6139 results
Cited 22 times since 2018 (3.3 per year)
source: EuropePMC
Radiology,
Volume 288, Issue 3, 31 5 2018, Pages 638-655
Mitral Valve Imaging with CT: Relationship with Transcatheter Mitral Valve Interventions.
Weir-McCall JR, Blanke P, Naoum C, Delgado V, Bax JJ, Leipsic J
The role of noninvasive imaging to help guide transcatheter aortic valvular interventions is well established and has grown with the advances in the procedure. With the rapid development of new transcatheter mitral valve interventions there is both an opportunity and a challenge for noninvasive imaging to grow understanding of mitral valve anatomy and disease, help with patient selection, and improve downstream clinical outcomes. This review will discuss the role of both echocardiography and mul...
Abstract
Atherosclerosis,
Volume 278, 31 5 2018, Pages 317-318
The senescence of vascular smooth muscle cells in BAV-associated aortopathy.
Mohamed SA, Grewal N, Gittenberger-de Groot AC
Abstract
Cited 5 times since 2018 (0.8 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 105, Issue 3, 30 5 2018, Pages 196-203
Prognostic value of chronic total occlusions detected on coronary computed tomographic angiography.
Opolski MP, Gransar H, Lu Y, Achenbach S, Al-Mallah MH, Andreini D, Bax JJ, Berman DS, Budoff MJ, Cademartiri F, Callister TQ, Chang HJ, Chinnaiyan K, Chow BJ, Cury RC, DeLago A, Feuchtner GM, Hadamitzky M, Hausleiter J, Kaufmann PA, Kim YJ, Leipsic JA, Maffei EC, Marques H, Pontone G, Raff G, Rubinshtein R, Shaw LJ, Villines TC, Gomez M, Jones EC, Peña JM, Min JK, Lin FY
Objective: Data describing clinical relevance of chronic total occlusion (CTO) identified by coronary CT angiography (CCTA) have not been reported to date. We investigated the prognosis of CTO on CCTA. Methods: We identified 22 828 patients without prior known coronary artery disease (CAD), who were followed for a median of 26 months. Based on CCTA, coronary lesions were graded as normal (no atherosclerosis), non-obstructive (1%-49%), moderate-to-severe (50%-99%) or totally occluded (100%). All-...
Abstract
Cited 1 times since 2018 (0.2 per year)
source: EuropePMC
Heart rhythm,
Volume 16, Issue 1, 29 5 2018, Pages 83-90
Defibrillation testing and clinical outcomes after implantable cardioverter-defibrillator implantation in patients in atrial fibrillation at the time of implant: An analysis from the SIMPLE trial.
Bogdan S, Glikson M, Connolly SJ, Wang J, Hohnloser SH, Appl U, Neuzener J, Mabo P, Vinolas X, Gadler F, van Erven L, Kautzner J, Meeks B, Pogue J, Healey JS
Background: The Shockless IMPLant Evaluation (SIMPLE) trial showed that defibrillation testing (DT) at the time of implantable cardioverter-defibrillator (ICD) implant did not improve shock efficacy or reduce mortality. There are no data regarding the risk of complications, including stroke, among patients with atrial fibrillation (AF) who undergo DT. Objective: The purpose of this prospectively planned substudy of SIMPLE was to evaluate the effect of DT vs no DT on clinical outcomes among patie...
Abstract
Multimedia manual of cardiothoracic surgery : MMCTS,
Volume 2018, 26 4 2018
Subclavicular arteriovenous fistula for univentricular heart palliation.
Caldaroni F, Nevvazhay T, Vladimir S, Hazekamp M
Creation of a subclavicular arteriovenous fistula is a minimally invasive procedure that provides an additional source of arterial blood flow to the pulmonary arteries in patients who have a Glenn shunt but are unsuitable for or at high risk for Fontan completion.
Abstract
Cited 51 times since 2018 (7.7 per year)
source: EuropePMC
Nature communications,
Volume 9, Issue 1, 25 4 2018, Pages 2904
PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.
van Setten J, Brody JA, Jamshidi Y, Swenson BR, Butler AM, Campbell H, Del Greco FM, Evans DS, Gibson Q, Gudbjartsson DF, Kerr KF, Krijthe BP, Lyytikäinen LP, Müller C, Müller-Nurasyid M, Nolte IM, Padmanabhan S, Ritchie MD, Robino A, Smith AV, Steri M, Tanaka T, Teumer A, Trompet S, Ulivi S, Verweij N, Yin X, Arnar DO, Asselbergs FW, Bader JS, Barnard J, Bis J, Blankenberg S, Boerwinkle E, Bradford Y, Buckley BM, Chung MK, Crawford D, den Hoed M, Denny JC, Dominiczak AF, Ehret GB, Eijgelsheim M, Ellinor PT, Felix SB, Franco OH, Franke L, Harris TB, Holm H, Ilaria G, Iorio A, Kähönen M, Kolcic I, Kors JA, Lakatta EG, Launer LJ, Lin H, Lin HJ, Loos RJF, Lubitz SA, Macfarlane PW, Magnani JW, Leach IM, Meitinger T, Mitchell BD, Munzel T, Papanicolaou GJ, Peters A, Pfeufer A, Pramstaller PP, Raitakari OT, Rotter JI, Rudan I, Samani NJ, Schlessinger D, Silva Aldana CT, Sinner MF, Smith JD, Snieder H, Soliman EZ, Spector TD, Stott DJ, Strauch K, Tarasov KV, Thorsteinsdottir U, Uitterlinden AG, Van Wagoner DR, Völke
Electrocardiographic PR interval measures atrio-ventricular depolarization and conduction, and abnormal PR interval is a risk factor for atrial fibrillation and heart block. Our genome-wide association study of over 92,000 European-descent individuals identifies 44 PR interval loci (34 novel). Examination of these loci reveals known and previously not-yet-reported biological processes involved in cardiac atrial electrical activity. Genes in these loci are over-represented in cardiac disease proc...
Abstract
Cited 8 times since 2018 (1.2 per year)
source: EuropePMC
Human pathology,
Volume 81, 25 4 2018, Pages 245-254
The theranostic target prostate-specific membrane antigen is expressed in medullary thyroid cancer.
Lodewijk L, Willems SM, Dreijerink KMA, de Keizer B, van Diest PJ, Schepers A, Morreau H, Bonenkamp HJ, Van Engen-van Grunsven IACH, Kruijff S, van Hemel BM, Links TP, Nieveen van Dijkum E, van Eeden S, Valk GD, Borel Rinkes IHM, Vriens MR
Abstract
Cited 2 times since 2018 (0.3 per year)
source: EuropePMC
International journal of cardiology,
Volume 273, 24 4 2018, Pages 203-206
ECG derived ventricular gradient exceeds echocardiography in the early detection of pulmonary hypertension in scleroderma patients.
Meijer FMM, Kies P, Jongbloed MRM, van Wijngaarden SE, Swenne CA, Man S, Schalij MJ, de Vries-Bouwstra JK, Vliegen HW
Background: Patients with systemic sclerosis (SSc) are at risk for developing pulmonary hypertension (PH) which is a major cause of death in this population. Echocardiographic (TTE) derived pulmonary arterial pressure (PAP) can be unreliable for the early detection of PH. Previous studies demonstrate that the ECG derived ventricular gradient optimized for right ventricular pressure overload (VG-RVPO) can detect PH in a heterogeneous population suspected of PH. The aim of this study is to assess...
Abstract
Cited 11 times since 2018 (1.7 per year)
source: EuropePMC
BMJ quality & safety,
Volume 28, Issue 3, 21 3 2018, Pages 180-189
Connecting perspectives on quality and safety: patient-level linkage of incident, adverse event and complaint data.
de Vos MS, Hamming JF, Chua-Hendriks JJC, Marang-van de Mheen PJ
Background and objective: Incident, adverse event (AE) and complaint data are typically used separately, but may be related at the patient level with one event triggering a cascade of events, ultimately resulting in a complaint. This study examined relations between incidents, AEs and complaints that co-occurred in admissions. Methods: Independently and routinely collected incident, AE and complaint data were retrospectively linked for surgical admissions in an academic centre (2008-2014). Two i...
Abstract
Cited 8 times since 2018 (1.2 per year)
source: EuropePMC
Clinical and experimental rheumatology,
Volume 36 Suppl 113, Issue 4, 18 3 2018, Pages 109-117
To what extent do autoantibodies help to identify high-risk patients in systemic sclerosis?
Boonstra M, Mertens BJA, Bakker JA, Ninaber MK, Ajmone Marsan N, van der Helm-van Mil AHM, Scherer HU, Huizinga TWJ, de Vries-Bouwstra JK
Objectives: To evaluate the additive value of autoantibodies in identifying systemic sclerosis (SSc) patients with high complication risk. Methods: Patients entering the Combined Care In SSc cohort, Leiden University Medical Centre between April 2009 and May 2016 were included. Subgroups of patients were determined using hierarchical clustering, performed on Principal Component Analysis scores, 1) using baseline data of demographic and clinical variables only and 2) with additional use of antibo...
Abstract
Cited 30 times since 2018 (4.5 per year)
source: EuropePMC
Genome biology,
Volume 19, Issue 1, 17 3 2018, Pages 87
Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.
Prins BP, Mead TJ, Brody JA, Sveinbjornsson G, Ntalla I, Bihlmeyer NA, van den Berg M, Bork-Jensen J, Cappellani S, Van Duijvenboden S, Klena NT, Gabriel GC, Liu X, Gulec C, Grarup N, Haessler J, Hall LM, Iorio A, Isaacs A, Li-Gao R, Lin H, Liu CT, Lyytikäinen LP, Marten J, Mei H, Müller-Nurasyid M, Orini M, Padmanabhan S, Radmanesh F, Ramirez J, Robino A, Schwartz M, van Setten J, Smith AV, Verweij N, Warren HR, Weiss S, Alonso A, Arnar DO, Bots ML, de Boer RA, Dominiczak AF, Eijgelsheim M, Ellinor PT, Guo X, Felix SB, Harris TB, Hayward C, Heckbert SR, Huang PL, Jukema JW, Kähönen M, Kors JA, Lambiase PD, Launer LJ, Li M, Linneberg A, Nelson CP, Pedersen O, Perez M, Peters A, Polasek O, Psaty BM, Raitakari OT, Rice KM, Rotter JI, Sinner MF, Soliman EZ, Spector TD, Strauch K, Thorsteinsdottir U, Tinker A, Trompet S, Uitterlinden A, Vaartjes I, van der Meer P, Völker U, Völzke H, Waldenberger M, Wilson JG, Xie Z, Asselbergs FW, Dörr M, van Duijn CM, Gasparini P, Gudbjartsson DF, Gudnason V, Hansen T, Kääb S,
Background: Genome-wide association studies conducted on QRS duration, an electrocardiographic measurement associated with heart failure and sudden cardiac death, have led to novel biological insights into cardiac function. However, the variants identified fall predominantly in non-coding regions and their underlying mechanisms remain unclear. Results: Here, we identify putative functional coding variation associated with changes in the QRS interval duration by combining Illumina HumanExome Bead...
Abstract
Cited 4 times since 2018 (0.6 per year)
source: EuropePMC
Heart rhythm,
Volume 15, Issue 12, 12 2 2018, Pages 1816-1822
Impact of atrial fibrillation on improvement of functional mitral regurgitation in cardiac resynchronization therapy.
van der Bijl P, Vo NM, Leung M, Ajmone Marsan N, Delgado V, Stone GW, Bax JJ
Background: Functional mitral regurgitation (FMR) and atrial fibrillation (AF) are frequent heart failure (HF) complications. Cardiac resynchronization therapy (CRT) can improve FMR; however, little is known about the influence of AF on FMR improvement. Objective: The purpose of this study was to investigate the mechanisms and impact of baseline AF on FMR improvement after CRT. Methods: CRT recipients with HF, AF, or sinus rhythm (SR) at baseline with moderate or severe FMR, were included from a...
Abstract
Cited 6 times since 2018 (0.9 per year)
source: EuropePMC
Journal of periodontal research,
Volume 53, Issue 5, 4 1 2018, Pages 916-923
Matrix metalloproteinase-7 in periodontitis with type 2 diabetes mellitus.
Zeidán-Chuliá F, Yilmaz D, Häkkinen L, Könönen E, Neves de Oliveira BH, Güncü G, Uitto VJ, Caglayan F, Gürsoy UK
Background and objective: Elevated levels of matrix metalloproteinase-7 (MMP7) have been observed in serum samples of subjects with type 2 diabetes mellitus (T2DM) and in gingival tissues of subjects with periodontitis. The aim of the present study was to collect in vivo and in silico evidence on the role of MMP7 in the interplay between T2DM and generalized periodontitis (GP). Material and methods: The extent of MMP7 expression and localization were immunohistochemically analyzed in gingival ti...
Abstract
Cited 33 times since 2018 (4.9 per year)
source: EuropePMC
Applied and environmental microbiology,
Volume 84, Issue 14, 2 1 2018, Pages e00309-18
Human-Associated Lachnospiraceae Genetic Markers Improve Detection of Fecal Pollution Sources in Urban Waters.
Feng S, Bootsma M, McLellan SL
The human microbiome contains many organisms that could potentially be used as indicators of human fecal pollution. Here we report the development of two novel human-associated genetic marker assays that target organisms within the family Lachnospiraceae Next-generation sequencing of the V6 region of the 16S rRNA gene from sewage and animal stool samples identified 40 human-associated marker candidates with a robust signal in sewage and low or no occurrence in samples from nonhuman hosts. Two we...
Abstract
Cited 221 times since 2018 (32.9 per year)
source: EuropePMC
JAMA cardiology,
Volume 3, Issue 7, 1 1 2018, Pages 619-627
Association of LPA Variants With Risk of Coronary Disease and the Implications for Lipoprotein(a)-Lowering Therapies: A Mendelian Randomization Analysis.
Burgess S, Ference BA, Staley JR, Freitag DF, Mason AM, Nielsen SF, Willeit P, Young R, Surendran P, Karthikeyan S, Bolton TR, Peters JE, Kamstrup PR, Tybjærg-Hansen A, Benn M, Langsted A, Schnohr P, Vedel-Krogh S, Kobylecki CJ, Ford I, Packard C, Trompet S, Jukema JW, Sattar N, Di Angelantonio E, Saleheen D, Howson JMM, Nordestgaard BG, Butterworth AS, Danesh J, European Prospective Investigation Into Cancer and Nutrition–Cardiovascular Disease (EPIC-CVD) Consortium
Importance: Human genetic studies have indicated that plasma lipoprotein(a) (Lp[a]) is causally associated with the risk of coronary heart disease (CHD), but randomized trials of several therapies that reduce Lp(a) levels by 25% to 35% have not provided any evidence that lowering Lp(a) level reduces CHD risk. Objective: To estimate the magnitude of the change in plasma Lp(a) levels needed to have the same evidence of an association with CHD risk as a 38.67-mg/dL (ie, 1-mmol/L) change in low-dens...
Abstract
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery,
Volume 54, Issue 1, 1 1 2018, Pages 199
Mitral valve infective endocarditis: putting the puzzle pieces together.
Tomšic A, Klautz RJM, Palmen M
Abstract
Heart, lung & circulation,
Volume 27, Issue 7, 1 1 2018, Pages 782-784
Lessons from an International Bicuspid Aortic Valve Disease Registry: the Raphe and Beyond.
Ng ACT, Delgado V, Kong WKF, Bax JJ
Abstract
Cited 43 times since 2018 (6.4 per year)
source: EuropePMC
Circulation. Cardiovascular imaging,
Volume 11, Issue 7, 1 1 2018, Pages e007562
Quantification of Coronary Atherosclerosis in the Assessment of Coronary Artery Disease.
Lee SE, Sung JM, Rizvi A, Lin FY, Kumar A, Hadamitzky M, Kim YJ, Conte E, Andreini D, Pontone G, Budoff MJ, Gottlieb I, Lee BK, Chun EJ, Cademartiri F, Maffei E, Marques H, Leipsic JA, Shin S, Hyun Choi J, Chinnaiyan K, Raff G, Virmani R, Samady H, Stone PH, Berman DS, Narula J, Shaw LJ, Bax JJ, Min JK, Chang HJ
Background: Diagnosis of coronary artery disease and management strategies have relied solely on the presence of diameter stenosis ≥50%. We assessed whether direct quantification of plaque burden (PB) and plaque characteristics assessed by coronary computed tomography angiography could provide additional value in terms of predicting rapid plaque progression. Methods and results: From a 13-center, 7-country prospective observational registry, 1345 patients (60.4±9.4 years old; 57.1% male) who und...
Abstract
JACC. Cardiovascular imaging,
Volume 11, Issue 7, 1 1 2018, Pages 984-986
Will Cardiac Magnetic Resonance Change the Management of Severe Aortic Stenosis Patients?
Delgado V, Bax JJ
Abstract
Cited 5 times since 2018 (0.7 per year)
source: EuropePMC
European heart journal,
Volume 39, Issue 27, 1 1 2018, Pages 2600-2601
New prospects for PCSK9 inhibition?
Landmesser U, Chapman MJ, Stock JK, Amarenco P, Belch JJF, Borén J, Farnier M, Ference BA, Gielen S, Graham I, Grobbee DE, Hovingh GK, Lüscher TF, Piepoli MF, Ray KK, Ray KK, Stroes ES, Wiklund O, Windecker S, Zamorano JL, Pinto F, Tokgözoglu L, Bax JJ, Catapano AL, European Society of Cardiology/European Atherosclerosis Society Task Force
Abstract
