Research

Publications

Below you can find a list of our published research.

7971 results

Cited 3 times since 2021 (0.8 per year) source: EuropePMC

Circulation. Arrhythmia and electrophysiology, Volume 14, Issue 9, 1 1 2021, Pages e009695 Contemporary Patients With Congenital Heart Disease: Uniform Atrial Tachycardia Substrates Allow for Clear Ablation Endpoints With Improved Long-Term Outcome. Brouwer C, Hebe J, Lukac P, Nürnberg JH, Cosedis Nielsen J, de Riva Silva M, Blom N, Hazekamp M, Zeppenfeld K

[Figure: see text]. Abstract

Cited 309 times since 2021 (82.4 per year) source: EuropePMC

The British journal of surgery, Volume 108, Issue 9, 1 1 2021, Pages 1056-1063 SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. COVIDSurg Collaborative, GlobalSurg Collaborative

Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling. Methods: The primary outcome was the number needed to vaccinate (NNV) to prevent one COVID-19-related death in 1 year. NNVs were based on postoperative SARS-CoV-2 rates and mortality in an international cohort study (surgical patients), and community SARS-CoV-2 incidence and case fatality data (general population). NNV... Abstract

Cited 1 times since 2021 (0.3 per year) source: EuropePMC

Microbiology (Reading, England), Volume 167, Issue 9, 1 1 2021 Functional characterization of a gene cluster responsible for inositol catabolism associated with hospital-adapted isolates of <i>Enterococcus faecium</i>. Top J, Baan J, Bisschop A, Arredondo-Alonso S, van Schaik W, Willems RJL

Enterococcus faecium is a nosocomial, multidrug-resistant pathogen. Whole genome sequence studies revealed that hospital-associated E. faecium isolates are clustered in a separate clade A1. Here, we investigated the distribution, integration site and function of a putative iol gene cluster that encodes for myo-inositol (MI) catabolism. This iol gene cluster was found as part of an ~20 kbp genetic element (iol element), integrated in ICEEfm1 close to its integrase gene in E. faecium isolate E1679... Abstract

Cited 5 times since 2021 (1.3 per year) source: EuropePMC

AIDS (London, England), Volume 35, Issue 11, 1 1 2021, Pages 1845-1850 Using an electronic health record alert to prompt blood-borne virus testing in primary care. Chadwick D, Forbes G, Lawrence C, Lorrimer S, van Schaik P

Background: Late diagnosis of HIV, hepatitis B (HBV) and hepatitis C (HCV) remains relatively common in the UK and many people who present late have missed opportunities for testing in primary care. The objective was to assess the effectiveness and acceptance of a prototype application (BBV_TP1), embedded in a primary care electronic health record (EHR), to increase real-time blood-borne virus (BBV) testing. Methods: This prospective cohort study assessed BBV_TP1 in 14 general practices in North... Abstract

Cited 12 times since 2021 (3.2 per year) source: EuropePMC

European heart journal. Cardiovascular Imaging, Volume 22, Issue 10, 1 1 2021, Pages 1098-1105 EACVI survey on the evaluation of left ventricular diastolic function. Sitges M, Ajmone Marsan N, Cameli M, D'Andrea A, Carvalho RF, Holte E, Michalski B, Podlesnikar T, Popescu BA, Schulz-Menger J, Stankovic I, Haugaa KH, Dweck MR

Aims: The aim of this study is to analyse how current recommendations on left ventricular (LV) diastolic function assessment have been adopted. Identifying potential discrepancies between recommendations and everyday clinical practice would enable us to better understand and address the remaining challenges in this controversial and complex field. Methods and results: A total of 93 centres, mainly from tertiary care settings, responded to the survey. More than three-quarters (77%) of centres fol... Abstract

World journal for pediatric & congenital heart surgery, Volume 12, Issue 5, 1 1 2021, Pages 614-615 Invited Commentary: Residual Lesions and ECMO: Seek and You Shall Find Ways to Narrow the ECMO Gap. Roeleveld PP, Blom NA, Hazekamp MG

Abstract

Cited 1 times since 2021 (0.3 per year) source: EuropePMC

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 23, Issue 9, 1 1 2021, Pages 1487-1492 Five cases of complete atrioventricular block induced by bending forward: unusual but not unique. Saal DP, Thijs RD, Bootsma M, Brignole M, van Dijk JG

Aims: We describe five patients with syncope caused by a complete atrioventricular block (AVB) while they were bending forward, not rising after bending, and aim to describe the occurrence and the association between bending forward and AVB. Methods and results: In two patients, bending forward was the exclusive trigger for syncope, while in the remaining three, other postural changes (sitting down, standing up, and exertion) could also provoke syncope. Complete AVB as the cause of syncope was d... Abstract

Cited 315 times since 2021 (84 per year) source: EuropePMC

European journal of preventive cardiology, Volume 28, Issue 11, 1 1 2021, Pages 1279-1289 EU-Wide Cross-Sectional Observational Study of Lipid-Modifying Therapy Use in Secondary and Primary Care: the DA VINCI study. Ray KK, Molemans B, Schoonen WM, Giovas P, Bray S, Kiru G, Murphy J, Banach M, De Servi S, Gaita D, Gouni-Berthold I, Hovingh GK, Jozwiak JJ, Jukema JW, Kiss RG, Kownator S, Iversen HK, Maher V, Masana L, Parkhomenko A, Peeters A, Clifford P, Raslova K, Siostrzonek P, Romeo S, Tousoulis D, Vlachopoulos C, Vrablik M, Catapano AL, Poulter NR, DA VINCI study

Aims: To provide contemporary data on the implementation of European guideline recommendations for lipid-lowering therapies (LLTs) across different settings and populations and how this impacts low-density lipoprotein cholesterol (LDL-C) goal achievement. Methods and results: An 18 country, cross-sectional, observational study of patients prescribed LLT for primary or secondary prevention in primary or secondary care across Europe. Between June 2017 and November 2018, data were collected at a si... Abstract

Cited 10 times since 2021 (2.7 per year) source: EuropePMC

Open heart, Volume 8, Issue 2, 1 1 2021, Pages e001772 Comparative evaluation of coronary disease burden: bicuspid valve disease is not atheroprotective. Dolmaci OB, Driessen AHG, Klautz RJM, Poelmann R, Lindeman JHN, Grewal N

Objective: Bicuspid aortic valve (BAV) has been associated with less atherosclerosis as compared with tricuspid aortic valve (TAV) patients. It, however, remains unclear whether this reflects the older age of TAV patients and/or accumulation of atherosclerotic risk factors or that the BAV phenotype is atheroprotective. Therefore, we compared the atherosclerotic disease burden of BAV and TAV patients, with that of the general (age-matched) population. Methods: The prevalence of coronary artery di... Abstract

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 60, Issue 3, 1 1 2021, Pages 481-496 Summary: international consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes. Michelena HI, Della Corte A, Evangelista A, Maleszewski JJ, Edwards WD, Roman MJ, Devereux RB, Fernández B, Asch FM, Barker AJ, Sierra-Galan LM, De Kerchove L, Fernandes SM, Fedak PWM, Girdauskas E, Delgado V, Abbara S, Lansac E, Prakash SK, Bissell MM, Popescu BA, Hope MD, Sitges M, Thourani VH, Pibarot P, Chandrasekaran K, Lancellotti P, Borger MA, Forrest JK, Webb J, Milewicz DM, Makkar R, Leon MB, Sanders SP, Markl M, Ferrari VA, Roberts WC, Song JK, Blanke P, White CS, Siu S, Svensson LG, Braverman AC, Bavaria J, Sundt TM, Khoury GE, De Paulis R, Enriquez-Sarano M, Bax JJ, Otto CM, Schäfers HJ

This International evidence-based nomenclature and classification consensus on the congenital bicuspid aortic valve and its aortopathy recognizes 3 types of bicuspid aortic valve: 1. Fused type, with 3 phenotypes: right-left cusp fusion, right-non cusp fusion and left-non cusp fusion; 2. 2-sinus type with 2 phenotypes: Latero-lateral and antero-posterior; and 3. Partial-fusion or forme fruste. This consensus recognizes 3 bicuspid-aortopathy types: 1. Ascending phenotype; root phenotype; and 3. e... Abstract

Cited 7 times since 2021 (1.9 per year) source: EuropePMC

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, Volume 62, Issue 4, 31 5 2021, Pages 630-641 Towards Patient Centred Outcomes for Elective Abdominal Aortic Aneurysm Repair: A Scoping Review of Quality of Life Scales. Bulder RMA, Hamming JF, van Schaik J, Lindeman JHN

Objective: In order to better incorporate the patient's perspective in medical decision making, core outcome sets (COS) are being defined. In the field of abdominal aortic aneurysm (AAA), efforts to capture the patient's perspective focus on generic quantitative quality of life (QoL) scales. The question arises whether these quantitative scales adequately reflect the patient's perspective on QoL, and whether they can be included in the QoL aspect of COS. A scoping review of QoL as... Abstract

Cited 6 times since 2021 (1.6 per year) source: EuropePMC

Frontiers in cardiovascular medicine, Volume 8, 30 5 2021, Pages 687885 Radiation Induces Valvular Interstitial Cell Calcific Response in an <i>in vitro</i> Model of Calcific Aortic Valve Disease. Meerman M, Driessen R, van Engeland NCA, Bergsma I, Steenhuijsen JLG, Kozono D, Aikawa E, Hjortnaes J, Bouten CVC

Background: Mediastinal ionizing radiotherapy is associated with an increased risk of valvular disease, which demonstrates pathological hallmarks similar to calcific aortic valve disease (CAVD). Despite advances in radiotherapy techniques, the prevalence of comorbidities such as radiation-associated valvular disease is still increasing due to improved survival of patients receiving radiotherapy. However, the mechanisms of radiation-associated valvular disease are largely unknown. CAVD is conside... Abstract

Cited 1 times since 2021 (0.3 per year) source: EuropePMC

JMIR cardio, Volume 5, Issue 2, 30 5 2021, Pages e27867 Financial Incentives for Healthy Living for Patients With Cardiac Disease From the Perspective of Health Care Professionals: Interview Study. de Buisonjé D, Van der Geer J, Keesman M, Van der Vaart R, Reijnders T, Wentzel J, Kemps H, Kraaijenhagen R, Janssen V, Evers A

Background: A promising new approach to support lifestyle changes in patients with cardiovascular disease (CVD) is the use of financial incentives. Although financial incentives have proven to be effective, their implementation remains controversial, and ethical objections have been raised. It is unknown whether health care professionals (HCPs) involved in CVD care find it acceptable to provide financial incentives to patients with CVD as support for lifestyle change. Objective: This study aims... Abstract

Cited 6 times since 2021 (1.6 per year) source: EuropePMC

Turkish journal of medical sciences, Volume 51, Issue 4, 30 5 2021, Pages 1640-1646 Impact of COVID-19 on serum melatonin levels and sleep parameters in children Yayıcı Köken Ö, Gültutan P, Güngören MS, Bayhan Gİ, Yılmaz D, Gürkaş E, Özyürek H, Çıtak Kurt AN

Background/aim: This study aimed to analyze the serum melatonin levels and changes in sleep patterns in pediatric patients with
coronavirus disease 2019 (COVID-19). Materials and methods: This study was designed as a descriptive, cross-sectional study. Serum melatonin levels and sleep parameters of children with the diagnosis of COVID-19 who had mild and moderate disease (i.e., COVID-19 group) were compared with those of children admitted with non-COVID-19 nonspecific upper respiratory tract inf... Abstract

Cited 9 times since 2021 (2.4 per year) source: EuropePMC

Clinical research in cardiology : official journal of the German Cardiac Society, Volume 110, Issue 11, 28 4 2021, Pages 1734-1742 Echocardiography-derived total atrial conduction time (PA-TDI duration): risk stratification and guidance in atrial fibrillation management. Müller P, Weijs B, Bemelmans NMAA, Mügge A, Eckardt L, Crijns HJGM, Bax JJ, Linz D, den Uijl DW

Atrial fibrillation (AF) is a major cause of cardiovascular morbidity and mortality. To early detect and to avoid AF-related complications, several cardiac imaging modalities and approaches aim to quantify the severity of the underlying atrial cardiomyopathy (i.e., the extent of atrial remodeling). However, most established cardiac imaging modalities just incorporate single components of atrial remodeling and do not reflect the complete multifactorial process, which may contribute to their limit... Abstract

Cited 19 times since 2021 (5 per year) source: EuropePMC

BMC medicine, Volume 19, Issue 1, 27 4 2021, Pages 211 Interventions to control nosocomial transmission of SARS-CoV-2: a modelling study. Pham TM, Tahir H, van de Wijgert JHHM, Van der Roest BR, Ellerbroek P, Bonten MJM, Bootsma MCJ, Kretzschmar ME

Background: Emergence of more transmissible SARS-CoV-2 variants requires more efficient control measures to limit nosocomial transmission and maintain healthcare capacities during pandemic waves. Yet the relative importance of different strategies is unknown. Methods: We developed an agent-based model and compared the impact of personal protective equipment (PPE), screening of healthcare workers (HCWs), contact tracing of symptomatic HCWs and restricting HCWs from working in multiple units (HCW... Abstract

Cited 5 times since 2021 (1.3 per year) source: EuropePMC

Frontiers in veterinary science, Volume 8, 27 4 2021, Pages 686257 Why Test Purchased Cattle in BVDV Control Programs? Van Duijn L, Santman-Berends I, Biesheuvel M, Mars J, Waldeck F, van Schaik G

Bovine viral diarrhea (BVD) is controlled in many countries by detection and culling of persistently infected (PI) animals. The most important risk factor for BVDV introduction is purchase. An introduced cow can be PI and transmit the virus to other cattle in the herd. If she is not PI but is pregnant, there is still a risk because the subsequently born calf may be PI, when she encountered the virus in early pregnancy. To control this risk, all cows > 1 year from non-BVDV-free herds that are... Abstract

European heart journal. Case reports, Volume 5, Issue 8, 27 4 2021, Pages ytab288 4D flow MRI of type B dissection with later retrograde progression to type A dissection in Marfan: a case report. van Hout MJP, Juffermans JF, Scholte AJ, Lamb HJ

Background: Due to the malfunction of connective tissue, Marfan patients are at increased risk of aortic dissection. Uncomplicated acute type B dissection is usually managed with medical therapy. Retrograde progression or new type A dissection is a relatively rare but often fatal complication that occur most frequently in the first 6 months after acute type B dissection. Case summary: We present a 31-year-old male with Marfan syndrome and a recent uncomplicated type B dissection from the left su... Abstract

Cited 11 times since 2021 (2.9 per year) source: EuropePMC

Journal of cardiovascular development and disease, Volume 8, Issue 9, 26 4 2021, Pages 102 The Coronary Arteries in Adults after the Arterial Switch Operation: A Systematic Review. Engele LJ, Mulder BJM, Schoones JW, Kiès P, Egorova AD, Vliegen HW, Hazekamp MG, Bouma BJ, Jongbloed MRM

Coronary artery status in adults long after the arterial switch operation (ASO) is unclear. We conducted a systematic review to provide an overview of coronary complications during adulthood and to evaluate the value of routine coronary imaging in adults after ASO, in light of current guidelines. Articles were screened for the inclusion of adult ASO patients and data on coronary complications and findings of coronary imaging were collected. A total of 993 adults were followed with a median avail... Abstract

JTCVS open, Volume 8, 25 4 2021, Pages 249-250 Reply from authors: Prosthesis-patient mismatch is not synonymous with elevated transvalvular pressure gradient. Vriesendorp MD, Klautz RJM

Abstract