Publications
Below you can find a list of our published research.
Below you can find a list of our published research.
6177 results
Cited 2 times since 2024 (3.6 per year) source: EuropePMC
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Volume 66, Issue 4, 1 1 2024, Pages ezae339 European Association of Cardiothoracic Surgeons future view on robotic cardiac surgery in Europe. Oosterlinck W, Gianoli M, Palmen M, Folliguet T, Bonatti J, Agnino A, Singh S, Franke U, Modi P, Pereda D, Kempfert J, Navarra E, Suwalski P, Vojacek J, Casselman F, Myers P, Sadaba JR, Melfi F, Hazekamp M, Bavaria J, Beyersdorf F, Milojevic M, Falk V, Cerny S
Cited 5 times since 2024 (8.9 per year) source: EuropePMC
Brain communications, Volume 6, Issue 5, 1 1 2024, Pages fcae309 Sudden death in epilepsy: the overlap between cardiac and neurological factors. Shlobin NA, Thijs RD, Benditt DG, Zeppenfeld K, Sander JW
People with epilepsy are at risk of premature death, of which sudden unexpected death in epilepsy (SUDEP), sudden cardiac death (SCD) and sudden arrhythmic death syndrome (SADS) are the primary, partly overlapping, clinical scenarios. We discuss the epidemiologies, risk factors and pathophysiological mechanisms for these sudden death events. We reviewed the existing evidence on sudden death in epilepsy. Classification of sudden death depends on the presence of autopsy and expertise of the clinic... Abstract
European heart journal. Imaging methods and practice, Volume 2, Issue 4, 1 1 2024, Pages qyaf033 Factors affecting the performance of a novel artificial intelligence-based coronary computed tomography-derived ischaemia algorithm. Kiatkittikul P, Maaniitty T, Bär S, Nabeta T, Bax JJ, Saraste A, Knuuti J
Aims: AI-QCTischaemia is an FDA-cleared novel artificial intelligence-guided method that utilizes features from coronary computed tomography angiography (CCTA) to predict myocardial ischaemia. Objective: To identify factors associated with discrepancy between AI-QCTischaemia and positron emission tomography (PET) perfusion. Methods and results: Six hundred and sixty-two patients with suspected obstructive coronary artery disease (CAD) on CCTA and undergoing [15O]H2O PET were analysed using AI-QC... Abstract
Cited 3 times since 2024 (5.3 per year) source: EuropePMC
JAMA dermatology, Volume 160, Issue 10, 1 1 2024, Pages 1044-1055 Long-Term Effectiveness and Reasons for Discontinuation of Dupilumab in Patients With Atopic Dermatitis. Boesjes CM, Kamphuis E, de Graaf M, Spekhorst LS, Haeck I, van der Gang LF, Loman L, Zuithoff NPA, Dekkers C, van der Rijst LP, Romeijn GLE, Oosting AJ, Gostynksi A, van Lynden-van Nes AMT, Tupker RA, van Tuyll van Serooskerken AM, Flinterman A, Politiek K, Touwslager WRH, Christoffers WA, Stewart SM, Kamsteeg M, Schuttelaar MA, de Bruin-Weller MS
Importance: Limited data are available on the long-term effectiveness and safety of dupilumab for atopic dermatitis (AD) in daily practice. Objective: To evaluate clinical effectiveness and reasons for discontinuation of dupilumab treatment in children, adults, and older adults with AD with up to 5 years of treatment in daily practice. Design, setting, and participants: This prospective multicenter cohort study was conducted using the BioDay registry (4 academic and 10 nonacademic hospitals in t... Abstract
Cited 2 times since 2024 (3.6 per year) source: EuropePMC
European journal of preventive cardiology, Volume 31, Issue 14, 1 1 2024, Pages 1690-1699 Prediction of individual lifetime cardiovascular risk and potential treatment benefit: development and recalibration of the LIFE-CVD2 model to four European risk regions. Hageman SHJ, Kaptoge S, de Vries TI, Lu W, Kist JM, van Os HJA, Numans ME, Läll K, Bobak M, Pikhart H, Kubinova R, Malyutina S, Pająk A, Tamosiunas A, Erbel R, Stang A, Schmidt B, Schramm S, Bolton TR, Spackman S, Bakker SJL, Blaha M, Boer JMA, Bonnefond A, Brenner H, Brunner EJ, Cook NR, Davidson K, Dennison E, Donfrancesco C, Dörr M, Floyd JS, Ford I, Fu M, Gansevoort RT, Giampaoli S, Gillum RF, Gómez-de-la-Cámara A, Håheim LL, Hansson PO, Harms P, Humphries SE, Ikram MK, Jukema JW, Kavousi M, Kiechl S, Kucharska-Newton A, Pablos DL, Matsushita K, Meyer HE, Moons KGM, Mortensen MB, Muilwijk M, Nordestgaard BG, Packard C, Pamieri L, Panagiotakos D, Peters A, Potier L, Providencia R, Psaty BM, Ridker PM, Rodriguez B, Rosengren A, Sattar N, Schöttker B, Schwartz JE, Shea S, Shipley MJ, Sofat R, Thorand B, Verschuren WMM, Völzke H, Wareham NJ, Westbury L, Willeit P, Zhou B, Danesh J, Visseren FLJ, Di Angelantonio E, Pennells L, Dorresteijn JAN
Aims: The 2021 European Society of Cardiology prevention guidelines recommend the use of (lifetime) risk prediction models to aid decisions regarding initiation of prevention. We aimed to update and systematically recalibrate the LIFEtime-perspective CardioVascular Disease (LIFE-CVD) model to four European risk regions for the estimation of lifetime CVD risk for apparently healthy individuals. Methods and results: The updated LIFE-CVD (i.e. LIFE-CVD2) models were derived using individual partici... Abstract
Echocardiography (Mount Kisco, N.Y.), Volume 41, Issue 10, 1 1 2024, Pages e70006 Evolution and Prognostic Impact of Left Ventricular Myocardial Work Indices After Transcatheter Aortic Valve Replacement in Patients With Severe Aortic Stenosis. Wu HW, Fortuni F, Muzafarova T, Sarrazyn C, Lopez Santi P, Chua APA, Butcher SC, van der Kley F, de Weger A, Jukema JW, Bax JJ, Ajmone Marsan N
Purpose: Left ventricular myocardial work (LVMW) has been shown to better characterize LV function in patients with severe aortic stenosis by correcting LV afterload. The aim of this study was to evaluate the evolution in LVMW indices after transcatheter aortic valve replacement (TAVR) and their prognostic value. Methods: The following LVMW indices were calculated before and immediately after TAVR in 255 patients (median age 82 years, 51% male): global work index (GWI), global constructive work... Abstract
Cells, Volume 13, Issue 19, 30 5 2024, Pages 1636 Pulmonary and Systemic Immune Profiles Following Lung Volume Reduction Surgery and Allogeneic Mesenchymal Stromal Cell Treatment in Emphysema. Jia L, Li N, van Unen V, Zwaginga JJ, Braun J, Hiemstra PS, Koning F, Khedoe PPSJ, Stolk J
Emphysema in patients with chronic obstructive pulmonary disease (COPD) is characterized by progressive inflammation. Preclinical studies suggest that lung volume reduction surgery (LVRS) and mesenchymal stromal cell (MSC) treatment dampen inflammation. We investigated the effects of bone marrow-derived MSC (BM-MSC) and LVRS on circulating and pulmonary immune cell profiles in emphysema patients using mass cytometry. Blood and resected lung tissue were collected at the first LVRS (L1). Following... Abstract
Cited 1 times since 2024 (1.7 per year) source: EuropePMC
JACC. Clinical electrophysiology, Volume 10, Issue 12, 25 4 2024, Pages 2613-2624 Ventricular Tachycardia Substrates in Children and Young Adults With Repaired Tetralogy of Fallot. Wallet J, Kimura Y, Blom NA, Jongbloed MRM, Bertels RA, Hazekamp MG, Zeppenfeld K
Background: Patients with repaired tetralogy of Fallot (rTOF) have a time-dependent increased risk of ventricular tachycardia (VT). Slow conducting anatomical isthmuses (SCAIs) are the dominant VT substrates in adults with rTOF. It is unknown if they are present at younger age. Objectives: This study aimed to characterize VT substrates in patients with rTOF Abstract
Cited 1 times since 2024 (1.7 per year) source: EuropePMC
European journal of heart failure, 24 4 2024 Sexual dimorphism in the relationships between intramyocardial fat, myocardial fibrosis, and exercise intolerance in heart failure with preserved ejection fraction. Ng ACT, Dong X, Koepp KE, Obokata M, Sorimachi H, Galloway G, Araoz P, Delgado V, Bax JJ, Borlaug BA
Biosensors & bioelectronics, Volume 267, 24 4 2024, Pages 116791 Dual action electrochemical bandage operated by a programmable multimodal wearable potentiostat. Bozyel I, Fleming D, Won-Jun K, Rosen PF, Gelston S, Ozdemir D, Kies P, Koscianski C, Karau M, Ay SU, Patel R, Beyenal H
We have developed electrochemical bandage (e-bandage) prototypes that generate the reactive oxygen species hypochlorous acid (HOCl) or hydrogen peroxide (H2O2) for potential use to treat biofilm-infected wounds in humans. We have shown that both e-bandage-generated HOCl and H2O2 kill biofilms in vitro and in infected wounds on mice, with the former being more active in vitro. The H2O2-generating e-bandage, more so than the HOCl-generating e-bandage, was associated with improved healing of infect... Abstract
Cited 1 times since 2024 (1.7 per year) source: EuropePMC
Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, Volume 104, Issue 5, 23 4 2024, Pages 881-890 Procedural and clinical impact of intracoronary lithotripsy in heavily calcified aorto-ostial coronary lesions. Oliveri F, Meijer M, Van Oort MJH, Al Amri I, Bingen BO, Claessen BE, Dimitriu-Leen AC, Kefer J, Girgis H, Vossenberg T, Van der Kley F, Jukema JW, Montero-Cabezas JM
Background: Percutaneous coronary intervention of calcified aorto-ostial lesions (AOL) pose unique challenges due to anatomical propensity for recoil, leading to poorer outcomes compared to non-AOL. Although intravascular lithotripsy (IVL) has shown excellent success and safety in heavily calcified plaques, evidence specific to AOL is limited. This study aims to evaluate the efficacy and safety of IVL in AOL versus non-AOL. Methods: Patients treated with IVL between 2019 and 2023 from an ongoing... Abstract
Cited 10 times since 2024 (17.1 per year) source: EuropePMC
Circulation, Volume 150, Issue 24, 23 4 2024, Pages 1931-1943 Interatrial Shunt Treatment for Heart Failure: The Randomized RELIEVE-HF Trial. Stone GW, Lindenfeld J, Rodés-Cabau J, Anker SD, Zile MR, Kar S, Holcomb R, Pfeiffer MP, Bayes-Genis A, Bax JJ, Bank AJ, Costanzo MR, Verheye S, Roguin A, Filippatos G, Núñez J, Lee EC, Laufer-Perl M, Moravsky G, Litwin SE, Prihadi E, Gada H, Chung ES, Price MJ, Thohan V, Schewel D, Kumar S, Kische S, Shah KS, Donovan DJ, Zhang Y, Eigler NL, Abraham WT, RELIEVE-HF Investigators
Background: An interatrial shunt may provide an autoregulatory mechanism to decrease left atrial pressure and improve heart failure (HF) symptoms and prognosis. Methods: Patients with symptomatic HF with any left ventricular ejection fraction (LVEF) were randomized 1:1 to transcatheter shunt implantation versus a placebo procedure, stratified by reduced (≤40%) versus preserved (>40%) LVEF. The primary safety outcome was a composite of device-related or procedure-related major adverse cardiova... Abstract
European heart journal open, Volume 4, Issue 5, 23 4 2024, Pages oeae080 Short-term impact of cardiovascular screening by traditional risk assessment or coronary artery calcium score on health-related quality of life: the ROBINSCA trial. Moldovanu D, de Koning HJ, Vonder M, Gratama JWC, Adriaansen HJ, Roeters van Lennep JE, Vliegenthart R, van der Harst P, Braam RL, van Dijkman PRM, Oudkerk M, van der Aalst CM
Aims: Evidence on the impact of screening for cardiovascular diseases (CVDs) on health-related quality of life (HRQoL) is important for policy decisions about screening implementation and to uncover teachable moments to motivate healthy lifestyle choices. It is unknown whether screening by cardiac computed tomography (CT) scan has a stronger impact on HRQoL than screening by traditional risk prediction models. The study aims to investigate differences in HRQoL across the screening process betwee... Abstract
Cited 1 times since 2024 (1.7 per year) source: EuropePMC
Heart & lung : the journal of critical care, Volume 69, 17 3 2024, Pages 31-39 Modifiable risk factors and motivation for lifestyle change of CVD patients starting cardiac rehabilitation: The BENEFIT study. Breeman LD, Pérez-Alonso A, Kühling-Romero D, Kraaijenhagen RA, Al-Dhahir I, IJzerman RVH, van Eersel R, Wolstencroft K, Bonten TN, Atsma DE, Chavannes NH, van Gemert-Pijnen L, Kemps HMC, Scholte Op Reimer W, Evers AWM, Janssen VR, BENEFIT consortium
Background: To improve lifestyle guidance within cardiac rehabilitation (CR), a comprehensive understanding of the motivation and lifestyle-supporting needs of patients with cardiovascular disease (CVD) is required. Objectives: This study's purpose is to evaluate patients' lifestyle and their motivation, self-efficacy and social support for change when starting CR. Methods: 1782 CVD patients (69 % male, mean age 62 years) from 7 Dutch outpatient CR centers participated between 2020 and... Abstract
Research and practice in thrombosis and haemostasis, Volume 8, Issue 7, 16 3 2024, Pages 102573 The impact of pulmonary embolism on health outcomes of COVID-19 at 3 months after hospitalization. Visser C, Berentschot JC, de Jong CMM, Antoni ML, Bek LM, van den Berg-Emons RJG, van den Borst B, Ten Cate H, Ten Cate-Hoek AJ, Braeken DCW, Geelhoed JJM, Heijenbrok-Kal MH, van Kuijk SMJ, Kroft LJM, Leentjens J, Roukens AHE, Cannegieter SC, Klok FA, Kruip MJHA, Hellemons ME, Dutch COVID & Thrombosis Coalition@CovidDutch
Background: COVID-19 patients frequently experience pulmonary embolism (PE), but its long-term consequences remain uncertain. Objectives: To assess the impact of PE in COVID-19 patients on health outcomes at 3 months after hospitalization. Methods: In this multicenter cross-sectional study, we aggregated data from existing databases to evaluate the impact of PE on health outcomes at 3 months after hospitalization. We assessed 1) questionnaires on health-related quality of life (5-level EuroQol 5... Abstract
Cited 3 times since 2024 (5 per year) source: EuropePMC
Nature medicine, Volume 30, Issue 11, 16 3 2024, Pages 3223-3235 Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial. Nederlof I, Isaeva OI, de Graaf M, Gielen RCAM, Bakker NAM, Rolfes AL, Garner H, Boeckx B, Traets JJH, Mandjes IAM, de Maaker M, van Brussel T, Chelushkin M, Champanhet E, Lopez-Yurda M, van de Vijver K, van den Berg JG, Hofland I, Klioueva N, Mann RM, Loo CE, van Duijnhoven FH, Skinner V, Luykx S, Kerver E, Kalashnikova E, van Dongen MGJ, Sonke GS, Linn SC, Blank CU, de Visser KE, Salgado R, Wessels LFA, Drukker CA, Schumacher TN, Horlings HM, Lambrechts D, Kok M
Immune checkpoint inhibition (ICI) with chemotherapy is now the standard of care for stage II-III triple-negative breast cancer; however, it is largely unknown for which patients ICI without chemotherapy could be an option and what the benefit of combination ICI could be. The adaptive BELLINI trial explored whether short combination ICI induces immune activation (primary end point, twofold increase in CD8+ T cells or IFNG), providing a rationale for neoadjuvant ICI without chemotherapy. Here, in... Abstract
Cited 3 times since 2024 (4.9 per year) source: EuropePMC
Communications biology, Volume 7, Issue 1, 13 2 2024, Pages 1135 Nucleolus and centromere Tyramide Signal Amplification-Seq reveals variable localization of heterochromatin in different cell types. Kumar P, Gholamalamdari O, Zhang Y, Zhang L, Vertii A, van Schaik T, Peric-Hupkes D, Sasaki T, Gilbert DM, van Steensel B, Ma J, Kaufman PD, Belmont AS
Genome differential positioning within interphase nuclei remains poorly explored. We extended and validated Tyramide Signal Amplification (TSA)-seq to map genomic regions near nucleoli and pericentric heterochromatin in four human cell lines. Our study confirmed that smaller chromosomes localize closer to nucleoli but further deconvolved this by revealing a preference for chromosome arms below 36-46 Mbp in length. We identified two lamina associated domain subsets through their differential nucl... Abstract
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, Volume 68, Issue 6, 11 2 2024, Pages 815-816 Editor's Choice - Radiation Protection and Pregnancy in Vascular Surgery and Interventional Radiology in the Netherlands. Jongen JMJ, Samim M, Hoornstra KJPC, Eefting D, van Herwaarden JA, Blok JJ
Cited 1 times since 2024 (1.6 per year) source: EuropePMC
Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, Volume 32, Issue 10, 10 2 2024, Pages 338-345 2023 European Society of Cardiology guidelines for the management of acute coronary syndromes : Statement of endorsement by the NVVC. Zwart B, Claessen BEPM, Damman P, Woudstra P, Vink MA, Balder JW, Dickinson MG, Badings EA, Appelman Y, van 't Hof AWJ, Ten Berg JM, Arslan F
This review discusses the new recommendations in the 2023 European Society of Cardiology guidelines on the management of acute coronary syndrome and provides a perspective on topics specific to clinical practice in the Netherlands, including pre-treatment, antiplatelet agent strategies, the use of risk scores and logistical considerations with regard to the timing of coronary angiography. Abstract
Atherosclerosis, Volume 398, 7 1 2024, Pages 118595 Arterial inflammation on [<sup>18</sup>F]FDG PET/CT in melanoma patients treated with and without immune checkpoint inhibitors: CHECK-FLAME I. Polomski EAS, Kapiteijn EW, Heemelaar JC, van der Kolk AV, Kalisvaart TM, van de Burgt A, Dibbets-Schneider P, van Velden FHP, Seijkens TTP, Stöger JL, Jukema JW, de Geus-Oei LF, Antoni ML
Background and aims: Immune checkpoint inhibitors (ICIs) revolutionized cancer treatment. However, ICIs may increase the immune response to non-tumor cells, possibly resulting in increased arterial inflammation, raising the risk of atherosclerotic events. Nevertheless, malignancies may induce a pro-inflammatory state and the association between ICIs and arterial inflammation remains to be clarified. This study aims to assess differences in increase in arterial inflammation between patients with... Abstract