6139 results
Cited 37 times since 2019 (6.5 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 26, 1 1 2019, Pages 2142-2151
Cardiac arrest in takotsubo syndrome: results from the InterTAK Registry.
Gili S, Cammann VL, Schlossbauer SA, Kato K, D'Ascenzo F, Di Vece D, Jurisic S, Micek J, Obeid S, Bacchi B, Szawan KA, Famos F, Sarcon A, Levinson R, Ding KJ, Seifert B, Lenoir O, Bossone E, Citro R, Franke J, Napp LC, Jaguszewski M, Noutsias M, Münzel T, Knorr M, Heiner S, Katus HA, Burgdorf C, Schunkert H, Thiele H, Bauersachs J, Tschöpe C, Pieske BM, Rajan L, Michels G, Pfister R, Cuneo A, Jacobshagen C, Hasenfuß G, Karakas M, Koenig W, Rottbauer W, Said SM, Braun-Dullaeus RC, Banning A, Cuculi F, Kobza R, Fischer TA, Vasankari T, Airaksinen KEJ, Opolski G, Dworakowski R, MacCarthy P, Kaiser C, Osswald S, Galiuto L, Crea F, Dichtl W, Empen K, Felix SB, Delmas C, Lairez O, El-Battrawy I, Akin I, Borggrefe M, Gilyarova E, Shilova A, Gilyarov M, Horowitz JD, Kozel M, Tousek P, Widimský P, Winchester DE, Ukena C, Gaita F, Di Mario C, Wischnewsky MB, Bax JJ, Prasad A, Böhm M, Ruschitzka F, Lüscher TF, Ghadri JR, Templin C
Aims: We aimed to evaluate the frequency, clinical features, and prognostic implications of cardiac arrest (CA) in takotsubo syndrome (TTS). Methods and results: We reviewed the records of patients with CA and known heart rhythm from the International Takotsubo Registry. The main outcomes were 60-day and 5-year mortality. In addition, predictors of mortality and predictors of CA during the acute TTS phase were assessed. Of 2098 patients, 103 patients with CA and known heart rhythm during CA were...
Abstract
Cited 54 times since 2019 (9.4 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 74, Issue 4, 1 1 2019, Pages 550-563
Staging Cardiac Damage in Patients With Asymptomatic Aortic Valve Stenosis.
Tastet L, Tribouilloy C, Maréchaux S, Vollema EM, Delgado V, Salaun E, Shen M, Capoulade R, Clavel MA, Arsenault M, Bédard É, Bernier M, Beaudoin J, Narula J, Lancellotti P, Bax JJ, Généreux P, Pibarot P
Background: The optimal timing of intervention in patients with asymptomatic severe aortic stenosis (AS) remains controversial. Objectives: This multicenter study sought to test and validate the prognostic value of the staging of cardiac damage in patients with asymptomatic moderate to severe AS. Methods: This study retrospectively analyzed the clinical, Doppler echocardiographic, and outcome data that were prospectively collected in 735 asymptomatic patients (71 ± 14 years of age; 60% men) with...
Abstract
Cited 5 times since 2019 (0.9 per year)
source: EuropePMC
The American journal of cardiology,
Volume 124, Issue 6, 1 1 2019, Pages 892-898
Defining Subclinical Myocardial Dysfunction and Implications for Patients With Diabetes Mellitus and Preserved Ejection Fraction.
Ng ACT, Bertini M, Ewe SH, van der Velde ET, Leung DY, Delgado V, Bax JJ
Left ventricular (LV) global longitudinal strain (GLS) can detect subclinical myocardial systolic dysfunction in individuals with diabetes. The present study investigates the clinical usefulness and incremental net benefit of identifying subclinical myocardial systolic dysfunction in individuals with diabetes. A cohort of 397 type 2 diabetic individuals was followed up for the occurrence of all-cause mortality. Clinical and echocardiographic data of diabetic patients were assessed retrospectivel...
Abstract
Cited 1 times since 2019 (0.2 per year)
source: EuropePMC
European heart journal,
Volume 40, Issue 27, 1 1 2019, Pages 2203-2205
Characterizing mitral regurgitation in a contemporary population: prognostic implications.
Delgado V, Ajmone Marsan N, Bax JJ
Abstract
Cited 25 times since 2019 (4.4 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 74, Issue 4, 1 1 2019, Pages 538-549
Staging Cardiac Damage in Patients With Symptomatic Aortic Valve Stenosis.
Vollema EM, Amanullah MR, Ng ACT, van der Bijl P, Prevedello F, Sin YK, Prihadi EA, Marsan NA, Ding ZP, Généreux P, Pibarot P, Leon MB, Narula J, Ewe SH, Delgado V, Bax JJ
Background: In severe aortic stenosis (AS), patients often show extra-aortic valvular injury. Recently, a new staging system for severe AS has been proposed on the basis of the extent of cardiac damage. Objectives: The present study evaluated the prevalence and prognostic impact of these different stages of cardiac damage in a large, real-world, multicenter cohort of symptomatic severe AS patients. Methods: From the ongoing registries from 2 academic institutions, a total of 1,189 symptomatic se...
Abstract
Cited 38 times since 2019 (6.6 per year)
source: EuropePMC
JAMA cardiology,
Volume 4, Issue 7, 1 1 2019, Pages 613-619
Effect of the PCSK9 Inhibitor Evolocumab on Total Cardiovascular Events in Patients With Cardiovascular Disease: A Prespecified Analysis From the FOURIER Trial.
Murphy SA, Pedersen TR, Gaciong ZA, Ceska R, Ezhov MV, Connolly DL, Jukema JW, Toth K, Tikkanen MJ, Im K, Wiviott SD, Kurtz CE, Honarpour N, Giugliano RP, Keech AC, Sever PS, Sabatine MS
Importance: The PCSK9 inhibitor evolocumab reduced low-density lipoprotein cholesterol and first cardiovascular events in the Further Cardiovascular Outcomes Research With PCSK9 Inhibition in Subjects With Elevated Risk (FOURIER) trial, but patients remain at high risk of recurrent cardiovascular events. Objective: To evaluate the effect of evolocumab on total cardiovascular events, given the importance of total number of cardiovascular events to patients, clinicians, and health economists. Desi...
Abstract
Cited 15 times since 2019 (2.6 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 20, Issue 7, 1 1 2019, Pages 740-748
Determinants and prognostic implications of left ventricular mechanical dispersion in aortic stenosis.
Prihadi EA, Vollema EM, Ng ACT, Ajmone Marsan N, Bax JJ, Delgado V
Aims: The present study aimed at investigating the association between left ventricular (LV) mechanical dispersion measured with speckle tracking echocardiography and severity of aortic stenosis (AS) and its impact on prognosis. Methods and results: This retrospective study included 630 patients [age 72 (62-78) years, 61.4% men] with various grades of AS (mild AS, 19.8%; moderate AS, 37.0%; severe AS, 43.2%). LV mechanical dispersion (defined as standard deviation of time from Q/R on electrocard...
Abstract
Cited 113 times since 2019 (19.8 per year)
source: EuropePMC
The lancet. Diabetes & endocrinology,
Volume 7, Issue 8, 1 1 2019, Pages 618-628
Effects of alirocumab on cardiovascular and metabolic outcomes after acute coronary syndrome in patients with or without diabetes: a prespecified analysis of the ODYSSEY OUTCOMES randomised controlled trial.
Ray KK, Colhoun HM, Szarek M, Baccara-Dinet M, Bhatt DL, Bittner VA, Budaj AJ, Diaz R, Goodman SG, Hanotin C, Harrington RA, Jukema JW, Loizeau V, Lopes RD, Moryusef A, Murin J, Pordy R, Ristic AD, Roe MT, Tuñón J, White HD, Zeiher AM, Schwartz GG, Steg PG, ODYSSEY OUTCOMES Committees and Investigators
Background: After acute coronary syndrome, diabetes conveys an excess risk of ischaemic cardiovascular events. A reduction in mean LDL cholesterol to 1·4-1·8 mmol/L with ezetimibe or statins reduces cardiovascular events in patients with an acute coronary syndrome and diabetes. However, the efficacy and safety of further reduction in LDL cholesterol with an inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9) after acute coronary syndrome is unknown. We aimed to explore this issue...
Abstract
Cited 3 times since 2019 (0.5 per year)
source: EuropePMC
Nature genetics,
Volume 51, Issue 7, 1 1 2019, Pages 1191-1192
Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity.
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T, Giri A, Graff M, Guo X, Hendricks AE, Karaderi T, Lempradl A, Locke AE, Mahajan A, Marouli E, Sivapalaratnam S, Young KL, Alfred T, Feitosa MF, Masca NGD, Manning AK, Medina-Gomez C, Mudgal P, Ng MCY, Reiner AP, Vedantam S, Willems SM, Winkler TW, Abecasis G, Aben KK, Alam DS, Alharthi SE, Allison M, Amouyel P, Asselbergs FW, Auer PL, Balkau B, Bang LE, Barroso I, Bastarache L, Benn M, Bergmann S, Bielak LF, Blüher M, Boehnke M, Boeing H, Boerwinkle E, Böger CA, Bork-Jensen J, Bots ML, Bottinger EP, Bowden DW, Brandslund I, Breen G, Brilliant MH, Broer L, Brumat M, Burt AA, Butterworth AS, Campbell PT, Cappellani S, Carey DJ, Catamo E, Caulfield MJ, Chambers JC, Chasman DI, Chen YI, Chowdhury R, Christensen C, Chu AY, Cocca M, Collins FS, Cook JP, Corley J, Galbany JC, Cox AJ, Crosslin DS, Cuellar-Partida G, D'Eustacchio A, Danesh J, Davies G, Bakker PIW, Groot MCH, Mutsert R, Deary IJ, Dedoussis G, Demerath EW, Heijer M, Hol
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Abstract
Cited 11 times since 2019 (1.9 per year)
source: EuropePMC
Journal of vascular surgery,
Volume 70, Issue 1, 1 1 2019, Pages 286-297.e1
A systematic review of the use of near-infrared fluorescence imaging in patients with peripheral artery disease.
van den Hoven P, Ooms S, van Manen L, van der Bogt KEA, van Schaik J, Hamming JF, Vahrmeijer AL, van der Vorst JR, Mieog JSD
Objective: In the diagnosis of peripheral artery disease (PAD), the ankle-brachial index plays an important role. However, results of the ankle-brachial index are unreliable in patients with severe media sclerosis. Near-infrared (NIR) fluorescence imaging using indocyanine green (ICG) can provide information about tissue perfusion and has already been studied in oncologic, reconstructive, and cardiac surgery. For patients with PAD, this technique might give insight into skin perfusion and thereb...
Abstract
Cited 4 times since 2019 (0.7 per year)
source: EuropePMC
European radiology experimental,
Volume 3, Issue 1, 20 3 2019, Pages 24
The effects of age at correction of aortic coarctation and recurrent obstruction on adolescent patients: MRI evaluation of wall shear stress and pulse wave velocity.
Juffermans JF, Nederend I, van den Boogaard PJ, Ten Harkel ADJ, Hazekamp MG, Lamb HJ, Roest AAW, Westenberg JJM
Background: Coarctation patients before curative reconstruction are exposed to abnormal flow patterns which potentially could cause wall deterioration. This study evaluated the effect of age at correction on the pulse wave velocity (PWV) and peak wall shear stress (WSS) in adolescent patients with corrected coarctation. Effects of valve morphology and presence of reobstruction were also evaluated. Methods: Twenty-one patients aged 13.7 ± 2.6 years (mean ± standard deviation) were included (bicus...
Abstract
Cited 3 times since 2019 (0.5 per year)
source: EuropePMC
The American journal of medicine,
Volume 132, Issue 12, 20 3 2019, Pages 1466-1474.e4
Cognitive Function in Dementia-Free Subjects and Survival in Old Age: The PROSPER Study.
Rostamian S, de Haan S, van der Grond J, van Buchem MA, Ford I, Jukema JW, Sabayan B
Background: Impairment in domain-specific cognitive function is associated with the increased risk of mortality. We prospectively evaluated the association of executive function and memory with the risk of long-term mortality in dementia-free older subjects. Moreover, we investigated the role of structural brain abnormalities in this association. Methods: We included 547 dementia-free participants (mean age 78 years, 56.5% male) from the nested magnetic resonance imaging sub-study of the PROspec...
Abstract
Cited 12 times since 2019 (2.1 per year)
source: EuropePMC
PloS one,
Volume 14, Issue 6, 14 2 2019, Pages e0217582
Hypercholesterolemia affects cardiac function, infarct size and inflammation in APOE*3-Leiden mice following myocardial ischemia-reperfusion injury.
Pluijmert NJ, den Haan MC, van Zuylen VL, Steendijk P, de Boer HC, van Zonneveld AJ, Fibbe WE, Schalij MJ, Quax PHA, Atsma DE
Background: Hypercholesterolemia is a major risk factor for ischemic heart disease including acute myocardial infarction. However, long-term effects of hypercholesterolemia in a rodent myocardial ischemia-reperfusion injury model are unknown. Therefore, the effects of diet-induced hypercholesterolemia on cardiac function and remodeling were investigated up to eight weeks after myocardial ischemia-reperfusion (MI-R) injury which was induced in either normocholesterolemic (NC-MI) or hypercholester...
Abstract
Cited 3 times since 2019 (0.5 per year)
source: EuropePMC
Journal of cardiothoracic and vascular anesthesia,
Volume 33, Issue 12, 14 2 2019, Pages 3273-3280
Vasoplegia After Restrictive Mitral Annuloplasty for Functional Mitral Regurgitation in Patients With Heart Failure.
van Vessem ME, Petrus AHJ, Palmen M, Braun J, Schalij MJ, Klautz RJM, Beeres SLMA
Objectives: Patients undergoing heart failure surgery are at risk for developing postoperative vasoplegia. The aim of this study was to determine the incidence, survival, and predictors of vasoplegia in heart failure patients undergoing mitral valve repair for functional mitral regurgitation and to evaluate the effect of ischemic versus non-ischemic etiology. Design: Retrospective. Setting: University medical center, single institutional. Participants: Heart failure patients with functional mitr...
Abstract
Cited 6 times since 2019 (1 per year)
source: EuropePMC
Frontiers in cardiovascular medicine,
Volume 6, 13 2 2019, Pages 77
CD8+ T Cells Protect During Vein Graft Disease Development.
Simons KH, de Vries MR, Peters HAB, Jukema JW, Quax PHA, Arens R
Aims: Vein grafts are frequently used conduits for arterial reconstruction in patients with cardiovascular disease. Unfortunately, vein graft disease (VGD) causes diminished patency rates. Innate immune system components are known to contribute to VGD. However, the role of T cells has yet to be established. The purpose of this study was to investigate the role of T cells and T cell activation pathways via the T cell receptor (TCR), co-stimulation and bystander effect in VGD. Methods and results:...
Abstract
Cited 18 times since 2019 (3.1 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 13, Issue 2 Pt 1, 12 2 2019, Pages 425-434
Application of Low Tube Potentials in CCTA: Results From the PROTECTION VI Study.
Stocker TJ, Leipsic J, Hadamitzky M, Chen MY, Rubinshtein R, Deseive S, Heckner M, Bax JJ, Kitagawa K, Marques H, Schmermund A, Silva C, Mahmarian J, Kang JW, Grove EL, Lesser J, Massberg S, Hausleiter J
Objectives: The aim of this study was to assess the use of low tube potentials for coronary computed tomography angiography (CCTA) in worldwide clinical practice and its influence on radiation exposure, contrast agent volume, and image quality. Background: CCTA is frequently used in clinical practice. Lowering of tube potential is a potent method to reduce radiation exposure and to economize contrast agent volume. Methods: CCTAs of 4,006 patients from 61 international study sites were analyzed r...
Abstract
Cited 21 times since 2019 (3.6 per year)
source: EuropePMC
JACC. Cardiovascular imaging,
Volume 13, Issue 2 Pt 2, 12 2 2019, Pages 577-585
Prognostic Value of Global Longitudinal Strain and Etiology After Surgery for Primary Mitral Regurgitation.
Hiemstra YL, Tomsic A, van Wijngaarden SE, Palmen M, Klautz RJM, Bax JJ, Delgado V, Ajmone Marsan N
Objectives: This study sought to investigate whether left ventricular (LV) global longitudinal strain (GLS) is associated with long-term outcome after mitral valve (MV) surgery for primary mitral regurgitation (MR) and assess the differences in outcome according to MR etiology: Barlow's disease (BD), fibroelastic deficiency (FED), and forme fruste (FF). Background: Appropriate timing of MV surgery for primary MR is still challenging and may differ according to the etiology. In these patient...
Abstract
Cited 47 times since 2019 (8.1 per year)
source: EuropePMC
Circulation,
Volume 140, Issue 10, 12 2 2019, Pages 836-845
Prognostic Implications of Right Ventricular Remodeling and Function in Patients With Significant Secondary Tricuspid Regurgitation.
Dietz MF, Prihadi EA, van der Bijl P, Goedemans L, Mertens BJA, Gursoy E, van Genderen OS, Ajmone Marsan N, Delgado V, Bax JJ
Background: In patients with significant (moderate and severe) tricuspid regurgitation (TR), the decision to intervene is influenced by right ventricular (RV) size and function. RV remodeling in significant secondary TR has been underexplored. The aim of this study was to characterize RV remodeling in patients with significant secondary TR and to investigate its prognostic implications. Methods: RV remodeling was characterized by transthoracic echocardiography in 1292 patients with significant s...
Abstract
Cited 2 times since 2019 (0.3 per year)
source: EuropePMC
Seizure,
Volume 71, 10 2 2019, Pages 50-55
The effect of early midazolam infusion on the duration of pediatric status epilepticus patients.
Ulusoy E, Duman M, Türker HD, Çağlar A, Er A, Akgül F, Çitlenbik H, Öztürk A, Yılmaz D
Purpose: Status epilepticus is one of the most common neurological emergencies in pediatric emergency departments. Although there are different approaches to treatment in the literature, early control of seizure activity is the most important factor determining prognosis. The purpose of this study was to evaluate the effect of early midazolam infusion on seizure duration. Method: This retrospective study included 150 episodes of 135 patients aged one month to 18 years old with status epilepticus...
Abstract
Cited 27 times since 2019 (4.7 per year)
source: EuropePMC
Epigenetics & chromatin,
Volume 12, Issue 1, 6 1 2019, Pages 34
Human monocyte-to-macrophage differentiation involves highly localized gain and loss of DNA methylation at transcription factor binding sites.
Dekkers KF, Neele AE, Jukema JW, Heijmans BT, de Winther MPJ
Background: Macrophages and their precursors monocytes play a key role in inflammation and chronic inflammatory disorders. Monocyte-to-macrophage differentiation and activation programs are accompanied by significant epigenetic remodeling where DNA methylation associates with cell identity. Here we show that DNA methylation changes characteristic for monocyte-to-macrophage differentiation occur at transcription factor binding sites, and, in contrast to what was previously described, are generall...
Abstract
