6882 results
Cited 13 times since 2013 (1.1 per year)
source: EuropePMC
Asian Pacific journal of cancer prevention : APJCP,
Volume 14, Issue 5, 1 1 2013, Pages 3281-3288
Determining the awareness of and compliance with breast cancer screening among Turkish residential women.
Yilmaz D, Bebis H, Ortabag T
Background: Breast cancer is the leading cause of cancer-related deaths in women. Despite being associated with high morbidity and mortality, breast cancer is a disease that can be diagnosed and treated early. Materials and methods: In this cross-sectional study of 321 women, data were collected by Questionnaire, Breast Cancer Risk Assessment Form and Champion's Health Belief Model Scale. Mann-Whitney U, Kruskal-Wallis, Chi- squared tests and logistic regression were used in the statistical...
Abstract
Cited 44 times since 2013 (3.6 per year)
source: EuropePMC
The British journal of dermatology,
Volume 168, Issue 1, 1 1 2013, Pages 93-98
Dose optimization for near-infrared fluorescence sentinel lymph node mapping in patients with melanoma.
van der Vorst JR, Schaafsma BE, Verbeek FP, Swijnenburg RJ, Hutteman M, Liefers GJ, van de Velde CJ, Frangioni JV, Vahrmeijer AL
Background: Regional lymph node involvement is the most important prognostic factor in cutaneous melanoma. As only 20% of patients with melanoma have occult nodal disease and would benefit from a regional lymphadenectomy, the sentinel lymph node (SLN) biopsy was introduced. Near-infrared (NIR) fluorescence has been hypothesized to improve SLN mapping. Objectives: To assess the potential of intraoperative NIR fluorescence imaging to improve SLN mapping in patients with melanoma and to examine t...
Abstract
Cited 3 times since 2013 (0.2 per year)
source: EuropePMC
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention,
Volume 16, Issue Pt 3, 1 1 2013, Pages 147-154
Improved myocardial scar characterization by super-resolution reconstruction in late gadolinium enhanced MRI.
Dzyubachyk O, Tao Q, Poot DH, Lamb H, Zeppenfeld K, Lelieveldt BP, van der Geest RJ
Image resolution is an important factor for accurate myocardial scar assessment from late gadolinium enhanced (LGE) MR. It has been shown that the conventionally used short-axis (SA) LGE acquisition with anisotropic resolution may overestimate the scar size due to partial volume effect, undermining the prognostic and diagnostic accuracy of LGE MRI in critical clinical applications. In this work, we present a method for combining three complementary anisotropic orthogonal LGE sequences of the hea...
Abstract
Cited 19 times since 2013 (1.6 per year)
source: EuropePMC
Indian pacing and electrophysiology journal,
Volume 13, Issue 1, 1 1 2013, Pages 14-33
Radiofrequency catheter ablation of idiopathic right ventricular outflow tract arrhythmias.
Calvo N, Jongbloed M, Zeppenfeld K
Idiopathic ventricular arrhythmias (VA) consist of various subtypes of VA that occur in the absence of clinically apparent structural heart disease. Affected patients account for approximately 10% of all patients referred for evaluation of ventricular tachycardia (VT). Arrhythmias arising from the outflow tract (OT) are the most common subtype of idiopathic VA and more than 70-80% of idiopathic VTs or premature ventricular contractions (PVCs) originate from the right ventricular (RV) OT. Idiopat...
Abstract
Cited 10 times since 2012 (0.8 per year)
source: EuropePMC
Journal of molecular and cellular cardiology,
Volume 56, 26 4 2012, Pages 116-128
Lack of haptoglobin results in unbalanced VEGFα/angiopoietin-1 expression, intramural hemorrhage and impaired wound healing after myocardial infarction.
Arslan F, Smeets MB, Buttari B, Profumo E, Riganò R, Akeroyd L, Kara E, Timmers L, Sluijter JP, van Middelaar B, den Ouden K, Pasterkamp G, Lim SK, de Kleijn DP
Decreased haptoglobin (Hp) functionality due to allelic variations is associated with worsened outcome in patients after myocardial infarction (MI). However, mechanisms through which haptoglobin deficiency impairs cardiac repair remain to be elucidated. In the present study, we identified novel molecular alterations mediated by Hp involved in early and late cardiac repair responses after left coronary artery ligation in Hp(-/-) and wild-type (WT) mice. We observed a higher mortality rate in Hp(-...
Abstract
Cited 19 times since 2012 (1.6 per year)
source: EuropePMC
Atherosclerosis,
Volume 227, Issue 1, 24 4 2012, Pages 95-99
Determinants of calcification growth in atherosclerotic carotid arteries; a serial multi-detector CT angiography study.
van Gils MJ, Bodde MC, Cremers LG, Dippel DW, van der Lugt A
Background: Little is known about the natural course of atherosclerotic plaque in the carotid artery bifurcation. This study investigated the growth pattern of calcifications in atherosclerotic carotid arteries and its determinants using serial multi-detector CT angiography (MDCTA). Methods: From a cohort of consecutive patients with TIA or ischemic stroke and a baseline MCDTA scan of the carotid arteries, subjects were invited for a follow-up scan after 4-6 years. Calcification volumes were sco...
Abstract
Cited 50 times since 2012 (4.1 per year)
source: EuropePMC
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association,
Volume 53, 21 3 2012, Pages 359-363
Radioprotection by two phenolic compounds: chlorogenic and quinic acid, on X-ray induced DNA damage in human blood lymphocytes in vitro.
Cinkilic N, Cetintas SK, Zorlu T, Vatan O, Yilmaz D, Cavas T, Tunc S, Ozkan L, Bilaloglu R
The present study was designed to determine the radioprotective effect of two phytochemicals, namely, quinic acid and chlorogenic acid, against X-ray irradiation-induced genomic instability in non-tumorigenic human blood lymphocytes. The protective ability of two phenolic acids against radiation-induced DNA damage was assessed using the alkaline comet assay in human blood lymphocytes isolated from two healthy human donors. A Siemens Mevatron MD2 (Siemens AG, USA, 1994) linear accelerator was use...
Abstract
Cited 51 times since 2012 (4.2 per year)
source: EuropePMC
PloS one,
Volume 7, Issue 12, 20 3 2012, Pages e52438
Blood pressure variability and cardiovascular risk in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER).
Poortvliet RK, Ford I, Lloyd SM, Sattar N, Mooijaart SP, de Craen AJ, Westendorp RG, Jukema JW, Packard CJ, Gussekloo J, de Ruijter W, Stott DJ
Variability in blood pressure predicts cardiovascular disease in young- and middle-aged subjects, but relevant data for older individuals are sparse. We analysed data from the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) study of 5804 participants aged 70-82 years with a history of, or risk factors for cardiovascular disease. Visit-to-visit variability in blood pressure (standard deviation) was determined using a minimum of five measurements over 1 year; an inception cohort...
Abstract
Cited 44 times since 2012 (3.6 per year)
source: EuropePMC
European journal of heart failure,
Volume 15, Issue 5, 18 3 2012, Pages 581-588
Resting heart rate and incident heart failure and cardiovascular mortality in older adults: role of inflammation and endothelial dysfunction: the PROSPER study.
Nanchen D, Stott DJ, Gussekloo J, Mooijaart SP, Westendorp RG, Jukema JW, Macfarlane PW, Cornuz J, Rodondi N, Buckley BM, Ford I, Sattar N, de Craen AJ, PROSPER Group
Aims: Resting heart rate is a promising modifiable cardiovascular risk marker in older adults, but the mechanisms linking heart rate to cardiovascular disease are not fully understood. We aimed to assess the association between resting heart rate and incident heart failure (HF) and cardiovascular mortality, and to examine whether these associations might be attributable to systemic inflammation and endothelial dysfunction. Methods and results: We studied 4084 older adults aged 70-82 years with k...
Abstract
Cited 97 times since 2012 (7.9 per year)
source: EuropePMC
Circulation,
Volume 127, Issue 3, 17 3 2012, Pages 322-330
Effect of valsartan on systemic right ventricular function: a double-blind, randomized, placebo-controlled pilot trial.
van der Bom T, Winter MM, Bouma BJ, Groenink M, Vliegen HW, Pieper PG, van Dijk AP, Sieswerda GT, Roos-Hesselink JW, Zwinderman AH, Mulder BJ
Background: The role of angiotensin II receptor blockers in patients with a systemic right ventricle has not been elucidated. Methods and results: We conducted a multicenter, double-blind, parallel, randomized controlled trial of angiotensin II receptor blocker valsartan 160 mg twice daily compared with placebo in patients with a systemic right ventricle caused by congenitally or surgically corrected transposition of the great arteries. The primary end point was change in right ventricular eject...
Abstract
Cited 7 times since 2012 (0.6 per year)
source: EuropePMC
European journal of radiology,
Volume 82, Issue 4, 14 2 2012, Pages 680-685
High field carotid vessel wall imaging: a study on reproducibility.
Kröner ES, Westenberg JJ, van der Geest RJ, Brouwer NJ, Doornbos J, Kooi ME, van der Wall EE, Lamb HJ, Siebelink HJ
Purpose: Currently, a multi-contrast protocol, including a combination of five MR-sequences is used as reference standard for morphologic imaging and quantitative measurements of the carotid artery vessel wall. The purpose of this study is to investigate the scan-rescan reproducibility together with intra- and inter-observer reproducibility of each of the five MR-sequences. Methods: Twenty healthy volunteers (55% male, mean age=26 years) underwent repeated MR-examinations (3T-Philips-MRI) of the...
Abstract
Cited 4 times since 2012 (0.3 per year)
source: EuropePMC
Case reports in pediatrics,
Volume 2012, 12 2 2012, Pages 314256
Left pulmonary artery thrombosis in a neonate with left lung hypoplasia.
van Schendel MP, Visser DH, Rammeloo LA, Hazekamp MG, Hruda J
Thrombotic events in neonates may origin from fetal life. A 4-day-old newborn infant with a family history of heterozygous type 1 protein C deficiency was diagnosed with left lung hypoplasia and left pulmonary artery thrombosis. Its source was prenatally closed ductus arteriosus. Surgical removal of the thrombus was performed.
Abstract
Cited 25 times since 2012 (2 per year)
source: EuropePMC
European heart journal. Cardiovascular Imaging,
Volume 14, Issue 8, 7 1 2012, Pages 774-781
Impact of clinical and echocardiographic response to cardiac resynchronization therapy on long-term survival.
Bertini M, Höke U, van Bommel RJ, Ng AC, Shanks M, Nucifora G, Auger D, Borleffs CJ, van Rijnsoever EP, van Erven L, Schalij MJ, Marsan NA, Bax JJ, Delgado V
Background: Clinical or echocardiographic mid-term responses to cardiac resynchronization therapy (CRT) may have a different influence on a long-term prognosis of heart failure patients treated with CRT. The aim of the evaluation was to establish which definition of response to CRT, clinical or echocardiographic, best predicts long-term prognosis. Methods and results: A total of 679 heart failure patients treated with CRT were included. All the patients underwent a complete history and physical...
Abstract
Cited 51 times since 2012 (4.2 per year)
source: EuropePMC
Clinical cancer research : an official journal of the American Association for Cancer Research,
Volume 19, Issue 3, 6 1 2012, Pages 743-751
A phase II study of sorafenib in patients with platinum-pretreated, advanced (Stage IIIb or IV) non-small cell lung cancer with a KRAS mutation.
Dingemans AM, Mellema WW, Groen HJ, van Wijk A, Burgers SA, Kunst PW, Thunnissen E, Heideman DA, Smit EF
Purpose: Sorafenib inhibits the Ras/Raf pathway, which is overactive in cancer patients with a KRAS mutation. We hypothesized that patients with non-small cell lung cancer (NSCLC) with KRAS mutation will benefit from treatment with sorafenib. Experimental design: In this phase II study, patients with KRAS-mutated, stage IIIb or IV NSCLC that progressed after at least one platinum-containing regimen were treated with sorafenib. Treatment consisted of sorafenib 400 mg twice daily until disease pro...
Abstract
European heart journal. Cardiovascular Imaging,
Volume 14, Issue 5, 5 1 2012, Pages 507
Rapid aortic aneurysm formation in Marfan patient with dissection of the entire aorta.
Scholte AJ, Hilhorst-Hofstee Y, Versteegh MI, Kroft LJ
Abstract
Cited 15 times since 2012 (1.2 per year)
source: EuropePMC
Diabetes care,
Volume 36, Issue 4, 5 1 2012, Pages 985-991
Influence of diabetes on left ventricular systolic and diastolic function and on long-term outcome after cardiac resynchronization therapy.
Höke U, Thijssen J, van Bommel RJ, van Erven L, van der Velde ET, Holman ER, Schalij MJ, Bax JJ, Delgado V, Marsan NA
Objective: The influence of diabetes on cardiac resynchronization therapy (CRT) remains unclear. The aims of the current study were to 1) assess the changes in left ventricular (LV) systolic and diastolic function and 2) evaluate long-term prognosis in CRT recipients with diabetes. Research design and methods: A total of 710 CRT recipients (171 with diabetes) were included from an ongoing registry. Echocardiographic evaluation, including LV systolic and diastolic function assessment, was perform...
Abstract
Cited 24 times since 2012 (2 per year)
source: EuropePMC
Injury,
Volume 44, Issue 4, 3 1 2012, Pages 498-503
Re-displacement of stable distal both-bone forearm fractures in children: a randomised controlled multicentre trial.
Colaris JW, Allema JH, Biter LU, de Vries MR, van de Ven CP, Bloem RM, Kerver AJ, Reijman M, Verhaar JA
Introduction: Displaced metaphyseal both-bone fractures of the distal forearm are generally reduced and stabilised by an above-elbow cast (AEC) with or without additional pinning. The purpose of this study was to find out if re-displacement of a reduced stable metaphyseal both-bone fracture of the distal forearm in a child could be prevented by stabilisation with Kirschner wires. Methods: Consecutive children aged
Abstract
Cited 58 times since 2012 (4.7 per year)
source: EuropePMC
Nature structural & molecular biology,
Volume 20, Issue 1, 2 1 2012, Pages 73-81
Eri1 degrades the stem-loop of oligouridylated histone mRNAs to induce replication-dependent decay.
Hoefig KP, Rath N, Heinz GA, Wolf C, Dameris J, Schepers A, Kremmer E, Ansel KM, Heissmeyer V
The exoRNase Eri1 inhibits RNA interference and trims the 5.8S rRNA 3' end. It also binds to the stem-loop of histone mRNAs, but the functional importance of this interaction remains elusive. Histone mRNAs are normally degraded at the end of S phase or after pharmacological inhibition of replication. Both processes are impaired in Eri1-deficient mouse cells, which instead accumulate oligouridylated histone mRNAs. Eri1 trims the mature histone mRNAs by two unpaired nucleotides at the 3'...
Abstract
Cited 7 times since 2012 (0.6 per year)
source: EuropePMC
The Annals of thoracic surgery,
Volume 94, Issue 6, 1 1 2012, Pages 2122-2125
Implantation of a left ventricular assist device in patients with a complex apical anatomy.
Palmen M, Verwey HF, Haeck ML, Holman ER, Schalij MJ, Klautz RJ
Implantation of a left ventricular assist device can be challenging in patients with an altered apical anatomy after cardiac surgery or as the result of the presence of a calcified apical aneurysm. In this paper we present 2 cases with a challenging apical anatomy and introduce a new surgical technique facilitating left ventricular assist device implantation in these patients.
Abstract
Cited 16 times since 2012 (1.3 per year)
source: EuropePMC
Expert review of cardiovascular therapy,
Volume 10, Issue 12, 1 1 2012, Pages 1517-1531
Surgical versus percutaneous treatment of aortic coarctation: new standards in an era of transcatheter repair.
Luijendijk P, Bouma BJ, Groenink M, Boekholdt M, Hazekamp MG, Blom NA, Koolbergen DR, de Winter RJ, Mulder BJ
Aortic coarctation is a common congenital cardiovascular defect, which can be diagnosed over a wide range of ages and with varying degrees of severity. Surgery has proven to be an effective treatment for the management of native aortic coarctation, and remains the treatment of choice in neonates. Balloon angioplasty with or without stenting has evolved rapidly over the past decade. Balloon angioplasty is the treatment of choice in children with re-coarctation, and currently available immediate r...
Abstract
