6173 results
JACC. Advances,
Volume 4, Issue 3, 26 4 2025, Pages 101633
Developing a Systematic Approach for the Implementation of Medical Extended Reality Learning Modules in Cardiothoracic Health Care: Recommendations From an International Expert Group.
Mahtab EAF, Max SA, Braun J, Regeer MV, Kaufman B, Dunning J, Bibleraaj B, Andreas M, Rodríguez Lecoq R, Klinceva M, Rosalia R, Lorusso R, Bruining N, Egorova AD
Extended reality (XR) modalities in health care are quickly evolving. There is a lack of systematically described developmental process and the "how to" execute a business-case guidance. This article formulates a systematic approach on the technical developmental steps and generation of business-case to guide the iterative development of an XR tool. An international expert group was established and several available frameworks related to entrepreneurship and business-case development w...
Abstract
STAR protocols,
Volume 6, Issue 1, 26 4 2025, Pages 103679
Massive expansion and cryopreservation of functional human induced pluripotent stem cell-derived cardiomyocytes.
Maas RGC, Lee S, Harakalova M, Snijders Blok CJB, Goodyer WR, Hjortnaes J, Doevendans PAFM, Van Laake LW, van der Velden J, Asselbergs FW, Wu JC, Sluijter JPG, Wu SM, Buikema JW
Abstract
PloS one,
Volume 20, Issue 2, 26 4 2025, Pages e0317826
The value of vector ECG in predicting residual pulmonary hypertension in CTEPH patients after pulmonary endarterectomy.
Luijten D, Rodenburg T, Bogaard HJ, Kianzad A, Ruigrok D, Croon P, Smeele P, Vliegen HW, Vonk Noordegraaf A, Meijboom LJ, Klok FA
Introduction: Right heart catheterization (RHC) is the diagnostic standard for establishing residual pulmonary hypertension (PH) after pulmonary endarterectomy (PEA) in patients with chronic thromboembolic pulmonary hypertension (CTEPH). A potential non-invasive alternative diagnostic test could be electrocardiography (ECG)-derived ventricular gradient optimized for right ventricular pressure overload (VG-RVPO). Methods: We studied 66 CTEPH patients who underwent PEA. A subgroup of 20 patients a...
Abstract
European heart journal. Cardiovascular Imaging,
24 4 2025, Pages jeaf063
Mitral Valve Stretched to its Limit: A Case of an Aborted Sudden Cardiac Death with Extensive Fibrotic Ventricular Remodeling.
van Rosendael PJ, Biesbroek PS, Meijs TA, Gotte MJW, Hopman LHGA
Abstract
JACC. Clinical electrophysiology,
21 3 2025, Pages S2405-500X(25)00066-0
The Relevance of the Type of Ventricular Arrhythmia in Titin-Related Dilated Cardiomyopathy: A Multicenter Study.
Ebert M, de Riva M, Wijnmaalen AP, Barge-Schaapveld DQCM, Bootsma M, Hoogendoorn J, Husser D, van Tintelen JP, Jongbloed JDH, Richter S, Berruezo A, Hindricks G, Stevenson WG, Zeppenfeld K
Background: Truncating titin variants (TTNtvs) are the most prevalent cause of inherited dilated cardiomyopathy. Occurrence of different ventricular arrhythmia (VA) subtypes, including premature ventricular complexes (PVCs), nonsustained ventricular tachycardia (NSVT), and sustained monomorphic VT (SMVT), has been reported. Objectives: The aim of this study was to analyze the prognostic relevance of distinct VA subtypes among TTNtv carriers and their underlying arrhythmogenic substrates. Methods...
Abstract
Journal of cardiothoracic and vascular anesthesia,
21 3 2025, Pages S1053-0770(25)00144-2
Vasoplegia in Cardiac Surgery: A Systematic Review and Meta-analysis of Current Definitions and Their Influence on Clinical Outcomes.
Papazisi O, van der Schoot MM, Berendsen RR, Arbous SM, le Cessie S, Dekkers OM, Klautz RJM, Marczin N, Palmen M, de Waal EEC
Objectives: To identify differences in the reported vasoplegia incidence, intensive care unit (ICU) length of stay (LOS), and 30-day mortality rates as influenced by different vasoplegia definitions used in cardiac surgery studies. Design: A systematic review was performed covering the period 1977 to 2023 using PubMed/MEDLINE, Embase, Web of Science, Cochrane Library, and Emcare and a meta-analysis (PROSPERO: CRD42021258328) was performed. Setting and participants: One hundred studies defining v...
Abstract
Circulation. Arrhythmia and electrophysiology,
Volume 18, Issue 3, 20 3 2025, Pages e013099
Characteristics of Patients With the Arrhythmogenic Mitral Valve Prolapse Syndrome and Sudden Cardiac Arrest and Sustained Ventricular Arrhythmias.
Chakrabarti A, Giudicessi JR, Ezzeddine FM, Delling FN, Dixit S, Lee YJ, Muser D, Magnani S, Van Wijngaarden A, Ajmone Marsan N, Miller MA, Gandhi J, Trivieri MG, Font J, Martins R, McCaffrey JA, Santangeli P, Marchlinski FE, Chapagain H, Mathew D, Kancharla K, Syed FF, Abid A, Cerbin L, Tzou WS, Garg L, Della Rocca DG, Natale A, Mohanty S, Sheldon SH, Kuo L, Haugaa KH, Aabel EW, Enriquez A, Maeda S, Deshmukh A, Ghannam M, Bogun F, Ackerman MJ, Liang JJ
Background: Patients with arrhythmogenic mitral valve prolapse syndrome are at increased risk for life-threatening ventricular arrhythmias, but studies have been limited by small sample sizes. We sought to assemble an international arrhythmogenic mitral valve prolapse syndrome registry to delineate the clinical, imaging, and treatment characteristics of patients with arrhythmogenic mitral valve prolapse syndrome who survived sudden cardiac arrest (SCA) or had sustained ventricular tachycardia (V...
Abstract
Journal of cardiovascular development and disease,
Volume 12, Issue 2, 18 3 2025, Pages 78
Beyond Survival: Assessing Quality of Life, Activity Level, and Ethnic Diversity in Aortic Dissection Survivors.
Bacour N, van Erp O, Grewal S, Tirpan AU, Eberl S, Yeung KK, Balm R, Verwoert GC, Driessen AHG, Klautz RJM, Grewal N
Background: An acute aortic dissection (AAD) is a highly lethal condition that demands immediate medical intervention. Survivors often face significant long-term challenges. While immediate survival remains a critical focus in acute care settings, little is known about long-term results, especially with regard to activity levels, post-operative quality of life, and the impact of cultural and ethnic characteristics on recovery. Using data from the Dutch National Aortic Dissection Survivor's...
Abstract
The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland,
Volume 23, Issue 2, 18 3 2025, Pages 78-86
Surgeon personality diversity across generations and subspecialties.
Sier VQ, Schmitz RF, Wertenbroek RWAM, Schepers A, van der Vorst JR, SUPER Collaborators
Background: Traditional exploration of surgical professionals' personality traits focuses on general characteristics at the domain-level of the five-factor model. Personality has been related to clinically-relevant areas such as clinical decision-making and team effectiveness, yet there is limited insight in the personality of surgeons at the facet-level of the Big Five. Here, we performed a large-scale study examining domain- and facet-variations of personality in four surgical generations...
Abstract
The Journal of thoracic and cardiovascular surgery,
17 3 2025, Pages S0022-5223(25)00120-5
Valve-sparing aortic root replacement in bicuspid aortic valves-the reimplantation technique: A multicenter study.
Arabkhani B, Boodhwani M, De Paulis R, Chen EP, Koolbergen D, Mastrobuoni S, Aphram G, Salica A, Jahanyar J, El Khoury G, de Kerchove L
Objective: Reported outcomes in patients with bicuspid aortic valves (BAVs) undergoing valve-sparing aortic root replacement (VSRR) are scarce. This study aims to evaluate outcomes in patients with BAV using the reimplantation (David) technique. Methods: Consecutive adult patients with BAV, aortic root aneurysm, and/or aortic valve insufficiency (AI) undergoing VSRR (reimplantation) were included from 5 centers experienced in reimplantation procedures. Patients were subcategorized into 2 groups...
Abstract
Open heart,
Volume 12, Issue 1, 17 3 2025, Pages e002846
Clinical use and impact of mechanical circulatory support for myocardial infarction-related cardiogenic shock in the Netherlands: a registry-based propensity-matched analysis.
Bogerd M, Griffioen AM, Bunge JJH, Peters EJ, Ten Berg S, Timmermans MJC, Kraaijeveld AO, Lipsic E, Otterspoor LC, Bleeker G, Montero-Cabezas JM, Sjauw KD, Meuwissen M, Dubois EA, van Geuns RM, Henriques JPS, PCI Registration Committee of the Netherlands Heart Registration
Background: Despite limited beneficial evidence, mechanical circulatory support (MCS) is commonly used in patients with acute myocardial infarction-related cardiogenic shock (AMI-CS). In this Dutch registry, we investigated MCS usage, associated patient characteristics and clinical outcomes. Methods: This real-world, multicentre registry included CS patients undergoing percutaneous coronary intervention between 2017 and 2021 in 14 Dutch hospitals. The impact on clinical outcomes was analysed aft...
Abstract
European journal of preventive cardiology,
8 2 2025, Pages zwaf067
Apolipoprotein C3 and risk of cardiovascular events and death in patients on optimized statin treatment after recent acute coronary syndrome.
Schwartz GG, Szarek M, Reijnders E, Jukema JW, Bhatt DL, Bittner VA, Fazio S, Garon G, Goodman SG, Harrington RA, White HD, Ruhaak LR, Stevanovic I, Cobbaert CM, Steg PG
Aims: Apolipoprotein (Apo) C3 has been associated with incident coronary heart disease and major adverse cardiovascular events (MACE). Whether ApoC3 levels predict risk in patients with acute coronary syndrome (ACS) on optimized statin treatment is unknown. Methods: ApoC3 was measured by mass spectrometry at baseline (n=11,956) and after 4 months' treatment (M4; n=11 176) with alirocumab or placebo in the ODYSSEY OUTCOMES trial. Patients with fasting triglycerides >400 mg/dL were exclude...
Abstract
Environmental monitoring and assessment,
Volume 197, Issue 3, 7 1 2025, Pages 252
Investigating the effects of local climate zones on land surface temperature using spectral indices via linear regression model: a seasonal study of Sapanca Lake.
Isinkaralar O, Yeboah E, Isinkaralar K, Sarfo I, Öztürk S, Yilmaz D, Bojago E
The formation of urban heat islands is a widespread issue in cities. However, the impact of spectral indices on land surface temperature (LST) with various urban forms, climates, and functions has not been sufficiently examined. Currently, the prevalent method for analyzing complex urban areas is the classification of local climate zones (LCZs). In this study, we aim to explore the urban thermal environment by utilizing GIS-based spatial analyses and statistical methods. We also examine LCZs and...
Abstract
The Pediatric infectious disease journal,
Volume 44, Issue 5, 5 1 2025, Pages e189-e190
Is Rhinovirus More Aggressive in Children This Season?
Özdem Alataş Ş, Elvan Tüz A, Kuş S, Aslan Saritaş Ü, Koçar S, Yilmaz D
Abstract
European heart journal. Cardiovascular Imaging,
4 1 2025, Pages jeaf045
The Reversibility of Cardiac Damage After Transcatheter Aortic Valve Implantation and Short-Term Outcomes in a Real-World Setting.
Myagmardorj R, Fortuni F, Généreux P, Nabeta T, Stassen J, Galloo X, Meucci MC, Butcher S, van der Kley F, Cohen DJ, Clavel MA, Pibarot P, Leon MB, Regeer MV, Delgado V, Ajmone Marsan N, Bax JJ
Aims: This study aims to assess the changes in cardiac damage stage in a real-world cohort of patients undergoing transcatheter aortic valve implantation (TAVI) and to investigate the prognostic value of cardiac damage stage evolution. Methods and results: Patients with severe AS undergoing TAVI were retrospectively analyzed. A 5-stage system based on the presence and extent of cardiac damage assessed by echocardiography was applied before and 6 months after TAVI. Multivariable Cox regression an...
Abstract
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology,
Volume 55, Issue 3, 4 1 2025, Pages 260-263
Increased Levels of Inflammatory Proteins, Including TARC/CCL17, in Skin of AD Patients During JAK Inhibitor Treatment.
Boesjes CM, van der Gang LF, Bakker DS, den Hartog Jager CF, de Graaf M, de Bruin-Weller MS, van Wijk F, Knol EF
Abstract
Journal of lipid research,
Volume 66, Issue 3, 3 1 2025, Pages 100753
Efficacy of a novel PCSK9 inhibitory peptide alone and with evinacumab in a mouse model of atherosclerosis.
Inia JA, van Nieuwkoop-van Straalen A, Jukema JW, Rolin B, Staarup EM, Mogensen CK, Princen HMG, van den Hoek AM
Atherosclerosis is the major cause of cardiovascular disease. This study evaluated the effect of lipid lowering using a novel peptide inhibiting proprotein convertase subtilisin/kexin type 9 (PCSK9) and a monoclonal antibody against angiopoietin-like 3 (evinacumab), either alone or in combination in APOE∗3-Leiden.CETP mice fed a Western diet. Effects on body weight, plasma lipids, atherosclerotic lesion size, severity, composition, and morphology were assessed. Treatment with PCSK9 inhibitory pe...
Abstract
Family practice,
Volume 42, Issue 2, 1 1 2025, Pages cmae045
The effect and implementation of the COVID Box, a remote patient monitoring system for patients with a COVID-19 infection in primary care: a matched cohort study.
van Hattem NE, Mijnsbergen NJ, van Os HJA, Mertens BA, Eekhof JAH, Chavannes NH, Atsma DE, Bonten TN
At the onset of the COVID-19 pandemic, the pressure on hospitals increased tremendously. To alleviate this pressure, a remote patient monitoring system called the COVID Box was developed and implemented in primary care. The aim was to assess whether the COVID Box in primary care could reduce emergency department (ED) referrals due to a COVID-19 infection. A matched cohort study was performed between December 2020 and June 2021. Patients with a COVID-19 infection in need of intensive monitoring b...
Abstract
European journal of endocrinology,
Volume 192, Issue 2, 1 1 2025, Pages S1-S14
The effect of first intervention on cardiac parameters in patients with acromegaly: a systematic review.
Huynh KA, Al-Gully J, Montero-Cabezas JM, Scheffers LE, Verstegen MJT, Biermasz NR, Coopmans EC
Objective: Cardiovascular disease in acromegaly patients remains a major cause of morbidity and all-cause mortality. This systematic review investigates the effect of the first growth hormone-lowering intervention on cardiac parameters. Design: Systematic review. Methods: Studies evaluating cardiac parameters following the first intervention in acromegaly published up to February, 25, 2022 were included in this systematic review. Risk of bias was assessed using a modified Newcastle-Ottawa Scale...
Abstract
Cited 1 times since 2025 (4.7 per year)
source: EuropePMC
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology,
Volume 27, Issue 2, 1 1 2025, Pages euaf003
Evoked delayed potential ablation for post-myocardial infarction ventricular tachycardia: results from a large prospective multicentre study.
de Riva M, Evertz R, Lukac P, Dekker LRC, Blaauw Y, Ter Bekke RMA, Kimura Y, Beukema RJ, Ouss A, Mulder BA, Vernooy K, Wijnmaalen AP, Zeppenfeld K
Aims: The optimal substrate ablation approach for post-myocardial infarction (MI) ventricular tachycardia (VT) is unknown. Proposed ablation targets are prone to individual interpretation making the ablation outcome potentially operator dependent. Evoked delayed potentials (EDPs) are a well-defined target. Evoked delayed potential ablation was effective in preventing post-MI VT recurrence in a prior study. The aims of this study were to assess long-term outcomes of EDP ablation in a large multic...
Abstract
