9618 results
Cited 27 times since 2006 (1.4 per year)
source: EuropePMC
American heart journal,
Volume 152, Issue 5, 1 1 2006, Pages 975.e1-8
Aortic root dysfunctioning and its effect on left ventricular function in Ross procedure patients assessed with magnetic resonance imaging.
Grotenhuis HB, Westenberg JJ, Doornbos J, Kroft LJ, Schoof PH, Hazekamp MG, Vliegen HW, Ottenkamp J, de Roos A
Background: This study evaluated the diameters and distensibility of the aortic root as well as the degree of aortic regurgitation (AR) and its effect on left ventricular (LV) function in patients 8.2 +/- 3.1 years after they underwent the Ross procedure, with a comparison of these parameters between patients and matched healthy subjects. Methods: Eighteen Ross procedure patients (16 male patients, age [mean +/- SD] 19.2 +/- 3.8 years) and 18 matched healthy subjects (16 male patients, age [mean...
Abstract
Cited 33 times since 2006 (1.8 per year)
source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
Volume 47, Issue 11, 1 1 2006, Pages 1749-1755
A comparative regional analysis of coronary atherosclerosis and calcium score on multislice CT versus myocardial perfusion on SPECT.
Schuijf JD, Wijns W, Jukema JW, Decramer I, Atsma DE, de Roos A, Stokkel MP, Dibbets-Schneider P, van der Wall EE, Bax JJ
Unlabelled: For the noninvasive evaluation of coronary artery disease (CAD), both multislice CT and gated SPECT are available. How these 2 modalities relate, however, is yet unclear. The purpose of this study was to perform a head-to-head comparison of the results of multislice CT and gated SPECT on a regional basis (per vessel distribution territory) in patients with known or suspected CAD. Methods: One hundred forty patients underwent both multislice CT for coronary calcium scoring and coronar...
Abstract
Cited 24 times since 2006 (1.3 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 82, Issue 5, 1 1 2006, Pages 1721-1727
Beneficial hemodynamic and clinical effects of surgical ventricular restoration in patients with ischemic dilated cardiomyopathy.
Tulner SA, Bax JJ, Bleeker GB, Steendijk P, Klautz RJ, Holman ER, Schalij MJ, Dion RA, van der Wall EE
Background: Surgical ventricular restoration is increasingly applied in patients with ischemic dilated cardiomyopathy. Previous studies show promising results with regard to survival and clinical outcome. However, a comprehensive midterm analysis of this approach on left ventricular (LV) and right ventricular function is not yet available. We investigated biventricular function and clinical status at 6-month follow-up. Methods: We investigated the effects of surgical ventricular restoration on c...
Abstract
Cited 54 times since 2006 (2.9 per year)
source: EuropePMC
European radiology,
Volume 17, Issue 7, 27 4 2006, Pages 1700-1713
The use of perfusion CT for the evaluation of therapy combining AZD2171 with gefitinib in cancer patients.
Meijerink MR, van Cruijsen H, Hoekman K, Kater M, van Schaik C, van Waesberghe JH, Giaccone G, Manoliu RA
The purpose of this study was to determine the feasibility of dynamic contrast-enhanced perfusion CT (CTP) in evaluating the hemodynamic response of tumors in the chest and abdomen treated with a combination of AZD2171 and gefitinib. Thirteen patients were examined just before and every 4-6 weeks after starting therapy. Following intravenous injection of a contrast agent, dynamic image acquisition was obtained at the level of a selected tumor location. To calculate perfusion, the maximum-slope m...
Abstract
Cited 39 times since 2006 (2.1 per year)
source: EuropePMC
Heart (British Cardiac Society),
Volume 93, Issue 4, 25 4 2006, Pages 506-509
Long-term effect of pulmonary valve replacement on QRS duration in patients with corrected tetralogy of Fallot.
Oosterhof T, Vliegen HW, Meijboom FJ, Zwinderman AH, Bouma B, Mulder BJ
Objective: To analyse the long-term course of QRS duration after pulmonary valve replacement in patients with a previous correction for tetralogy of Fallot. Setting: Tertiary referral centres. Methods: In a retrospective study, 99 adult patients with tetralogy of Fallot, who had undergone a first pulmonary valve replacement late after initial total correction, were identified from the CONCOR (CONgenital CORvitia) registry. Computer-generated QRS durations were obtained from 12-lead electrocardio...
Abstract
Cited 5 times since 2006 (0.3 per year)
source: EuropePMC
International journal of cardiology,
Volume 114, Issue 1, 17 3 2006, Pages 1-3
Which patients should be referred for non-invasive angiography with multi-slice CT?
Bax JJ, Schuijf JD
Abstract
Cited 119 times since 2006 (6.3 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 48, Issue 9, 17 3 2006, Pages 1832-1838
Non-invasive visualization of the cardiac venous system in coronary artery disease patients using 64-slice computed tomography.
Van de Veire NR, Schuijf JD, De Sutter J, Devos D, Bleeker GB, de Roos A, van der Wall EE, Schalij MJ, Bax JJ
Objectives: This study was designed to evaluate the value of 64-slice computed tomography (CT) to visualize the cardiac veins and evaluate the relation between variations in venous anatomy and history of infarction. Background: Cardiac resynchronization therapy (CRT) is an attractive treatment for selected heart failure patients. Knowledge of venous anatomy may help in identifying candidates for successful left ventricular lead implantation. Methods: The 64-slice CT of 100 individuals (age 61 +/...
Abstract
Cited 4 times since 2006 (0.2 per year)
source: EuropePMC
The American journal of cardiology,
Volume 98, Issue 11, 16 3 2006, Pages 1515-1518
Impact of glomerular filtration rate on minor troponin T elevations for risk assessment in patients undergoing operation for abdominal aortic aneurysm or lower extremity arterial obstruction.
Feringa HH, Bax JJ, de Jonge R, Elhendy A, van Domburg RT, Dunkelgrun M, Schouten O, Karagiannis SE, Vidakovic R, Poldermans D
Debate surrounds the impact of renal function on the prognostic value of minor troponin T release in vascular surgery patients. The objective of this study was to assess the long-term prognostic value of minor degrees of troponin T release in patients who undergo major vascular surgery, especially those with concomitant renal dysfunction. Survivors of major noncardiac vascular surgery (n = 558) were preoperatively screened for cardiac risk factors and renal function. Serial troponin T was measur...
Abstract
Cited 12 times since 2006 (0.6 per year)
source: EuropePMC
Environmental pollution (Barking, Essex : 1987),
Volume 147, Issue 1, 12 2 2006, Pages 32-40
Distribution and movement of nutrients and metals in a Pinus radiata forest soil following applications of biosolids.
McLaren RG, Clucas LM, Speir TW, van Schaik AP
Samples of biosolids, spiked with increasing amounts of Cu, Ni or Zn were applied to field plots in a Pinus radiata forest, and the nutrient and metal status of the forest litter and underlying mineral soil was monitored over a period of six years following application. The macronutrient status of the forest litter was changed markedly by the biosolids application, with substantial increases in N, P and Ca concentrations, and decreases in Mg and K. The C/N ratio of the litter was also decreased...
Abstract
Cited 222 times since 2006 (11.8 per year)
source: EuropePMC
Gastroenterology,
Volume 132, Issue 1, 12 2 2006, Pages 66-75; quiz 432-3
Once-daily, high-concentration MMX mesalamine in active ulcerative colitis.
Kamm MA, Sandborn WJ, Gassull M, Schreiber S, Jackowski L, Butler T, Lyne A, Stephenson D, Palmen M, Joseph RE
Background & aims: SPD476 (LIALDA in the US; MEZAVANT in the EU; otherwise known as MMX mesalamine; Shire Pharmaceuticals Inc., Wayne, PA, under license from Giuliani SpA, Milan, Italy) is a novel, once-daily, high-strength (1.2 g/tablet) formulation of mesalamine, utilizing MMX Multi Matrix System (MMX) technology designed to deliver the active drug throughout the colon. We performed a double-blind, multicenter study, comparing MMX mesalamine vs placebo for the treatment of active ulcerativ...
Abstract
Cited 43 times since 2006 (2.3 per year)
source: EuropePMC
The British journal of ophthalmology,
Volume 91, Issue 3, 11 2 2006, Pages 313-318
Accuracy of GDx VCC, HRT I, and clinical assessment of stereoscopic optic nerve head photographs for diagnosing glaucoma.
Reus NJ, de Graaf M, Lemij HG
Aims: To determine and compare the accuracy and reproducibility of GDx variable cornea compensation (VCC) scanning laser polarimetry (SLP) with VCC, Heidelberg retina tomograph (HRT) I confocal scanning laser ophthalmoscopy (CSLO), and clinical assessment of stereoscopic optic nerve head (ONH) photographs for diagnosing glaucoma. Methods: One eye each of 40 healthy subjects, 48 glaucoma patients, and six patients with ocular hypertension were measured with SLP-VCC and CSLO. Simultaneous stereosc...
Abstract
Cited 11 times since 2006 (0.6 per year)
source: EuropePMC
Drug metabolism and disposition: the biological fate of chemicals,
Volume 35, Issue 1, 11 2 2006, Pages 67-71
A new CYP3A5 variant, CYP3A5*11, is shown to be defective in nifedipine metabolism in a recombinant cDNA expression system.
Lee SJ, van der Heiden IP, Goldstein JA, van Schaik RH
A new CYP3A5 variant, CYP3A5*11, was found in a white European subject by DNA sequencing. The CYP3A5*11 allele contains a single nucleotide polymorphism (SNP) (g.3775A>G) in exon 2, which results in a Tyr53Cys substitution, and a g.6986A>G splice change, the latter SNP previously reported in the defective CYP3A5*3 allele. However, the CYP3A5*3 is not a null allele because this variant is associated with leaky splicing, resulting in small amounts of functional protein still being produced....
Abstract
Cited 71 times since 2006 (3.8 per year)
source: EuropePMC
European heart journal,
Volume 28, Issue 15, 9 2 2006, Pages 1854-1861
Outcome of implantable cardioverter defibrillators in adults with congenital heart disease: a multi-centre study.
Yap SC, Roos-Hesselink JW, Hoendermis ES, Budts W, Vliegen HW, Mulder BJ, van Dijk AP, Schalij MJ, Drenthen W
Aims: To investigate outcome and complications of implantable cardioverter defibrillators (ICDs) in adults with congenital heart disease (CHD) and to identify predictors of (in-) appropriate shocks. Methods and results: Sixty-four CHD patients >/= 18 years at first ICD implantation [63% tetralogy of Fallot (TOF) and age at implantation 37 +/- 13 years] were identified using the Dutch adult CHD registry and a Belgian tertiary care centre database. Median follow-up duration was 3.7 years. Early...
Abstract
Cited 49 times since 2006 (2.6 per year)
source: EuropePMC
Clinical pharmacology and therapeutics,
Volume 80, Issue 4, 1 1 2006, Pages 367-374
MDR1 gene polymorphisms are associated with neuropsychiatric adverse effects of mefloquine.
Aarnoudse AL, van Schaik RH, Dieleman J, Molokhia M, van Riemsdijk MM, Ligthelm RJ, Overbosch D, van der Heiden IP, Stricker BH
Background: Mefloquine, a drug used for treatment and prophylaxis of malaria, is known for its neuropsychiatric adverse effects. We hypothesized that neuropsychiatric adverse effects of mefloquine are associated with polymorphisms in the MDR1/ABCB1 gene that encodes for the efflux pump P-glycoprotein. Methods: The association between MDR1 C1236T, G2677T, and C3435T single-nucleotide polymorphisms and the occurrence of neuropsychiatric adverse effects was examined in a prospective cohort study of...
Abstract
Circulation,
Volume 114, Issue 14, 1 1 2006, Pages e526; author reply e527
Letter by Schinkel et al regarding article, "Projected valve area at normal flow rate improves the assessment of stenosis severity in patients with low-flow, low-gradient aortic stenosis: the multicenter TOPAS (Truly or Pseudo-Severe Aortic Stenosis) study".
Schinkel AF, Bountioukos M, Poldermans D, Bax JJ
Abstract
Cited 45 times since 2006 (2.4 per year)
source: EuropePMC
The Journal of urology,
Volume 176, Issue 4 Pt 1, 1 1 2006, Pages 1349-53; discussion 1353
Phase II marker lesion study with intravesical instillation of apaziquone for superficial bladder cancer: toxicity and marker response.
van der Heijden AG, Moonen PM, Cornel EB, Vergunst H, de Reijke TM, van Boven E, Barten EJ, Puri R, van Kalken CK, Witjes JA
Purpose: We studied the ablative activity of intravesical apaziquone (EOquin) on a papillary marker tumor and determined the incidence of side effects. Materials and methods: A total of 46 patients with multiple pTa or pT1 bladder tumors underwent visible lesion resection except for 1 marker tumor. Patients were then treated with 6 instillations of apaziquone at weekly intervals. The response was determined 2 to 4 weeks after the last instillation. Results: One patient withdrew informed consent...
Abstract
Cited 57 times since 2006 (3 per year)
source: EuropePMC
Alimentary pharmacology & therapeutics,
Volume 24, Issue 7, 1 1 2006, Pages 1087-1097
Once daily MMX mesalazine for the treatment of mild-to-moderate ulcerative colitis: a phase II, dose-ranging study.
D'Haens G, Hommes D, Engels L, Baert F, van der Waaij L, Connor P, Ramage J, Dewit O, Palmen M, Stephenson D, Joseph R
Background: SPD476 (MMX mesalazine), is a novel, once daily, high-strength mesalazine formulation (1.2 g/tablet) that utilizes Multi Matrix System (MMX) technology to delay and extend delivery of the active drug throughout the colon. Aim: To assess the safety and efficacy of MMX mesalazine in patients with mild-to-moderately active ulcerative colitis, in a pilot, phase II, randomized, multicentre, double-blind, parallel-group, dose-ranging study (SPD476-202). Methods: Thirty-eight patients with...
Abstract
Cited 65 times since 2006 (3.4 per year)
source: EuropePMC
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
Volume 47, Issue 10, 1 1 2006, Pages 1565-1570
Extent of viability to predict response to cardiac resynchronization therapy in ischemic heart failure patients.
Ypenburg C, Schalij MJ, Bleeker GB, Steendijk P, Boersma E, Dibbets-Schneider P, Stokkel MP, van der Wall EE, Bax JJ
Unlabelled: The response to cardiac resynchronization therapy (CRT) varies significantly among individuals. Preliminary data suggest that the presence of myocardial viability may be important for response to CRT. The aim of this study was to evaluate whether the extent of viability could predict response to CRT after 6 mo. Methods: Sixty-one consecutive patients with advanced heart failure, left ventricular ejection fraction < 35%, QRS duration > 120 ms, and chronic coronary artery disease...
Abstract
Cited 39 times since 2006 (2.1 per year)
source: EuropePMC
American heart journal,
Volume 152, Issue 4, 1 1 2006, Pages 684.e11-6
Sustained effect of autologous bone marrow mononuclear cell injection in patients with refractory angina pectoris and chronic myocardial ischemia: twelve-month follow-up results.
Beeres SL, Bax JJ, Dibbets-Schneider P, Stokkel MP, Fibbe WE, van der Wall EE, Schalij MJ, Atsma DE
Background: Cell therapy has recently been introduced to treat patients with refractory angina. Because most studies have only included short-term follow-up, the effects of cell therapy over a longer period are unknown. Methods: In 25 patients (mean age 64 +/- 10 years, 21 men) with refractory angina, a total of 84 +/- 29 x 10(6) bone marrow-derived mononuclear cells was injected intramyocardially in regions with ischemia on technetium-99m tetrofosmin single-photon emission computed tomography....
Abstract
Cited 6 times since 2006 (0.3 per year)
source: EuropePMC
American heart journal,
Volume 152, Issue 4, 1 1 2006, Pages 636-640
Implantable defibrillator early after primary percutaneous intervention for ST-elevation myocardial infarction: rationale and design of the Defibrillator After Primary Angioplasty (DAPA) trial.
Ottervanger JP, Ramdat Misier AR, Zijlstra F, Schalij MJ, Wever E, Jordaens LJ, Henriques JP, de Boer MJ, Robbe HW, Wellens HJ, DAPA Investigators
Background: It has been shown that an implantable cardioverter defibrillator (ICD) may be beneficial when added to optimal drug treatment in patients with reduced left ventricular function who survive a myocardial infarction (MI). However, it is not known whether patients with increased risk of death after primary percutaneous coronary intervention (PCI) for ST-elevation MI also have benefit of prophylactic ICD therapy to reduce sudden cardiac death. Methods and study design: The DAPA trial is d...
Abstract
