6177 results
Cited 8 times since 2024 (11.5 per year)
source: EuropePMC
The lancet. Gastroenterology & hepatology,
Volume 9, Issue 10, 13 2 2024, Pages 924-934
Indocyanine green near-infrared fluorescence bowel perfusion assessment to prevent anastomotic leakage in minimally invasive colorectal surgery (AVOID): a multicentre, randomised, controlled, phase 3 trial.
Faber RA, Meijer RPJ, Droogh DHM, Jongbloed JJ, Bijlstra OD, Boersma F, Braak JPBM, Meershoek-Klein Kranenbarg E, Putter H, Holman FA, Mieog JSD, Neijenhuis PA, van Staveren E, Bloemen JG, Burger JWA, Aukema TS, Brouwers MAM, Marinelli AWKS, Westerterp M, Doornebosch PG, van der Weijde A, Bosscha K, Handgraaf HJM, Consten ECJ, Sikkenk DJ, Burggraaf J, Keereweer S, van der Vorst JR, Hutteman M, Peeters KCMJ, Vahrmeijer AL, Hilling DE
Background: Anastomotic leakage is a severe postoperative complication in colorectal surgery and compromised bowel perfusion is considered a major contributing factor. Conventional methods to assess bowel perfusion have a low predictive value for anastomotic leakage. We therefore aimed to evaluate the efficacy of real-time assessment with near-infrared (NIR) fluorescence imaging with indocyanine green (ICG) in the prevention of anastomotic leakage. Methods: This multicentre, randomised, controll...
Abstract
Cited 1 times since 2024 (1.4 per year)
source: EuropePMC
Antimicrobial agents and chemotherapy,
Volume 68, Issue 9, 13 2 2024, Pages e0065024
Bacteriophage therapy reduces <i>Staphylococcus aureus</i> in a porcine and human <i>ex vivo</i> burn wound infection model.
Molendijk MM, Boekema BKHL, Lattwein KR, Vlig M, Bode LGM, Koopmans MPG, Verbon A, de Graaf M, van Wamel WJB
Burn wounds are a major burden, with high mortality rates due to infections. Staphylococcus aureus is a major causative agent of burn wound infections, which can be difficult to treat because of antibiotic resistance and biofilm formation. An alternative to antibiotics is the use of bacteriophages, viruses that infect and kill bacteria. We investigated the efficacy of bacteriophage therapy for burn wound infections, in both a porcine and a newly developed human ex vivo skin model. In both models...
Abstract
Journal of thoracic disease,
Volume 16, Issue 8, 13 2 2024, Pages 4914-4923
Deep learning to predict long-term mortality from plain chest X-ray in patients referred for suspected coronary artery disease.
D'Ancona G, Savardi M, Massussi M, Van Der Valk V, Scherptong RWC, Signoroni A, Farina D, Murero M, Ince H, Benussi S, Curello S, Arslan F
Background: The hypothesis that a deep learning (DL) model can produce long-term prognostic information from chest X-ray (CXR) has already been confirmed within cancer screening programs. We summarize our experience with DL prediction of long-term mortality, from plain CXR, in patients referred for angina and coronary angiography. Methods: Data of patients referred to an Italian academic hospital were analyzed retrospectively. We designed a deep convolutional neural network (DCNN) that, from CXR...
Abstract
Cited 1 times since 2024 (1.4 per year)
source: EuropePMC
Journal of cardiovascular electrophysiology,
Volume 35, Issue 10, 8 2 2024, Pages 1972-1980
Characterization of atrial arrhythmias following mitral valve repair: Incidence and risk factors.
El Mathari S, Tomšič A, Kharbanda RK, Zappala P, Wijnmaalen AP, Klautz RJM, Silva MR, Palmen M
Objectives: This study aims to investigate the occurrence, type and correlation of early and late atrial arrhythmias following mitral valve repair in patients with no preoperative history of atrial arrhythmias. Methods: Patients undergoing mitral valve (MV) repair for degenerative disease were included. Early and late postoperative electrocardiograms were evaluated for the incidence and type of atrial arrhythmia (atrial fibrillation [AF] or atrial tachycardia [AT]). Results: The 192 patients wer...
Abstract
Future oncology (London, England),
Volume 20, Issue 27, 5 1 2024, Pages 2015-2022
Expression of integrin α<sub>v</sub>β<sub>3</sub> in medullary thyroid carcinoma.
de Vries LH, Lodewijk L, Pijnappel EW, van Diest PJ, Schepers A, Bonenkamp HJ, van Engen-van Grunsven IA, Kruijff S, van Hemel BM, Links TP, Nieveen van Dijkum EJ, van Eeden S, van Leeuwaarde RS, Valk GD, de Keizer B, Borel Rinkes IH, Vriens MR
Aim: Tumor markers often remain elevated after intended curative resection of medullary thyroid carcinoma (MTC). The aim of this study was to determine the expression of αvβ3, a promising theranostics target, in MTC and its metastases.Materials & methods: Avβ3 expression was analyzed in 104 patients using a tissue microarray and correlated with clinicopathological variables and survival.Results: Cytoplasmic αvβ3 positivity was seen in 70 patients and was associated with lymph node metastases...
Abstract
Journal of electrocardiology,
Volume 86, 5 1 2024, Pages 153768
Rationale and design of the artificial intelligence scalable solution for acute myocardial infarction (ASSIST) study.
Domingo-Gardeta T, Montero-Cabezas JM, Jurado-Román A, Sabaté M, Aboal J, Baranchuk A, Carrillo X, García-Zamora S, Dores H, van der Valk V, Scherptong RWC, Andrés-Cordón JF, Vidal P, Moreno-Martínez D, Toribio-Fernández R, Lillo-Castellano JM, Cruz R, De Guio F, Marina-Breysse M, Martínez-Sellés M
Background: Acute coronary syndrome (ACS), specifically ST-segment elevation myocardial infarction is a major cause of morbidity and mortality throughout Europe. Diagnosis in the acute setting is mainly based on clinical symptoms and physician's interpretation of an electrocardiogram (ECG), which may be subject to errors. ST-segment elevation is the leading criteria to activate urgent reperfusion therapy, but a clear ST-elevation pattern might not be present in patients with coronary occlus...
Abstract
International journal of cardiology,
Volume 415, 3 1 2024, Pages 132421
CIED-based remote monitoring in heart failure using the HeartLogic™ algorithm: Which patients benefit most?
van der Lande ACMH, Feijen M, Egorova AD, Beles M, van Bockstal K, Phagu AAS, Schalij MJ, Heggermont WA, Beeres SLMA
Background & aims: Early identification of worsening HF enables timely adjustments to prevent hospitalization. Recent studies show the HeartLogic™ algorithm detects congestion and reduces HF events. However, it is unclear which patients benefit most. Therefore, this study aims to identify and characterize HF patients who benefit most from CIED-based remote monitoring with HeartLogic™. Methods: In this multicenter retrospective study, patients with a CIED and HeartLogic™ algorithm under struc...
Abstract
Cited 1 times since 2024 (1.4 per year)
source: EuropePMC
International journal of cardiology,
Volume 414, 3 1 2024, Pages 132414
The prognostic value of changes in pulmonary vein flow patterns after surgical repair for primary mitral regurgitation.
Yedidya I, Stassen J, Butcher S, van Wijngaarden AL, Wu Y, van der Bijl P, Marsan NA, Delgado V, Bax J
Background: The pulmonary vein (PV) flow pattern is influenced by the presence of mitral regurgitation (MR). After a successful reduction in MR severity, the pattern is expected to be changed. We aimed to evaluate the prognostic value of a change in the PV flow pattern in patients with primary MR undergoing mitral valve repair (MVR). Methods: The PV flow pattern was assessed with transthoracic echocardiography in 216 patients (age 65 [IQR 56-72] years, 70% male) with primary MR before and after...
Abstract
Cited 1 times since 2024 (1.4 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 25, Issue 9, 1 1 2024, Pages 1296-1305
Structural and functional abnormalities of left-sided cardiac chambers in Barlow's disease without significant mitral regurgitation.
Meucci MC, Mantegazza V, Wu HW, van Wijngaarden AL, Garlaschè A, Tamborini G, Pepi M, Bax JJ, Ajmone Marsan N
Aims: This study aims to explore the presence of left ventricular (LV) and left atrial (LA) morphological and functional abnormalities in patients with Barlow's disease (BD) without significant mitral regurgitation (MR) and to investigate whether these abnormalities may predict MR progression. Methods and results: Consecutive patients with BD were retrospectively identified from two tertiary centres; those with MR graded from trivial to mild-to-moderate were selected and matched with health...
Abstract
Aorta (Stamford, Conn.),
Volume 12, Issue 4, 1 1 2024, Pages 86-93
The TRAIN Health Awareness Clinical Trial: Baseline Findings and Cardiovascular Risk Management in Aortic Dissection Patients.
Bacour N, Grewal S, Tirpan AU, Theijse R, Erp OV, Klautz RJM, Sakalihasan N, Hultgren R, Grewal N
Acute Type A aortic dissection (ATAAD) is a life-threatening condition requiring timely surgical intervention. Despite successful surgery, postoperative outcomes are frequently suboptimal due to the high frequency of cardiovascular risk factors. This study examines baseline cardiovascular risk factors in a population of ATAAD patients in the Netherlands. Additionally, this study outlines the protocol for a randomized controlled trial, designed to improve postoperative management.Baseline data we...
Abstract
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology,
Volume 35, Issue 8, 1 1 2024, Pages e14222
Reply to Sujoy Khan.
van der Rijst LP, de Winter-de Groot KM, de Bruin-Weller MS, de Graaf M
Abstract
Cited 1 times since 2024 (1.4 per year)
source: EuropePMC
European journal of preventive cardiology,
Volume 31, Issue 10, 1 1 2024, Pages e75-e78
Comparison of change in lipoprotein(a) mass and molar concentrations by alirocumab and risk of subsequent cardiovascular events in ODYSSEY OUTCOMES.
Szarek M, Reijnders E, Steg PG, Jukema JW, Schwertfeger M, Bhatt DL, Bittner VA, Diaz R, Fazio S, Garon G, Goodman SG, Harrington RA, White HD, Zeiher AM, Cobbaert C, Schwartz GG
Abstract
Heart rhythm,
Volume 22, Issue 2, 31 5 2024, Pages 536-543
ECTOPIC trial: The efficacy of flEcainide Compared To metOprolol in reducing Premature ventrIcular Contractions: A randomized open-label crossover study in pediatric patients.
Bertels RA, Kammeraad JAE, van Geloven N, Filippini LH, van der Palen RLF, Tak RO, Frerich S, Vanagt W, Rehbock JJB, Knobbe I, Kuipers IM, de Riva M, Zeppenfeld K, Blom NA
Background: Frequent premature ventricular contractions (PVCs) in children are usually considered benign. Symptoms and left ventricular dysfunction are indications for treatment with antiarrhythmic drugs. Objective: This study aimed to evaluate the efficacy of flecainide vs metoprolol in reducing PVCs in children. Methods: A randomized open-label crossover trial was conducted of children with a PVC burden of >15% on Holter monitoring successively treated with metoprolol and flecainide, or vic...
Abstract
International archives of allergy and immunology,
Volume 185, Issue 11, 30 5 2024, Pages 1074-1082
Dog Allergy in Children: A Single-Centered Study.
Büyük Yaytokgil Ş, Alim Aydın S, Yilmaz D, Şengül Emeksiz Z, Gülseren SC, Toyran M, Civelek E, Dibek Misirlioğlu E
Introduction: Dogs are among the most commonly allergenic pets for children. Data on risk factors for the development of dog allergy are scarce. This study aimed to evaluate the characteristics of children with dog allergy and identify predictors of symptom development with dog exposure. Methods: The study included children with dog allergen sensitization demonstrated by skin prick test (SPT) between September 1, 2019, and December 1, 2022. Demographic, clinical, and laboratory data were collect...
Abstract
Cited 1 times since 2024 (1.4 per year)
source: EuropePMC
FEBS open bio,
Volume 14, Issue 10, 28 4 2024, Pages 1668-1681
Daily rhythms in metabolic and locomotor behaviour of prematurely ageing PolgA mice.
Singh A, Yilmaz D, Wehrle E, Kuhn GA, Müller R
Ageing is an inherent and intricate biological process that takes place in living organisms as time progresses. It involves the decline of multiple physiological functions, leading to body structure and overall performance modifications. The ageing process differs among individuals and is influenced by various factors, including lifestyle, environment and genetic makeup. Metabolic changes and reduced locomotor activity are common hallmarks of ageing. Our study focuses on exploring these phenomen...
Abstract
Cited 1 times since 2024 (1.3 per year)
source: EuropePMC
Journal of clinical lipidology,
Volume 18, Issue 6, 27 4 2024, Pages e915-e925
The impact of statin use on sepsis mortality.
Li M, Noordam R, Trompet S, Winter EM, Jukema JW, Arbous MS, Rensen PCN, Kooijman S
Background: Statins exert pleiotropic anti-inflammatory and antioxidant effects in addition to their cholesterol-lowering properties. This study aimed to investigate whether statin use is associated with improved outcomes of sepsis. Methods: Data from patients with sepsis were extracted from the Medical Information Mart for Intensive Care IV database. Patients with a history of receiving prescriptions for statins (i.e., atorvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, or simvas...
Abstract
Cited 1 times since 2024 (1.3 per year)
source: EuropePMC
Annals of vascular surgery,
Volume 108, 25 4 2024, Pages 385-392
Prognostic Performance of the Maximal Systolic Acceleration at the Hallux in Healing of Foot Ulcers: A Retrospective Cohort Study.
Willems SA, Pruim JD, van der Vorst JR, van Schaik J, Schepers A, Hamming JF, Brouwers JJWM
Background: The accurate prediction of foot ulcer healing remains a major challenge in clinical practice. To date, no reliable bedside tests are available. The primary aim of this study was to determine the prognostic performance of the maximal systolic acceleration (ACCmax) to predict ulcer healing. Secondary objectives comprised the investigation of the prognostic accuracy in patients prone to medial arterial calcification and to assess the potential risk of amputation. Methods: A single-cente...
Abstract
Cited 3 times since 2024 (4 per year)
source: EuropePMC
Journal of cardiovascular medicine (Hagerstown, Md.),
Volume 25, Issue 9, 22 4 2024, Pages 715-716
Invasive evaluation of coronary artery compliance modification after intracoronary lithotripsy.
Oliveri F, Van Oort M, Al Amri I, Bingen B, Van der Kley F, Jukema W, Montero J
Abstract
Cardiovascular revascularization medicine : including molecular interventions,
Volume 70, 22 4 2024, Pages 85-91
Intravascular lithotripsy for the treatment of peri-stent calcific lesions in saphenous vein grafts: A case series report.
Meijer M, Oliveri F, van Oort MJH, Bingen BO, van der Kley F, Jukema JW, Al Amri I, Montero-Cabezas JM
Background: Coronary artery bypass grafting (CABG) is a cornerstone treatment for coronary artery disease, with the use of saphenous vein grafts (SVGs) being prevalent. However, SVGs are susceptible to high failure rates due to graft inflammation, intimal hyperplasia, and atherosclerosis, leading to a substantial number of patients requiring revascularization. Percutaneous coronary intervention (PCI) of SVGs poses unique challenges, including increased risk of distal embolization and perforation...
Abstract
International journal of cardiology,
Volume 413, 22 4 2024, Pages 132387
Mitral valve repair with resection and non-resection techniques in Barlow's disease: A multi-center study.
Tomšič A, Holubec T, Sandoval E, Pham T, Castella M, Klautz RJM, Marsan NA, Pereda D, Palmen M
Background: Various mitral valve (MV) repair techniques are nowadays in use. Non-resection techniques, that rely exclusively on Gore-Tex® neochords and annuloplasty, have been popularized; however, their efficacy in Barlow's disease, characterized by large myxomatous leaflets, is yet unclear. Methods: Consecutive patients undergoing MV repair for Barlow's disease between 2011 and 2019 were selected on the basis of being eligible for resection and non-resection techniques. Study endpoin...
Abstract
