocardium bordered by unexcitable tissue (anatomical isthmuses). Myocardial fibrosis due to surgical incisions, patch material and valve annuli are typical boundaries of anatomical isthmuses (AI). The conducting myocardium between the pulmona...
Abstract
Cited 1048 times since 2020 (214.4 per year)
source: EuropePMC
Science (New York, N.Y.),
Volume 369, Issue 6499, 1 1 2020, Pages 50-54
SARS-CoV-2 productively infects human gut enterocytes.
Lamers MM, Beumer J, van der Vaart J, Knoops K, Puschhof J, Breugem TI, Ravelli RBG, Paul van Schayck J, Mykytyn AZ, Duimel HQ, van Donselaar E, Riesebosch S, Kuijpers HJH, Schipper D, van de Wetering WJ, de Graaf M, Koopmans M, Cuppen E, Peters PJ, Haagmans BL, Clevers H
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can cause coronavirus disease 2019 (COVID-19), an influenza-like disease that is primarily thought to infect the lungs with transmission through the respiratory route. However, clinical evidence suggests that the intestine may present another viral target organ. Indeed, the SARS-CoV-2 receptor angiotensin-converting enzyme 2 (ACE2) is highly expressed on differentiated enterocytes. In human small intestinal organoids (hSIOs), enterocyt...
Abstract
Cited 25 times since 2020 (5.1 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 75, Issue 18, 1 1 2020, Pages 2297-2308
Cost-Effectiveness of Alirocumab in Patients With Acute Coronary Syndromes: The ODYSSEY OUTCOMES Trial.
Bhatt DL, Briggs AH, Reed SD, Annemans L, Szarek M, Bittner VA, Diaz R, Goodman SG, Harrington RA, Higuchi K, Joulain F, Jukema JW, Li QH, Mahaffey KW, Sanchez RJ, Roe MT, Lopes RD, White HD, Zeiher AM, Schwartz GG, Gabriel Steg P, ODYSSEY OUTCOMES Investigators
Background: Cholesterol reduction with proprotein convertase subtilisin-kexin type 9 inhibitors reduces ischemic events; however, the cost-effectiveness in statin-treated patients with recent acute coronary syndrome remains uncertain. Objectives: This study sought to determine whether further cholesterol reduction with alirocumab would be cost-effective in patients with a recent acute coronary syndrome on optimal statin therapy. Methods: A cost-effectiveness model leveraging patient-level data f...
Abstract
Cited 10 times since 2020 (2 per year)
source: EuropePMC
Nucleic acids research,
Volume 48, Issue 8, 1 1 2020, Pages 4161-4178
A multi-layered structure of the interphase chromocenter revealed by proximity-based biotinylation.
Kochanova NY, Schauer T, Mathias GP, Lukacs A, Schmidt A, Flatley A, Schepers A, Thomae AW, Imhof A
During interphase centromeres often coalesce into a small number of chromocenters, which can be visualized as distinct, DAPI dense nuclear domains. Intact chromocenters play a major role in maintaining genome stability as they stabilize the transcriptionally silent state of repetitive DNA while ensuring centromere function. Despite its biological importance, relatively little is known about the molecular composition of the chromocenter or the processes that mediate chromocenter formation and mai...
Abstract
Cited 3 times since 2020 (0.6 per year)
source: EuropePMC
International wound journal,
Volume 17, Issue 5, 30 5 2020, Pages 1225-1230
Validation of the Dutch translation of the Cardiff wound impact schedule for evaluation of the health-related quality of life of patients with chronic wounds.
van Doorn LP, Sijberden JP, Brouwers JJWM, Goossens LD, Hamming JF
The aim of this study was to validate a Dutch translation of the Cardiff wound impact schedule (CWIS), a disease-specific instrument to measure the health-related quality of life (HRQoL) in patients with chronic leg ulcers. To achieve this, the original instrument was translated. A total of 83 patients with chronic lower leg ulcers were included and completed the translated instrument and SF36 at baseline after assessment of their wound severity. Follow-up was performed 1 week after inclusion. T...
Abstract
Cited 7 times since 2020 (1.4 per year)
source: EuropePMC
JACC. Clinical electrophysiology,
Volume 6, Issue 6, 29 5 2020, Pages 696-707
Electroanatomical Voltage Mapping to Distinguish Right-Sided Cardiac Sarcoidosis From Arrhythmogenic Right Ventricular Cardiomyopathy.
Hoogendoorn JC, Sramko M, Venlet J, Siontis KC, Kumar S, Singh R, Nakajima I, Piers SRD, de Riva Silva M, Glashan CA, Crawford T, Tedrow UB, Stevenson WG, Bogun F, Zeppenfeld K
Objectives: This study sought to investigate the value of electroanatomical voltage mapping (EAVM) to distinguish cardiac sarcoidosis (CS) from arrhythmogenic right ventricular cardiomyopathy (ARVC) in patients with ventricular tachycardia from the right ventricle (RV). Background: CS can mimic ARVC. Because scar in ARVC is predominantly subepicardial, this study hypothesized that the relative sizes of endocardial low bipolar voltage (BV) to low unipolar voltage (UV) areas may distinguish CS fro...
Abstract
Cited 21 times since 2020 (4.3 per year)
source: EuropePMC
Heart rhythm O2,
Volume 1, Issue 1, 27 4 2020, Pages 3-9
Atrial fibrillation detection from raw photoplethysmography waveforms: A deep learning application.
Aschbacher K, Yilmaz D, Kerem Y, Crawford S, Benaron D, Liu J, Eaton M, Tison GH, Olgin JE, Li Y, Marcus GM
Background: Atrial fibrillation (AF), a common cause of stroke, often is asymptomatic. Smartphones and smartwatches can detect AF using heart rate patterns inferred using photoplethysmography (PPG); however, enhanced accuracy is required to reduce false positives in screening populations. Objective: The purpose of this study was to test the hypothesis that a deep learning algorithm given raw, smartwatch-derived PPG waveforms would discriminate AF from normal sinus rhythm better than algorithms u...
Abstract
Annals of vascular surgery,
Volume 68, 24 4 2020, Pages 234-244
National Numbers of Secondary Aortic Reinterventions after Primary Abdominal Aortic Aneurysm Surgery from the Dutch Surgical Aneurysm Audit.
Karthaus EG, Vahl A, Elsman BHP, Wouters MWJM, de Borst GJ, Hamming JF, Dutch Society of Vascular Surgery, Steering Committee of the Dutch Surgical Aneurysm Audit, Dutch Institute for Clinical Auditing
Background: Long-term secondary aortic reinterventions (SARs) can be a sign of (lack of) effectiveness of abdominal aortic aneurysm (AAA) surgery. This study provides insight into the national number of SARs after primary AAA repair by endovascular aneurysm repair (EVAR) or by open surgical repair in the Netherlands. Methods: Observational study included all patients undergoing SAR between 2016 and 2017, registered in the compulsory Dutch Surgical Aneurysm Audit (DSAA). The DSAA started in 2013,...
Abstract
