Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
8892 results
Cited 1 times since 2024 (0.8 per year) source: EuropePMC
Annals of vascular surgery, Volume 108, 25 4 2024, Pages 385-392 Prognostic Performance of the Maximal Systolic Acceleration at the Hallux in Healing of Foot Ulcers: A Retrospective Cohort Study. Willems SA, Pruim JD, van der Vorst JR, van Schaik J, Schepers A, Hamming JF, Brouwers JJWM
Background: The accurate prediction of foot ulcer healing remains a major challenge in clinical practice. To date, no reliable bedside tests are available. The primary aim of this study was to determine the prognostic performance of the maximal systolic acceleration (ACCmax) to predict ulcer healing. Secondary objectives comprised the investigation of the prognostic accuracy in patients prone to medial arterial calcification and to assess the potential risk of amputation. Methods: A single-cente... Abstract
Cited 21 times since 2024 (17 per year) source: EuropePMC
Alzheimer's & dementia : the journal of the Alzheimer's Association, Volume 20, Issue 9, 24 4 2024, Pages 5973-5995 A genome-wide association meta-analysis of all-cause and vascular dementia. Mega Vascular Cognitive Impairment and Dementia (MEGAVCID) consortium
Introduction: Dementia is a multifactorial disease with Alzheimer's disease (AD) and vascular dementia (VaD) pathologies making the largest contributions. Yet, most genome-wide association studies (GWAS) focus on AD. Methods: We conducted a GWAS of all-cause dementia (ACD) and examined the genetic overlap with VaD. Our dataset includes 800,597 individuals, with 46,902 and 8702 cases of ACD and VaD, respectively. Known AD loci for ACD and VaD were replicated. Bioinformatic analyses prioritiz... Abstract
Frontiers in bioengineering and biotechnology, Volume 12, 22 4 2024, Pages 1435695 Biofilm mitigation in hybrid chemical-biological upcycling of waste polymers. Stoddard H, Kulas D, Zolghadr A, Aloba S, Schaerer LG, Putman L, Valencia I, Lacey JA, Shonnard DR, Techtmann SM, Ong RG
Introduction: Accumulation of plastic waste in the environment is a serious global issue. To deal with this, there is a need for improved and more efficient methods for plastic waste recycling. One approach is to depolymerize plastic using pyrolysis or chemical deconstruction followed by microbial-upcycling of the monomers into more valuable products. Microbial consortia may be able to increase stability in response to process perturbations and adapt to diverse carbon sources, but may be more li... Abstract
Cited 5 times since 2024 (4 per year) source: EuropePMC
Journal of cardiovascular medicine (Hagerstown, Md.), Volume 25, Issue 9, 22 4 2024, Pages 715-716 Invasive evaluation of coronary artery compliance modification after intracoronary lithotripsy. Oliveri F, Van Oort M, Al Amri I, Bingen B, Van der Kley F, Jukema W, Montero J
Cardiovascular revascularization medicine : including molecular interventions, Volume 70, 22 4 2024, Pages 85-91 Intravascular lithotripsy for the treatment of peri-stent calcific lesions in saphenous vein grafts: A case series report. Meijer M, Oliveri F, van Oort MJH, Bingen BO, van der Kley F, Jukema JW, Al Amri I, Montero-Cabezas JM
Background: Coronary artery bypass grafting (CABG) is a cornerstone treatment for coronary artery disease, with the use of saphenous vein grafts (SVGs) being prevalent. However, SVGs are susceptible to high failure rates due to graft inflammation, intimal hyperplasia, and atherosclerosis, leading to a substantial number of patients requiring revascularization. Percutaneous coronary intervention (PCI) of SVGs poses unique challenges, including increased risk of distal embolization and perforation... Abstract
Cited 1 times since 2024 (0.8 per year) source: EuropePMC
International journal of cardiology, Volume 413, 22 4 2024, Pages 132387 Mitral valve repair with resection and non-resection techniques in Barlow's disease: A multi-center study. Tomšič A, Holubec T, Sandoval E, Pham T, Castella M, Klautz RJM, Marsan NA, Pereda D, Palmen M
Background: Various mitral valve (MV) repair techniques are nowadays in use. Non-resection techniques, that rely exclusively on Gore-Tex® neochords and annuloplasty, have been popularized; however, their efficacy in Barlow's disease, characterized by large myxomatous leaflets, is yet unclear. Methods: Consecutive patients undergoing MV repair for Barlow's disease between 2011 and 2019 were selected on the basis of being eligible for resection and non-resection techniques. Study endpoin... Abstract
Cited 1 times since 2024 (0.8 per year) source: EuropePMC
Rheumatology (Oxford, England), 22 4 2024, Pages keae375 Preventive effects of early immunosuppressive treatment on the development of interstitial lung disease in systemic sclerosis. Velauthapillai A, Bootsma MFR, Bruni C, Bergmann C, Matucci-Cerinic M, Launay D, Riemekastan G, Garzanova L, Airò P, Rezus E, da Silva JAP, Del Galdo F, Hunzelmann N, Chung LS, Krasowska D, Distler O, van den Ende CHM, Vonk MC, EUSTAR collaborators
Background: Hypothesizing that early treatment yields improved prognosis, we aimed to investigate how the timing of immunosuppressive treatment relates to interstitial lung disease (ILD) development and the course of pulmonary function in systemic sclerosis (SSc). Methods: A cohort was created using data from the EUSTAR database and Nijmegen Systemic Sclerosis cohort, including adult patients who started their first immunosuppressive treatment (ie mycophenolate mofetil, methotrexate, cyclophosph... Abstract
Cited 2 times since 2024 (1.6 per year) source: EuropePMC
The Science of the total environment, Volume 948, 20 3 2024, Pages 174907 Accumulation of airborne microplastics on leaves of different tree species in the urban environment. Leitão IA, Van Schaik L, Iwasaki S, Ferreira AJD, Geissen V
Microplastics (MPs) are omnipresent in the environment and they are linked to ecosystem and human health problems. The atmospheric transport of MPs and the role of tree leaves in MP atmospheric deposition has not been adequately studied. MP concentrations on the leaves of different tree species in urban regions of the Netherlands and Portugal, along with related MP deposition, were investigated in this study. We collected leaves from cedar, eucalyptus, oak, pine and willow trees, together with m... Abstract
Cited 1 times since 2024 (0.8 per year) source: EuropePMC
Clinical chemistry and laboratory medicine, Volume 62, Issue 12, 19 3 2024, Pages e255-e256 Is uracil enough for effective pre-emptive DPD testing? Heersche N, Matic M, Mathijssen RHJ, Coenen MJH, van Schaik RHN
Cited 11 times since 2024 (8.8 per year) source: EuropePMC
Preventive veterinary medicine, Volume 231, 19 3 2024, Pages 106289 The impact of the bluetongue serotype 3 outbreak on sheep and goat mortality in the Netherlands in 2023. Santman-Berends IMGA, van den Brink KMJA, Dijkstra E, van Schaik G, Spierenburg MAH, van den Brom R
In September 2023, bluetongue virus serotype 3 (BTV-3) emerged in the Netherlands, infecting over five thousand livestock farms. In sheep, high morbidity and mortality rates were reported that were unlike previously described bluetongue outbreaks. This study aimed to quantify the impact of BTV-3 in the small ruminant population in the Netherlands in 2023. Sheep and goat movement census data and BTV-3 notification data were available from 2020 until the end of 2023. Data were aggregated to farm a... Abstract
Journal of visualized experiments : JoVE, Issue 209, 19 3 2024 Imaging and Quantification of the Hepatic Vasculature of Mice Using Ultrafast Doppler Ultrasound. Stripling K, Timmermans F, Décombas-Deschamps S, Thalgott JH, Lemonnier D, de Vries MR, Rabelink TJ, Tanter M, Deffieux T, Lebrin F
Non-invasive in vivo imaging of the vasculature is a powerful tool for studying disease mechanisms in rodents. To achieve high sensitivity imaging of the microvasculature using Doppler ultrasound methods, imaging modalities employing the concept of ultrafast imaging are preferred. By increasing the frame rate of the ultrasound scanner to thousands of frames per second, it becomes possible to improve the sensitivity of the blood flow down to 2 mm/s and to obtain functional information about the m... Abstract
Cited 3 times since 2024 (2.4 per year) source: EuropePMC
United European gastroenterology journal, Volume 12, Issue 10, 19 3 2024, Pages 1367-1377 T1 colorectal cancer patients' perspective on information provision and therapeutic decision-making after local resection. Dekkers N, Dang H, de Graaf M, Nobbenhuis K, Verhoeven DA, van der Kraan J, de Vos Tot Nederveen Cappel WH, Alkhalaf A, van Westreenen HL, Basiliya K, Peeters KCMJ, Westerterp M, Doornebosch PG, Hardwick JCH, Langers AMJ, Boonstra JJ
Background: Decision-making after local resection of T1 colorectal cancer (T1CRC) is often complex and calls for optimal information provision as well as active patient involvement. Objective: The aim was to evaluate the perceptions of patients with T1CRC on information provision and therapeutic decision-making. Methods: This multicenter cross-sectional study included patients who underwent endoscopic or local surgical resection as initial treatment. Information provision was assessed using the... Abstract
Cited 26 times since 2024 (20.8 per year) source: EuropePMC
The Journal of molecular diagnostics : JMD, Volume 26, Issue 10, 18 3 2024, Pages 851-863 DPYD Genotyping Recommendations: A Joint Consensus Recommendation of the Association for Molecular Pathology, American College of Medical Genetics and Genomics, Clinical Pharmacogenetics Implementation Consortium, College of American Pathologists, Dutch Pharmacogenetics Working Group of the Royal Dutch Pharmacists Association, European Society for Pharmacogenomics and Personalized Therapy, Pharmacogenomics Knowledgebase, and Pharmacogene Variation Consortium. Pratt VM, Cavallari LH, Fulmer ML, Gaedigk A, Hachad H, Ji Y, Kalman LV, Ly RC, Moyer AM, Scott SA, Turner AJ, van Schaik RHN, Whirl-Carrillo M, Weck KE
The goals of the Association for Molecular Pathology Clinical Practice Committee's Pharmacogenomics (PGx) Working Group are to define the key attributes of pharmacogenetic alleles recommended for clinical testing and a minimum set of variants that should be included in clinical PGx genotyping assays. This document series provides recommendations for a minimum set of variant alleles (tier 1) and an extended list of variant alleles (tier 2) that will aid clinical laboratories when designing a... Abstract
Cited 1 times since 2024 (0.8 per year) source: EuropePMC
Heart rhythm O2, Volume 5, Issue 9, 17 3 2024, Pages 614-622 Remarkably high and accelerating failure rate of a widely used implantable cardioverter-defibrillator lead: A large-scale manufacturer-independent multicenter study with long accurate follow-up. Oosterwerff EFJ, Theuns DAMJ, Maass AH, van Erven L
Background: A high annual failure rate of the Linox family defibrillator lead was reported in various small single-center studies. No independent multicenter long-term performance information exists for this lead. Objective: Our aim was to assess the longevity of the Linox family leads and to evaluate clinical variables and adverse events associated with failure. Methods: This 4-center study included adults >18 years of age who received Linox family leads for the prevention of sudden cardiac... Abstract
Cited 1 times since 2024 (0.8 per year) source: EuropePMC
Journal of vascular surgery, Volume 80, Issue 5, 17 3 2024, Pages 1418-1424.e1 Urgent Candy-Plug technique for distal false lumen occlusion in chronic aortic dissection. Eleshra A, Kölbel T, Haulon S, Bertoglio L, Rohlffs F, Dias N, Panuccio G, Tsilimparis N, Candy-Plug Collaborators
Objective: This study aimed to assess the impact of urgency on early and midterm outcomes of the Candy-Plug (CP) technique for distal false lumen (FL) occlusion in thoracic endovascular aortic repair for aortic dissection. Methods: The CP registry was reviewed, and patients were categorized into elective and urgent/emergent groups for analysis. End points included technical success, clinical success, early (30-day) computed tomography angiography findings, early (30-day) mortality, adverse event... Abstract
Cited 11 times since 2024 (8.8 per year) source: EuropePMC
Nature genetics, Volume 56, Issue 8, 17 3 2024, Pages 1689-1700 Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer. Zhao SG, Bootsma M, Zhou S, Shrestha R, Moreno-Rodriguez T, Lundberg A, Pan C, Arlidge C, Hawley JR, Foye A, Weinstein AS, Sjöström M, Zhang M, Li H, Chesner LN, Rydzewski NR, Helzer KT, Shi Y, West Coast Dream Team Consortium, Lynch M, Dehm SM, Lang JM, Alumkal JJ, He HH, Wyatt AW, Aggarwal R, Zwart W, Small EJ, Quigley DA, Lupien M, Feng FY
The impact of variations in the three-dimensional structure of the genome has been recognized, but solid cancer tissue studies are limited. Here, we performed integrated deep Hi-C sequencing with matched whole-genome sequencing, whole-genome bisulfite sequencing, 5-hydroxymethylcytosine (5hmC) sequencing and RNA sequencing across a cohort of 80 biopsy samples from patients with metastatic castration-resistant prostate cancer. Dramatic differences were present in gene expression, 5-methylcytosine... Abstract
Cited 12 times since 2024 (9.6 per year) source: EuropePMC
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 37, Issue 11, 17 3 2024, Pages 1083-1102 Advances in the Assessment of Patients With Tricuspid Regurgitation: A State-of-the-Art Review on the Echocardiographic Evaluation Before and After Tricuspid Valve Interventions. Badano LP, Tomaselli M, Muraru D, Galloo X, Li CHP, Ajmone Marsan N
Tricuspid regurgitation (TR) can have a significant impact on the health and mortality of a patient. Unfortunately, many patients with advanced right-sided heart failure are not referred for isolated tricuspid valve (TV) surgery in a timely manner. This delayed referral has resulted in a high in-hospital mortality rate and significant undertreatment. Fortunately, transcatheter TV intervention (TTVI) has emerged as a safe and effective alternative to surgery, successfully reducing TR severity and... Abstract
Cited 7 times since 2024 (5.6 per year) source: EuropePMC
Circulation. Cardiovascular imaging, Volume 17, Issue 7, 16 3 2024, Pages e016481 Rapid Plaque Progression Is Independently Associated With Hyperglycemia and Low HDL Cholesterol in Patients With Stable Coronary Artery Disease: A PARADIGM Study. Neglia D, Caselli C, Maffei E, Cademartiri F, Meloni A, Bossone E, Saba L, Lee SE, Sung JM, Andreini D, Al-Mallah MH, Budoff MJ, Chinnaiyan K, Choi JH, Chun EJ, Conte E, Gottlieb I, Hadamitzky M, Kim YJ, Lee BK, Leipsic JA, Marques H, de Araújo Gonçalves P, Pontone G, Shin S, Stone PH, Samady H, Virmani R, Narula J, Shaw LJ, Bax JJ, Lin FY, Min JK, Chang HJ
Background: We assessed whether combinations of cardiometabolic risk factors independently predict coronary plaque progression (PP) and major adverse cardiovascular events in patients with stable coronary artery disease. Methods: Patients with known or suspected stable coronary artery disease (60.9±9.3 years, 55.4% male) undergoing serial coronary computed tomography angiographies (≥2 years apart), with clinical characterization and follow-up (N=1200), were analyzed from the PARADIGM study (Prog... Abstract
Journal of clinical epidemiology, Volume 173, 15 3 2024, Pages 111464 Estimating uncertainty when providing individual cardiovascular risk predictions: a Bayesian survival analysis. Hageman SHJ, Post RAJ, Visseren FLJ, McEvoy JW, Jukema JW, Smulders Y, van Smeden M, Dorresteijn JAN, UCC-SMART Study Group
Background: Cardiovascular disease (CVD) risk scores provide point estimates of individual risk without uncertainty quantification. The objective of the current study was to demonstrate the feasibility and clinical utility of calculating uncertainty surrounding individual CVD-risk predictions using Bayesian methods. Study design and setting: Individuals with established atherosclerotic CVD were included from the Utrecht Cardiovascular Cohort-Secondary Manifestations of ARTerial disease (UCC-SMAR... Abstract
Cited 2 times since 2024 (1.6 per year) source: EuropePMC
Critical reviews in oncology/hematology, Volume 202, 14 2 2024, Pages 104441 Factors for a broad technology assessment of comprehensive genomic profiling in advanced cancer, a systematic review. van Schaik LF, Engelhardt EG, Wilthagen EA, Steeghs N, Fernández Coves A, Joore MA, van Harten WH, Retèl VP
Comprehensive Genomic Profiling (CGP) allows for the identification of many targets. Reimbursement decision-making is, however, challenging because besides the health benefits of on-label treatments and costs, other factors related to diagnostic and treatment pathways may also play a role. The aim of this study was to identify which other factors are relevant for the technology assessment of CGP and to summarize the available evidence for these factors. After a scoping search and two expert sess... Abstract