Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
9251 results
Cited 30 times since 2013 (2.4 per year) source: EuropePMC
Atherosclerosis, Volume 229, Issue 2, 1 1 2013, Pages 423-429 Abdominal adiposity largely explains associations between insulin resistance, hyperglycemia and subclinical atherosclerosis: the NEO study. Gast KB, Smit JW, den Heijer M, Middeldorp S, Rippe RC, le Cessie S, de Koning EJ, Jukema JW, Rabelink TJ, de Roos A, Rosendaal FR, de Mutsert R, NEO study group
Objective: The relative importance of insulin resistance and hyperglycemia to the development of atherosclerosis remains unclear. Furthermore, adiposity may be responsible for observed associations. Our aim was to study the relative contributions of adiposity, insulin resistance and hyperglycemia to subclinical atherosclerosis. Methods: In this cross-sectional analysis of the Netherlands Epidemiology of Obesity (NEO) study, a cohort of persons of 45-65 years, BMI, waist circumference (WC), fasti... Abstract
Cited 3 times since 2013 (0.2 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 21, Issue 6, 1 1 2013, Pages 266-267 NVVC/NHJ Durrer Prizes 2012. van der Wall EE, Schalij MJ, Umans VA
At the annual Spring Congress of the NVVC the Durrer prizes were awarded to the authors of the best original/review articles published in the year 2012, one paper being more basically-oriented and one paper being more clinically-oriented. This annual tradition exists already since the year 2006. Abstract
Cited 18 times since 2013 (1.5 per year) source: EuropePMC
Anesthesiology, Volume 118, Issue 6, 1 1 2013, Pages 1385-1394 Xenon and isoflurane reduce left ventricular remodeling after myocardial infarction in the rat. Roehl AB, Funcke S, Becker MM, Goetzenich A, Bleilevens C, Rossaint R, Steendijk P, Hein M
Background: Xenon and isoflurane are known to have cardioprotective properties. We tested the hypothesis that these anesthetics positively influence myocardial remodeling 28 days after experimental perioperative myocardial infarction and compared their effects. Methods: A total of 60 male Sprague-Dawley rats were subjected to 60 min of coronary artery occlusion and 120 min of reperfusion. Prior to ischemia, the animals were randomized for the different narcotic regimes (0.6 vol% isoflurane, 70 v... Abstract
Cited 4 times since 2013 (0.3 per year) source: EuropePMC
Archivos espanoles de urologia, Volume 66, Issue 5, 1 1 2013, Pages 432-439 The role of methylation in urological tumours. van der Heijden AG
Alterations in DNA methylation have been described in human cancer for more than thirty years now. Since the last decade DNA methylation gets more and more important in cancer research. In this review the different alterations of DNA methylation are discussed in testicular germ cell tumours, Wilms'tumours, renal cell carcinomas, urothelial cell carcinomas of the bladder and adenocarcinomas of the prostate. Eventually, the potential use in diagnostics, prognostics and therapy are discussed. Abstract
Cited 1 times since 2013 (0.1 per year) source: EuropePMC
The Behavioral and brain sciences, Volume 36, Issue 3, 1 1 2013, Pages 294-295 The cognitive economy: the probabilistic turn in psychology and human cognition. Kusev P, van Schaik P
According to the foundations of economic theory, agents have stable and coherent "global" preferences that guide their choices among alternatives. However, people are constrained by information-processing and memory limitations and hence have a propensity to avoid cognitive load. We propose that this in turn will encourage them to respond to "local" preferences and goals influenced by context and memory representations. Abstract
Cited 31 times since 2013 (2.5 per year) source: EuropePMC
British journal of clinical pharmacology, Volume 75, Issue 6, 1 1 2013, Pages 1506-1515 The Val158Met polymorphism of the COMT gene is associated with increased pain sensitivity in morphine-treated patients undergoing a painful procedure after cardiac surgery. Ahlers SJ, Elens LL, van Gulik L, van Schaik RH, van Dongen EP, Bruins P, Tibboel D, Knibbe CA
Aims: The catechol-O-methyltransferase (COMT) Val158Met polymorphism affected pain sensitivity of healthy volunteers upon application of experimental pain stimuli. The relevance of these findings in morphine-treated postoperative cardiac patients undergoing painful healthcare procedures is unknown; therefore, the aim of this study was to investigate whether the COMT Val158Met polymorphism increases pain sensitivity in morphine-treated patients undergoing an unavoidable painful routine procedure... Abstract
Cited 33 times since 2013 (2.7 per year) source: EuropePMC
British journal of clinical pharmacology, Volume 75, Issue 6, 1 1 2013, Pages 1545-1547 The CYP3A4*22 allele affects the predictive value of a pharmacogenetic algorithm predicting tacrolimus predose concentrations. Elens L, Hesselink DA, van Schaik RH, van Gelder T
Cited 16 times since 2013 (1.3 per year) source: EuropePMC
The Indian journal of medical research, Volume 137, Issue 6, 1 1 2013, Pages 1111-1120 Adaptation of heart to training: a comparative study using echocardiography & impedance cardiography in male & female athletes. Yilmaz DC, Buyukakilli B, Gurgul S, Rencuzogullari I
Background & objectives: Intensive regular physical exercise training is associated with a physiological changes in left ventricular (LV) morphology and functions. This cardiac remodeling observed in the athletes is associated with the specific haemodynamic requirements of the exercise undertaken. The main objective of this study is to evaluate the effect of endurance training on cardiac morphology, systolic and diastolic LV functions and haemodynamic parameters both in male and female athle... Abstract
Cited 9 times since 2013 (0.7 per year) source: EuropePMC
European journal of preventive cardiology, Volume 20, Issue 2 Suppl, 1 1 2013, Pages 8-12 Remote monitoring of patients with implanted devices: data exchange and integration. Van der Velde ET, Atsma DE, Foeken H, Witteman TA, Hoekstra WH
Background: Remote follow-up of implanted implantable cardioverter defibrillators (ICDs) may offer a solution to the problem of overcrowded outpatient clinics, and may also be effective in detecting clinical events early. Data obtained from remote follow up systems, as developed by all major device companies, are stored in a central database system, operated and owned by the device company. A problem now arises that the patient's clinical information is partly stored in the local electronic... Abstract
Cited 42 times since 2013 (3.4 per year) source: EuropePMC
American journal of physiology. Heart and circulatory physiology, Volume 305, Issue 3, 31 5 2013, Pages H354-64 Distinct loading conditions reveal various patterns of right ventricular adaptation. Borgdorff MA, Bartelds B, Dickinson MG, Steendijk P, de Vroomen M, Berger RM
Right ventricular (RV) failure due to chronically abnormal loading is a main determinant of outcome in pulmonary hypertension (PH) and congenital heart disease. However, distinct types of RV loading have been associated with different outcomes. To determine whether the adaptive RV response depends on loading type, we compared hemodynamics, exercise, and hypertrophy in models of pressure overload due to pulmonary artery banding (PAB), pressure overload due to PH, combined pressure and volume over... Abstract
Cited 24 times since 2013 (2 per year) source: EuropePMC
PloS one, Volume 8, Issue 5, 31 5 2013, Pages e65224 The Enterococcus faecium enterococcal biofilm regulator, EbrB, regulates the esp operon and is implicated in biofilm formation and intestinal colonization. Top J, Paganelli FL, Zhang X, van Schaik W, Leavis HL, van Luit-Asbroek M, van der Poll T, Leendertse M, Bonten MJ, Willems RJ
Nowadays, Enterococcus faecium is one of the leading nosocomial pathogens worldwide. Strains causing clinical infections or hospital outbreaks are enriched in the enterococcal surface protein (Esp) encoding ICEEfm1 mobile genetic element. Previous studies showed that Esp is involved in biofilm formation, endocarditis and urinary tract infections. In this study, we characterized the role of the putative AraC type of regulator (locus tag EfmE1162_2351), which we renamed ebrB and which is, based on... Abstract
Cited 24 times since 2013 (2 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 99, Issue 17, 30 5 2013, Pages 1244-1249 Gender-specific differences in clinical outcome of primary prevention implantable cardioverter defibrillator recipients. van der Heijden AC, Thijssen J, Borleffs CJ, van Rees JB, Höke U, van der Velde ET, van Erven L, Schalij MJ
Objective: To assess differences in clinical outcome of implantable cardioverter-defibrillator (ICD) treatment in men and women. Design: Prospective cohort study. Setting: University Medical Center. Patients: 1946 primary prevention ICD recipients (1528 (79%) men and 418 (21%) women). Patients with congenital heart disease were excluded for this analysis. Main outcome measures: All-cause mortality, ICD therapy (antitachycardia pacing and shock) and ICD shock. Results: During a median follow-up o... Abstract
Cited 3 times since 2013 (0.2 per year) source: EuropePMC
European journal of nuclear medicine and molecular imaging, Volume 40, Issue 8, 29 5 2013, Pages 1171-1180 Automated quantitative coronary computed tomography correlates of myocardial ischaemia on gated myocardial perfusion SPECT. de Graaf MA, El-Naggar HM, Boogers MJ, Veltman CE, Broersen A, Kitslaar PH, Dijkstra J, Kroft LJ, Al Younis I, Reiber JH, Bax JJ, Delgado V, Scholte AJ
Purpose: Automated software tools have permitted more comprehensive, robust and reproducible quantification of coronary stenosis, plaque burden and plaque location of coronary computed tomography angiography (CTA) data. The association between these quantitative CTA (QCT) parameters and the presence of myocardial ischaemia has not been explored. The aim of the present investigation was to evaluate the association between QCT parameters of coronary artery lesions and the presence of myocardial is... Abstract
Cited 74 times since 2013 (6 per year) source: EuropePMC
European urology, Volume 64, Issue 4, 25 4 2013, Pages 530-539 Screening for prostate cancer: results of the Rotterdam section of the European randomized study of screening for prostate cancer. Roobol MJ, Kranse R, Bangma CH, van Leenders AG, Blijenberg BG, van Schaik RH, Kirkels WJ, Otto SJ, van der Kwast TH, de Koning HJ, Schröder FH, ERSPC Rotterdam Study Group
Background: Evidence from randomized trials on the effects of screening for prostate cancer (PCa) on disease-specific mortality accumulates slowly with increasing follow-up. Objective: To assess data on PCa-specific mortality in the Rotterdam section of the European Randomized Study of Screening for Prostate Cancer (ERSPC) trial. Design, setting, and participants: A randomized controlled trial with randomization after signed, written informed consent (efficacy trial). In the period 1993-1999, a... Abstract
Cited 3 times since 2013 (0.2 per year) source: EuropePMC
European heart journal, Volume 34, Issue 31, 24 4 2013, Pages 2432-2435 View point: what should the future design of clinical imaging studies be? Gaemperli O, Lüscher TF, Bax JJ
Cited 5 times since 2013 (0.4 per year) source: Scopus
The American journal of cardiology, Volume 112, Issue 5, 24 4 2013, Pages 714-719 Mitral valve geometry and hemodynamics after surgical mitral valve annuloplasty and implications for percutaneous treatment of patients with recurrent mitral regurgitation. Al Amri I, Debonnaire P, Witkowski T, van der Kley F, Palmen M, de Weger A, Klautz RJ, Bax JJ, Schalij MJ, Ajmone Marsan N, Delgado V
The feasibility of transcatheter mitral valve therapy (edge-to-edge or valve-in-ring technique) in patients with significant mitral regurgitation (MR) recurrence after surgical restrictive mitral valve annuloplasty remains unknown. The aim of the present study was to investigate the eligibility for transcatheter mitral valve therapy of high-surgical-risk patients with significant MR recurrence after initial successful restrictive mitral valve annuloplasty. A total of 47 patients (age 67 ± 10 yea... Abstract
Cited 35 times since 2013 (2.8 per year) source: EuropePMC
Heart (British Cardiac Society), Volume 99, Issue 14, 23 4 2013, Pages 1018-1023 Suitability for subcutaneous defibrillator implantation: results based on data from routine clinical practice. de Bie MK, Thijssen J, van Rees JB, Putter H, van der Velde ET, Schalij MJ, van Erven L
Objective: To assess the proportion of current implantable cardioverter defibrillator (ICD) recipients who would be suitable for a subcutaneous lead ICD (S-ICD). Design: A retrospective cohort study. Setting: Tertiary care facility in the Netherlands. Patients: All patients who received a single- or dual-chamber ICD in the Leiden University Medical Center between 2002 and 2011. Patients with a pre-existent indication for cardiac pacing were excluded. Main outcome measure: Suitability for an S-IC... Abstract
Cited 85 times since 2013 (6.9 per year) source: EuropePMC
The British journal of surgery, Volume 100, Issue 8, 21 3 2013, Pages 1037-1044 Clinical trial of combined radio- and fluorescence-guided sentinel lymph node biopsy in breast cancer. Schaafsma BE, Verbeek FP, Rietbergen DD, van der Hiel B, van der Vorst JR, Liefers GJ, Frangioni JV, van de Velde CJ, van Leeuwen FW, Vahrmeijer AL
Background: Combining radioactive colloids and a near-infrared (NIR) fluorophore permits preoperative planning and intraoperative localization of deeply located sentinel lymph nodes (SLNs) with direct optical guidance by a single lymphatic tracer. The aim of this clinical trial was to evaluate and optimize a hybrid NIR fluorescence and radioactive tracer for SLN detection in patients with breast cancer. Methods: Patients with breast cancer undergoing SLN biopsy were enrolled. The day before surg... Abstract
Cited 37 times since 2013 (3 per year) source: EuropePMC
Basic & clinical pharmacology & toxicology, Volume 113, Issue 2, 20 3 2013, Pages 126-131 Sex difference in formation of propofol metabolites: a replication study. Choong E, Loryan I, Lindqvist M, Nordling Å, el Bouazzaoui S, van Schaik RH, Johansson I, Jakobsson J, Ingelman-Sundberg M
Women recover faster from propofol anaesthesia and have been described to have a higher incidence of awareness during surgery, compared to men - an effect that may be inherent in sex differences in propofol metabolism. In an observational study, 98 ASA I-II patients treated with continuous propofol infusion were recruited. The associations between sex and CYP2B6 and UGT1A9 polymorphisms with dose- and weight-adjusted area under the total plasma level time curves (AUC) for propofol, and its metab... Abstract
Cited 17 times since 2013 (1.4 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 45, Issue 1, 17 3 2013, Pages 83-89 Long-term tricuspid valve prosthesis-related complications in patients with congenital heart disease. van Slooten YJ, Freling HG, van Melle JP, Mulder BJ, Jongbloed MR, Ebels T, Voors AA, Pieper PG
Objectives: In patients with acquired valvar disease, morbidity and mortality rates after tricuspid valve replacement (TVR) are high. However, in adult patients with congenital heart disease, though data concerning outcome after TVR are scarce, even poorer results are suggested in patients with Ebstein anomaly. To investigate the applicability of these results to a broader array of congenital heart disease patients, we report the long-term follow-up of prosthesis-related complications, including... Abstract