Research

Publications

Below you can find a list of our published research.

9516 results

Cited 11 times since 2008 (0.6 per year) source: EuropePMC

The journal of mental health policy and economics, Volume 11, Issue 1, 1 1 2008, Pages 3-15 Are psychological treatments for depression in primary care cost-effective? Bosmans JE, van Schaik DJ, de Bruijne MC, van Hout HP, van Marwijk HW, van Tulder MW, Stalman WA

Background: Depression is a highly prevalent condition that is associated with high levels of work absenteeism and high health care costs. Most patients are treated in primary care. A large group of patients prefers psychological treatments to antidepressants. Aims of the study: To systematically review the evidence for the cost-effectiveness of psychological treatments, psychotherapy and counselling, in comparison with usual care or antidepressant treatment in adult primary care patients with d... Abstract

Cited 3 times since 2008 (0.2 per year) source: EuropePMC

Vascular, Volume 16, Issue 2, 1 1 2008, Pages 116-119 Inflammatory aneurysm of the common iliac artery mimicking appendicitis. Mieog JS, Stoot JH, Bosch JJ, Koning OH, Hamming JF

Isolated inflammatory aneurysm of the common iliac artery is a rare condition. Previously reported cases presented with urologic complications owing to entrapment of the ureter in the perianeurysmal fibrosis. We report a case of a healthy young man who presented with acute abdominal pain in the right lower quadrant without urologic complications mimicking acute appendicitis. The pain was caused by an isolated inflammatory aneurysm of the right common iliac artery measuring 4 cm in diameter. Thre... Abstract

Annals of surgery, Volume 247, Issue 3, 1 1 2008, Pages 555; author reply 555-6 Re: Laparoscopic Versus Open Appendectomy in Children: A Meta-analysis. Aziz MI, van der Burg BL, Hamming JF

Abstract

Cited 31 times since 2008 (1.8 per year) source: EuropePMC

World journal of gastroenterology, Volume 14, Issue 10, 1 1 2008, Pages 1633-1635 Melanoma of the rectum: a rare entity. van Schaik PM, Ernst MF, Meijer HA, Bosscha K

A 41-year-old man presented with a 6-mo history of changed defecation and rectal bleeding. A 3-cm polypoid tumor of the lower rectum was found at rectosigmoidoscopy, which proved to be a leiomyosarcoma upon biopsy. Dissemination studies did not show any metastases. He was underwent to an abdomino-perineal resection (APR). Histopathology of the specimen showed a melanoma (S-100 stain positive). Two years after the resection, metastases in the abdomen and right lung were found. He died one and hal... Abstract

Cited 51 times since 2008 (2.9 per year) source: EuropePMC

American journal of hematology, Volume 83, Issue 3, 1 1 2008, Pages 200-202 UGT2B7 promoter variant -840G>A contributes to the variability in hepatic clearance of morphine in patients with sickle cell disease. Darbari DS, van Schaik RH, Capparelli EV, Rana S, McCarter R, van den Anker J

The purpose of the study was to determine if UDP-glucuronosyltransferase (UGT) 2B7 allelic variants encoding for UGT2B7, primary enzyme responsible for morphine glucuronidation contribute to the variability in the hepatic clearance of morphine in sickle cell disease (SCD). Twenty-four hour PK study of morphine and UGT2B7 variants genotyping was performed in 20 SCD patients in a steady state of health. Presence of the -840G allele (GG and GA) was associated with lower morphine metabolites/morphin... Abstract

Cited 10 times since 2008 (0.6 per year) source: EuropePMC

JACC. Cardiovascular imaging, Volume 1, Issue 2, 1 1 2008, Pages 190-199 Invasive versus noninvasive evaluation of coronary artery disease. Schuijf JD, van Werkhoven JM, Pundziute G, Jukema JW, Decramer I, Stokkel MP, Dibbets-Schneider P, Schalij MJ, Reiber JH, van der Wall EE, Wijns W, Bax JJ

Objectives: We sought to compare the diagnostic information obtained from noninvasive characterization of coronary artery disease by using multidetector computed tomography (MDCT) and myocardial perfusion imaging (MPI) and to compare findings with the use of invasive coronary angiography and intravascular ultrasound (IVUS). Background: Preliminary comparisons have suggested that abnormal myocardial perfusion studies correlate well with significant luminal stenosis on MDCT coronary angiography. H... Abstract

Cited 103 times since 2008 (5.8 per year) source: EuropePMC

Developmental dynamics : an official publication of the American Association of Anatomists, Volume 237, Issue 3, 1 1 2008, Pages 847-857 Cardiac malformations and myocardial abnormalities in podoplanin knockout mouse embryos: Correlation with abnormal epicardial development. Mahtab EA, Wijffels MC, Van Den Akker NM, Hahurij ND, Lie-Venema H, Wisse LJ, Deruiter MC, Uhrin P, Zaujec J, Binder BR, Schalij MJ, Poelmann RE, Gittenberger-De Groot AC

Epicardium and epicardium-derived cells have been shown to be necessary for myocardial differentiation. To elucidate the function of podoplanin in epicardial development and myocardial differentiation, we analyzed podoplanin knockout mouse embryos between embryonic day (E) 9.5 and E15.5 using immunohistochemical differentiation markers, morphometry, and three-dimensional reconstructions. Podoplanin null mice have an increased embryonic lethality, possibly of cardiac origin. Our study reveals imp... Abstract

Cited 66 times since 2008 (3.7 per year) source: EuropePMC

Diabetic medicine : a journal of the British Diabetic Association, Volume 25, Issue 3, 1 1 2008, Pages 277-281 Sulphonylurea therapy improves cognition in a patient with the V59M KCNJ11 mutation. Slingerland AS, Hurkx W, Noordam K, Flanagan SE, Jukema JW, Meiners LC, Bruining GJ, Hattersley AT, Hadders-Algra M

Background: KCNJ11 mutations are a common cause of diabetes diagnosed in the first 6 months of life, and approximately 25% of patients have neurological features. Sulphonylureas have been shown to improve glycaemic control and also motor function, but the impact on cognitive function has not been extensively addressed previously. Methods: The patient had a low birth weight and was found to have diabetes at the age of 2 days. The patient was treated with insulin from diagnosis. The child also had... Abstract

Cited 25 times since 2008 (1.4 per year) source: EuropePMC

Pacing and clinical electrophysiology : PACE, Volume 31, Issue 3, 1 1 2008, Pages 358-374 Ablation of ventricular tachycardia in patients with structural heart disease. Zeppenfeld K, Stevenson WG

Catheter ablation is an important therapeutic option for controlling recurrent ventricular arrhythmias in patients with heart disease. Although implantable defibrillators are generally first line therapy in this patient population, a substantial number of patients require additional therapy with either antiarrhythmic drugs, ablation, or both. Studies of mapping and ablation have produced further insights into pathophysiologic mechanisms of these arrhythmias, which are now well characterized. The... Abstract

Cited 354 times since 2008 (20 per year) source: EuropePMC

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, Volume 21, Issue 3, 1 1 2008, Pages 191-213 Echocardiography for cardiac resynchronization therapy: recommendations for performance and reporting--a report from the American Society of Echocardiography Dyssynchrony Writing Group endorsed by the Heart Rhythm Society. Gorcsan J, Abraham T, Agler DA, Bax JJ, Derumeaux G, Grimm RA, Martin R, Steinberg JS, Sutton MS, Yu CM, American Society of Echocardiography Dyssynchrony Writing Group, American Society of Echocardiography Dyssynchrony Writing Group, Heart Rhythm Society

Echocardiography plays an evolving and important role in the care of heart failure patients treated with biventricular pacing, or cardiac resynchronization therapy (CRT). Numerous recent published reports have utilized echocardiographic techniques to potentially aide in patient selection for CRT prior to implantation and to optimized device settings afterwards. However, no ideal approach has yet been found. This consensus report evaluates the contemporary applications of echocardiography for CRT... Abstract

Cited 27 times since 2008 (1.5 per year) source: EuropePMC

Heart (British Cardiac Society), Volume 94, Issue 3, 1 1 2008, Pages 255-257 CT angiography: an alternative to nuclear perfusion imaging? Schuijf JD, Bax JJ

Abstract

Cited 3 times since 2008 (0.2 per year) source: EuropePMC

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, Volume 15, Issue 2, 1 1 2008, Pages 218-224 Stroke volume measurements with first-pass dynamic positron emission tomography: comparison with cardiovascular magnetic resonance. Knaapen P, Lubberink M, Rijzewijk LJ, van der Meer RW, Unger M, Germans T, Bax JJ, Smit JW, Lamb HJ, van Rossum AC, Diamant M, Visser FC, Lammertsma AA

Background: The assessment of forward stroke volume (SV) using dynamic, first-pass cardiac positron emission tomography (PET) was shown to be feasible in a limited number of studies with small numbers of subjects. The aim of this study was to compare first-pass derived SV with cardiovascular magnetic resonance imaging (CMR)-obtained values in a larger population of subjects. Methods and results: Fifty-nine subjects with varying degrees of cardiac function were studied. Stroke volume was assessed... Abstract

Cited 37 times since 2008 (2.1 per year) source: EuropePMC

American journal of physiology. Heart and circulatory physiology, Volume 294, Issue 5, 29 5 2008, Pages H2150-7 Improved ECG detection of presence and severity of right ventricular pressure load validated with cardiac magnetic resonance imaging. Henkens IR, Mouchaers KT, Vonk-Noordegraaf A, Boonstra A, Swenne CA, Maan AC, Man SC, Twisk JW, van der Wall EE, Schalij MJ, Vliegen HW

The study aimed to assess whether the 12-lead ECG-derived ventricular gradient, a vectorial representation of ventricular action potential duration heterogeneity directed toward the area of shortest action potential duration, can improve ECG diagnosis of chronic right ventricular (RV) pressure load. ECGs from 72 pulmonary arterial hypertension patients recorded 1 with R > 0.5 mV in V1, and QRS axis >90 degrees ) had a sensitivity of 89% and a specificity of 93% for presence of chronic RV... Abstract

Cited 3 times since 2008 (0.2 per year) source: EuropePMC

Current medical research and opinion, Volume 24, Issue 4, 28 4 2008, Pages 1065-1068 Determinants of CRP level in statin-treated patients. Liem AH, van de Woestijne AP, Zwinderman AH, Visseren FL, Jukema JW

Objective: All factors of the metabolic syndrome (MetS) are reported to be associated with elevated C-reactive protein (CRP) levels. As CRP levels have been found to decrease as a result of statin treatment, the present study was intended to explore the relationship between CRP and the MetS in statin treated patients. Methods: In this study, the relationship between the components of the MetS and CRP level were analysed and factors determining CRP were identified in patients with longstanding in... Abstract

Cited 86 times since 2008 (4.9 per year) source: EuropePMC

European heart journal, Volume 29, Issue 6, 27 4 2008, Pages 757-765 Mechanism of improvement in mitral regurgitation after cardiac resynchronization therapy. Ypenburg C, Lancellotti P, Tops LF, Boersma E, Bleeker GB, Holman ER, Thomas JD, Schalij MJ, Piérard LA, Bax JJ

Aims: The aim of the current study was to evaluate the relationship between the presence of left ventricular (LV) dyssynchrony at baseline and acute vs. late improvement in mitral regurgitation (MR) after cardiac resynchronization therapy (CRT). Methods and results: Sixty eight patients consecutive (LV ejection fraction 23 +/- 8%) with at least moderate MR (>or=grade 2+) were included. Echocardiography was performed at baseline, 1 day after CRT initiation and at 6 months follow-up. Speckle tr... Abstract

Cited 41 times since 2008 (2.3 per year) source: EuropePMC

British journal of anaesthesia, Volume 100, Issue 4, 26 4 2008, Pages 525-532 Covariates of tramadol disposition in the first months of life. Allegaert K, van den Anker JN, de Hoon JN, van Schaik RH, Debeer A, Tibboel D, Naulaers G, Anderson BJ

Background: Data on contributors to between-individual variability in overall tramadol clearance and O-demethyl tramadol (M1) formation in preterm neonates and young infants are limited. Methods: A population pharmacokinetic analysis of tramadol and M1 was undertaken using non-linear mixed effects model. Covariate analysis included weight, postmenstrual age (PMA), postnatal age (PNA), creatinaemia, (cardiac) surgery, cardiac defect, and cytochrome (CYP)2D6 polymorphisms, classified by CYP2D6 act... Abstract

Cited 55 times since 2008 (3.1 per year) source: EuropePMC

Brain : a journal of neurology, Volume 131, Issue Pt 4, 26 4 2008, Pages 1069-1077 Genetic variation in the interleukin-1 beta-converting enzyme associates with cognitive function. The PROSPER study. Trompet S, de Craen AJ, Slagboom P, Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Ford I, Gaw A, Macfarlane PW, Packard CJ, Stott DJ, Jukema JW, Westendorp RG, PROSPER Group

Inflammation is thought to play an important role in the development of cognitive decline and dementia in old age. The interleukin-1 signalling pathway may play a prominent role in this process. The gene encoding for interleukin-1 beta-converting enzyme (ICE) is likely to influence IL-1 beta levels. Inhibition of ICE decreases the age-related increase in IL-1 beta levels and may therefore improve memory function. We assessed whether genetic variation in the ICE gene associates with cognitive fun... Abstract

Cited 40 times since 2008 (2.3 per year) source: EuropePMC

Differentiation; research in biological diversity, Volume 76, Issue 7, 21 3 2008, Pages 809-819 Periostin expression by epicardium-derived cells is involved in the development of the atrioventricular valves and fibrous heart skeleton. Lie-Venema H, Eralp I, Markwald RR, van den Akker NM, Wijffels MC, Kolditz DP, van der Laarse A, Schalij MJ, Poelmann RE, Bogers AJ, Gittenberger-de Groot AC

The epicardium is embryologically formed by outgrowth of proepicardial cells over the naked heart tube. Epicardium-derived cells (EPDCs) migrate into the myocardium, contributing to myocardial architecture, valve development, and the coronary vasculature. Defective EPDC formation causes valve malformations, myocardial thinning, and coronary defects. In the atrioventricular (AV) valves and the fibrous heart skeleton isolating atrial from ventricular myocardium, EPDCs colocalize with periostin, a... Abstract

Cited 106 times since 2008 (6 per year) source: EuropePMC

Journal of human evolution, Volume 55, Issue 1, 13 2 2008, Pages 60-74 Functional ecology and evolution of hominoid molar enamel thickness: Pan troglodytes schweinfurthii and Pongo pygmaeus wurmbii. Vogel ER, van Woerden JT, Lucas PW, Utami Atmoko SS, van Schaik CP, Dominy NJ

The divergent molar characteristics of Pan troglodytes and Pongo pygmaeus provide an instructive paradigm for examining the adaptive form-function relationship between molar enamel thickness and food hardness. Although both species exhibit a categorical preference for ripe fruit over other food objects, the thick enamel and crenulated occlusal surface of Pongo molar teeth predict a diet that is more resistant to deformation (hard) and fracture (tough) than the diet of Pan. We confirm these predi... Abstract

Cited 7 times since 2008 (0.4 per year) source: EuropePMC

International journal of oral and maxillofacial surgery, Volume 37, Issue 5, 12 2 2008, Pages 448-452 Biomechanical evaluation of the consolidation period of alveolar distraction osteogenesis with three-dimensional finite element analysis. Veziroglu F, Yilmaz D

In this study, three-dimensional (3D) modeling and finite element analysis were used to determine the optimum consolidation period for implant loading under forces of different directions and amounts after alveolar distraction osteogenesis. A 3D model of an atrophic edentulous alveolar crest was prepared. Distraction osteogenesis with the required bone height was simulated. After a consolidation period of 4, 8, 12 and 16 weeks, horizontal, vertical and oblique forces were applied to the conical... Abstract