Research

Publications

Below you can find a list of our published research.

6881 results

Cited 11 times since 2009 (0.7 per year) source: EuropePMC

The Journal of thoracic and cardiovascular surgery, Volume 138, Issue 5, 26 4 2009, Pages 1167-1171 Results of surgical repair of atrioventricular septal defect with double-orifice left atrioventricular valve. Hoohenkerk GJ, Wenink AC, Schoof PH, Koolbergen DR, Bruggemans EF, Rijlaarsdam M, Hazekamp MG

Objective: The outcome of surgical correction of atrioventricular septal defect with double-orifice left atrioventricular valve has improved in recent years but is still reported to be associated with high mortality and reoperation rates. Controversy exists about the management of the accessory orifice. We evaluated our results with correction of atrioventricular septal defect with double-orifice left atrioventricular valve. Methods: Between 1975 and 2006, 21 patients underwent correction of atr... Abstract

Cited 13 times since 2009 (0.8 per year) source: EuropePMC

Journal of cardiovascular electrophysiology, Volume 20, Issue 10, 26 4 2009, Pages 1119-1127 Patients with scar-related right ventricular tachycardia: determinants of long-term outcome. Wijnmaalen AP, Schalij MJ, Bootsma M, Kies P, DE Roos A, Putter H, Bax JJ, Zeppenfeld K

Introduction: Patients with established arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) based on task force (TF) criteria and ventricular tachycardia (VT) are at risk of VT recurrence and sudden death. Data on patients with VT due to right ventricular (RV) scar not fulfilling TF criteria are lacking. The purpose of this study was to assess the long-term arrhythmia recurrence rate and outcome in patients with scar-related right VT with and without a diagnosis of ARVC/D. Methods... Abstract

Cited 13 times since 2009 (0.8 per year) source: EuropePMC

Annals of biomedical engineering, Volume 37, Issue 9, 25 4 2009, Pages 1710-1726 Modeling the instantaneous pressure-volume relation of the left ventricle: a comparison of six models. Lankhaar JW, Rövekamp FA, Steendijk P, Faes TJ, Westerhof BE, Kind T, Vonk-Noordegraaf A, Westerhof N

Simulations are useful to study the heart's ability to generate flow and the interaction between contractility and loading conditions. The left ventricular pressure-volume (PV) relation has been shown to be nonlinear, but it is unknown whether a linear model is accurate enough for simulations. Six models were fitted to the PV-data measured in five sheep and the estimated parameters were used to simulate PV-loops. Simulated and measured PV-loops were compared with the Akaike information crit... Abstract

Cited 10 times since 2009 (0.6 per year) source: EuropePMC

The American journal of cardiology, Volume 104, Issue 5, 24 4 2009, Pages 653-656 Comparison of non-invasive multi-slice computed tomography coronary angiography versus invasive coronary angiography and fractional flow reserve for the evaluation of men with known coronary artery disease. van Werkhoven JM, Schuijf JD, Jukema JW, Pundziute G, de Roos A, Schalij MJ, van der Wall EE, Bax JJ

Multislice computed tomographic coronary angiography (MSCT) can accurately detect the presence of atherosclerosis noninvasively. However, a discrepancy has been observed between MSCT and noninvasive functional imaging. The purpose of the present study was to evaluate the correlation between MSCT and invasive fractional flow reserve (FFR) in men with known coronary artery disease. Thirty-three patients (mean age 57 +/- 11 years) clinically referred for coronary angiography underwent MSCT and FFR... Abstract

Cited 63 times since 2009 (4 per year) source: EuropePMC

PLoS medicine, Volume 6, Issue 6, 23 4 2009, Pages e1000099 Are markers of inflammation more strongly associated with risk for fatal than for nonfatal vascular events? Sattar N, Murray HM, Welsh P, Blauw GJ, Buckley BM, Cobbe S, de Craen AJ, Lowe GD, Jukema JW, Macfarlane PW, Murphy MB, Stott DJ, Westendorp RG, Shepherd J, Ford I, Packard CJ, Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) Study Group

Background: Circulating inflammatory markers may more strongly relate to risk of fatal versus nonfatal cardiovascular disease (CVD) events, but robust prospective evidence is lacking. We tested whether interleukin (IL)-6, C-reactive protein (CRP), and fibrinogen more strongly associate with fatal compared to nonfatal myocardial infarction (MI) and stroke. Methods and findings: In the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER), baseline inflammatory markers in up to 5,680 m... Abstract

Cited 196 times since 2009 (12.5 per year) source: EuropePMC

Circulation, Volume 120, Issue 1, 22 4 2009, Pages 28-34 Lipid treatment assessment project 2: a multinational survey to evaluate the proportion of patients achieving low-density lipoprotein cholesterol goals. Waters DD, Brotons C, Chiang CW, Ferrières J, Foody J, Jukema JW, Santos RD, Verdejo J, Messig M, McPherson R, Seung KB, Tarasenko L, Lipid Treatment Assessment Project 2 Investigators

Background: Information about physicians' adherence to cholesterol management guidelines remains scant. The present survey updates our knowledge of lipid management worldwide. Methods and results: Lipid levels were determined at enrollment in dyslipidemic adult patients on stable lipid-lowering therapy in 9 countries. The primary end point was the success rate, defined as the proportion of patients achieving appropriate low-density lipoprotein cholesterol (LDL-C) goals for their given risk.... Abstract

Cited 15 times since 2009 (1 per year) source: EuropePMC

The American journal of cardiology, Volume 104, Issue 4, 17 3 2009, Pages 480-485 Impact of time to reperfusion after acute myocardial infarction on myocardial damage assessed by left ventricular longitudinal strain. Bertini M, Mollema SA, Delgado V, Antoni ML, Ng AC, Holman ER, Boriani G, Schalij MJ, Bax JJ

The relation between cardiac troponin T (cTnT) and regional strain in patients with acute myocardial infarction (AMI) was investigated. Furthermore, the effect of symptoms-to-balloon time on impairment in regional strain after AMI was evaluated. A total of 157 consecutive patients with AMI who underwent primary percutaneous coronary intervention were included. Two-dimensional echocardiography soon after percutaneous coronary intervention was performed. Speckle-tracking analysis was applied to as... Abstract

Cited 5 times since 2009 (0.3 per year) source: EuropePMC

European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology, Volume 10, Issue 5, 13 2 2009, Pages 602-606 Screening for abdominal aortic aneurysms using a dedicated portable ultrasound system: early results. Flu WJ, van Kuijk JP, Merks EJ, Kuiper R, Verhagen HJ, Bosch JG, Bom N, Bax JJ, Poldermans D

Aims: Abdominal aortic aneurysms (AAA) are often diagnosed at time of (impending) rupture leading to a dramatic increase of morbidity and mortality. A simple screening device might be the key solution for widespread AAA screening. This study evaluated the diagnostic accuracy of a new portable ultrasound scanner (Aortascan BVI 9600) developed for automatic AAA detection. Methods and results: A total of 150 patients with presumed aneurysmatic peripheral atherosclerotic disease were included in the... Abstract

Cited 23 times since 2009 (1.5 per year) source: EuropePMC

Pituitary, Volume 12, Issue 4, 12 2 2009, Pages 339-346 Limited effects of growth hormone replacement in patients with GH deficiency during long-term cure of acromegaly. van der Klaauw AA, Bax JJ, Roelfsema F, Stokkel MP, Bleeker GB, Biermasz NR, Smit JW, Romijn JA, Pereira AM

The aim of this study was to assess the effects of replacement with recombinant human growth hormone (rhGH) in patients with GH deficiency (GHD) after treatment of acromegaly. Intervention study. Sixteen patients (8 men, age 56 years), treated for acromegaly by surgery and radiotherapy, with an insufficient GH response to insulin-induced hypoglycaemia, were treated with 1 year of rhGH replacement. Study parameters were assessed at baseline and after 1 year of rhGH replacement. Study parameters w... Abstract

Cited 72 times since 2009 (4.6 per year) source: EuropePMC

The American journal of cardiology, Volume 104, Issue 3, 6 1 2009, Pages 312-317 Validation of echocardiographic two-dimensional speckle tracking longitudinal strain imaging for viability assessment in patients with chronic ischemic left ventricular dysfunction and comparison with contrast-enhanced magnetic resonance imaging. Roes SD, Mollema SA, Lamb HJ, van der Wall EE, de Roos A, Bax JJ

The purpose of the present study was to compare longitudinal strain assessed by two-dimensional speckle tracking with scar tissue on contrast-enhanced magnetic resonance imaging (MRI) in patients with chronic ischemic left ventricular (LV) dysfunction. The aim was also to define a cutoff value for regional strain to discriminate between viable myocardium and transmural scar. Ninety patients with chronic ischemic LV dysfunction underwent transthoracic echocardiography to measure global and segmen... Abstract

Cited 3 times since 2009 (0.2 per year) source: EuropePMC

The American journal of cardiology, Volume 104, Issue 3, 6 1 2009, Pages 440-446 Usefulness of multimodality imaging for detecting differences in temporal occurrence of left ventricular systolic mechanical events in healthy young adults. Marsan NA, Tops LF, Westenberg JJ, Delgado V, de Roos A, van der Wall EE, Schalij MJ, Bax JJ

Detailed information about the absolute temporal occurrence of myocardial motion and deformation events during the cardiac cycle is still lacking. However, the normal time range of these parameters may be of great importance as a reference for detecting and interpreting mechanical dyssynchrony and for identifying a delayed contraction in case of left ventricular (LV) dysfunction. The aim of this study was to determine in young healthy subjects and for different LV segments the value of (1) time... Abstract

Cited 4 times since 2009 (0.3 per year) source: EuropePMC

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, Volume 11, Issue 8, 3 1 2009, Pages 1002-1003 Validation of success following atrial fibrillation ablation: a European survey. Halimi F, Van Erven L, EHRA Scientific Initiatives Committee

This survey sampled the follow-up (FU) strategies for atrial fibrillation ablation used by electrophysiology/ablation centres in Europe. Currently, FU relies on symptoms and short-term ECG recordings rather than monitoring by implantable devices. The responding centres show a lack of confidence in the long-term success after ablation, and confusion about definition of success which needs to be informed by updated European guidelines. Abstract

Cited 17 times since 2009 (1.1 per year) source: EuropePMC

Circulation. Arrhythmia and electrophysiology, Volume 2, Issue 3, 3 1 2009, Pages 242-248 Long-term outcome of ablative therapy of postoperative supraventricular tachycardias in patients with univentricular heart: a European multicenter study. de Groot NM, Lukac P, Blom NA, van Kuijk JP, Pedersen AK, Hansen PS, Delacretaz E, Schalij MJ

Background: Catheter ablation has evolved as a possible curative treatment modality for supraventricular tachycardias (SVT) in patients with univentricular heart. However, the long-term outcome of ablation procedures is unknown. We evaluated the procedural and long-term outcome of ablative therapy of late postoperative SVT in patients with univentricular heart. Methods and results: Patients with univentricular heart (n=19, 11 male; age, 29+/-9 years) referred for ablation of SVT were studied. Ab... Abstract

Cited 29 times since 2009 (1.8 per year) source: EuropePMC

European heart journal, Volume 30, Issue 13, 2 1 2009, Pages 1621-1626 Recurrence of ventricular arrhythmias in ischaemic secondary prevention implantable cardioverter defibrillator recipients: long-term follow-up of the Leiden out-of-hospital cardiac arrest study (LOHCAT). Borleffs CJ, van Erven L, Schotman M, Boersma E, Kiès P, van der Burg AE, Zeppenfeld K, Bootsma M, van der Wall EE, Bax JJ, Schalij MJ

Aims: To assess the long-term rate of mortality and the recurrence of potentially life-threatening ventricular arrhythmias in secondary prevention implantable cardioverter defibrillator (ICD) patients and to construct a model for baseline risk stratification. Methods and results: Since 1996, all patients with ischaemic heart disease, receiving ICD therapy for secondary prevention of sudden death, were included in the current study. Patients were evaluated at implantation and during long-term fol... Abstract

Cited 18 times since 2009 (1.1 per year) source: EuropePMC

Comparative medicine, Volume 59, Issue 3, 1 1 2009, Pages 280-286 Comparison of 3 methods to induce acute pulmonary hypertension in pigs. Roehl AB, Steendijk P, Baumert JH, Schnoor J, Rossaint R, Hein M

Large animal models for acute pulmonary hypertension (PHT) show distinct differences between species and underlying mechanisms. Two embolic procedures and continuous infusion of a stable thromboxane A(2) analogue (U46619) were explored for their ability to induce PHT and their effects on right ventricular function and pulmonary and systemic circulation in 9 pigs. Injection of small (100 to 200 microm) or large (355 to 425 microm) polystyrene beads and incremental dosage (0.2 to 0.8 microg kg(-1)... Abstract

Cited 5 times since 2009 (0.3 per year) source: EuropePMC

Coronary artery disease, Volume 20, Issue 4, 1 1 2009, Pages 281-287 Head-to-head comparison between bicycle exercise testing and coronary calcium score and coronary stenoses on multislice computed tomography. Pundziute G, Schuijf JD, van Werkhoven JM, Nucifora G, van der Wall EE, Wouter Jukema J, Bax JJ

Objective: To perform a head-to-head comparison between signs of ischemia during bicycle exercise testing and coronary atherosclerosis on multislice computed tomography (MSCT) in patients with suspected coronary artery disease (CAD). Methods: Two hundred and one patients underwent exercise testing, followed by 64-slice MSCT. A subgroup of 63 (31%) patients also underwent conventional coronary angiography. The exercise test was positive or negative based on electrocardiographic signs of ischemia.... Abstract

Cited 145 times since 2009 (9.2 per year) source: EuropePMC

Annals of surgery, Volume 249, Issue 6, 1 1 2009, Pages 921-926 Bisoprolol and fluvastatin for the reduction of perioperative cardiac mortality and myocardial infarction in intermediate-risk patients undergoing noncardiovascular surgery: a randomized controlled trial (DECREASE-IV). Dunkelgrun M, Boersma E, Schouten O, Koopman-van Gemert AW, van Poorten F, Bax JJ, Thomson IR, Poldermans D, Dutch Echocardiographic Cardiac Risk Evaluation Applying Stress Echocardiography Study Group

Objective: This study evaluated the effectiveness and safety of beta-blockers and statins for the prevention of perioperative cardiovascular events in intermediate-risk patients undergoing noncardiovascular surgery. Summary background data: Beta-blockers and statins reduce perioperative cardiac events in high-risk patients undergoing vascular surgery by restoring the myocardial oxygen supply/demand balance and/or stabilizing coronary plaques. However, their effects in intermediate-risk patients... Abstract

Current problems in cardiology, Volume 34, Issue 6, 1 1 2009, Pages 277-295 Classic images: Cardiac computed tomography. Schuijf JD, Kroft LJ, de Roos A, Bax JJ

Cardiac computed tomography (CT) has evolved into a valuable clinical tool for cardiac evaluation. Cardiac CT is increasingly used for imaging of the coronary arteries for the evaluation of (suspected) coronary artery disease, but many other cardiac structures may be the topic for CT investigation. This article reviews general indications for cardiac CT imaging. Common variants and pathologies of the cardiovascular system are illustrated by clinical examples. Abstract

Cited 16 times since 2009 (1 per year) source: EuropePMC

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 22, Issue 6, 1 1 2009, Pages 688-694 Changes in global left ventricular function by multidirectional strain assessment in heart failure patients undergoing cardiac resynchronization therapy. Delgado V, Ypenburg C, Zhang Q, Mollema SA, Fung JW, Schalij MJ, Yu CM, Bax JJ

Background: The aim of this study was to evaluate the acute and late effects of cardiac resynchronization therapy (CRT) on multidirectional left ventricular (LV) strain assessed by two-dimensional speckle-tracking imaging and automated function imaging (AFI). Methods: Multidirectional LV strain (global radial strain [GRS Avg], global circumferential strain [GCS Avg], and global longitudinal peak systolic strain [GLPSS Avg]) were measured in 141 patients with heart failure before CRT implantation... Abstract

Cited 1 times since 2009 (0.1 per year) source: EuropePMC

Journal of paediatrics and child health, Volume 45, Issue 6, 1 1 2009, Pages 391-392 Arachnoid cyst and costovertebral defects in Aicardi syndrome. Yüksel D, Yilmaz D, Usak E, Senbil N, Gürer Y

Abstract