9618 results
Cited 21 times since 2006 (1.1 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 17, Issue 10, 1 1 2006, Pages 1086-1092
Fragmented, long-duration, low-amplitude electrograms characterize the origin of focal atrial tachycardia.
De Groot NM, Schalij MJ
Background: Focal atrial tachycardias (FAT) originate from areas with poor cell-to-cell coupling. Due to cellular uncoupling extracellular potentials become fractionated. The degree of fragmentation may be used to identify the site of origin of FAT prior to catheter ablation. We studied electrical fragmentation in relation to the distance to the site of earliest activity during FAT. Methods: Three-dimensional (3-D) electroanatomical activation/voltage maps obtained from patients (n = 15: 6 male,...
Abstract
Cited 1 times since 2006 (0.1 per year)
source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation,
Volume 14, Issue 10, 1 1 2006, Pages 323-324
Genetic factors in arrhythmogenic right ventricular cardiomyopathy: need for a DNA bank!
van der Wall EE, Schalij MJ, van der Laarse A
Abstract
Cited 168 times since 2006 (8.9 per year)
source: EuropePMC
Journal of the American College of Cardiology,
Volume 48, Issue 8, 27 4 2006, Pages 1642-1648
Right ventricular pacing can induce ventricular dyssynchrony in patients with atrial fibrillation after atrioventricular node ablation.
Tops LF, Schalij MJ, Holman ER, van Erven L, van der Wall EE, Bax JJ
Objectives: This study was designed to assess the effects of long-term right ventricular (RV) pacing on left ventricular (LV) dyssynchrony, LV function, and heart failure symptoms. Background: Atrioventricular (AV) node ablation and subsequent long-term RV pacing is a well-established treatment option in patients with atrial fibrillation (AF). Methods: In 55 patients with drug-refractory AF, AV node ablation and implantation of a pacemaker was performed. At baseline and after a mean of 3.8 +/- 1...
Abstract
Cited 3 times since 2006 (0.2 per year)
source: EuropePMC
European heart journal,
Volume 27, Issue 20, 26 4 2006, Pages 2378-2379
Selecting optimal non-invasive cardiac imaging stress test in intermediate-risk patients using cost effectiveness analysis.
Poldermans D, Bax JJ
Abstract
Cited 25 times since 2006 (1.3 per year)
source: EuropePMC
Journal of cell science,
Volume 119, Issue Pt 20, 26 4 2006, Pages 4247-4256
Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells.
Raz V, Carlotti F, Vermolen BJ, van der Poel E, Sloos WC, Knaän-Shanzer S, de Vries AA, Hoeben RC, Young IT, Tanke HJ, Garini Y, Dirks RW
Apoptosis is fundamental to the regulation of homeostasis of stem cells in vivo. Whereas the pathways underlying the molecular and biochemical details of nuclear breakdown that accompanies apoptosis have been elucidated, the precise nature of nuclear reorganization that precedes the demolition phase is not fully understood. Here, we expressed an inducible caspase-8 in human mesenchymal stem cells, and quantitatively followed the early changes in nuclear organization during apoptosis. We found th...
Abstract
Cited 118 times since 2006 (6.2 per year)
source: EuropePMC
Stem cells (Dayton, Ohio),
Volume 25, Issue 2, 21 3 2006, Pages 271-278
Epicardial cells of human adults can undergo an epithelial-to-mesenchymal transition and obtain characteristics of smooth muscle cells in vitro.
van Tuyn J, Atsma DE, Winter EM, van der Velde-van Dijke I, Pijnappels DA, Bax NA, Knaän-Shanzer S, Gittenberger-de Groot AC, Poelmann RE, van der Laarse A, van der Wall EE, Schalij MJ, de Vries AA
Myocardial and coronary development are both critically dependent on epicardial cells. During cardiomorphogenesis, a subset of epicardial cells undergoes an epithelial-to-mesenchymal transition (EMT) and invades the myocardium to differentiate into various cell types, including coronary smooth muscle cells and perivascular and cardiac interstitial fibroblasts. Our current knowledge of epicardial EMT and the ensuing epicardium-derived cells (EPDCs) comes primarily from studies of chick and mouse...
Abstract
Journal of the American College of Cardiology,
Volume 48, Issue 7, 12 2 2006, Pages 1472; author reply 1472-3
Risk stratification with electrocardiographic-gated dobutamine stress imaging.
Elhendy A, Schinkel AF, Bax JJ, Poldermans D
Abstract
Cited 1 times since 2006 (0.1 per year)
source: EuropePMC
Bio Systems,
Volume 87, Issue 2-3, 10 2 2006, Pages 307-313
Directional hearing in a silicon cricket.
Reeve R, van Schaik A, Jin C, Hamilton T, Torben-Nielsen B, Webb B
Phonotaxis is the ability to orient towards or away from sound sources. Crickets can locate conspecifics by phonotaxis to the calling (mating) song they produce, and can evade bats by negative phonotaxis from echolocation calls. The behaviour and underlying physiology have been studied in some depth, and the auditory system solves this complex problem in a unique manner. Experiments conducted on a simulation model of the system indicated that the mechanism output a directional signal to sounds a...
Abstract
Cited 18 times since 2006 (0.9 per year)
source: EuropePMC
Heart rhythm,
Volume 4, Issue 1, 9 2 2006, Pages 88-91
Incessant ventricular tachycardia in fulminant lymphocytic myocarditis: Evidence for origin in the Purkinje system and successful treatment with ablation.
Zeppenfeld K, Blom NA, Bootsma M, Schalij MJ
Abstract
Cited 29 times since 2006 (1.5 per year)
source: EuropePMC
Molecular and cellular biology,
Volume 26, Issue 20, 5 1 2006, Pages 7731-7746
Identification of new human origins of DNA replication by an origin-trapping assay.
Gerhardt J, Jafar S, Spindler MP, Ott E, Schepers A
Metazoan genomes contain thousands of replication origins, but only a limited number have been characterized so far. We developed a two-step origin-trapping assay in which human chromatin fragments associated with origin recognition complex (ORC) in vivo were first enriched by chromatin immunoprecipitation. In a second step, these fragments were screened for transient replication competence in a plasmid-based assay utilizing the Epstein-Barr virus latent origin oriP. oriP contains two elements,...
Abstract
Cited 16 times since 2006 (0.8 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 13, Issue 5, 1 1 2006, Pages 635-641
Do risk factors influence the diagnostic accuracy of noninvasive coronary angiography with multislice computed tomography?
Schuijf JD, Mollet NR, Cademartiri F, Jukema JW, Lamb HJ, de Roos A, van der Wall EE, de Feyter PJ, Bax JJ
Background: Multislice computed tomography (MSCT) is a relatively new noninvasive imaging modality in the evaluation of patients with suspected coronary artery disease (CAD). Whether diagnostic accuracy is influenced by gender or risk factors for CAD is currently unknown and was evaluated in this study. Methods and results: In 197 patients (171 men and 26 women; mean age, 60 +/- 11 years) 16-slice MSCT was performed and compared with invasive coronary angiography at 2 different centers (Leiden a...
Abstract
Cited 36 times since 2006 (1.9 per year)
source: EuropePMC
World journal of gastroenterology,
Volume 12, Issue 35, 1 1 2006, Pages 5705-5710
Assessment of oxidative stress in chronic pancreatitis patients.
Verlaan M, Roelofs HM, van-Schaik A, Wanten GJ, Jansen JB, Peters WH, Drenth JP
Aim: To assess the levels of antioxidant capacity and oxidative damage in blood of chronic pancreatitis (CP) patients in comparison with those in healthy control subjects, by using several different analytical techniques. Methods: Thirty-five CP patients and 35 healthy control subjects were investigated prospectively with respect to plasma levels of thiols, ferric reducing ability of plasma (FRAP, i.e. antioxidant capacity), levels of protein carbonyls and thiobarbituric acid reactive substances...
Abstract
Cited 69 times since 2006 (3.6 per year)
source: EuropePMC
The oncologist,
Volume 11, Issue 8, 1 1 2006, Pages 944-954
Prophylaxis of irinotecan-induced diarrhea with neomycin and potential role for UGT1A1*28 genotype screening: a double-blind, randomized, placebo-controlled study.
de Jong FA, Kehrer DF, Mathijssen RH, Creemers GJ, de Bruijn P, van Schaik RH, Planting AS, van der Gaast A, Eskens FA, Janssen JT, Ruit JB, Verweij J, Sparreboom A, de Jonge MJ
Objective: Delayed-type diarrhea is a common side effect of irinotecan and is associated with a bacterial-mediated formation of the active irinotecan metabolite SN-38 from its glucuronide conjugate in the intestine. Based on a pilot study, we hypothesized that concomitant administration of the antibiotic neomycin would diminish exposure of the gut to SN-38 and ameliorate the incidence and severity of diarrhea. Patients and methods: Patients were treated with irinotecan in a multicenter, double-b...
Abstract
Cited 20 times since 2006 (1.1 per year)
source: EuropePMC
Preventive veterinary medicine,
Volume 77, Issue 3-4, 1 1 2006, Pages 186-198
Effect of Neospora caninum-serostatus on culling, reproductive performance and milk production in Dutch dairy herds with and without a history of Neospora caninum-associated abortion epidemics.
Bartels CJ, van Schaik G, Veldhuisen JP, van den Borne BH, Wouda W, Dijkstra T
We quantified the effect of Neospora caninum (NC)-serostatus on culling and (re)production in 83 herds randomly selected from the Dutch dairy herd population (random group) and in 17 herds that had experienced an abortion epidemic associated with NC infection (epidemic-abortion group). In the random group, a single whole-herd blood sampling was done during the spring of 2003, while in the epidemic-abortion group whole-herd blood sampling was done repeatedly at least once a year starting after th...
Abstract
Cited 44 times since 2006 (2.3 per year)
source: EuropePMC
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry,
Volume 14, Issue 9, 1 1 2006, Pages 777-786
Interpersonal psychotherapy for elderly patients in primary care.
van Schaik A, van Marwijk H, Adèr H, van Dyck R, de Haan M, Penninx B, van der Kooij K, van Hout H, Beekman A
Objective: Interpersonal psychotherapy (IPT) is recommended in most depression treatment guidelines, but little is known about its effectiveness in real-life practice. This study investigates whether IPT, delivered by mental health workers to elderly patients with major depressive disorder, is more effective than usual general practitioners' care (CAU). Methods: A pragmatic randomized, controlled trial was conducted in which 143 patients were allocated to IPT (10 sessions) or to CAU. PRIMar...
Abstract
Cited 60 times since 2006 (3.2 per year)
source: EuropePMC
The Journal of thoracic and cardiovascular surgery,
Volume 132, Issue 3, 1 1 2006, Pages 610-620
Surgical ventricular restoration in patients with ischemic dilated cardiomyopathy: evaluation of systolic and diastolic ventricular function, wall stress, dyssynchrony, and mechanical efficiency by pressure-volume loops.
Tulner SA, Steendijk P, Klautz RJ, Bax JJ, Schalij MJ, van der Wall EE, Dion RA
Objectives: Surgical ventricular restoration aims at improving cardiac function by normalization of left ventricular shape and size. Recent studies indicate that surgical ventricular restoration is highly effective with an excellent 5-year outcome in patients with ischemic dilated cardiomyopathy. We used pressure-volume analysis to investigate acute changes in systolic and diastolic left ventricular function, mechanical dyssynchrony and efficiency, and wall stress. Methods: In 3 patient groups (...
Abstract
Cited 7 times since 2006 (0.4 per year)
source: EuropePMC
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology,
Volume 13, Issue 5, 1 1 2006, Pages 629-634
Accuracy of stress Tc-99m tetrofosmin myocardial perfusion tomography for the diagnosis and localization of coronary artery disease in women.
Elhendy A, Schinkel AF, Bax JJ, van Domburg RT, Valkema R, Biagini E, Feringa HH, Poldermans D
Background: Earlier studies have suggested a modest accuracy of stress thallium 201 myocardial perfusion imaging (MPI) for the diagnosis of coronary artery disease (CAD) in women. The accuracy of stress MPI with technetium 99m tetrofosmin has not been studied in women. The aim of this study was to assess the accuracy of stress Tc-99m tetrofosmin MPI for the diagnosis and localization of CAD in women. Methods and results: We studied 88 women who underwent exercise or dobutamine stress Tc-99m tetr...
Abstract
Cited 16 times since 2006 (0.8 per year)
source: EuropePMC
Current opinion in cardiology,
Volume 21, Issue 5, 1 1 2006, Pages 443-449
Prognostic role of dobutamine stress echocardiography in myocardial viability.
Schinkel AF, Poldermans D, Elhendy A, Bax JJ
Purpose of review: The aim of this review is to provide a perspective on the role of dobutamine stress echocardiography to evaluate myocardial viability and assess prognosis in patients with ischemic left ventricular dysfunction. Recent findings: Pooled analysis of currently available data demonstrates that dobutamine stress echocardiography provides useful information on recovery of dysfunctional but viable myocardium and prognosis. In fact, improvement of long-term prognosis may be the ultimat...
Abstract
Cited 26 times since 2006 (1.4 per year)
source: EuropePMC
The Biochemical journal,
Volume 398, Issue 3, 1 1 2006, Pages 461-467
Involvement of the SMRT/NCoR-HDAC3 complex in transcriptional repression by the CNOT2 subunit of the human Ccr4-Not complex.
Jayne S, Zwartjes CG, van Schaik FM, Timmers HT
In eukaryotic cells, the Ccr4-Not complex can regulate mRNA metabolism at various levels. Previously, we showed that promoter targeting of the CNOT2 subunit resulted in strong repression of RNA polymerase II transcription, which was sensitive to the HDAC (histone deacetylase) inhibitor, trichostatin A [Zwartjes, Jayne, van den Berg and Timmers (2004) J. Biol. Chem. 279, 10848-10854]. In the present study, the cofactor requirement for CNOT2-mediated repression was investigated. We found that coex...
Abstract
Cited 2 times since 2006 (0.1 per year)
source: EuropePMC
Nederlands tijdschrift voor geneeskunde,
Volume 150, Issue 35, 1 1 2006, Pages 1930-1935
[Favourable results with surgical treatment in 43 children with hypoplastic left-heart syndrome or similar disorders, 1999-2005].
Hazekamp MG, Rijlaarsdam ME, Schoof PH, Wald AA, Blom NA, Ottenkamp J
Objective: To describe the results of surgical treatment of hypoplastic left-heart syndrome (HLHS) and HLHS-like disorders in the Amsterdam-Leiden Centre for Congenital Heart Disease, the Netherlands. Design: Retrospective, descriptive. Method: Data were collected on 43 neonates with HLHS or similar disorders who underwent surgical treatment between December 1999 and December 2005. HLHS was present in 37 patients and 6 had disorders similar to HLHS (unbalanced atrioventricular septal defect, tru...
Abstract
