Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6125 results
Cited 44 times since 2004 (2.1 per year) source: EuropePMC
Current opinion in lipidology, Volume 15, Issue 4, 1 1 2004, Pages 393-398 CETP gene variation: relation to lipid parameters and cardiovascular risk. Boekholdt SM, Kuivenhoven JA, Hovingh GK, Jukema JW, Kastelein JJ, van Tol A
Purpose of review: Over the past decade lowering of low-density lipoprotein-cholesterol levels has been established as the foundation for preventing coronary artery disease, but substantial additional risk reduction remains to be gained by modifying risk factors other than low-density lipoprotein-cholesterol. Raising high-density lipoprotein-cholesterol levels by inhibiting activity of the cholesteryl ester transfer protein (CETP) is a prime target. Research on naturally occurring variants in th... Abstract
Cited 3 times since 2004 (0.1 per year) source: EuropePMC
Radiology, Volume 232, Issue 3, 23 4 2004, Pages 915-920 Blood flow in coronary artery bypass vein grafts: volume versus velocity at cardiovascular MR imaging. Salm LP, Langerak SE, Vliegen HW, Jukema JW, Bax JJ, Zwinderman AH, van der Wall EE, de Roos A, Lamb HJ
Forty-nine patients with previous bypass surgery underwent coronary angiography and cardiovascular magnetic resonance (MR) imaging of single-vein bypass grafts. Volume flow and velocity analyses were performed and compared on MR velocity maps. Bland-Altman analysis showed close agreement between the two types of analysis. Comparison of areas under the receiver operating characteristic curve revealed no significant differences between the analyses for detection of stenoses of 70% or greater. Diag... Abstract
Cited 29 times since 2004 (1.4 per year) source: EuropePMC
Anatomy and embryology, Volume 208, Issue 5, 10 2 2004, Pages 389-393 The neural crest is contiguous with the cardiac conduction system in the mouse embryo: a role in induction? Poelmann RE, Jongbloed MR, Molin DG, Fekkes ML, Wang Z, Fishman GI, Doetschman T, Azhar M, Gittenberger-de Groot AC
In this study we present data on the spatial relationship between neural crest-derived cells (NCC) and the specialized cardiac conduction system (CCS) in the developing murine heart. Using Wnt1-Cre/R26R conditional reporter mice that express beta-galactosidase from ROSA26 upon Cre-mediated recombination, two populations of NCC are seen: one migrates through the arterial pole and contributes to the bundle branches, whereas the second population enters by way of the venous pole and provides cells... Abstract
Cited 44 times since 2004 (2.1 per year) source: EuropePMC
European heart journal, Volume 25, Issue 13, 1 1 2004, Pages 1163-1170 Current PTCA practice and clinical outcomes in The Netherlands: the real world in the pre-drug-eluting stent era. Agema WR, Monraats PS, Zwinderman AH, De Winter RJ, Tio RA, Doevendans PA, Waltenberger J, De Maat MP, Frants RR, Atsma DE, Van Der Laarse A, Van Der Wall EE, Jukema JW
Aims: To document the practice of interventional cardiology and the clinical restenosis rate, as well as the risk factors for clinical restenosis in an unselected population of patients in daily practice and to provide a perspective for the need of new devices such as drug-eluting stents. Methods and results: A total of 3177 consecutive patients, who underwent successful percutaneous transluminal coronary angioplasty (PTCA) in the Netherlands, were included. Patients with acute myocardial infarc... Abstract
Cited 25 times since 2004 (1.2 per year) source: EuropePMC
The American journal of cardiology, Volume 94, Issue 1, 1 1 2004, Pages 130-132 Effect of left ventricular remodeling after cardiac resynchronization therapy on frequency of ventricular arrhythmias. Kiès P, Bax JJ, Molhoek SG, Bleeker GB, Zeppenfeld K, Bootsma M, St John Sutton M, van Erven L, van der Wall EE, Schalij MJ
We evaluated whether cardiac resynchronization therapy affects the prevalence of ventricular tachycardia in relation to reverse remodeling in patients with end-stage heart failure. Clinical, echocardiographic, and implantable cardioverter-defibrillator (ICD) data of 17 patients with ICDs were obtained before and after they had received an upgrade to an ICD-cardiac resynchronization therapy device. Abstract
Cited 20 times since 2004 (1 per year) source: EuropePMC
The American journal of medicine, Volume 117, Issue 1, 1 1 2004, Pages 1-9 Long-term prognostic value of dobutamine stress echocardiography compared with myocardial perfusion scanning in patients unable to perform exercise tests. Schinkel AF, Bax JJ, Elhendy A, van Domburg RT, Valkema R, Vourvouri E, Bountioukos M, Rizzello V, Biagini E, Agricola E, Krenning EP, Simoons ML, Poldermans D
Purpose: To compare the long-term prognostic value of dobutamine stress echocardiography and dobutamine stress single photon emission computed tomography (SPECT) in patients unable to perform an exercise test. Methods: We assessed the prognostic value of dobutamine stress technetium 99m ((99m)Tc)-sestamibi SPECT and dobutamine stress echocardiography in 301 patients who were unable to perform exercise tests. Outcomes during a mean (+/- SD) follow-up of 7.3 +/- 2.8 years were overall death, cardi... Abstract
Cited 12 times since 2004 (0.6 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 17, Issue 7, 1 1 2004, Pages 739-743 Prognostic value of dobutamine stress echocardiography in patients with normal left ventricular systolic function. Elhendy A, Schinkel AF, Bax JJ, Van Domburg RT, Poldermans D
Background: Patients with normal left ventricular systolic function are considered to be at a relatively low risk for cardiac events. There are scarce data regarding association of ischemia on stress imaging techniques with outcome in these patients. Objectives: We sought to assess the prognostic significance of dobutamine-induced myocardial ischemia for patients with normal left ventricular systolic function. Methods: We studied 528 patients with normal baseline left ventricular systolic functi... Abstract
Cited 247 times since 2004 (11.9 per year) source: EuropePMC
Journal of the American College of Cardiology, Volume 44, Issue 1, 1 1 2004, Pages 1-9 Echocardiographic evaluation of cardiac resynchronization therapy: ready for routine clinical use? A critical appraisal. Bax JJ, Ansalone G, Breithardt OA, Derumeaux G, Leclercq C, Schalij MJ, Sogaard P, St John Sutton M, Nihoyannopoulos P
Cardiac resynchronization therapy (CRT) has been proposed as an alternative treatment in patients with severe, drug-refractory heart failure. The clinical results are promising, and improvement in symptoms, exercise capacity, and systolic left ventricular (LV) function have been demonstrated after CRT, accompanied by a reduction in hospitalization and a superior survival as compared with optimized medical therapy alone. However, 20% to 30% of patients do not respond to CRT. Currently, patients a... Abstract
Cited 11 times since 2004 (0.5 per year) source: EuropePMC
Pediatric hematology and oncology, Volume 21, Issue 5, 1 1 2004, Pages 403-410 Safety profiles of Fe2+ and Fe3+ oral preparations in the treatment of iron deficiency anemia in children. Kavakli K, Yilmaz D, Cetinkaya B, Balkan C, Sözmen EY, Sağin FG
The major purpose of this study was to compare the oxidant-related toxicities of the different oral iron preparations in children with iron deficiency anemia (IDA); the second aim was to investigate the side effects of iron preparations. Seventy-two children with IDA were randomly included in the Fe(2+) group (n = 39) or the Fe(3+) group (n = 33). Some oxidizable substrates (erythrocytes malondialdehyde (MDA), urine 8-isoprostane, and basal and Cu-stimulated-oxidized LDL and antioxidant enzyme (... Abstract
Cited 12 times since 2004 (0.6 per year) source: EuropePMC
European journal of pharmacology, Volume 493, Issue 1-3, 1 1 2004, Pages 161-165 Angiotensin deficiency in mice leads to dilated cardiomyopathy. Walther T, Steendijk P, Westermann D, Hohmann C, Schulze K, Heringer-Walther S, Schultheiss HP, Tschöpe C
To explore the role of angiotensin II, we assessed hemodynamics and cardiac function in angiotensinogen-deficient mice in comparison to wild-type animals. Left ventricular end-diastolic diameter and wall thickness were evaluated by echocardiography and systolic and diastolic left ventricular function by pressure-volume relations using a micro-conductance catheter. Compared to wild-type animals, the angiotensinogen-deficient mice were hypotensive and showed impaired systolic function. The hearts... Abstract
Cited 27 times since 2004 (1.3 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 90, Issue 6, 1 1 2004, Pages 678-684 Cardiovascular response to physical exercise in adult patients after atrial correction for transposition of the great arteries assessed with magnetic resonance imaging. Roest AA, Lamb HJ, van der Wall EE, Vliegen HW, van den Aardweg JG, Kunz P, de Roos A, Helbing WA
Objective: To assess with magnetic resonance imaging (MRI) cardiovascular function in response to exercise in patients after atrial correction of transposition of the great arteries (TGA). Methods: Cardiac function at rest and during submaximal exercise was assessed with MRI in 27 patients with TGA (mean (SD) age 26 (5) years) late (23 (2) years) after atrial correction and in 14 control participants (25 (5) years old). Results: At rest, only right ventricular ejection fraction was significantly... Abstract
Cited 45 times since 2004 (2.2 per year) source: EuropePMC
The American journal of cardiology, Volume 93, Issue 12, 1 1 2004, Pages 1461-1464 Head-to-head comparison between contrast-enhanced magnetic resonance imaging and dobutamine magnetic resonance imaging in men with ischemic cardiomyopathy. Kaandorp TA, Bax JJ, Schuijf JD, Viergever EP, van Der Wall EE, de Roos A, Lamb HJ
Contrast-enhanced magnetic resonance imaging (MRI) can predict functional recovery after revascularization. Segments with small, subendocardial scars have a large likelihood of recovery, and segments with transmural infarction have a small likelihood of recovery. Segments with an intermediate extent of infarction have an intermediate likelihood of recovery, and therefore, additional information is needed. Accordingly, the transmurality of infarction on contrast-enhanced MRI was compared with low... Abstract
Cited 4 times since 2004 (0.2 per year) source: EuropePMC
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, Volume 5, Issue 3, 1 1 2004, Pages 231-236 Aortic valve regurgitation due to cusp aneurysm: a case report. Scholte AJ, Agema WR, Poldermans D, Somer ST, Holman ER, van der Wall EE, Bax JJ
Two-dimensional echocardiography is a valuable tool in visualizing and monitoring aortic valve and root abnormalities. We present a rare case of a patient with massive aortic regurgitation due to cusp aneurysm, which was accurately diagnosed by echocardiography and treated by valve replacement. A complicated course with recurrent aneurysms of the aortic wall after aortic valve replacement was remarkable in this case. Although different possible etiologies could not be determined, endocarditis an... Abstract
Cited 1 times since 2004 (0 per year) source: EuropePMC
The Annals of thoracic surgery, Volume 77, Issue 6, 1 1 2004, Pages 2262-3; author reply 2263 Use of autologous arterial patches for tracheal reconstruction in young infants. Hazekamp MG, Nijdam N
Cited 54 times since 2004 (2.6 per year) source: EuropePMC
Circulation research, Volume 95, Issue 1, 20 3 2004, Pages 58-66 Vascular endothelial growth factor overexpression in ischemic skeletal muscle enhances myoglobin expression in vivo. van Weel V, Deckers MM, Grimbergen JM, van Leuven KJ, Lardenoye JH, Schlingemann RO, van Nieuw Amerongen GP, van Bockel JH, van Hinsbergh VW, Quax PH
Therapeutic angiogenesis using vascular endothelial growth factor (VEGF) is considered a promising new therapy for patients with arterial obstructive disease. Clinical improvements observed consist of improved muscle function and regression of rest pain or angina. However, direct evidence for improved vascularization, as evaluated by angiography, is weak. In this study, we report an angiogenesis-independent effect of VEGF on ischemic skeletal muscle, ie, upregulation of myoglobin after VEGF trea... Abstract
Cited 3 times since 2004 (0.1 per year) source: EuropePMC
Intensive care medicine, Volume 30, Issue 7, 4 1 2004, Pages 1370-1376 Transcardiac conductance for continuous measurement of left ventricular volume: validation vs. angiography in patients. Staal EM, Baan J, Jukema JW, van der Wall EE, Steendijk P
Objective: To test the feasibility of the transcardiac conductance (TCC) method for continuous, on-line measurement of absolute left ventricular (LV) volume and to validate the method by comparison with biplane angiography. Design and setting: Prospective clinical feasibility and validation study in a cardiac catheterization laboratory in a university hospital. Patients and interventions: Ten patients scheduled for electrophysiological studies ( n=5), percutaneous transluminal coronary angioplas... Abstract
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 12, Issue 5, 1 1 2004, Pages 255-256 Recommendations for pacemaker implantation for the treatment of atrial tachyarrhythmias and resynchronisation therapy for heart failure. Wijffels MC, Bootsma M, van Erven L, Zeppenfeld K, Schalij MJ, van Hemel NM
Cited 13 times since 2004 (0.6 per year) source: EuropePMC
Pathologie-biologie, Volume 52, Issue 4, 1 1 2004, Pages 186-195 Genetic predictive factors in restenosis. Monraats PS, R P Agema W, Jukema JW
Restenosis is still the main drawback of percutaneous transluminal coronary angioplasty (PTCA). It is thought to be a multifactorial process where recoil of the vessel, neointimal proliferation and thrombus formation are thought to play a role. Until now it has proven difficult to predict restenosis on clinical and procedural grounds, however, genetic epidemiology might provide more insights. In this review several genetic variables, i.e. polymorphisms that were determined in relation to resteno... Abstract
Cited 12 times since 2004 (0.6 per year) source: EuropePMC
European journal of pharmacology, Volume 491, Issue 2-3, 1 1 2004, Pages 173-179 Hemodynamic characterization of left ventricular function in experimental coxsackieviral myocarditis: effects of carvedilol and metoprolol. Tschöpe C, Westermann D, Steendijk P, Noutsias M, Rutschow S, Weitz A, Schwimmbeck PL, Schultheiss HP, Pauschinger M
Background: Carvedilol, a vasodilating nonselective beta-adrenoceptor antagonist, but not metoprolol, a selective beta1-adrenoceptor antagonist, has been shown to increase the production of cardiac antiinflammatory cytokines in experimental myocarditis. However, the hemodynamic consequences of these differences had not been investigated until today. Therefore, we determined the effects of carvedilol and metoprolol on left ventricular function in a murine model of coxsackievirus B3 (CVB3)-induced... Abstract
Cited 1 times since 2004 (0 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 12, Issue 5, 1 1 2004, Pages 214-222 Recommendations and cardiological evaluation of athletes with arrhythmias: Part 2. Hoogsteen J, Bennekers JH, van der Wall EE, van Hemel NM, Wilde AA, Crijns HJ, Gorgels AP, Smeets JL, Hauer RN, Jordaens JL, Schalij MJ
Confronted with a competitive or recreational athlete, the physician has to discriminate between benign, paraphysiological and pathological arrhythmias. Benign arrhythmias do not represent a risk for SCD, nor do they induce haemodynamic consequences during athletic activities. These arrhythmias are not markers for heart disease. Paraphysiological arrhythmias are related to athletic performance. Long periods of endurance training induce changes in rhythm, conduction and repolarisation. These chan... Abstract